8IQK

Structural basis of the specificity and interaction mechanism of Bmf binding to pro-survival proteins

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0042981	biological_process	regulation of apoptotic process
B	0006915	biological_process	apoptotic process
C	0042981	biological_process	regulation of apoptotic process
D	0006915	biological_process	apoptotic process
E	0042981	biological_process	regulation of apoptotic process
F	0006915	biological_process	apoptotic process
G	0042981	biological_process	regulation of apoptotic process
H	0006915	biological_process	apoptotic process

Functional Information from PROSITE/UniProt

site_id	PS01080
Number of Residues	19
Details	BH1 Apoptosis regulator, Bcl-2 family BH1 motif signature. LFrDGv.NWGRIVAFFsFGG

Chain	Residue	Details
A	LEU130-GLY148

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site_id	PS01258
Number of Residues	12
Details	BH2 Apoptosis regulator, Bcl-2 family BH2 motif signature. WIqenGGWDtFV

Chain	Residue	Details
A	TRP181-VAL192

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site_id	PS01259
Number of Residues	15
Details	BH3 Apoptosis regulator, Bcl-2 family BH3 motif signature. VkqaLReAGDEFELR

Chain	Residue	Details
A	VAL86-ARG100

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site_id	PS01260
Number of Residues	21
Details	BH4_1 Apoptosis regulator, Bcl-2 family BH4 motif signature. SNRELVvDFLSYKLSQKGYsW

Chain	Residue	Details
A	SER4-TRP24

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	SITE: Cleavage; by caspase-1

Chain	Residue	Details
A	LEU99
C	LEU99
E	LEU99
G	LEU99

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site_id	SWS_FT_FI2
Number of Residues	4
Details	MOD_RES: Phosphoserine; by PLK3 => ECO:0000269|PubMed:21840391

Chain	Residue	Details
A	LYS87
C	LYS87
E	LYS87
G	LYS87

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site_id	SWS_FT_FI3
Number of Residues	4
Details	MOD_RES: Phosphoserine; by CDK1 => ECO:0000269|PubMed:19917720

Chain	Residue	Details
A	ARG100
C	ARG100
E	ARG100
G	ARG100

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