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8IQ0

Crystal structure of hydrogen sulfide-bound superoxide dismutase in oxidized state

Functional Information from GO Data
ChainGOidnamespacecontents
A0000209biological_processprotein polyubiquitination
A0000303biological_processresponse to superoxide
A0001541biological_processovarian follicle development
A0001819biological_processpositive regulation of cytokine production
A0001895biological_processretina homeostasis
A0002262biological_processmyeloid cell homeostasis
A0004784molecular_functionsuperoxide dismutase activity
A0004842molecular_functionubiquitin-protein transferase activity
A0005507molecular_functioncopper ion binding
A0005515molecular_functionprotein binding
A0005634cellular_componentnucleus
A0005737cellular_componentcytoplasm
A0005739cellular_componentmitochondrion
A0005777cellular_componentperoxisome
A0005829cellular_componentcytosol
A0005886cellular_componentplasma membrane
A0006749biological_processglutathione metabolic process
A0006801biological_processsuperoxide metabolic process
A0006879biological_processintracellular iron ion homeostasis
A0007283biological_processspermatogenesis
A0007566biological_processembryo implantation
A0007605biological_processsensory perception of sound
A0007626biological_processlocomotory behavior
A0008217biological_processregulation of blood pressure
A0008270molecular_functionzinc ion binding
A0009408biological_processresponse to heat
A0016209molecular_functionantioxidant activity
A0016491molecular_functionoxidoreductase activity
A0019226biological_processtransmission of nerve impulse
A0019430biological_processremoval of superoxide radicals
A0030346molecular_functionprotein phosphatase 2B binding
A0031410cellular_componentcytoplasmic vesicle
A0032287biological_processperipheral nervous system myelin maintenance
A0032839cellular_componentdendrite cytoplasm
A0032991cellular_componentprotein-containing complex
A0040014biological_processregulation of multicellular organism growth
A0042542biological_processresponse to hydrogen peroxide
A0042803molecular_functionprotein homodimerization activity
A0043025cellular_componentneuronal cell body
A0043085biological_processpositive regulation of catalytic activity
A0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
A0043410biological_processpositive regulation of MAPK cascade
A0043524biological_processnegative regulation of neuron apoptotic process
A0045471biological_processresponse to ethanol
A0046716biological_processmuscle cell cellular homeostasis
A0046872molecular_functionmetal ion binding
A0048678biological_processresponse to axon injury
A0050665biological_processhydrogen peroxide biosynthetic process
A0051087molecular_functionprotein-folding chaperone binding
A0051881biological_processregulation of mitochondrial membrane potential
A0060047biological_processheart contraction
A0060052biological_processneurofilament cytoskeleton organization
A0060087biological_processrelaxation of vascular associated smooth muscle
A0060088biological_processauditory receptor cell stereocilium organization
A0072593biological_processreactive oxygen species metabolic process
B0000209biological_processprotein polyubiquitination
B0000303biological_processresponse to superoxide
B0001541biological_processovarian follicle development
B0001819biological_processpositive regulation of cytokine production
B0001895biological_processretina homeostasis
B0002262biological_processmyeloid cell homeostasis
B0004784molecular_functionsuperoxide dismutase activity
B0004842molecular_functionubiquitin-protein transferase activity
B0005507molecular_functioncopper ion binding
B0005515molecular_functionprotein binding
B0005634cellular_componentnucleus
B0005737cellular_componentcytoplasm
B0005739cellular_componentmitochondrion
B0005777cellular_componentperoxisome
B0005829cellular_componentcytosol
B0005886cellular_componentplasma membrane
B0006749biological_processglutathione metabolic process
B0006801biological_processsuperoxide metabolic process
B0006879biological_processintracellular iron ion homeostasis
B0007283biological_processspermatogenesis
B0007566biological_processembryo implantation
B0007605biological_processsensory perception of sound
B0007626biological_processlocomotory behavior
B0008217biological_processregulation of blood pressure
B0008270molecular_functionzinc ion binding
B0009408biological_processresponse to heat
B0016209molecular_functionantioxidant activity
B0016491molecular_functionoxidoreductase activity
B0019226biological_processtransmission of nerve impulse
B0019430biological_processremoval of superoxide radicals
B0030346molecular_functionprotein phosphatase 2B binding
B0031410cellular_componentcytoplasmic vesicle
B0032287biological_processperipheral nervous system myelin maintenance
B0032839cellular_componentdendrite cytoplasm
B0032991cellular_componentprotein-containing complex
B0040014biological_processregulation of multicellular organism growth
B0042542biological_processresponse to hydrogen peroxide
B0042803molecular_functionprotein homodimerization activity
B0043025cellular_componentneuronal cell body
B0043085biological_processpositive regulation of catalytic activity
B0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
B0043410biological_processpositive regulation of MAPK cascade
B0043524biological_processnegative regulation of neuron apoptotic process
B0045471biological_processresponse to ethanol
B0046716biological_processmuscle cell cellular homeostasis
B0046872molecular_functionmetal ion binding
B0048678biological_processresponse to axon injury
B0050665biological_processhydrogen peroxide biosynthetic process
B0051087molecular_functionprotein-folding chaperone binding
B0051881biological_processregulation of mitochondrial membrane potential
B0060047biological_processheart contraction
B0060052biological_processneurofilament cytoskeleton organization
B0060087biological_processrelaxation of vascular associated smooth muscle
B0060088biological_processauditory receptor cell stereocilium organization
B0072593biological_processreactive oxygen species metabolic process
C0000209biological_processprotein polyubiquitination
C0000303biological_processresponse to superoxide
C0001541biological_processovarian follicle development
C0001819biological_processpositive regulation of cytokine production
C0001895biological_processretina homeostasis
C0002262biological_processmyeloid cell homeostasis
C0004784molecular_functionsuperoxide dismutase activity
C0004842molecular_functionubiquitin-protein transferase activity
C0005507molecular_functioncopper ion binding
C0005515molecular_functionprotein binding
C0005634cellular_componentnucleus
C0005737cellular_componentcytoplasm
C0005739cellular_componentmitochondrion
C0005777cellular_componentperoxisome
C0005829cellular_componentcytosol
C0005886cellular_componentplasma membrane
C0006749biological_processglutathione metabolic process
C0006801biological_processsuperoxide metabolic process
C0006879biological_processintracellular iron ion homeostasis
C0007283biological_processspermatogenesis
C0007566biological_processembryo implantation
C0007605biological_processsensory perception of sound
C0007626biological_processlocomotory behavior
C0008217biological_processregulation of blood pressure
C0008270molecular_functionzinc ion binding
C0009408biological_processresponse to heat
C0016209molecular_functionantioxidant activity
C0016491molecular_functionoxidoreductase activity
C0019226biological_processtransmission of nerve impulse
C0019430biological_processremoval of superoxide radicals
C0030346molecular_functionprotein phosphatase 2B binding
C0031410cellular_componentcytoplasmic vesicle
C0032287biological_processperipheral nervous system myelin maintenance
C0032839cellular_componentdendrite cytoplasm
C0032991cellular_componentprotein-containing complex
C0040014biological_processregulation of multicellular organism growth
C0042542biological_processresponse to hydrogen peroxide
C0042803molecular_functionprotein homodimerization activity
C0043025cellular_componentneuronal cell body
C0043085biological_processpositive regulation of catalytic activity
C0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
C0043410biological_processpositive regulation of MAPK cascade
C0043524biological_processnegative regulation of neuron apoptotic process
C0045471biological_processresponse to ethanol
C0046716biological_processmuscle cell cellular homeostasis
C0046872molecular_functionmetal ion binding
C0048678biological_processresponse to axon injury
C0050665biological_processhydrogen peroxide biosynthetic process
C0051087molecular_functionprotein-folding chaperone binding
C0051881biological_processregulation of mitochondrial membrane potential
C0060047biological_processheart contraction
C0060052biological_processneurofilament cytoskeleton organization
C0060087biological_processrelaxation of vascular associated smooth muscle
C0060088biological_processauditory receptor cell stereocilium organization
C0072593biological_processreactive oxygen species metabolic process
D0000209biological_processprotein polyubiquitination
D0000303biological_processresponse to superoxide
D0001541biological_processovarian follicle development
D0001819biological_processpositive regulation of cytokine production
D0001895biological_processretina homeostasis
D0002262biological_processmyeloid cell homeostasis
D0004784molecular_functionsuperoxide dismutase activity
D0004842molecular_functionubiquitin-protein transferase activity
D0005507molecular_functioncopper ion binding
D0005515molecular_functionprotein binding
D0005634cellular_componentnucleus
D0005737cellular_componentcytoplasm
D0005739cellular_componentmitochondrion
D0005777cellular_componentperoxisome
D0005829cellular_componentcytosol
D0005886cellular_componentplasma membrane
D0006749biological_processglutathione metabolic process
D0006801biological_processsuperoxide metabolic process
D0006879biological_processintracellular iron ion homeostasis
D0007283biological_processspermatogenesis
D0007566biological_processembryo implantation
D0007605biological_processsensory perception of sound
D0007626biological_processlocomotory behavior
D0008217biological_processregulation of blood pressure
D0008270molecular_functionzinc ion binding
D0009408biological_processresponse to heat
D0016209molecular_functionantioxidant activity
D0016491molecular_functionoxidoreductase activity
D0019226biological_processtransmission of nerve impulse
D0019430biological_processremoval of superoxide radicals
D0030346molecular_functionprotein phosphatase 2B binding
D0031410cellular_componentcytoplasmic vesicle
D0032287biological_processperipheral nervous system myelin maintenance
D0032839cellular_componentdendrite cytoplasm
D0032991cellular_componentprotein-containing complex
D0040014biological_processregulation of multicellular organism growth
D0042542biological_processresponse to hydrogen peroxide
D0042803molecular_functionprotein homodimerization activity
D0043025cellular_componentneuronal cell body
D0043085biological_processpositive regulation of catalytic activity
D0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
D0043410biological_processpositive regulation of MAPK cascade
D0043524biological_processnegative regulation of neuron apoptotic process
D0045471biological_processresponse to ethanol
D0046716biological_processmuscle cell cellular homeostasis
D0046872molecular_functionmetal ion binding
D0048678biological_processresponse to axon injury
D0050665biological_processhydrogen peroxide biosynthetic process
D0051087molecular_functionprotein-folding chaperone binding
D0051881biological_processregulation of mitochondrial membrane potential
D0060047biological_processheart contraction
D0060052biological_processneurofilament cytoskeleton organization
D0060087biological_processrelaxation of vascular associated smooth muscle
D0060088biological_processauditory receptor cell stereocilium organization
D0072593biological_processreactive oxygen species metabolic process
E0000209biological_processprotein polyubiquitination
E0000303biological_processresponse to superoxide
E0001541biological_processovarian follicle development
E0001819biological_processpositive regulation of cytokine production
E0001895biological_processretina homeostasis
E0002262biological_processmyeloid cell homeostasis
E0004784molecular_functionsuperoxide dismutase activity
E0004842molecular_functionubiquitin-protein transferase activity
E0005507molecular_functioncopper ion binding
E0005515molecular_functionprotein binding
E0005634cellular_componentnucleus
E0005737cellular_componentcytoplasm
E0005739cellular_componentmitochondrion
E0005777cellular_componentperoxisome
E0005829cellular_componentcytosol
E0005886cellular_componentplasma membrane
E0006749biological_processglutathione metabolic process
E0006801biological_processsuperoxide metabolic process
E0006879biological_processintracellular iron ion homeostasis
E0007283biological_processspermatogenesis
E0007566biological_processembryo implantation
E0007605biological_processsensory perception of sound
E0007626biological_processlocomotory behavior
E0008217biological_processregulation of blood pressure
E0008270molecular_functionzinc ion binding
E0009408biological_processresponse to heat
E0016209molecular_functionantioxidant activity
E0016491molecular_functionoxidoreductase activity
E0019226biological_processtransmission of nerve impulse
E0019430biological_processremoval of superoxide radicals
E0030346molecular_functionprotein phosphatase 2B binding
E0031410cellular_componentcytoplasmic vesicle
E0032287biological_processperipheral nervous system myelin maintenance
E0032839cellular_componentdendrite cytoplasm
E0032991cellular_componentprotein-containing complex
E0040014biological_processregulation of multicellular organism growth
E0042542biological_processresponse to hydrogen peroxide
E0042803molecular_functionprotein homodimerization activity
E0043025cellular_componentneuronal cell body
E0043085biological_processpositive regulation of catalytic activity
E0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
E0043410biological_processpositive regulation of MAPK cascade
E0043524biological_processnegative regulation of neuron apoptotic process
E0045471biological_processresponse to ethanol
E0046716biological_processmuscle cell cellular homeostasis
E0046872molecular_functionmetal ion binding
E0048678biological_processresponse to axon injury
E0050665biological_processhydrogen peroxide biosynthetic process
E0051087molecular_functionprotein-folding chaperone binding
E0051881biological_processregulation of mitochondrial membrane potential
E0060047biological_processheart contraction
E0060052biological_processneurofilament cytoskeleton organization
E0060087biological_processrelaxation of vascular associated smooth muscle
E0060088biological_processauditory receptor cell stereocilium organization
E0072593biological_processreactive oxygen species metabolic process
F0000209biological_processprotein polyubiquitination
F0000303biological_processresponse to superoxide
F0001541biological_processovarian follicle development
F0001819biological_processpositive regulation of cytokine production
F0001895biological_processretina homeostasis
F0002262biological_processmyeloid cell homeostasis
F0004784molecular_functionsuperoxide dismutase activity
F0004842molecular_functionubiquitin-protein transferase activity
F0005507molecular_functioncopper ion binding
F0005515molecular_functionprotein binding
F0005634cellular_componentnucleus
F0005737cellular_componentcytoplasm
F0005739cellular_componentmitochondrion
F0005777cellular_componentperoxisome
F0005829cellular_componentcytosol
F0005886cellular_componentplasma membrane
F0006749biological_processglutathione metabolic process
F0006801biological_processsuperoxide metabolic process
F0006879biological_processintracellular iron ion homeostasis
F0007283biological_processspermatogenesis
F0007566biological_processembryo implantation
F0007605biological_processsensory perception of sound
F0007626biological_processlocomotory behavior
F0008217biological_processregulation of blood pressure
F0008270molecular_functionzinc ion binding
F0009408biological_processresponse to heat
F0016209molecular_functionantioxidant activity
F0016491molecular_functionoxidoreductase activity
F0019226biological_processtransmission of nerve impulse
F0019430biological_processremoval of superoxide radicals
F0030346molecular_functionprotein phosphatase 2B binding
F0031410cellular_componentcytoplasmic vesicle
F0032287biological_processperipheral nervous system myelin maintenance
F0032839cellular_componentdendrite cytoplasm
F0032991cellular_componentprotein-containing complex
F0040014biological_processregulation of multicellular organism growth
F0042542biological_processresponse to hydrogen peroxide
F0042803molecular_functionprotein homodimerization activity
F0043025cellular_componentneuronal cell body
F0043085biological_processpositive regulation of catalytic activity
F0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
F0043410biological_processpositive regulation of MAPK cascade
F0043524biological_processnegative regulation of neuron apoptotic process
F0045471biological_processresponse to ethanol
F0046716biological_processmuscle cell cellular homeostasis
F0046872molecular_functionmetal ion binding
F0048678biological_processresponse to axon injury
F0050665biological_processhydrogen peroxide biosynthetic process
F0051087molecular_functionprotein-folding chaperone binding
F0051881biological_processregulation of mitochondrial membrane potential
F0060047biological_processheart contraction
F0060052biological_processneurofilament cytoskeleton organization
F0060087biological_processrelaxation of vascular associated smooth muscle
F0060088biological_processauditory receptor cell stereocilium organization
F0072593biological_processreactive oxygen species metabolic process
G0000209biological_processprotein polyubiquitination
G0000303biological_processresponse to superoxide
G0001541biological_processovarian follicle development
G0001819biological_processpositive regulation of cytokine production
G0001895biological_processretina homeostasis
G0002262biological_processmyeloid cell homeostasis
G0004784molecular_functionsuperoxide dismutase activity
G0004842molecular_functionubiquitin-protein transferase activity
G0005507molecular_functioncopper ion binding
G0005515molecular_functionprotein binding
G0005634cellular_componentnucleus
G0005737cellular_componentcytoplasm
G0005739cellular_componentmitochondrion
G0005777cellular_componentperoxisome
G0005829cellular_componentcytosol
G0005886cellular_componentplasma membrane
G0006749biological_processglutathione metabolic process
G0006801biological_processsuperoxide metabolic process
G0006879biological_processintracellular iron ion homeostasis
G0007283biological_processspermatogenesis
G0007566biological_processembryo implantation
G0007605biological_processsensory perception of sound
G0007626biological_processlocomotory behavior
G0008217biological_processregulation of blood pressure
G0008270molecular_functionzinc ion binding
G0009408biological_processresponse to heat
G0016209molecular_functionantioxidant activity
G0016491molecular_functionoxidoreductase activity
G0019226biological_processtransmission of nerve impulse
G0019430biological_processremoval of superoxide radicals
G0030346molecular_functionprotein phosphatase 2B binding
G0031410cellular_componentcytoplasmic vesicle
G0032287biological_processperipheral nervous system myelin maintenance
G0032839cellular_componentdendrite cytoplasm
G0032991cellular_componentprotein-containing complex
G0040014biological_processregulation of multicellular organism growth
G0042542biological_processresponse to hydrogen peroxide
G0042803molecular_functionprotein homodimerization activity
G0043025cellular_componentneuronal cell body
G0043085biological_processpositive regulation of catalytic activity
G0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
G0043410biological_processpositive regulation of MAPK cascade
G0043524biological_processnegative regulation of neuron apoptotic process
G0045471biological_processresponse to ethanol
G0046716biological_processmuscle cell cellular homeostasis
G0046872molecular_functionmetal ion binding
G0048678biological_processresponse to axon injury
G0050665biological_processhydrogen peroxide biosynthetic process
G0051087molecular_functionprotein-folding chaperone binding
G0051881biological_processregulation of mitochondrial membrane potential
G0060047biological_processheart contraction
G0060052biological_processneurofilament cytoskeleton organization
G0060087biological_processrelaxation of vascular associated smooth muscle
G0060088biological_processauditory receptor cell stereocilium organization
G0072593biological_processreactive oxygen species metabolic process
H0000209biological_processprotein polyubiquitination
H0000303biological_processresponse to superoxide
H0001541biological_processovarian follicle development
H0001819biological_processpositive regulation of cytokine production
H0001895biological_processretina homeostasis
H0002262biological_processmyeloid cell homeostasis
H0004784molecular_functionsuperoxide dismutase activity
H0004842molecular_functionubiquitin-protein transferase activity
H0005507molecular_functioncopper ion binding
H0005515molecular_functionprotein binding
H0005634cellular_componentnucleus
H0005737cellular_componentcytoplasm
H0005739cellular_componentmitochondrion
H0005777cellular_componentperoxisome
H0005829cellular_componentcytosol
H0005886cellular_componentplasma membrane
H0006749biological_processglutathione metabolic process
H0006801biological_processsuperoxide metabolic process
H0006879biological_processintracellular iron ion homeostasis
H0007283biological_processspermatogenesis
H0007566biological_processembryo implantation
H0007605biological_processsensory perception of sound
H0007626biological_processlocomotory behavior
H0008217biological_processregulation of blood pressure
H0008270molecular_functionzinc ion binding
H0009408biological_processresponse to heat
H0016209molecular_functionantioxidant activity
H0016491molecular_functionoxidoreductase activity
H0019226biological_processtransmission of nerve impulse
H0019430biological_processremoval of superoxide radicals
H0030346molecular_functionprotein phosphatase 2B binding
H0031410cellular_componentcytoplasmic vesicle
H0032287biological_processperipheral nervous system myelin maintenance
H0032839cellular_componentdendrite cytoplasm
H0032991cellular_componentprotein-containing complex
H0040014biological_processregulation of multicellular organism growth
H0042542biological_processresponse to hydrogen peroxide
H0042803molecular_functionprotein homodimerization activity
H0043025cellular_componentneuronal cell body
H0043085biological_processpositive regulation of catalytic activity
H0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
H0043410biological_processpositive regulation of MAPK cascade
H0043524biological_processnegative regulation of neuron apoptotic process
H0045471biological_processresponse to ethanol
H0046716biological_processmuscle cell cellular homeostasis
H0046872molecular_functionmetal ion binding
H0048678biological_processresponse to axon injury
H0050665biological_processhydrogen peroxide biosynthetic process
H0051087molecular_functionprotein-folding chaperone binding
H0051881biological_processregulation of mitochondrial membrane potential
H0060047biological_processheart contraction
H0060052biological_processneurofilament cytoskeleton organization
H0060087biological_processrelaxation of vascular associated smooth muscle
H0060088biological_processauditory receptor cell stereocilium organization
H0072593biological_processreactive oxygen species metabolic process
I0000209biological_processprotein polyubiquitination
I0000303biological_processresponse to superoxide
I0001541biological_processovarian follicle development
I0001819biological_processpositive regulation of cytokine production
I0001895biological_processretina homeostasis
I0002262biological_processmyeloid cell homeostasis
I0004784molecular_functionsuperoxide dismutase activity
I0004842molecular_functionubiquitin-protein transferase activity
I0005507molecular_functioncopper ion binding
I0005515molecular_functionprotein binding
I0005634cellular_componentnucleus
I0005737cellular_componentcytoplasm
I0005739cellular_componentmitochondrion
I0005777cellular_componentperoxisome
I0005829cellular_componentcytosol
I0005886cellular_componentplasma membrane
I0006749biological_processglutathione metabolic process
I0006801biological_processsuperoxide metabolic process
I0006879biological_processintracellular iron ion homeostasis
I0007283biological_processspermatogenesis
I0007566biological_processembryo implantation
I0007605biological_processsensory perception of sound
I0007626biological_processlocomotory behavior
I0008217biological_processregulation of blood pressure
I0008270molecular_functionzinc ion binding
I0009408biological_processresponse to heat
I0016209molecular_functionantioxidant activity
I0016491molecular_functionoxidoreductase activity
I0019226biological_processtransmission of nerve impulse
I0019430biological_processremoval of superoxide radicals
I0030346molecular_functionprotein phosphatase 2B binding
I0031410cellular_componentcytoplasmic vesicle
I0032287biological_processperipheral nervous system myelin maintenance
I0032839cellular_componentdendrite cytoplasm
I0032991cellular_componentprotein-containing complex
I0040014biological_processregulation of multicellular organism growth
I0042542biological_processresponse to hydrogen peroxide
I0042803molecular_functionprotein homodimerization activity
I0043025cellular_componentneuronal cell body
I0043085biological_processpositive regulation of catalytic activity
I0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
I0043410biological_processpositive regulation of MAPK cascade
I0043524biological_processnegative regulation of neuron apoptotic process
I0045471biological_processresponse to ethanol
I0046716biological_processmuscle cell cellular homeostasis
I0046872molecular_functionmetal ion binding
I0048678biological_processresponse to axon injury
I0050665biological_processhydrogen peroxide biosynthetic process
I0051087molecular_functionprotein-folding chaperone binding
I0051881biological_processregulation of mitochondrial membrane potential
I0060047biological_processheart contraction
I0060052biological_processneurofilament cytoskeleton organization
I0060087biological_processrelaxation of vascular associated smooth muscle
I0060088biological_processauditory receptor cell stereocilium organization
I0072593biological_processreactive oxygen species metabolic process
J0000209biological_processprotein polyubiquitination
J0000303biological_processresponse to superoxide
J0001541biological_processovarian follicle development
J0001819biological_processpositive regulation of cytokine production
J0001895biological_processretina homeostasis
J0002262biological_processmyeloid cell homeostasis
J0004784molecular_functionsuperoxide dismutase activity
J0004842molecular_functionubiquitin-protein transferase activity
J0005507molecular_functioncopper ion binding
J0005515molecular_functionprotein binding
J0005634cellular_componentnucleus
J0005737cellular_componentcytoplasm
J0005739cellular_componentmitochondrion
J0005777cellular_componentperoxisome
J0005829cellular_componentcytosol
J0005886cellular_componentplasma membrane
J0006749biological_processglutathione metabolic process
J0006801biological_processsuperoxide metabolic process
J0006879biological_processintracellular iron ion homeostasis
J0007283biological_processspermatogenesis
J0007566biological_processembryo implantation
J0007605biological_processsensory perception of sound
J0007626biological_processlocomotory behavior
J0008217biological_processregulation of blood pressure
J0008270molecular_functionzinc ion binding
J0009408biological_processresponse to heat
J0016209molecular_functionantioxidant activity
J0016491molecular_functionoxidoreductase activity
J0019226biological_processtransmission of nerve impulse
J0019430biological_processremoval of superoxide radicals
J0030346molecular_functionprotein phosphatase 2B binding
J0031410cellular_componentcytoplasmic vesicle
J0032287biological_processperipheral nervous system myelin maintenance
J0032839cellular_componentdendrite cytoplasm
J0032991cellular_componentprotein-containing complex
J0040014biological_processregulation of multicellular organism growth
J0042542biological_processresponse to hydrogen peroxide
J0042803molecular_functionprotein homodimerization activity
J0043025cellular_componentneuronal cell body
J0043085biological_processpositive regulation of catalytic activity
J0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
J0043410biological_processpositive regulation of MAPK cascade
J0043524biological_processnegative regulation of neuron apoptotic process
J0045471biological_processresponse to ethanol
J0046716biological_processmuscle cell cellular homeostasis
J0046872molecular_functionmetal ion binding
J0048678biological_processresponse to axon injury
J0050665biological_processhydrogen peroxide biosynthetic process
J0051087molecular_functionprotein-folding chaperone binding
J0051881biological_processregulation of mitochondrial membrane potential
J0060047biological_processheart contraction
J0060052biological_processneurofilament cytoskeleton organization
J0060087biological_processrelaxation of vascular associated smooth muscle
J0060088biological_processauditory receptor cell stereocilium organization
J0072593biological_processreactive oxygen species metabolic process
K0000209biological_processprotein polyubiquitination
K0000303biological_processresponse to superoxide
K0001541biological_processovarian follicle development
K0001819biological_processpositive regulation of cytokine production
K0001895biological_processretina homeostasis
K0002262biological_processmyeloid cell homeostasis
K0004784molecular_functionsuperoxide dismutase activity
K0004842molecular_functionubiquitin-protein transferase activity
K0005507molecular_functioncopper ion binding
K0005515molecular_functionprotein binding
K0005634cellular_componentnucleus
K0005737cellular_componentcytoplasm
K0005739cellular_componentmitochondrion
K0005777cellular_componentperoxisome
K0005829cellular_componentcytosol
K0005886cellular_componentplasma membrane
K0006749biological_processglutathione metabolic process
K0006801biological_processsuperoxide metabolic process
K0006879biological_processintracellular iron ion homeostasis
K0007283biological_processspermatogenesis
K0007566biological_processembryo implantation
K0007605biological_processsensory perception of sound
K0007626biological_processlocomotory behavior
K0008217biological_processregulation of blood pressure
K0008270molecular_functionzinc ion binding
K0009408biological_processresponse to heat
K0016209molecular_functionantioxidant activity
K0016491molecular_functionoxidoreductase activity
K0019226biological_processtransmission of nerve impulse
K0019430biological_processremoval of superoxide radicals
K0030346molecular_functionprotein phosphatase 2B binding
K0031410cellular_componentcytoplasmic vesicle
K0032287biological_processperipheral nervous system myelin maintenance
K0032839cellular_componentdendrite cytoplasm
K0032991cellular_componentprotein-containing complex
K0040014biological_processregulation of multicellular organism growth
K0042542biological_processresponse to hydrogen peroxide
K0042803molecular_functionprotein homodimerization activity
K0043025cellular_componentneuronal cell body
K0043085biological_processpositive regulation of catalytic activity
K0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
K0043410biological_processpositive regulation of MAPK cascade
K0043524biological_processnegative regulation of neuron apoptotic process
K0045471biological_processresponse to ethanol
K0046716biological_processmuscle cell cellular homeostasis
K0046872molecular_functionmetal ion binding
K0048678biological_processresponse to axon injury
K0050665biological_processhydrogen peroxide biosynthetic process
K0051087molecular_functionprotein-folding chaperone binding
K0051881biological_processregulation of mitochondrial membrane potential
K0060047biological_processheart contraction
K0060052biological_processneurofilament cytoskeleton organization
K0060087biological_processrelaxation of vascular associated smooth muscle
K0060088biological_processauditory receptor cell stereocilium organization
K0072593biological_processreactive oxygen species metabolic process
L0000209biological_processprotein polyubiquitination
L0000303biological_processresponse to superoxide
L0001541biological_processovarian follicle development
L0001819biological_processpositive regulation of cytokine production
L0001895biological_processretina homeostasis
L0002262biological_processmyeloid cell homeostasis
L0004784molecular_functionsuperoxide dismutase activity
L0004842molecular_functionubiquitin-protein transferase activity
L0005507molecular_functioncopper ion binding
L0005515molecular_functionprotein binding
L0005634cellular_componentnucleus
L0005737cellular_componentcytoplasm
L0005739cellular_componentmitochondrion
L0005777cellular_componentperoxisome
L0005829cellular_componentcytosol
L0005886cellular_componentplasma membrane
L0006749biological_processglutathione metabolic process
L0006801biological_processsuperoxide metabolic process
L0006879biological_processintracellular iron ion homeostasis
L0007283biological_processspermatogenesis
L0007566biological_processembryo implantation
L0007605biological_processsensory perception of sound
L0007626biological_processlocomotory behavior
L0008217biological_processregulation of blood pressure
L0008270molecular_functionzinc ion binding
L0009408biological_processresponse to heat
L0016209molecular_functionantioxidant activity
L0016491molecular_functionoxidoreductase activity
L0019226biological_processtransmission of nerve impulse
L0019430biological_processremoval of superoxide radicals
L0030346molecular_functionprotein phosphatase 2B binding
L0031410cellular_componentcytoplasmic vesicle
L0032287biological_processperipheral nervous system myelin maintenance
L0032839cellular_componentdendrite cytoplasm
L0032991cellular_componentprotein-containing complex
L0040014biological_processregulation of multicellular organism growth
L0042542biological_processresponse to hydrogen peroxide
L0042803molecular_functionprotein homodimerization activity
L0043025cellular_componentneuronal cell body
L0043085biological_processpositive regulation of catalytic activity
L0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
L0043410biological_processpositive regulation of MAPK cascade
L0043524biological_processnegative regulation of neuron apoptotic process
L0045471biological_processresponse to ethanol
L0046716biological_processmuscle cell cellular homeostasis
L0046872molecular_functionmetal ion binding
L0048678biological_processresponse to axon injury
L0050665biological_processhydrogen peroxide biosynthetic process
L0051087molecular_functionprotein-folding chaperone binding
L0051881biological_processregulation of mitochondrial membrane potential
L0060047biological_processheart contraction
L0060052biological_processneurofilament cytoskeleton organization
L0060087biological_processrelaxation of vascular associated smooth muscle
L0060088biological_processauditory receptor cell stereocilium organization
L0072593biological_processreactive oxygen species metabolic process
M0000209biological_processprotein polyubiquitination
M0000303biological_processresponse to superoxide
M0001541biological_processovarian follicle development
M0001819biological_processpositive regulation of cytokine production
M0001895biological_processretina homeostasis
M0002262biological_processmyeloid cell homeostasis
M0004784molecular_functionsuperoxide dismutase activity
M0004842molecular_functionubiquitin-protein transferase activity
M0005507molecular_functioncopper ion binding
M0005515molecular_functionprotein binding
M0005634cellular_componentnucleus
M0005737cellular_componentcytoplasm
M0005739cellular_componentmitochondrion
M0005777cellular_componentperoxisome
M0005829cellular_componentcytosol
M0005886cellular_componentplasma membrane
M0006749biological_processglutathione metabolic process
M0006801biological_processsuperoxide metabolic process
M0006879biological_processintracellular iron ion homeostasis
M0007283biological_processspermatogenesis
M0007566biological_processembryo implantation
M0007605biological_processsensory perception of sound
M0007626biological_processlocomotory behavior
M0008217biological_processregulation of blood pressure
M0008270molecular_functionzinc ion binding
M0009408biological_processresponse to heat
M0016209molecular_functionantioxidant activity
M0016491molecular_functionoxidoreductase activity
M0019226biological_processtransmission of nerve impulse
M0019430biological_processremoval of superoxide radicals
M0030346molecular_functionprotein phosphatase 2B binding
M0031410cellular_componentcytoplasmic vesicle
M0032287biological_processperipheral nervous system myelin maintenance
M0032839cellular_componentdendrite cytoplasm
M0032991cellular_componentprotein-containing complex
M0040014biological_processregulation of multicellular organism growth
M0042542biological_processresponse to hydrogen peroxide
M0042803molecular_functionprotein homodimerization activity
M0043025cellular_componentneuronal cell body
M0043085biological_processpositive regulation of catalytic activity
M0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
M0043410biological_processpositive regulation of MAPK cascade
M0043524biological_processnegative regulation of neuron apoptotic process
M0045471biological_processresponse to ethanol
M0046716biological_processmuscle cell cellular homeostasis
M0046872molecular_functionmetal ion binding
M0048678biological_processresponse to axon injury
M0050665biological_processhydrogen peroxide biosynthetic process
M0051087molecular_functionprotein-folding chaperone binding
M0051881biological_processregulation of mitochondrial membrane potential
M0060047biological_processheart contraction
M0060052biological_processneurofilament cytoskeleton organization
M0060087biological_processrelaxation of vascular associated smooth muscle
M0060088biological_processauditory receptor cell stereocilium organization
M0072593biological_processreactive oxygen species metabolic process
N0000209biological_processprotein polyubiquitination
N0000303biological_processresponse to superoxide
N0001541biological_processovarian follicle development
N0001819biological_processpositive regulation of cytokine production
N0001895biological_processretina homeostasis
N0002262biological_processmyeloid cell homeostasis
N0004784molecular_functionsuperoxide dismutase activity
N0004842molecular_functionubiquitin-protein transferase activity
N0005507molecular_functioncopper ion binding
N0005515molecular_functionprotein binding
N0005634cellular_componentnucleus
N0005737cellular_componentcytoplasm
N0005739cellular_componentmitochondrion
N0005777cellular_componentperoxisome
N0005829cellular_componentcytosol
N0005886cellular_componentplasma membrane
N0006749biological_processglutathione metabolic process
N0006801biological_processsuperoxide metabolic process
N0006879biological_processintracellular iron ion homeostasis
N0007283biological_processspermatogenesis
N0007566biological_processembryo implantation
N0007605biological_processsensory perception of sound
N0007626biological_processlocomotory behavior
N0008217biological_processregulation of blood pressure
N0008270molecular_functionzinc ion binding
N0009408biological_processresponse to heat
N0016209molecular_functionantioxidant activity
N0016491molecular_functionoxidoreductase activity
N0019226biological_processtransmission of nerve impulse
N0019430biological_processremoval of superoxide radicals
N0030346molecular_functionprotein phosphatase 2B binding
N0031410cellular_componentcytoplasmic vesicle
N0032287biological_processperipheral nervous system myelin maintenance
N0032839cellular_componentdendrite cytoplasm
N0032991cellular_componentprotein-containing complex
N0040014biological_processregulation of multicellular organism growth
N0042542biological_processresponse to hydrogen peroxide
N0042803molecular_functionprotein homodimerization activity
N0043025cellular_componentneuronal cell body
N0043085biological_processpositive regulation of catalytic activity
N0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
N0043410biological_processpositive regulation of MAPK cascade
N0043524biological_processnegative regulation of neuron apoptotic process
N0045471biological_processresponse to ethanol
N0046716biological_processmuscle cell cellular homeostasis
N0046872molecular_functionmetal ion binding
N0048678biological_processresponse to axon injury
N0050665biological_processhydrogen peroxide biosynthetic process
N0051087molecular_functionprotein-folding chaperone binding
N0051881biological_processregulation of mitochondrial membrane potential
N0060047biological_processheart contraction
N0060052biological_processneurofilament cytoskeleton organization
N0060087biological_processrelaxation of vascular associated smooth muscle
N0060088biological_processauditory receptor cell stereocilium organization
N0072593biological_processreactive oxygen species metabolic process
O0000209biological_processprotein polyubiquitination
O0000303biological_processresponse to superoxide
O0001541biological_processovarian follicle development
O0001819biological_processpositive regulation of cytokine production
O0001895biological_processretina homeostasis
O0002262biological_processmyeloid cell homeostasis
O0004784molecular_functionsuperoxide dismutase activity
O0004842molecular_functionubiquitin-protein transferase activity
O0005507molecular_functioncopper ion binding
O0005515molecular_functionprotein binding
O0005634cellular_componentnucleus
O0005737cellular_componentcytoplasm
O0005739cellular_componentmitochondrion
O0005777cellular_componentperoxisome
O0005829cellular_componentcytosol
O0005886cellular_componentplasma membrane
O0006749biological_processglutathione metabolic process
O0006801biological_processsuperoxide metabolic process
O0006879biological_processintracellular iron ion homeostasis
O0007283biological_processspermatogenesis
O0007566biological_processembryo implantation
O0007605biological_processsensory perception of sound
O0007626biological_processlocomotory behavior
O0008217biological_processregulation of blood pressure
O0008270molecular_functionzinc ion binding
O0009408biological_processresponse to heat
O0016209molecular_functionantioxidant activity
O0016491molecular_functionoxidoreductase activity
O0019226biological_processtransmission of nerve impulse
O0019430biological_processremoval of superoxide radicals
O0030346molecular_functionprotein phosphatase 2B binding
O0031410cellular_componentcytoplasmic vesicle
O0032287biological_processperipheral nervous system myelin maintenance
O0032839cellular_componentdendrite cytoplasm
O0032991cellular_componentprotein-containing complex
O0040014biological_processregulation of multicellular organism growth
O0042542biological_processresponse to hydrogen peroxide
O0042803molecular_functionprotein homodimerization activity
O0043025cellular_componentneuronal cell body
O0043085biological_processpositive regulation of catalytic activity
O0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
O0043410biological_processpositive regulation of MAPK cascade
O0043524biological_processnegative regulation of neuron apoptotic process
O0045471biological_processresponse to ethanol
O0046716biological_processmuscle cell cellular homeostasis
O0046872molecular_functionmetal ion binding
O0048678biological_processresponse to axon injury
O0050665biological_processhydrogen peroxide biosynthetic process
O0051087molecular_functionprotein-folding chaperone binding
O0051881biological_processregulation of mitochondrial membrane potential
O0060047biological_processheart contraction
O0060052biological_processneurofilament cytoskeleton organization
O0060087biological_processrelaxation of vascular associated smooth muscle
O0060088biological_processauditory receptor cell stereocilium organization
O0072593biological_processreactive oxygen species metabolic process
P0000209biological_processprotein polyubiquitination
P0000303biological_processresponse to superoxide
P0001541biological_processovarian follicle development
P0001819biological_processpositive regulation of cytokine production
P0001895biological_processretina homeostasis
P0002262biological_processmyeloid cell homeostasis
P0004784molecular_functionsuperoxide dismutase activity
P0004842molecular_functionubiquitin-protein transferase activity
P0005507molecular_functioncopper ion binding
P0005515molecular_functionprotein binding
P0005634cellular_componentnucleus
P0005737cellular_componentcytoplasm
P0005739cellular_componentmitochondrion
P0005777cellular_componentperoxisome
P0005829cellular_componentcytosol
P0005886cellular_componentplasma membrane
P0006749biological_processglutathione metabolic process
P0006801biological_processsuperoxide metabolic process
P0006879biological_processintracellular iron ion homeostasis
P0007283biological_processspermatogenesis
P0007566biological_processembryo implantation
P0007605biological_processsensory perception of sound
P0007626biological_processlocomotory behavior
P0008217biological_processregulation of blood pressure
P0008270molecular_functionzinc ion binding
P0009408biological_processresponse to heat
P0016209molecular_functionantioxidant activity
P0016491molecular_functionoxidoreductase activity
P0019226biological_processtransmission of nerve impulse
P0019430biological_processremoval of superoxide radicals
P0030346molecular_functionprotein phosphatase 2B binding
P0031410cellular_componentcytoplasmic vesicle
P0032287biological_processperipheral nervous system myelin maintenance
P0032839cellular_componentdendrite cytoplasm
P0032991cellular_componentprotein-containing complex
P0040014biological_processregulation of multicellular organism growth
P0042542biological_processresponse to hydrogen peroxide
P0042803molecular_functionprotein homodimerization activity
P0043025cellular_componentneuronal cell body
P0043085biological_processpositive regulation of catalytic activity
P0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
P0043410biological_processpositive regulation of MAPK cascade
P0043524biological_processnegative regulation of neuron apoptotic process
P0045471biological_processresponse to ethanol
P0046716biological_processmuscle cell cellular homeostasis
P0046872molecular_functionmetal ion binding
P0048678biological_processresponse to axon injury
P0050665biological_processhydrogen peroxide biosynthetic process
P0051087molecular_functionprotein-folding chaperone binding
P0051881biological_processregulation of mitochondrial membrane potential
P0060047biological_processheart contraction
P0060052biological_processneurofilament cytoskeleton organization
P0060087biological_processrelaxation of vascular associated smooth muscle
P0060088biological_processauditory receptor cell stereocilium organization
P0072593biological_processreactive oxygen species metabolic process
Functional Information from PROSITE/UniProt
site_idPS00087
Number of Residues11
DetailsSOD_CU_ZN_1 Copper/Zinc superoxide dismutase signature 1. GFHVHQfGDnT
ChainResidueDetails
AGLY42-THR52

site_idPS00332
Number of Residues12
DetailsSOD_CU_ZN_2 Copper/Zinc superoxide dismutase signature 2. GNAGsRlACgvI
ChainResidueDetails
AGLY136-ILE147

site_idPS00430
Number of Residues32
DetailsTONB_DEPENDENT_REC_1 TonB-dependent receptor (TBDR) proteins signature 1. atkavcvlkgdgpvqgtihfeakg...........................................................................................DTVVVTGS
ChainResidueDetails
AALA1-SER32

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues48
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"1055410","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12906825","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues64
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"1055410","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues16
DetailsModified residue: {"description":"N-acetylalanine","evidences":[{"source":"PubMed","id":"4279916","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

site_idSWS_FT_FI4
Number of Residues48
DetailsModified residue: {"description":"N6-succinyllysine","evidences":[{"source":"UniProtKB","id":"P08228","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI5
Number of Residues16
DetailsModified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P07632","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI6
Number of Residues16
DetailsModified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P08228","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI7
Number of Residues16
DetailsModified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"P00441","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI8
Number of Residues15
DetailsModified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"P08228","evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

site_idSWS_FT_FI9
Number of Residues16
DetailsLipidation: {"description":"S-palmitoyl cysteine","evidences":[{"evidenceCode":"ECO:0000250"}]}
ChainResidueDetails

247536

PDB entries from 2026-01-14

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