8IPS

Cryo-EM structure of heme transporter CydDC from Escherichia coli in the inward facing heme loading state

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0005524	molecular_function	ATP binding
A	0005886	cellular_component	plasma membrane
A	0006865	biological_process	amino acid transport
A	0015439	molecular_function	ABC-type heme transporter activity
A	0016020	cellular_component	membrane
A	0016887	molecular_function	ATP hydrolysis activity
A	0033228	biological_process	cysteine export across plasma membrane
A	0034775	biological_process	glutathione transmembrane transport
A	0035351	biological_process	heme transmembrane transport
A	0042626	molecular_function	ATPase-coupled transmembrane transporter activity
A	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
A	0045454	biological_process	cell redox homeostasis
A	0055051	cellular_component	ATP-binding cassette (ABC) transporter complex, integrated substrate binding
A	0055085	biological_process	transmembrane transport
A	0140359	molecular_function	ABC-type transporter activity
A	1903605	biological_process	cytochrome biosynthetic process
B	0000166	molecular_function	nucleotide binding
B	0005524	molecular_function	ATP binding
B	0005886	cellular_component	plasma membrane
B	0006865	biological_process	amino acid transport
B	0006869	biological_process	lipid transport
B	0015439	molecular_function	ABC-type heme transporter activity
B	0016020	cellular_component	membrane
B	0016887	molecular_function	ATP hydrolysis activity
B	0033228	biological_process	cysteine export across plasma membrane
B	0034040	molecular_function	ATPase-coupled lipid transmembrane transporter activity
B	0034775	biological_process	glutathione transmembrane transport
B	0035351	biological_process	heme transmembrane transport
B	0042883	biological_process	cysteine transport
B	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
B	0045454	biological_process	cell redox homeostasis
B	0055051	cellular_component	ATP-binding cassette (ABC) transporter complex, integrated substrate binding
B	0055085	biological_process	transmembrane transport
B	0140359	molecular_function	ABC-type transporter activity
B	1903605	biological_process	cytochrome biosynthetic process

Functional Information from PROSITE/UniProt

site_id	PS00211
Number of Residues	15
Details	ABC_TRANSPORTER_1 ABC transporters family signature. LSGGELRRLAIARAL

Chain	Residue	Details
A	LEU475-LEU489
B	LEU486-LEU500

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	866
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"15470119","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	240
Details	Transmembrane: {"description":"Helical","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	16
Details	Topological domain: {"description":"Periplasmic","evidences":[{"source":"PubMed","id":"15470119","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	572
Details	Domain: {"description":"ABC transmembrane type-1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00441","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	466
Details	Domain: {"description":"ABC transporter","evidences":[{"source":"PROSITE-ProRule","id":"PRU00434","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI6
Number of Residues	14
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00434","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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