Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

8IOG

Cryo-EM structure of porcine bc1 complex in isolated state

Functional Information from GO Data

Chain	GOid	namespace	contents
a	0005739	cellular_component	mitochondrion
a	0005743	cellular_component	mitochondrial inner membrane
a	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
a	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
a	0009055	molecular_function	electron transfer activity
a	0016020	cellular_component	membrane
a	0016491	molecular_function	oxidoreductase activity
a	0022904	biological_process	respiratory electron transport chain
a	0045275	cellular_component	respiratory chain complex III
a	0046872	molecular_function	metal ion binding
a	1902600	biological_process	proton transmembrane transport
A	0005739	cellular_component	mitochondrion
A	0005743	cellular_component	mitochondrial inner membrane
A	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
A	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
A	0009055	molecular_function	electron transfer activity
A	0016020	cellular_component	membrane
A	0016491	molecular_function	oxidoreductase activity
A	0022904	biological_process	respiratory electron transport chain
A	0045275	cellular_component	respiratory chain complex III
A	0046872	molecular_function	metal ion binding
A	1902600	biological_process	proton transmembrane transport
b	0005739	cellular_component	mitochondrion
b	0005743	cellular_component	mitochondrial inner membrane
b	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
b	0009055	molecular_function	electron transfer activity
b	0020037	molecular_function	heme binding
b	0045275	cellular_component	respiratory chain complex III
b	0046872	molecular_function	metal ion binding
B	0005739	cellular_component	mitochondrion
B	0005743	cellular_component	mitochondrial inner membrane
B	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
B	0009055	molecular_function	electron transfer activity
B	0020037	molecular_function	heme binding
B	0045275	cellular_component	respiratory chain complex III
B	0046872	molecular_function	metal ion binding
c	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
c	0016020	cellular_component	membrane
c	0051537	molecular_function	2 iron, 2 sulfur cluster binding
C	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
C	0016020	cellular_component	membrane
C	0051537	molecular_function	2 iron, 2 sulfur cluster binding
d	0046872	molecular_function	metal ion binding
D	0046872	molecular_function	metal ion binding
e	0004222	molecular_function	metalloendopeptidase activity
e	0005654	cellular_component	nucleoplasm
e	0005739	cellular_component	mitochondrion
e	0005743	cellular_component	mitochondrial inner membrane
e	0006508	biological_process	proteolysis
e	0045275	cellular_component	respiratory chain complex III
e	0046872	molecular_function	metal ion binding
E	0004222	molecular_function	metalloendopeptidase activity
E	0005654	cellular_component	nucleoplasm
E	0005739	cellular_component	mitochondrion
E	0005743	cellular_component	mitochondrial inner membrane
E	0006508	biological_process	proteolysis
E	0045275	cellular_component	respiratory chain complex III
E	0046872	molecular_function	metal ion binding
f	0005739	cellular_component	mitochondrion
f	0005743	cellular_component	mitochondrial inner membrane
f	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
f	0045275	cellular_component	respiratory chain complex III
F	0005739	cellular_component	mitochondrion
F	0005743	cellular_component	mitochondrial inner membrane
F	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
F	0045275	cellular_component	respiratory chain complex III
g	0005739	cellular_component	mitochondrion
g	0005743	cellular_component	mitochondrial inner membrane
g	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
g	0045275	cellular_component	respiratory chain complex III
G	0005739	cellular_component	mitochondrion
G	0005743	cellular_component	mitochondrial inner membrane
G	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
G	0045275	cellular_component	respiratory chain complex III
h	0005739	cellular_component	mitochondrion
h	0005743	cellular_component	mitochondrial inner membrane
h	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
h	0021539	biological_process	subthalamus development
h	0021548	biological_process	pons development
h	0021680	biological_process	cerebellar Purkinje cell layer development
h	0021766	biological_process	hippocampus development
h	0021794	biological_process	thalamus development
h	0021854	biological_process	hypothalamus development
h	0021860	biological_process	pyramidal neuron development
h	0030901	biological_process	midbrain development
h	0045275	cellular_component	respiratory chain complex III
H	0005739	cellular_component	mitochondrion
H	0005743	cellular_component	mitochondrial inner membrane
H	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
H	0021539	biological_process	subthalamus development
H	0021548	biological_process	pons development
H	0021680	biological_process	cerebellar Purkinje cell layer development
H	0021766	biological_process	hippocampus development
H	0021794	biological_process	thalamus development
H	0021854	biological_process	hypothalamus development
H	0021860	biological_process	pyramidal neuron development
H	0030901	biological_process	midbrain development
H	0045275	cellular_component	respiratory chain complex III
i	0005739	cellular_component	mitochondrion
i	0005743	cellular_component	mitochondrial inner membrane
i	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
i	0016020	cellular_component	membrane
i	0045275	cellular_component	respiratory chain complex III
I	0005739	cellular_component	mitochondrion
I	0005743	cellular_component	mitochondrial inner membrane
I	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
I	0016020	cellular_component	membrane
I	0045275	cellular_component	respiratory chain complex III
j	0005739	cellular_component	mitochondrion
j	0005743	cellular_component	mitochondrial inner membrane
j	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
j	0016020	cellular_component	membrane
J	0005739	cellular_component	mitochondrion
J	0005743	cellular_component	mitochondrial inner membrane
J	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
J	0016020	cellular_component	membrane
k	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity
K	0008121	molecular_function	ubiquinol-cytochrome-c reductase activity

Functional Information from PROSITE/UniProt

site_id	PS00143
Number of Residues	24
Details	INSULINASE Insulinase family, zinc-binding region signature. GsryedsnnlGtSHLLRLAsSlTT

Chain	Residue	Details
E	GLY68-THR91

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	322
Details	TRANSMEM: Helical => ECO:0000250\|UniProtKB:P00157

Chain	Residue	Details
A	PHE33-MET53
a	TRP77-VAL98
a	TRP113-LEU133
a	PHE178-LEU198
a	ILE226-SER246
a	LEU288-HIS308
a	LEU320-GLY340
a	PHE347-PRO367
A	TRP77-VAL98
A	TRP113-LEU133
A	PHE178-LEU198
A	ILE226-SER246
A	LEU288-HIS308
A	LEU320-GLY340
A	PHE347-PRO367
a	PHE33-MET53

site_id	SWS_FT_FI2
Number of Residues	2
Details	BINDING: axial binding residue => ECO:0000255\|PROSITE-ProRule:PRU00968

Chain	Residue	Details
A	HIS83
a	HIS83

site_id	SWS_FT_FI3
Number of Residues	6
Details	BINDING: axial binding residue => ECO:0000250\|UniProtKB:P00157

Chain	Residue	Details
A	HIS97
A	HIS182
A	HIS196
a	HIS97
a	HIS182
a	HIS196

site_id	SWS_FT_FI4
Number of Residues	2
Details	BINDING: BINDING => ECO:0000250\|UniProtKB:P00157

Chain	Residue	Details
A	HIS201
a	HIS201

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)