Loading
PDBj
English日本語简体中文繁體中文한국어
✖
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help
SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

8IJ5

Cryo-EM structure of Integrin AVB3

Functional Information from GO Data
ChainGOidnamespacecontents
E0007155biological_processcell adhesion
E0008305cellular_componentintegrin complex
Functional Information from PROSITE/UniProt
site_idPS00022
Number of Residues12
DetailsEGF_1 EGF-like domain signature 1. CrCgpGwlGSqC
ChainResidueDetails
BCYS486-CYS497
site_idPS01186
Number of Residues12
DetailsEGF_2 EGF-like domain signature 2. CrCgpGWlgsq....C
ChainResidueDetails
BCYS486-CYS497
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues7
DetailsRegion: {"description":"Involved in CX3CL1-, NRG1-, FGF1- and IGF1-binding","evidences":[{"source":"PubMed","id":"18441324","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19578119","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20682778","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"23125415","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails
site_idSWS_FT_FI2
Number of Residues20
DetailsRegion: {"description":"CX3CL1-binding","evidences":[{"source":"PubMed","id":"24789099","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails
site_idSWS_FT_FI3
Number of Residues1
DetailsBinding site: {"description":"in MIDAS binding site","evidences":[{"source":"PubMed","id":"15378069","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19111664","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1TYE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3FCU","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI4
Number of Residues2
DetailsBinding site: {"description":"in ADMIDAS binding site","evidences":[{"source":"PubMed","id":"11546839","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15378069","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19111664","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19704023","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1JV2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1TYE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3FCS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3FCU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3IJE","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI5
Number of Residues4
DetailsBinding site: {"description":"in LIMBS binding site","evidences":[{"source":"PubMed","id":"15378069","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19111664","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1TYE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3FCS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3FCU","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI6
Number of Residues1
DetailsBinding site: {"description":"in MIDAS binding site","evidences":[{"source":"PubMed","id":"15378069","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19111664","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1TYE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3FCS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3FCU","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI7
Number of Residues1
DetailsBinding site: {"description":"in LIMBS binding site","evidences":[{"source":"PDB","id":"4G1M","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI8
Number of Residues1
DetailsBinding site: {"description":"in ADMIDAS binding site and unliganded-closed conformation","evidences":[{"source":"PubMed","id":"11546839","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19111664","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19704023","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1JV2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3FCS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3IJE","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI9
Number of Residues1
DetailsGlycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"15378069","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16263699","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"16335952","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19111664","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19704023","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1TYE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3IJE","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI10
Number of Residues2
DetailsGlycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"11546839","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"15378069","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19111664","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19704023","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1JV2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1TYE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3IJE","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI11
Number of Residues66
DetailsRepeat: {"description":"FG-GAP 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00803","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI12
Number of Residues61
DetailsRepeat: {"description":"FG-GAP 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00803","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI13
Number of Residues52
DetailsRepeat: {"description":"FG-GAP 3","evidences":[{"source":"PROSITE-ProRule","id":"PRU00803","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI14
Number of Residues54
DetailsRepeat: {"description":"FG-GAP 4","evidences":[{"source":"PROSITE-ProRule","id":"PRU00803","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI15
Number of Residues65
DetailsRepeat: {"description":"FG-GAP 5","evidences":[{"source":"PROSITE-ProRule","id":"PRU00803","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI16
Number of Residues57
DetailsRepeat: {"description":"FG-GAP 6","evidences":[{"source":"PROSITE-ProRule","id":"PRU00803","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI17
Number of Residues20
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"19704023","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28117447","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3IJE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FFG","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI18
Number of Residues1
DetailsGlycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19349973","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19704023","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28117447","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3IJE","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI19
Number of Residues2
DetailsGlycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"19704023","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28117447","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3IJE","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI20
Number of Residues1
DetailsGlycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"12754519","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19704023","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"28117447","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3IJE","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails

247536

PDB entries from 2026-01-14

PDB statisticsPDBj update infoContact PDBjnumon