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8IC2

Respiratory complex CI:CIII2, type I, PERK -/- mouse under cold temperature

This is a non-PDB format compatible entry.
Functional Information from GO Data
ChainGOidnamespacecontents
a0005739cellular_componentmitochondrion
a0005743cellular_componentmitochondrial inner membrane
a0009060biological_processaerobic respiration
a0016020cellular_componentmembrane
a0031966cellular_componentmitochondrial membrane
a0042776biological_processproton motive force-driven mitochondrial ATP synthesis
a0045271cellular_componentrespiratory chain complex I
A0005739cellular_componentmitochondrion
A0005743cellular_componentmitochondrial inner membrane
A0006120biological_processmitochondrial electron transport, NADH to ubiquinone
A0006979biological_processresponse to oxidative stress
A0008137molecular_functionNADH dehydrogenase (ubiquinone) activity
A0009060biological_processaerobic respiration
A0009642biological_processresponse to light intensity
A0009725biological_processresponse to hormone
A0016020cellular_componentmembrane
A0042776biological_processproton motive force-driven mitochondrial ATP synthesis
A0045271cellular_componentrespiratory chain complex I
A0071385biological_processcellular response to glucocorticoid stimulus
A1902600biological_processproton transmembrane transport
Aa0005515molecular_functionprotein binding
Aa0005739cellular_componentmitochondrion
Aa0005743cellular_componentmitochondrial inner membrane
Aa0006122biological_processmitochondrial electron transport, ubiquinol to cytochrome c
Aa0014823biological_processresponse to activity
Aa0016020cellular_componentmembrane
Aa0031625molecular_functionubiquitin protein ligase binding
Aa0034551biological_processmitochondrial respiratory chain complex III assembly
Aa0043209cellular_componentmyelin sheath
Aa0043279biological_processresponse to alkaloid
Aa0044877molecular_functionprotein-containing complex binding
Aa0045275cellular_componentrespiratory chain complex III
Aa0045333biological_processcellular respiration
Aa0046872molecular_functionmetal ion binding
AA0005515molecular_functionprotein binding
AA0005739cellular_componentmitochondrion
AA0005743cellular_componentmitochondrial inner membrane
AA0006122biological_processmitochondrial electron transport, ubiquinol to cytochrome c
AA0014823biological_processresponse to activity
AA0016020cellular_componentmembrane
AA0031625molecular_functionubiquitin protein ligase binding
AA0034551biological_processmitochondrial respiratory chain complex III assembly
AA0043209cellular_componentmyelin sheath
AA0043279biological_processresponse to alkaloid
AA0044877molecular_functionprotein-containing complex binding
AA0045275cellular_componentrespiratory chain complex III
AA0045333biological_processcellular respiration
AA0046872molecular_functionmetal ion binding
Ab0004222molecular_functionmetalloendopeptidase activity
Ab0005515molecular_functionprotein binding
Ab0005654cellular_componentnucleoplasm
Ab0005739cellular_componentmitochondrion
Ab0005743cellular_componentmitochondrial inner membrane
Ab0006122biological_processmitochondrial electron transport, ubiquinol to cytochrome c
Ab0006508biological_processproteolysis
Ab0009410biological_processresponse to xenobiotic stimulus
Ab0016020cellular_componentmembrane
Ab0043209cellular_componentmyelin sheath
Ab0044877molecular_functionprotein-containing complex binding
Ab0045275cellular_componentrespiratory chain complex III
Ab0045333biological_processcellular respiration
Ab0046872molecular_functionmetal ion binding
AB0004222molecular_functionmetalloendopeptidase activity
AB0005515molecular_functionprotein binding
AB0005654cellular_componentnucleoplasm
AB0005739cellular_componentmitochondrion
AB0005743cellular_componentmitochondrial inner membrane
AB0006122biological_processmitochondrial electron transport, ubiquinol to cytochrome c
AB0006508biological_processproteolysis
AB0009410biological_processresponse to xenobiotic stimulus
AB0016020cellular_componentmembrane
AB0043209cellular_componentmyelin sheath
AB0044877molecular_functionprotein-containing complex binding
AB0045275cellular_componentrespiratory chain complex III
AB0045333biological_processcellular respiration
AB0046872molecular_functionmetal ion binding
Ac0001666biological_processresponse to hypoxia
Ac0005739cellular_componentmitochondrion
Ac0005743cellular_componentmitochondrial inner membrane
Ac0006122biological_processmitochondrial electron transport, ubiquinol to cytochrome c
Ac0007584biological_processresponse to nutrient
Ac0008121molecular_functionquinol-cytochrome-c reductase activity
Ac0009055molecular_functionelectron transfer activity
Ac0009410biological_processresponse to xenobiotic stimulus
Ac0009636biological_processresponse to toxic substance
Ac0009725biological_processresponse to hormone
Ac0015990biological_processelectron transport coupled proton transport
Ac0016020cellular_componentmembrane
Ac0016491molecular_functionoxidoreductase activity
Ac0022904biological_processrespiratory electron transport chain
Ac0031100biological_processanimal organ regeneration
Ac0032991cellular_componentprotein-containing complex
Ac0033590biological_processresponse to cobalamin
Ac0033762biological_processresponse to glucagon
Ac0044877molecular_functionprotein-containing complex binding
Ac0045275cellular_componentrespiratory chain complex III
Ac0045333biological_processcellular respiration
Ac0045471biological_processresponse to ethanol
Ac0046686biological_processresponse to cadmium ion
Ac0046688biological_processresponse to copper ion
Ac0046689biological_processresponse to mercury ion
Ac0046872molecular_functionmetal ion binding
Ac0051592biological_processresponse to calcium ion
Ac0055093biological_processresponse to hyperoxia
Ac1904421biological_processresponse to D-galactosamine
AC0001666biological_processresponse to hypoxia
AC0005739cellular_componentmitochondrion
AC0005743cellular_componentmitochondrial inner membrane
AC0006122biological_processmitochondrial electron transport, ubiquinol to cytochrome c
AC0007584biological_processresponse to nutrient
AC0008121molecular_functionquinol-cytochrome-c reductase activity
AC0009055molecular_functionelectron transfer activity
AC0009410biological_processresponse to xenobiotic stimulus
AC0009636biological_processresponse to toxic substance
AC0009725biological_processresponse to hormone
AC0015990biological_processelectron transport coupled proton transport
AC0016020cellular_componentmembrane
AC0016491molecular_functionoxidoreductase activity
AC0022904biological_processrespiratory electron transport chain
AC0031100biological_processanimal organ regeneration
AC0032991cellular_componentprotein-containing complex
AC0033590biological_processresponse to cobalamin
AC0033762biological_processresponse to glucagon
AC0044877molecular_functionprotein-containing complex binding
AC0045275cellular_componentrespiratory chain complex III
AC0045333biological_processcellular respiration
AC0045471biological_processresponse to ethanol
AC0046686biological_processresponse to cadmium ion
AC0046688biological_processresponse to copper ion
AC0046689biological_processresponse to mercury ion
AC0046872molecular_functionmetal ion binding
AC0051592biological_processresponse to calcium ion
AC0055093biological_processresponse to hyperoxia
AC1904421biological_processresponse to D-galactosamine
Ad0005515molecular_functionprotein binding
Ad0005739cellular_componentmitochondrion
Ad0005743cellular_componentmitochondrial inner membrane
Ad0006122biological_processmitochondrial electron transport, ubiquinol to cytochrome c
Ad0008121molecular_functionquinol-cytochrome-c reductase activity
Ad0009055molecular_functionelectron transfer activity
Ad0016020cellular_componentmembrane
Ad0020037molecular_functionheme binding
Ad0033762biological_processresponse to glucagon
Ad0045275cellular_componentrespiratory chain complex III
Ad0045333biological_processcellular respiration
Ad0046872molecular_functionmetal ion binding
Ad1902600biological_processproton transmembrane transport
AD0005515molecular_functionprotein binding
AD0005739cellular_componentmitochondrion
AD0005743cellular_componentmitochondrial inner membrane
AD0006122biological_processmitochondrial electron transport, ubiquinol to cytochrome c
AD0008121molecular_functionquinol-cytochrome-c reductase activity
AD0009055molecular_functionelectron transfer activity
AD0016020cellular_componentmembrane
AD0020037molecular_functionheme binding
AD0033762biological_processresponse to glucagon
AD0045275cellular_componentrespiratory chain complex III
AD0045333biological_processcellular respiration
AD0046872molecular_functionmetal ion binding
AD1902600biological_processproton transmembrane transport
Ae0005515molecular_functionprotein binding
Ae0005739cellular_componentmitochondrion
Ae0005743cellular_componentmitochondrial inner membrane
Ae0006122biological_processmitochondrial electron transport, ubiquinol to cytochrome c
Ae0008121molecular_functionquinol-cytochrome-c reductase activity
Ae0009410biological_processresponse to xenobiotic stimulus
Ae0009725biological_processresponse to hormone
Ae0016020cellular_componentmembrane
Ae0016491molecular_functionoxidoreductase activity
Ae0022904biological_processrespiratory electron transport chain
Ae0031966cellular_componentmitochondrial membrane
Ae0043209cellular_componentmyelin sheath
Ae0044877molecular_functionprotein-containing complex binding
Ae0045275cellular_componentrespiratory chain complex III
Ae0046872molecular_functionmetal ion binding
Ae0051536molecular_functioniron-sulfur cluster binding
Ae0051537molecular_function2 iron, 2 sulfur cluster binding
Ae1902600biological_processproton transmembrane transport
AE0005515molecular_functionprotein binding
AE0005739cellular_componentmitochondrion
AE0005743cellular_componentmitochondrial inner membrane
AE0006122biological_processmitochondrial electron transport, ubiquinol to cytochrome c
AE0008121molecular_functionquinol-cytochrome-c reductase activity
AE0009410biological_processresponse to xenobiotic stimulus
AE0009725biological_processresponse to hormone
AE0016020cellular_componentmembrane
AE0016491molecular_functionoxidoreductase activity
AE0022904biological_processrespiratory electron transport chain
AE0031966cellular_componentmitochondrial membrane
AE0043209cellular_componentmyelin sheath
AE0044877molecular_functionprotein-containing complex binding
AE0045275cellular_componentrespiratory chain complex III
AE0046872molecular_functionmetal ion binding
AE0051536molecular_functioniron-sulfur cluster binding
AE0051537molecular_function2 iron, 2 sulfur cluster binding
AE1902600biological_processproton transmembrane transport
Af0005739cellular_componentmitochondrion
Af0005743cellular_componentmitochondrial inner membrane
Af0006122biological_processmitochondrial electron transport, ubiquinol to cytochrome c
Af0016020cellular_componentmembrane
Af0044877molecular_functionprotein-containing complex binding
Af0045275cellular_componentrespiratory chain complex III
AF0005739cellular_componentmitochondrion
AF0005743cellular_componentmitochondrial inner membrane
AF0006122biological_processmitochondrial electron transport, ubiquinol to cytochrome c
AF0016020cellular_componentmembrane
AF0044877molecular_functionprotein-containing complex binding
AF0045275cellular_componentrespiratory chain complex III
Ag0005515molecular_functionprotein binding
Ag0005739cellular_componentmitochondrion
Ag0005743cellular_componentmitochondrial inner membrane
Ag0006122biological_processmitochondrial electron transport, ubiquinol to cytochrome c
Ag0016020cellular_componentmembrane
Ag0021539biological_processsubthalamus development
Ag0021548biological_processpons development
Ag0021680biological_processcerebellar Purkinje cell layer development
Ag0021766biological_processhippocampus development
Ag0021794biological_processthalamus development
Ag0021854biological_processhypothalamus development
Ag0021860biological_processpyramidal neuron development
Ag0030901biological_processmidbrain development
Ag0045275cellular_componentrespiratory chain complex III
Ag0045333biological_processcellular respiration
AG0005515molecular_functionprotein binding
AG0005739cellular_componentmitochondrion
AG0005743cellular_componentmitochondrial inner membrane
AG0006122biological_processmitochondrial electron transport, ubiquinol to cytochrome c
AG0016020cellular_componentmembrane
AG0021539biological_processsubthalamus development
AG0021548biological_processpons development
AG0021680biological_processcerebellar Purkinje cell layer development
AG0021766biological_processhippocampus development
AG0021794biological_processthalamus development
AG0021854biological_processhypothalamus development
AG0021860biological_processpyramidal neuron development
AG0030901biological_processmidbrain development
AG0045275cellular_componentrespiratory chain complex III
AG0045333biological_processcellular respiration
Ah0005739cellular_componentmitochondrion
Ah0005743cellular_componentmitochondrial inner membrane
Ah0006122biological_processmitochondrial electron transport, ubiquinol to cytochrome c
Ah0008121molecular_functionquinol-cytochrome-c reductase activity
Ah0016020cellular_componentmembrane
Ah0045275cellular_componentrespiratory chain complex III
Ah0045333biological_processcellular respiration
Ah1902600biological_processproton transmembrane transport
AH0005739cellular_componentmitochondrion
AH0005743cellular_componentmitochondrial inner membrane
AH0006122biological_processmitochondrial electron transport, ubiquinol to cytochrome c
AH0008121molecular_functionquinol-cytochrome-c reductase activity
AH0016020cellular_componentmembrane
AH0045275cellular_componentrespiratory chain complex III
AH0045333biological_processcellular respiration
AH1902600biological_processproton transmembrane transport
AI0005515molecular_functionprotein binding
AI0005739cellular_componentmitochondrion
AI0005743cellular_componentmitochondrial inner membrane
AI0006122biological_processmitochondrial electron transport, ubiquinol to cytochrome c
AI0008121molecular_functionquinol-cytochrome-c reductase activity
AI0009410biological_processresponse to xenobiotic stimulus
AI0009725biological_processresponse to hormone
AI0016020cellular_componentmembrane
AI0016491molecular_functionoxidoreductase activity
AI0022904biological_processrespiratory electron transport chain
AI0031966cellular_componentmitochondrial membrane
AI0043209cellular_componentmyelin sheath
AI0044877molecular_functionprotein-containing complex binding
AI0045275cellular_componentrespiratory chain complex III
AI0046872molecular_functionmetal ion binding
AI0051536molecular_functioniron-sulfur cluster binding
AI0051537molecular_function2 iron, 2 sulfur cluster binding
AI1902600biological_processproton transmembrane transport
Aj0005739cellular_componentmitochondrion
Aj0005743cellular_componentmitochondrial inner membrane
Aj0006122biological_processmitochondrial electron transport, ubiquinol to cytochrome c
Aj0016020cellular_componentmembrane
Aj0045275cellular_componentrespiratory chain complex III
Aj0045333biological_processcellular respiration
AJ0005739cellular_componentmitochondrion
AJ0005743cellular_componentmitochondrial inner membrane
AJ0006122biological_processmitochondrial electron transport, ubiquinol to cytochrome c
AJ0016020cellular_componentmembrane
AJ0045275cellular_componentrespiratory chain complex III
AJ0045333biological_processcellular respiration
Ak0005739cellular_componentmitochondrion
Ak0005743cellular_componentmitochondrial inner membrane
Ak0006122biological_processmitochondrial electron transport, ubiquinol to cytochrome c
Ak0016020cellular_componentmembrane
Ak0045275cellular_componentrespiratory chain complex III
Ak0045333biological_processcellular respiration
AK0005739cellular_componentmitochondrion
AK0005743cellular_componentmitochondrial inner membrane
AK0006122biological_processmitochondrial electron transport, ubiquinol to cytochrome c
AK0016020cellular_componentmembrane
AK0045275cellular_componentrespiratory chain complex III
AK0045333biological_processcellular respiration
b0003674molecular_functionmolecular_function
b0005739cellular_componentmitochondrion
b0005743cellular_componentmitochondrial inner membrane
b0009060biological_processaerobic respiration
b0016020cellular_componentmembrane
b0042776biological_processproton motive force-driven mitochondrial ATP synthesis
b0045271cellular_componentrespiratory chain complex I
B0003954molecular_functionNADH dehydrogenase activity
B0004497molecular_functionmonooxygenase activity
B0005739cellular_componentmitochondrion
B0005743cellular_componentmitochondrial inner membrane
B0006120biological_processmitochondrial electron transport, NADH to ubiquinone
B0008137molecular_functionNADH dehydrogenase (ubiquinone) activity
B0009060biological_processaerobic respiration
B0015990biological_processelectron transport coupled proton transport
B0016020cellular_componentmembrane
B0016491molecular_functionoxidoreductase activity
B0032981biological_processmitochondrial respiratory chain complex I assembly
B0042776biological_processproton motive force-driven mitochondrial ATP synthesis
B0045271cellular_componentrespiratory chain complex I
B0046872molecular_functionmetal ion binding
B0048038molecular_functionquinone binding
B0051536molecular_functioniron-sulfur cluster binding
B0051539molecular_function4 iron, 4 sulfur cluster binding
c0003674molecular_functionmolecular_function
c0005739cellular_componentmitochondrion
c0005743cellular_componentmitochondrial inner membrane
c0009060biological_processaerobic respiration
c0016020cellular_componentmembrane
c0042776biological_processproton motive force-driven mitochondrial ATP synthesis
c0045271cellular_componentrespiratory chain complex I
C0003954molecular_functionNADH dehydrogenase activity
C0005515molecular_functionprotein binding
C0005739cellular_componentmitochondrion
C0005743cellular_componentmitochondrial inner membrane
C0006120biological_processmitochondrial electron transport, NADH to ubiquinone
C0008137molecular_functionNADH dehydrogenase (ubiquinone) activity
C0009060biological_processaerobic respiration
C0016020cellular_componentmembrane
C0016491molecular_functionoxidoreductase activity
C0016604cellular_componentnuclear body
C0016651molecular_functionoxidoreductase activity, acting on NAD(P)H
C0031966cellular_componentmitochondrial membrane
C0032981biological_processmitochondrial respiratory chain complex I assembly
C0042776biological_processproton motive force-driven mitochondrial ATP synthesis
C0043209cellular_componentmyelin sheath
C0045271cellular_componentrespiratory chain complex I
C0072593biological_processreactive oxygen species metabolic process
C1902600biological_processproton transmembrane transport
d0005737cellular_componentcytoplasm
d0005739cellular_componentmitochondrion
d0005743cellular_componentmitochondrial inner membrane
d0006120biological_processmitochondrial electron transport, NADH to ubiquinone
d0009060biological_processaerobic respiration
d0010918biological_processpositive regulation of mitochondrial membrane potential
d0016020cellular_componentmembrane
d0032981biological_processmitochondrial respiratory chain complex I assembly
d0042776biological_processproton motive force-driven mitochondrial ATP synthesis
d0045271cellular_componentrespiratory chain complex I
d1901223biological_processnegative regulation of non-canonical NF-kappaB signal transduction
d1903427biological_processnegative regulation of reactive oxygen species biosynthetic process
d2001171biological_processpositive regulation of ATP biosynthetic process
D0003954molecular_functionNADH dehydrogenase activity
D0005515molecular_functionprotein binding
D0005739cellular_componentmitochondrion
D0005743cellular_componentmitochondrial inner membrane
D0006120biological_processmitochondrial electron transport, NADH to ubiquinone
D0008137molecular_functionNADH dehydrogenase (ubiquinone) activity
D0009060biological_processaerobic respiration
D0016020cellular_componentmembrane
D0016491molecular_functionoxidoreductase activity
D0016651molecular_functionoxidoreductase activity, acting on NAD(P)H
D0019826molecular_functionoxygen sensor activity
D0022008biological_processneurogenesis
D0031625molecular_functionubiquitin protein ligase binding
D0032981biological_processmitochondrial respiratory chain complex I assembly
D0042063biological_processgliogenesis
D0042775biological_processmitochondrial ATP synthesis coupled electron transport
D0042776biological_processproton motive force-driven mitochondrial ATP synthesis
D0045271cellular_componentrespiratory chain complex I
D0046872molecular_functionmetal ion binding
D0048038molecular_functionquinone binding
D0051287molecular_functionNAD binding
D0051536molecular_functioniron-sulfur cluster binding
D0051539molecular_function4 iron, 4 sulfur cluster binding
D0061351biological_processneural precursor cell proliferation
D0071453biological_processcellular response to oxygen levels
D1902600biological_processproton transmembrane transport
e0003674molecular_functionmolecular_function
e0005739cellular_componentmitochondrion
e0005743cellular_componentmitochondrial inner membrane
e0005758cellular_componentmitochondrial intermembrane space
e0009060biological_processaerobic respiration
e0016020cellular_componentmembrane
e0032981biological_processmitochondrial respiratory chain complex I assembly
e0042776biological_processproton motive force-driven mitochondrial ATP synthesis
e0045271cellular_componentrespiratory chain complex I
E0003954molecular_functionNADH dehydrogenase activity
E0005739cellular_componentmitochondrion
E0005743cellular_componentmitochondrial inner membrane
E0006120biological_processmitochondrial electron transport, NADH to ubiquinone
E0007399biological_processnervous system development
E0008137molecular_functionNADH dehydrogenase (ubiquinone) activity
E0009060biological_processaerobic respiration
E0016020cellular_componentmembrane
E0016491molecular_functionoxidoreductase activity
E0042776biological_processproton motive force-driven mitochondrial ATP synthesis
E0043209cellular_componentmyelin sheath
E0045271cellular_componentrespiratory chain complex I
E0046872molecular_functionmetal ion binding
E0048738biological_processcardiac muscle tissue development
E0051536molecular_functioniron-sulfur cluster binding
E0051537molecular_function2 iron, 2 sulfur cluster binding
E1902600biological_processproton transmembrane transport
f0005739cellular_componentmitochondrion
f0005743cellular_componentmitochondrial inner membrane
f0009060biological_processaerobic respiration
f0016020cellular_componentmembrane
f0016607cellular_componentnuclear speck
f0042776biological_processproton motive force-driven mitochondrial ATP synthesis
f0045271cellular_componentrespiratory chain complex I
F0005515molecular_functionprotein binding
F0005739cellular_componentmitochondrion
F0005743cellular_componentmitochondrial inner membrane
F0006120biological_processmitochondrial electron transport, NADH to ubiquinone
F0008137molecular_functionNADH dehydrogenase (ubiquinone) activity
F0009060biological_processaerobic respiration
F0010181molecular_functionFMN binding
F0016020cellular_componentmembrane
F0016491molecular_functionoxidoreductase activity
F0042775biological_processmitochondrial ATP synthesis coupled electron transport
F0042776biological_processproton motive force-driven mitochondrial ATP synthesis
F0045271cellular_componentrespiratory chain complex I
F0046872molecular_functionmetal ion binding
F0051287molecular_functionNAD binding
F0051536molecular_functioniron-sulfur cluster binding
F0051539molecular_function4 iron, 4 sulfur cluster binding
F1902600biological_processproton transmembrane transport
g0003674molecular_functionmolecular_function
g0005739cellular_componentmitochondrion
g0005743cellular_componentmitochondrial inner membrane
g0009060biological_processaerobic respiration
g0016020cellular_componentmembrane
g0042776biological_processproton motive force-driven mitochondrial ATP synthesis
g0045271cellular_componentrespiratory chain complex I
G0005515molecular_functionprotein binding
G0005739cellular_componentmitochondrion
G0005743cellular_componentmitochondrial inner membrane
G0005758cellular_componentmitochondrial intermembrane space
G0006120biological_processmitochondrial electron transport, NADH to ubiquinone
G0008137molecular_functionNADH dehydrogenase (ubiquinone) activity
G0009055molecular_functionelectron transfer activity
G0009060biological_processaerobic respiration
G0016020cellular_componentmembrane
G0016491molecular_functionoxidoreductase activity
G0016651molecular_functionoxidoreductase activity, acting on NAD(P)H
G0032981biological_processmitochondrial respiratory chain complex I assembly
G0042773biological_processATP synthesis coupled electron transport
G0042776biological_processproton motive force-driven mitochondrial ATP synthesis
G0043209cellular_componentmyelin sheath
G0045271cellular_componentrespiratory chain complex I
G0045333biological_processcellular respiration
G0046872molecular_functionmetal ion binding
G0051536molecular_functioniron-sulfur cluster binding
G0051537molecular_function2 iron, 2 sulfur cluster binding
G0051539molecular_function4 iron, 4 sulfur cluster binding
G1902600biological_processproton transmembrane transport
h0003674molecular_functionmolecular_function
h0005654cellular_componentnucleoplasm
h0005739cellular_componentmitochondrion
h0005743cellular_componentmitochondrial inner membrane
h0009060biological_processaerobic respiration
h0016020cellular_componentmembrane
h0042776biological_processproton motive force-driven mitochondrial ATP synthesis
h0045271cellular_componentrespiratory chain complex I
H0001666biological_processresponse to hypoxia
H0003954molecular_functionNADH dehydrogenase activity
H0005739cellular_componentmitochondrion
H0005743cellular_componentmitochondrial inner membrane
H0006120biological_processmitochondrial electron transport, NADH to ubiquinone
H0008137molecular_functionNADH dehydrogenase (ubiquinone) activity
H0009060biological_processaerobic respiration
H0009410biological_processresponse to xenobiotic stimulus
H0016020cellular_componentmembrane
H0030425cellular_componentdendrite
H0031966cellular_componentmitochondrial membrane
H0032981biological_processmitochondrial respiratory chain complex I assembly
H0033194biological_processresponse to hydroperoxide
H0042776biological_processproton motive force-driven mitochondrial ATP synthesis
H0043025cellular_componentneuronal cell body
H0045271cellular_componentrespiratory chain complex I
H1902600biological_processproton transmembrane transport
i0005654cellular_componentnucleoplasm
i0005739cellular_componentmitochondrion
i0005743cellular_componentmitochondrial inner membrane
i0006120biological_processmitochondrial electron transport, NADH to ubiquinone
i0009060biological_processaerobic respiration
i0016020cellular_componentmembrane
i0031966cellular_componentmitochondrial membrane
i0042775biological_processmitochondrial ATP synthesis coupled electron transport
i0042776biological_processproton motive force-driven mitochondrial ATP synthesis
i0045271cellular_componentrespiratory chain complex I
I0003954molecular_functionNADH dehydrogenase activity
I0005515molecular_functionprotein binding
I0005739cellular_componentmitochondrion
I0005743cellular_componentmitochondrial inner membrane
I0006120biological_processmitochondrial electron transport, NADH to ubiquinone
I0008137molecular_functionNADH dehydrogenase (ubiquinone) activity
I0009060biological_processaerobic respiration
I0016020cellular_componentmembrane
I0016491molecular_functionoxidoreductase activity
I0016651molecular_functionoxidoreductase activity, acting on NAD(P)H
I0032981biological_processmitochondrial respiratory chain complex I assembly
I0042776biological_processproton motive force-driven mitochondrial ATP synthesis
I0045271cellular_componentrespiratory chain complex I
I0046872molecular_functionmetal ion binding
I0051536molecular_functioniron-sulfur cluster binding
I0051539molecular_function4 iron, 4 sulfur cluster binding
I1902600biological_processproton transmembrane transport
j0003674molecular_functionmolecular_function
j0005739cellular_componentmitochondrion
j0005743cellular_componentmitochondrial inner membrane
j0009060biological_processaerobic respiration
j0016020cellular_componentmembrane
j0042776biological_processproton motive force-driven mitochondrial ATP synthesis
j0045271cellular_componentrespiratory chain complex I
J0005739cellular_componentmitochondrion
J0005743cellular_componentmitochondrial inner membrane
J0006120biological_processmitochondrial electron transport, NADH to ubiquinone
J0008137molecular_functionNADH dehydrogenase (ubiquinone) activity
J0009060biological_processaerobic respiration
J0016020cellular_componentmembrane
J0032981biological_processmitochondrial respiratory chain complex I assembly
J0035094biological_processresponse to nicotine
J0042220biological_processresponse to cocaine
J0042542biological_processresponse to hydrogen peroxide
J0042776biological_processproton motive force-driven mitochondrial ATP synthesis
J0045271cellular_componentrespiratory chain complex I
J1902600biological_processproton transmembrane transport
k0003674molecular_functionmolecular_function
k0005739cellular_componentmitochondrion
k0005743cellular_componentmitochondrial inner membrane
k0009060biological_processaerobic respiration
k0016020cellular_componentmembrane
k0022900biological_processelectron transport chain
k0042776biological_processproton motive force-driven mitochondrial ATP synthesis
k0045271cellular_componentrespiratory chain complex I
K0005739cellular_componentmitochondrion
K0005743cellular_componentmitochondrial inner membrane
K0008137molecular_functionNADH dehydrogenase (ubiquinone) activity
K0009060biological_processaerobic respiration
K0016020cellular_componentmembrane
K0016651molecular_functionoxidoreductase activity, acting on NAD(P)H
K0042773biological_processATP synthesis coupled electron transport
K0042776biological_processproton motive force-driven mitochondrial ATP synthesis
K0045271cellular_componentrespiratory chain complex I
K1902600biological_processproton transmembrane transport
l0003674molecular_functionmolecular_function
l0005739cellular_componentmitochondrion
l0005743cellular_componentmitochondrial inner membrane
l0006120biological_processmitochondrial electron transport, NADH to ubiquinone
l0009060biological_processaerobic respiration
l0016020cellular_componentmembrane
l0042776biological_processproton motive force-driven mitochondrial ATP synthesis
l0045271cellular_componentrespiratory chain complex I
L0005739cellular_componentmitochondrion
L0005743cellular_componentmitochondrial inner membrane
L0006120biological_processmitochondrial electron transport, NADH to ubiquinone
L0008137molecular_functionNADH dehydrogenase (ubiquinone) activity
L0009060biological_processaerobic respiration
L0015990biological_processelectron transport coupled proton transport
L0016020cellular_componentmembrane
L0032981biological_processmitochondrial respiratory chain complex I assembly
L0042773biological_processATP synthesis coupled electron transport
L0042776biological_processproton motive force-driven mitochondrial ATP synthesis
L0045271cellular_componentrespiratory chain complex I
m0003674molecular_functionmolecular_function
m0005654cellular_componentnucleoplasm
m0005739cellular_componentmitochondrion
m0005743cellular_componentmitochondrial inner membrane
m0009060biological_processaerobic respiration
m0016020cellular_componentmembrane
m0042776biological_processproton motive force-driven mitochondrial ATP synthesis
m0045271cellular_componentrespiratory chain complex I
M0001666biological_processresponse to hypoxia
M0001701biological_processin utero embryonic development
M0003954molecular_functionNADH dehydrogenase activity
M0005739cellular_componentmitochondrion
M0005743cellular_componentmitochondrial inner membrane
M0006120biological_processmitochondrial electron transport, NADH to ubiquinone
M0008137molecular_functionNADH dehydrogenase (ubiquinone) activity
M0009060biological_processaerobic respiration
M0015990biological_processelectron transport coupled proton transport
M0016020cellular_componentmembrane
M0021549biological_processcerebellum development
M0032981biological_processmitochondrial respiratory chain complex I assembly
M0035094biological_processresponse to nicotine
M0042773biological_processATP synthesis coupled electron transport
M0042776biological_processproton motive force-driven mitochondrial ATP synthesis
M0045271cellular_componentrespiratory chain complex I
M0045471biological_processresponse to ethanol
M0048039molecular_functionubiquinone binding
n0005739cellular_componentmitochondrion
n0005743cellular_componentmitochondrial inner membrane
n0006120biological_processmitochondrial electron transport, NADH to ubiquinone
n0009060biological_processaerobic respiration
n0016020cellular_componentmembrane
n0042776biological_processproton motive force-driven mitochondrial ATP synthesis
n0045271cellular_componentrespiratory chain complex I
N0005739cellular_componentmitochondrion
N0005743cellular_componentmitochondrial inner membrane
N0006120biological_processmitochondrial electron transport, NADH to ubiquinone
N0008137molecular_functionNADH dehydrogenase (ubiquinone) activity
N0009060biological_processaerobic respiration
N0016020cellular_componentmembrane
N0032981biological_processmitochondrial respiratory chain complex I assembly
N0042776biological_processproton motive force-driven mitochondrial ATP synthesis
N0045271cellular_componentrespiratory chain complex I
N0072593biological_processreactive oxygen species metabolic process
N1902600biological_processproton transmembrane transport
o0003674molecular_functionmolecular_function
o0005739cellular_componentmitochondrion
o0005743cellular_componentmitochondrial inner membrane
o0005758cellular_componentmitochondrial intermembrane space
o0008137molecular_functionNADH dehydrogenase (ubiquinone) activity
o0009060biological_processaerobic respiration
o0016020cellular_componentmembrane
o0042776biological_processproton motive force-driven mitochondrial ATP synthesis
o0045271cellular_componentrespiratory chain complex I
o1902600biological_processproton transmembrane transport
O0005737cellular_componentcytoplasm
O0005739cellular_componentmitochondrion
O0005743cellular_componentmitochondrial inner membrane
O0005759cellular_componentmitochondrial matrix
O0006120biological_processmitochondrial electron transport, NADH to ubiquinone
O0008137molecular_functionNADH dehydrogenase (ubiquinone) activity
O0009060biological_processaerobic respiration
O0042776biological_processproton motive force-driven mitochondrial ATP synthesis
O0043209cellular_componentmyelin sheath
O0045271cellular_componentrespiratory chain complex I
O1902600biological_processproton transmembrane transport
p0005739cellular_componentmitochondrion
p0005743cellular_componentmitochondrial inner membrane
p0009060biological_processaerobic respiration
p0016020cellular_componentmembrane
p0042776biological_processproton motive force-driven mitochondrial ATP synthesis
p0045271cellular_componentrespiratory chain complex I
P0003954molecular_functionNADH dehydrogenase activity
P0005515molecular_functionprotein binding
P0005739cellular_componentmitochondrion
P0005743cellular_componentmitochondrial inner membrane
P0005759cellular_componentmitochondrial matrix
P0006744biological_processubiquinone biosynthetic process
P0007623biological_processcircadian rhythm
P0009060biological_processaerobic respiration
P0031966cellular_componentmitochondrial membrane
P0042776biological_processproton motive force-driven mitochondrial ATP synthesis
P0044877molecular_functionprotein-containing complex binding
P0045271cellular_componentrespiratory chain complex I
q0003674molecular_functionmolecular_function
q0005739cellular_componentmitochondrion
q0005743cellular_componentmitochondrial inner membrane
q0009060biological_processaerobic respiration
q0016020cellular_componentmembrane
q0042775biological_processmitochondrial ATP synthesis coupled electron transport
q0042776biological_processproton motive force-driven mitochondrial ATP synthesis
q0045271cellular_componentrespiratory chain complex I
Q0003016biological_processrespiratory system process
Q0005739cellular_componentmitochondrion
Q0005743cellular_componentmitochondrial inner membrane
Q0006099biological_processtricarboxylic acid cycle
Q0006954biological_processinflammatory response
Q0007420biological_processbrain development
Q0007601biological_processvisual perception
Q0007605biological_processsensory perception of sound
Q0007628biological_processadult walking behavior
Q0008137molecular_functionNADH dehydrogenase (ubiquinone) activity
Q0009060biological_processaerobic respiration
Q0014876biological_processresponse to injury involved in regulation of muscle adaptation
Q0016020cellular_componentmembrane
Q0022900biological_processelectron transport chain
Q0022904biological_processrespiratory electron transport chain
Q0030534biological_processadult behavior
Q0032981biological_processmitochondrial respiratory chain complex I assembly
Q0036343biological_processpsychomotor behavior
Q0042417biological_processdopamine metabolic process
Q0042776biological_processproton motive force-driven mitochondrial ATP synthesis
Q0045087biological_processinnate immune response
Q0045271cellular_componentrespiratory chain complex I
Q0048666biological_processneuron development
Q0050890biological_processcognition
Q0051402biological_processneuron apoptotic process
Q0051881biological_processregulation of mitochondrial membrane potential
Q0071453biological_processcellular response to oxygen levels
Q0072593biological_processreactive oxygen species metabolic process
Q1902600biological_processproton transmembrane transport
r0005739cellular_componentmitochondrion
r0005743cellular_componentmitochondrial inner membrane
r0006120biological_processmitochondrial electron transport, NADH to ubiquinone
r0009060biological_processaerobic respiration
r0016020cellular_componentmembrane
r0042773biological_processATP synthesis coupled electron transport
r0042776biological_processproton motive force-driven mitochondrial ATP synthesis
r0045271cellular_componentrespiratory chain complex I
R0001822biological_processkidney development
R0003674molecular_functionmolecular_function
R0005739cellular_componentmitochondrion
R0005743cellular_componentmitochondrial inner membrane
R0006120biological_processmitochondrial electron transport, NADH to ubiquinone
R0006631biological_processfatty acid metabolic process
R0006936biological_processmuscle contraction
R0007005biological_processmitochondrion organization
R0009060biological_processaerobic respiration
R0010467biological_processgene expression
R0016020cellular_componentmembrane
R0017145biological_processstem cell division
R0022904biological_processrespiratory electron transport chain
R0030330biological_processDNA damage response, signal transduction by p53 class mediator
R0032981biological_processmitochondrial respiratory chain complex I assembly
R0035264biological_processmulticellular organism growth
R0042776biological_processproton motive force-driven mitochondrial ATP synthesis
R0045271cellular_componentrespiratory chain complex I
R0051881biological_processregulation of mitochondrial membrane potential
R0061458biological_processreproductive system development
R0072359biological_processcirculatory system development
R0072497biological_processmesenchymal stem cell differentiation
R0072593biological_processreactive oxygen species metabolic process
R0090398biological_processcellular senescence
R0097168biological_processmesenchymal stem cell proliferation
s0005739cellular_componentmitochondrion
s0005743cellular_componentmitochondrial inner membrane
s0009060biological_processaerobic respiration
s0016020cellular_componentmembrane
s0042775biological_processmitochondrial ATP synthesis coupled electron transport
s0042776biological_processproton motive force-driven mitochondrial ATP synthesis
s0045271cellular_componentrespiratory chain complex I
S0001835biological_processblastocyst hatching
S0005739cellular_componentmitochondrion
S0005743cellular_componentmitochondrial inner membrane
S0008137molecular_functionNADH dehydrogenase (ubiquinone) activity
S0009060biological_processaerobic respiration
S0016020cellular_componentmembrane
S0031966cellular_componentmitochondrial membrane
S0042776biological_processproton motive force-driven mitochondrial ATP synthesis
S0045271cellular_componentrespiratory chain complex I
S1902600biological_processproton transmembrane transport
T0000035molecular_functionacyl binding
T0000036molecular_functionacyl carrier activity
T0005198molecular_functionstructural molecule activity
T0005654cellular_componentnucleoplasm
T0005739cellular_componentmitochondrion
T0005743cellular_componentmitochondrial inner membrane
T0006629biological_processlipid metabolic process
T0006631biological_processfatty acid metabolic process
T0006633biological_processfatty acid biosynthetic process
T0009060biological_processaerobic respiration
T0016226biological_processiron-sulfur cluster assembly
T0031966cellular_componentmitochondrial membrane
T0042776biological_processproton motive force-driven mitochondrial ATP synthesis
T0044571biological_process[2Fe-2S] cluster assembly
T0045271cellular_componentrespiratory chain complex I
T0099128cellular_componentmitochondrial [2Fe-2S] assembly complex
T0140978molecular_functionmitochondrial large ribosomal subunit binding
T1990229cellular_componentiron-sulfur cluster assembly complex
U0000035molecular_functionacyl binding
U0000036molecular_functionacyl carrier activity
U0005198molecular_functionstructural molecule activity
U0005654cellular_componentnucleoplasm
U0005739cellular_componentmitochondrion
U0005743cellular_componentmitochondrial inner membrane
U0006629biological_processlipid metabolic process
U0006631biological_processfatty acid metabolic process
U0006633biological_processfatty acid biosynthetic process
U0009060biological_processaerobic respiration
U0016226biological_processiron-sulfur cluster assembly
U0031966cellular_componentmitochondrial membrane
U0042776biological_processproton motive force-driven mitochondrial ATP synthesis
U0044571biological_process[2Fe-2S] cluster assembly
U0045271cellular_componentrespiratory chain complex I
U0099128cellular_componentmitochondrial [2Fe-2S] assembly complex
U0140978molecular_functionmitochondrial large ribosomal subunit binding
U1990229cellular_componentiron-sulfur cluster assembly complex
V0005739cellular_componentmitochondrion
V0005743cellular_componentmitochondrial inner membrane
V0009060biological_processaerobic respiration
V0016020cellular_componentmembrane
V0022904biological_processrespiratory electron transport chain
V0032991cellular_componentprotein-containing complex
V0042776biological_processproton motive force-driven mitochondrial ATP synthesis
V0045271cellular_componentrespiratory chain complex I
W0003674molecular_functionmolecular_function
W0005739cellular_componentmitochondrion
W0005743cellular_componentmitochondrial inner membrane
W0009060biological_processaerobic respiration
W0016020cellular_componentmembrane
W0031966cellular_componentmitochondrial membrane
W0032981biological_processmitochondrial respiratory chain complex I assembly
W0042776biological_processproton motive force-driven mitochondrial ATP synthesis
W0045271cellular_componentrespiratory chain complex I
X0005739cellular_componentmitochondrion
X0005743cellular_componentmitochondrial inner membrane
X0005758cellular_componentmitochondrial intermembrane space
X0006120biological_processmitochondrial electron transport, NADH to ubiquinone
X0009060biological_processaerobic respiration
X0016020cellular_componentmembrane
X0042776biological_processproton motive force-driven mitochondrial ATP synthesis
X0044877molecular_functionprotein-containing complex binding
X0045271cellular_componentrespiratory chain complex I
Y0005739cellular_componentmitochondrion
Y0005743cellular_componentmitochondrial inner membrane
Y0006120biological_processmitochondrial electron transport, NADH to ubiquinone
Y0016020cellular_componentmembrane
Y0045271cellular_componentrespiratory chain complex I
Z0005524molecular_functionATP binding
Z0005634cellular_componentnucleus
Z0005654cellular_componentnucleoplasm
Z0005737cellular_componentcytoplasm
Z0005739cellular_componentmitochondrion
Z0005743cellular_componentmitochondrial inner membrane
Z0006915biological_processapoptotic process
Z0009060biological_processaerobic respiration
Z0016020cellular_componentmembrane
Z0031966cellular_componentmitochondrial membrane
Z0032981biological_processmitochondrial respiratory chain complex I assembly
Z0035458biological_processcellular response to interferon-beta
Z0042776biological_processproton motive force-driven mitochondrial ATP synthesis
Z0045039biological_processprotein insertion into mitochondrial inner membrane
Z0045271cellular_componentrespiratory chain complex I
Z0045732biological_processpositive regulation of protein catabolic process
Z0045892biological_processnegative regulation of DNA-templated transcription
Z0071300biological_processcellular response to retinoic acid
Z0097191biological_processextrinsic apoptotic signaling pathway
Z0098803cellular_componentrespiratory chain complex
Z1900119biological_processpositive regulation of execution phase of apoptosis
Functional Information from PROSITE/UniProt
site_idPS00012
Number of Residues16
DetailsPHOSPHOPANTETHEINE Phosphopantetheine attachment site. DLGLDSLDQVEIIMAM
ChainResidueDetails
TASP107-MET122

site_idPS00018
Number of Residues13
DetailsEF_HAND_1 EF-hand calcium-binding domain. DIDAEKLMCpqEI
ChainResidueDetails
TASP132-ILE144

site_idPS00143
Number of Residues24
DetailsINSULINASE Insulinase family, zinc-binding region signature. GsryedsnnlGtSHLLRLAsSlTT
ChainResidueDetails
AbGLY68-THR91

site_idPS00198
Number of Residues12
Details4FE4S_FER_1 4Fe-4S ferredoxin-type iron-sulfur binding region signature. CiACKlCEaICP
ChainResidueDetails
ICYS113-PRO124
ICYS152-PRO163

site_idPS00535
Number of Residues12
DetailsCOMPLEX1_49K Respiratory chain NADH dehydrogenase 49 Kd subunit signature. LHRGtEKLiEyK
ChainResidueDetails
DLEU116-LYS127

site_idPS00542
Number of Residues22
DetailsCOMPLEX1_30K Respiratory chain NADH dehydrogenase 30 Kd subunit signature. EREvwDMFgvfffnHpdlRrIL
ChainResidueDetails
CGLU166-LEU187

site_idPS00641
Number of Residues18
DetailsCOMPLEX1_75K_1 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 1. PrfCYherlsvaGnCRmC
ChainResidueDetails
GPRO61-CYS78

site_idPS00642
Number of Residues13
DetailsCOMPLEX1_75K_2 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2. CPiCDqGGeCdLQ
ChainResidueDetails
GCYS128-GLN140

site_idPS00643
Number of Residues11
DetailsCOMPLEX1_75K_3 Respiratory-chain NADH dehydrogenase 75 Kd subunit signature 3. RCIqCtRCIrF
ChainResidueDetails
GARG175-PHE185

site_idPS00644
Number of Residues16
DetailsCOMPLEX1_51K_1 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 1. GAGAYICGEETALIES
ChainResidueDetails
FGLY200-SER215

site_idPS00645
Number of Residues12
DetailsCOMPLEX1_51K_2 Respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2. ESCGqCtPCReG
ChainResidueDetails
FGLU377-GLY388

site_idPS00667
Number of Residues16
DetailsCOMPLEX1_ND1_1 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. GILQpFaDAMKLFmKE
ChainResidueDetails
HGLY44-GLU59

site_idPS00668
Number of Residues14
DetailsCOMPLEX1_ND1_2 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. PFDLTEGEseLVs.G
ChainResidueDetails
HPRO197-GLY210

site_idPS01099
Number of Residues19
DetailsCOMPLEX1_24K Respiratory-chain NADH dehydrogenase 24 Kd subunit signature. DklFTlieveCLGaCvnAP
ChainResidueDetails
EASP165-PRO183

site_idPS01150
Number of Residues17
DetailsCOMPLEX1_20K Respiratory-chain NADH dehydrogenase 20 Kd subunit signature. GcDRIVPVDIYvPgCPP
ChainResidueDetails
BGLY180-PRO196

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsMOD_RES: N-acetylalanine => ECO:0000250|UniProtKB:Q9Y6M9
ChainResidueDetails
nALA2
NLEU324-ILE344
MMET350-PRO370
MTHR392-ILE412
MLEU434-ILE454
LLEU457-ILE477
LMET482-LEU502
LLEU586-LEU606
ULYS88
NALA56-LEU76
NGLY92-TRP114
NLEU149-ASN171
NILE178-PRO198
NLEU200-MET220
NLEU241-LEU261
NASN274-THR294

site_idSWS_FT_FI2
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q9Y6M9
ChainResidueDetails
nSER85
VLYS60
GCYS131
GCYS137

site_idSWS_FT_FI3
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:21183079
ChainResidueDetails
mSER26
kHIS13
kHIS15
GLYS709
AcHIS182
AcHIS196

site_idSWS_FT_FI4
Number of Residues2
DetailsMOD_RES: N6-succinyllysine; alternate => ECO:0007744|PubMed:23806337
ChainResidueDetails
kLYS29
AISER241
AeCYS217
AeHIS219
AeCYS236
AeHIS239
AeSER241
kLYS40
AECYS236
AEHIS239
AESER241
AICYS217
AIHIS219
AICYS236
AIHIS239

site_idSWS_FT_FI5
Number of Residues1
DetailsMOD_RES: N6-succinyllysine; alternate => ECO:0007744|PubMed:23806337
ChainResidueDetails
VLYS98
AgLYS33
AdHIS125
AdMET244

237992

PDB entries from 2025-06-25

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