8IBC

Respiratory complex CIII2, focus-refined of type IB, Wild type mouse under cold temperature

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
AA	0005515	molecular_function	protein binding
AA	0005739	cellular_component	mitochondrion
AA	0005743	cellular_component	mitochondrial inner membrane
AA	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
AA	0006627	biological_process	protein processing involved in protein targeting to mitochondrion
AA	0014823	biological_process	response to activity
AA	0017087	cellular_component	mitochondrial processing peptidase complex
AA	0022904	biological_process	respiratory electron transport chain
AA	0031625	molecular_function	ubiquitin protein ligase binding
AA	0034551	biological_process	mitochondrial respiratory chain complex III assembly
AA	0043209	cellular_component	myelin sheath
AA	0043279	biological_process	response to alkaloid
AA	0044877	molecular_function	protein-containing complex binding
AA	0045275	cellular_component	respiratory chain complex III
AA	0045333	biological_process	cellular respiration
AA	0046872	molecular_function	metal ion binding
AB	0004222	molecular_function	metalloendopeptidase activity
AB	0005515	molecular_function	protein binding
AB	0005654	cellular_component	nucleoplasm
AB	0005739	cellular_component	mitochondrion
AB	0005743	cellular_component	mitochondrial inner membrane
AB	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
AB	0006508	biological_process	proteolysis
AB	0009410	biological_process	response to xenobiotic stimulus
AB	0022904	biological_process	respiratory electron transport chain
AB	0043209	cellular_component	myelin sheath
AB	0044877	molecular_function	protein-containing complex binding
AB	0045275	cellular_component	respiratory chain complex III
AB	0045333	biological_process	cellular respiration
AB	0046872	molecular_function	metal ion binding
AC	0001666	biological_process	response to hypoxia
AC	0005739	cellular_component	mitochondrion
AC	0005743	cellular_component	mitochondrial inner membrane
AC	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
AC	0007584	biological_process	response to nutrient
AC	0008121	molecular_function	quinol-cytochrome-c reductase activity
AC	0009055	molecular_function	electron transfer activity
AC	0009410	biological_process	response to xenobiotic stimulus
AC	0009636	biological_process	response to toxic substance
AC	0009725	biological_process	response to hormone
AC	0015990	biological_process	electron transport coupled proton transport
AC	0016020	cellular_component	membrane
AC	0016491	molecular_function	oxidoreductase activity
AC	0022904	biological_process	respiratory electron transport chain
AC	0031100	biological_process	animal organ regeneration
AC	0032991	cellular_component	protein-containing complex
AC	0033590	biological_process	response to cobalamin
AC	0033762	biological_process	response to glucagon
AC	0044877	molecular_function	protein-containing complex binding
AC	0045275	cellular_component	respiratory chain complex III
AC	0045333	biological_process	cellular respiration
AC	0045471	biological_process	response to ethanol
AC	0046686	biological_process	response to cadmium ion
AC	0046688	biological_process	response to copper ion
AC	0046689	biological_process	response to mercury ion
AC	0046872	molecular_function	metal ion binding
AC	0051592	biological_process	response to calcium ion
AC	0055093	biological_process	response to hyperoxia
AC	1904421	biological_process	response to D-galactosamine
AD	0005515	molecular_function	protein binding
AD	0005739	cellular_component	mitochondrion
AD	0005743	cellular_component	mitochondrial inner membrane
AD	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
AD	0008121	molecular_function	quinol-cytochrome-c reductase activity
AD	0009055	molecular_function	electron transfer activity
AD	0016020	cellular_component	membrane
AD	0020037	molecular_function	heme binding
AD	0022904	biological_process	respiratory electron transport chain
AD	0033762	biological_process	response to glucagon
AD	0045275	cellular_component	respiratory chain complex III
AD	0045333	biological_process	cellular respiration
AD	0046872	molecular_function	metal ion binding
AD	1902600	biological_process	proton transmembrane transport
AE	0005515	molecular_function	protein binding
AE	0005739	cellular_component	mitochondrion
AE	0005743	cellular_component	mitochondrial inner membrane
AE	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
AE	0008121	molecular_function	quinol-cytochrome-c reductase activity
AE	0009410	biological_process	response to xenobiotic stimulus
AE	0009725	biological_process	response to hormone
AE	0016020	cellular_component	membrane
AE	0016491	molecular_function	oxidoreductase activity
AE	0022904	biological_process	respiratory electron transport chain
AE	0031966	cellular_component	mitochondrial membrane
AE	0043209	cellular_component	myelin sheath
AE	0044877	molecular_function	protein-containing complex binding
AE	0045275	cellular_component	respiratory chain complex III
AE	0046872	molecular_function	metal ion binding
AE	0051536	molecular_function	iron-sulfur cluster binding
AE	0051537	molecular_function	2 iron, 2 sulfur cluster binding
AE	1902600	biological_process	proton transmembrane transport
AF	0005743	cellular_component	mitochondrial inner membrane
AF	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
AF	0016020	cellular_component	membrane
AF	0022904	biological_process	respiratory electron transport chain
AF	0044877	molecular_function	protein-containing complex binding
AF	0045275	cellular_component	respiratory chain complex III
AG	0005515	molecular_function	protein binding
AG	0005739	cellular_component	mitochondrion
AG	0005743	cellular_component	mitochondrial inner membrane
AG	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
AG	0016020	cellular_component	membrane
AG	0021539	biological_process	subthalamus development
AG	0021548	biological_process	pons development
AG	0021680	biological_process	cerebellar Purkinje cell layer development
AG	0021766	biological_process	hippocampus development
AG	0021794	biological_process	thalamus development
AG	0021854	biological_process	hypothalamus development
AG	0021860	biological_process	pyramidal neuron development
AG	0022904	biological_process	respiratory electron transport chain
AG	0030901	biological_process	midbrain development
AG	0045275	cellular_component	respiratory chain complex III
AG	0045333	biological_process	cellular respiration
AH	0005739	cellular_component	mitochondrion
AH	0005743	cellular_component	mitochondrial inner membrane
AH	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
AH	0008121	molecular_function	quinol-cytochrome-c reductase activity
AH	0022904	biological_process	respiratory electron transport chain
AH	0044877	molecular_function	protein-containing complex binding
AH	0045275	cellular_component	respiratory chain complex III
AH	0045333	biological_process	cellular respiration
AH	1902600	biological_process	proton transmembrane transport
AI	0005515	molecular_function	protein binding
AI	0005739	cellular_component	mitochondrion
AI	0005743	cellular_component	mitochondrial inner membrane
AI	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
AI	0008121	molecular_function	quinol-cytochrome-c reductase activity
AI	0009410	biological_process	response to xenobiotic stimulus
AI	0009725	biological_process	response to hormone
AI	0016020	cellular_component	membrane
AI	0016491	molecular_function	oxidoreductase activity
AI	0022904	biological_process	respiratory electron transport chain
AI	0031966	cellular_component	mitochondrial membrane
AI	0043209	cellular_component	myelin sheath
AI	0044877	molecular_function	protein-containing complex binding
AI	0045275	cellular_component	respiratory chain complex III
AI	0046872	molecular_function	metal ion binding
AI	0051536	molecular_function	iron-sulfur cluster binding
AI	0051537	molecular_function	2 iron, 2 sulfur cluster binding
AI	1902600	biological_process	proton transmembrane transport
AJ	0005739	cellular_component	mitochondrion
AJ	0005743	cellular_component	mitochondrial inner membrane
AJ	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
AJ	0016020	cellular_component	membrane
AJ	0022904	biological_process	respiratory electron transport chain
AJ	0045275	cellular_component	respiratory chain complex III
AJ	0045333	biological_process	cellular respiration
AK	0005739	cellular_component	mitochondrion
AK	0005743	cellular_component	mitochondrial inner membrane
AK	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
AK	0022904	biological_process	respiratory electron transport chain
AK	0045275	cellular_component	respiratory chain complex III
AK	0045333	biological_process	cellular respiration
Aa	0005515	molecular_function	protein binding
Aa	0005739	cellular_component	mitochondrion
Aa	0005743	cellular_component	mitochondrial inner membrane
Aa	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
Aa	0006627	biological_process	protein processing involved in protein targeting to mitochondrion
Aa	0014823	biological_process	response to activity
Aa	0017087	cellular_component	mitochondrial processing peptidase complex
Aa	0022904	biological_process	respiratory electron transport chain
Aa	0031625	molecular_function	ubiquitin protein ligase binding
Aa	0034551	biological_process	mitochondrial respiratory chain complex III assembly
Aa	0043209	cellular_component	myelin sheath
Aa	0043279	biological_process	response to alkaloid
Aa	0044877	molecular_function	protein-containing complex binding
Aa	0045275	cellular_component	respiratory chain complex III
Aa	0045333	biological_process	cellular respiration
Aa	0046872	molecular_function	metal ion binding
Ab	0004222	molecular_function	metalloendopeptidase activity
Ab	0005515	molecular_function	protein binding
Ab	0005654	cellular_component	nucleoplasm
Ab	0005739	cellular_component	mitochondrion
Ab	0005743	cellular_component	mitochondrial inner membrane
Ab	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
Ab	0006508	biological_process	proteolysis
Ab	0009410	biological_process	response to xenobiotic stimulus
Ab	0022904	biological_process	respiratory electron transport chain
Ab	0043209	cellular_component	myelin sheath
Ab	0044877	molecular_function	protein-containing complex binding
Ab	0045275	cellular_component	respiratory chain complex III
Ab	0045333	biological_process	cellular respiration
Ab	0046872	molecular_function	metal ion binding
Ac	0001666	biological_process	response to hypoxia
Ac	0005739	cellular_component	mitochondrion
Ac	0005743	cellular_component	mitochondrial inner membrane
Ac	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
Ac	0007584	biological_process	response to nutrient
Ac	0008121	molecular_function	quinol-cytochrome-c reductase activity
Ac	0009055	molecular_function	electron transfer activity
Ac	0009410	biological_process	response to xenobiotic stimulus
Ac	0009636	biological_process	response to toxic substance
Ac	0009725	biological_process	response to hormone
Ac	0015990	biological_process	electron transport coupled proton transport
Ac	0016020	cellular_component	membrane
Ac	0016491	molecular_function	oxidoreductase activity
Ac	0022904	biological_process	respiratory electron transport chain
Ac	0031100	biological_process	animal organ regeneration
Ac	0032991	cellular_component	protein-containing complex
Ac	0033590	biological_process	response to cobalamin
Ac	0033762	biological_process	response to glucagon
Ac	0044877	molecular_function	protein-containing complex binding
Ac	0045275	cellular_component	respiratory chain complex III
Ac	0045333	biological_process	cellular respiration
Ac	0045471	biological_process	response to ethanol
Ac	0046686	biological_process	response to cadmium ion
Ac	0046688	biological_process	response to copper ion
Ac	0046689	biological_process	response to mercury ion
Ac	0046872	molecular_function	metal ion binding
Ac	0051592	biological_process	response to calcium ion
Ac	0055093	biological_process	response to hyperoxia
Ac	1904421	biological_process	response to D-galactosamine
Ad	0005515	molecular_function	protein binding
Ad	0005739	cellular_component	mitochondrion
Ad	0005743	cellular_component	mitochondrial inner membrane
Ad	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
Ad	0008121	molecular_function	quinol-cytochrome-c reductase activity
Ad	0009055	molecular_function	electron transfer activity
Ad	0016020	cellular_component	membrane
Ad	0020037	molecular_function	heme binding
Ad	0022904	biological_process	respiratory electron transport chain
Ad	0033762	biological_process	response to glucagon
Ad	0045275	cellular_component	respiratory chain complex III
Ad	0045333	biological_process	cellular respiration
Ad	0046872	molecular_function	metal ion binding
Ad	1902600	biological_process	proton transmembrane transport
Ae	0005515	molecular_function	protein binding
Ae	0005739	cellular_component	mitochondrion
Ae	0005743	cellular_component	mitochondrial inner membrane
Ae	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
Ae	0008121	molecular_function	quinol-cytochrome-c reductase activity
Ae	0009410	biological_process	response to xenobiotic stimulus
Ae	0009725	biological_process	response to hormone
Ae	0016020	cellular_component	membrane
Ae	0016491	molecular_function	oxidoreductase activity
Ae	0022904	biological_process	respiratory electron transport chain
Ae	0031966	cellular_component	mitochondrial membrane
Ae	0043209	cellular_component	myelin sheath
Ae	0044877	molecular_function	protein-containing complex binding
Ae	0045275	cellular_component	respiratory chain complex III
Ae	0046872	molecular_function	metal ion binding
Ae	0051536	molecular_function	iron-sulfur cluster binding
Ae	0051537	molecular_function	2 iron, 2 sulfur cluster binding
Ae	1902600	biological_process	proton transmembrane transport
Af	0005743	cellular_component	mitochondrial inner membrane
Af	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
Af	0016020	cellular_component	membrane
Af	0022904	biological_process	respiratory electron transport chain
Af	0044877	molecular_function	protein-containing complex binding
Af	0045275	cellular_component	respiratory chain complex III
Ag	0005515	molecular_function	protein binding
Ag	0005739	cellular_component	mitochondrion
Ag	0005743	cellular_component	mitochondrial inner membrane
Ag	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
Ag	0016020	cellular_component	membrane
Ag	0021539	biological_process	subthalamus development
Ag	0021548	biological_process	pons development
Ag	0021680	biological_process	cerebellar Purkinje cell layer development
Ag	0021766	biological_process	hippocampus development
Ag	0021794	biological_process	thalamus development
Ag	0021854	biological_process	hypothalamus development
Ag	0021860	biological_process	pyramidal neuron development
Ag	0022904	biological_process	respiratory electron transport chain
Ag	0030901	biological_process	midbrain development
Ag	0045275	cellular_component	respiratory chain complex III
Ag	0045333	biological_process	cellular respiration
Ah	0005739	cellular_component	mitochondrion
Ah	0005743	cellular_component	mitochondrial inner membrane
Ah	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
Ah	0008121	molecular_function	quinol-cytochrome-c reductase activity
Ah	0022904	biological_process	respiratory electron transport chain
Ah	0044877	molecular_function	protein-containing complex binding
Ah	0045275	cellular_component	respiratory chain complex III
Ah	0045333	biological_process	cellular respiration
Ah	1902600	biological_process	proton transmembrane transport
Aj	0005739	cellular_component	mitochondrion
Aj	0005743	cellular_component	mitochondrial inner membrane
Aj	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
Aj	0016020	cellular_component	membrane
Aj	0022904	biological_process	respiratory electron transport chain
Aj	0045275	cellular_component	respiratory chain complex III
Aj	0045333	biological_process	cellular respiration
Ak	0005739	cellular_component	mitochondrion
Ak	0005743	cellular_component	mitochondrial inner membrane
Ak	0006122	biological_process	mitochondrial electron transport, ubiquinol to cytochrome c
Ak	0022904	biological_process	respiratory electron transport chain
Ak	0045275	cellular_component	respiratory chain complex III
Ak	0045333	biological_process	cellular respiration

Functional Information from PROSITE/UniProt

site_id	PS00143
Number of Residues	24
Details	INSULINASE Insulinase family, zinc-binding region signature. GsryedsnnlGtSHLLRLAsSlTT

Chain	Residue	Details
AB	GLY68-THR91

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	16
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"23576753","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"PubMed","id":"23806337","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"Q68FY0","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	2
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"UniProtKB","id":"Q68FY0","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P32551","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	504
Details	Transmembrane: {"description":"Helical","evidences":[{"source":"PubMed","id":"34616041","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7O37","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7O3C","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	2
Details	Binding site: {"description":"axial binding residue","evidences":[{"source":"PROSITE-ProRule","id":"PRU00968","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"34616041","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7O37","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7O3C","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	10
Details	Binding site: {"description":"axial binding residue","evidences":[{"source":"PubMed","id":"34616041","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7O37","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7O3C","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P00157","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	16
Details	Topological domain: {"description":"Mitochondrial matrix","evidences":[{"source":"PubMed","id":"34616041","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7O37","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7O3C","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	202
Details	Domain: {"description":"Cytochrome c","evidences":[{"source":"PROSITE-ProRule","id":"PRU00433","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	4
Details	Binding site: {"description":"covalent","evidences":[{"source":"PubMed","id":"34616041","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7O37","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"7O3C","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	52
Details	Transmembrane: {"description":"Helical","evidences":[{"source":"PubMed","id":"34616041","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7O37","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	272
Details	Topological domain: {"description":"Mitochondrial intermembrane","evidences":[{"source":"PubMed","id":"34616041","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7O37","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	170
Details	Domain: {"description":"Rieske","evidences":[{"source":"PROSITE-ProRule","id":"PRU00628","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI16
Number of Residues	10
Details	Binding site: {"evidences":[{"source":"PubMed","id":"34616041","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"7O37","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI17
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"O14949","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---