8IB8

Human TRiC-PhLP2A-actin complex in the closed state

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000242	cellular_component	pericentriolar material
A	0000792	cellular_component	heterochromatin
A	0001669	cellular_component	acrosomal vesicle
A	0002199	cellular_component	zona pellucida receptor complex
A	0003723	molecular_function	RNA binding
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005794	cellular_component	Golgi apparatus
A	0005813	cellular_component	centrosome
A	0005815	cellular_component	microtubule organizing center
A	0005829	cellular_component	cytosol
A	0005832	cellular_component	chaperonin-containing T-complex
A	0005856	cellular_component	cytoskeleton
A	0005874	cellular_component	microtubule
A	0006457	biological_process	protein folding
A	0007021	biological_process	tubulin complex assembly
A	0007339	biological_process	binding of sperm to zona pellucida
A	0016887	molecular_function	ATP hydrolysis activity
A	0031625	molecular_function	ubiquitin protein ligase binding
A	0032212	biological_process	positive regulation of telomere maintenance via telomerase
A	0044183	molecular_function	protein folding chaperone
A	0044297	cellular_component	cell body
A	0050821	biological_process	protein stabilization
A	0051082	molecular_function	unfolded protein binding
A	0051973	biological_process	positive regulation of telomerase activity
A	0061077	biological_process	chaperone-mediated protein folding
A	0070062	cellular_component	extracellular exosome
A	0090666	biological_process	scaRNA localization to Cajal body
A	0140662	molecular_function	ATP-dependent protein folding chaperone
A	1904851	biological_process	positive regulation of establishment of protein localization to telomere
A	1904871	biological_process	positive regulation of protein localization to Cajal body
A	1904874	biological_process	positive regulation of telomerase RNA localization to Cajal body
B	0002199	cellular_component	zona pellucida receptor complex
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005576	cellular_component	extracellular region
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0005832	cellular_component	chaperonin-containing T-complex
B	0005874	cellular_component	microtubule
B	0006457	biological_process	protein folding
B	0007339	biological_process	binding of sperm to zona pellucida
B	0016887	molecular_function	ATP hydrolysis activity
B	0031625	molecular_function	ubiquitin protein ligase binding
B	0032212	biological_process	positive regulation of telomere maintenance via telomerase
B	0035578	cellular_component	azurophil granule lumen
B	0044183	molecular_function	protein folding chaperone
B	0044297	cellular_component	cell body
B	0050821	biological_process	protein stabilization
B	0051082	molecular_function	unfolded protein binding
B	0051086	biological_process	chaperone mediated protein folding independent of cofactor
B	0051131	biological_process	chaperone-mediated protein complex assembly
B	0051973	biological_process	positive regulation of telomerase activity
B	0061077	biological_process	chaperone-mediated protein folding
B	0070062	cellular_component	extracellular exosome
B	0090666	biological_process	scaRNA localization to Cajal body
B	0140662	molecular_function	ATP-dependent protein folding chaperone
B	1904851	biological_process	positive regulation of establishment of protein localization to telomere
B	1904871	biological_process	positive regulation of protein localization to Cajal body
B	1904874	biological_process	positive regulation of telomerase RNA localization to Cajal body
C	0002199	cellular_component	zona pellucida receptor complex
C	0003723	molecular_function	RNA binding
C	0005515	molecular_function	protein binding
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0005832	cellular_component	chaperonin-containing T-complex
C	0005856	cellular_component	cytoskeleton
C	0005874	cellular_component	microtubule
C	0006457	biological_process	protein folding
C	0007339	biological_process	binding of sperm to zona pellucida
C	0016887	molecular_function	ATP hydrolysis activity
C	0032212	biological_process	positive regulation of telomere maintenance via telomerase
C	0044183	molecular_function	protein folding chaperone
C	0044297	cellular_component	cell body
C	0050821	biological_process	protein stabilization
C	0051082	molecular_function	unfolded protein binding
C	0061077	biological_process	chaperone-mediated protein folding
C	0070062	cellular_component	extracellular exosome
C	0140662	molecular_function	ATP-dependent protein folding chaperone
C	1904851	biological_process	positive regulation of establishment of protein localization to telomere
C	1904871	biological_process	positive regulation of protein localization to Cajal body
C	1904874	biological_process	positive regulation of telomerase RNA localization to Cajal body
D	0002199	cellular_component	zona pellucida receptor complex
D	0003723	molecular_function	RNA binding
D	0005515	molecular_function	protein binding
D	0005524	molecular_function	ATP binding
D	0005654	cellular_component	nucleoplasm
D	0005737	cellular_component	cytoplasm
D	0005813	cellular_component	centrosome
D	0005829	cellular_component	cytosol
D	0005832	cellular_component	chaperonin-containing T-complex
D	0005856	cellular_component	cytoskeleton
D	0005874	cellular_component	microtubule
D	0006457	biological_process	protein folding
D	0007339	biological_process	binding of sperm to zona pellucida
D	0016887	molecular_function	ATP hydrolysis activity
D	0032212	biological_process	positive regulation of telomere maintenance via telomerase
D	0042470	cellular_component	melanosome
D	0042995	cellular_component	cell projection
D	0044183	molecular_function	protein folding chaperone
D	0044297	cellular_component	cell body
D	0050821	biological_process	protein stabilization
D	0051082	molecular_function	unfolded protein binding
D	0051973	biological_process	positive regulation of telomerase activity
D	0061077	biological_process	chaperone-mediated protein folding
D	0070062	cellular_component	extracellular exosome
D	0090666	biological_process	scaRNA localization to Cajal body
D	0140662	molecular_function	ATP-dependent protein folding chaperone
D	1904851	biological_process	positive regulation of establishment of protein localization to telomere
D	1904871	biological_process	positive regulation of protein localization to Cajal body
D	1904874	biological_process	positive regulation of telomerase RNA localization to Cajal body
E	0003730	molecular_function	mRNA 3'-UTR binding
E	0005515	molecular_function	protein binding
E	0005524	molecular_function	ATP binding
E	0005737	cellular_component	cytoplasm
E	0005813	cellular_component	centrosome
E	0005829	cellular_component	cytosol
E	0005832	cellular_component	chaperonin-containing T-complex
E	0005856	cellular_component	cytoskeleton
E	0005874	cellular_component	microtubule
E	0006457	biological_process	protein folding
E	0007339	biological_process	binding of sperm to zona pellucida
E	0009615	biological_process	response to virus
E	0016887	molecular_function	ATP hydrolysis activity
E	0031681	molecular_function	G-protein beta-subunit binding
E	0032212	biological_process	positive regulation of telomere maintenance via telomerase
E	0044183	molecular_function	protein folding chaperone
E	0044297	cellular_component	cell body
E	0048027	molecular_function	mRNA 5'-UTR binding
E	0048487	molecular_function	beta-tubulin binding
E	0050821	biological_process	protein stabilization
E	0051082	molecular_function	unfolded protein binding
E	0061077	biological_process	chaperone-mediated protein folding
E	0070062	cellular_component	extracellular exosome
E	0140662	molecular_function	ATP-dependent protein folding chaperone
E	1904851	biological_process	positive regulation of establishment of protein localization to telomere
E	1904871	biological_process	positive regulation of protein localization to Cajal body
E	1904874	biological_process	positive regulation of telomerase RNA localization to Cajal body
F	0003723	molecular_function	RNA binding
F	0005515	molecular_function	protein binding
F	0005524	molecular_function	ATP binding
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0005832	cellular_component	chaperonin-containing T-complex
F	0005874	cellular_component	microtubule
F	0006457	biological_process	protein folding
F	0016887	molecular_function	ATP hydrolysis activity
F	0032212	biological_process	positive regulation of telomere maintenance via telomerase
F	0044183	molecular_function	protein folding chaperone
F	0050821	biological_process	protein stabilization
F	0051082	molecular_function	unfolded protein binding
F	0061077	biological_process	chaperone-mediated protein folding
F	0070062	cellular_component	extracellular exosome
F	0071987	molecular_function	WD40-repeat domain binding
F	0140662	molecular_function	ATP-dependent protein folding chaperone
F	1904851	biological_process	positive regulation of establishment of protein localization to telomere
F	1904871	biological_process	positive regulation of protein localization to Cajal body
F	1904874	biological_process	positive regulation of telomerase RNA localization to Cajal body
G	0005515	molecular_function	protein binding
G	0005524	molecular_function	ATP binding
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0005832	cellular_component	chaperonin-containing T-complex
G	0005874	cellular_component	microtubule
G	0006457	biological_process	protein folding
G	0007339	biological_process	binding of sperm to zona pellucida
G	0016887	molecular_function	ATP hydrolysis activity
G	0032212	biological_process	positive regulation of telomere maintenance via telomerase
G	0044183	molecular_function	protein folding chaperone
G	0044297	cellular_component	cell body
G	0050821	biological_process	protein stabilization
G	0051082	molecular_function	unfolded protein binding
G	0061077	biological_process	chaperone-mediated protein folding
G	0070062	cellular_component	extracellular exosome
G	0140662	molecular_function	ATP-dependent protein folding chaperone
G	1904851	biological_process	positive regulation of establishment of protein localization to telomere
G	1904871	biological_process	positive regulation of protein localization to Cajal body
G	1904874	biological_process	positive regulation of telomerase RNA localization to Cajal body
H	0002199	cellular_component	zona pellucida receptor complex
H	0005515	molecular_function	protein binding
H	0005524	molecular_function	ATP binding
H	0005576	cellular_component	extracellular region
H	0005654	cellular_component	nucleoplasm
H	0005737	cellular_component	cytoplasm
H	0005813	cellular_component	centrosome
H	0005829	cellular_component	cytosol
H	0005832	cellular_component	chaperonin-containing T-complex
H	0005856	cellular_component	cytoskeleton
H	0005874	cellular_component	microtubule
H	0005929	cellular_component	cilium
H	0006457	biological_process	protein folding
H	0007339	biological_process	binding of sperm to zona pellucida
H	0016887	molecular_function	ATP hydrolysis activity
H	0032212	biological_process	positive regulation of telomere maintenance via telomerase
H	0034774	cellular_component	secretory granule lumen
H	0035578	cellular_component	azurophil granule lumen
H	0044183	molecular_function	protein folding chaperone
H	0044297	cellular_component	cell body
H	0045111	cellular_component	intermediate filament cytoskeleton
H	0045296	molecular_function	cadherin binding
H	0050821	biological_process	protein stabilization
H	0051082	molecular_function	unfolded protein binding
H	0061077	biological_process	chaperone-mediated protein folding
H	0070062	cellular_component	extracellular exosome
H	0140662	molecular_function	ATP-dependent protein folding chaperone
H	1904813	cellular_component	ficolin-1-rich granule lumen
H	1904851	biological_process	positive regulation of establishment of protein localization to telomere
H	1904871	biological_process	positive regulation of protein localization to Cajal body
H	1904874	biological_process	positive regulation of telomerase RNA localization to Cajal body
I	0000242	cellular_component	pericentriolar material
I	0000792	cellular_component	heterochromatin
I	0001669	cellular_component	acrosomal vesicle
I	0002199	cellular_component	zona pellucida receptor complex
I	0003723	molecular_function	RNA binding
I	0005515	molecular_function	protein binding
I	0005524	molecular_function	ATP binding
I	0005737	cellular_component	cytoplasm
I	0005794	cellular_component	Golgi apparatus
I	0005813	cellular_component	centrosome
I	0005815	cellular_component	microtubule organizing center
I	0005829	cellular_component	cytosol
I	0005832	cellular_component	chaperonin-containing T-complex
I	0005856	cellular_component	cytoskeleton
I	0005874	cellular_component	microtubule
I	0006457	biological_process	protein folding
I	0007021	biological_process	tubulin complex assembly
I	0007339	biological_process	binding of sperm to zona pellucida
I	0016887	molecular_function	ATP hydrolysis activity
I	0031625	molecular_function	ubiquitin protein ligase binding
I	0032212	biological_process	positive regulation of telomere maintenance via telomerase
I	0044183	molecular_function	protein folding chaperone
I	0044297	cellular_component	cell body
I	0050821	biological_process	protein stabilization
I	0051082	molecular_function	unfolded protein binding
I	0051973	biological_process	positive regulation of telomerase activity
I	0061077	biological_process	chaperone-mediated protein folding
I	0070062	cellular_component	extracellular exosome
I	0090666	biological_process	scaRNA localization to Cajal body
I	0140662	molecular_function	ATP-dependent protein folding chaperone
I	1904851	biological_process	positive regulation of establishment of protein localization to telomere
I	1904871	biological_process	positive regulation of protein localization to Cajal body
I	1904874	biological_process	positive regulation of telomerase RNA localization to Cajal body
J	0002199	cellular_component	zona pellucida receptor complex
J	0005515	molecular_function	protein binding
J	0005524	molecular_function	ATP binding
J	0005576	cellular_component	extracellular region
J	0005737	cellular_component	cytoplasm
J	0005829	cellular_component	cytosol
J	0005832	cellular_component	chaperonin-containing T-complex
J	0005874	cellular_component	microtubule
J	0006457	biological_process	protein folding
J	0007339	biological_process	binding of sperm to zona pellucida
J	0016887	molecular_function	ATP hydrolysis activity
J	0031625	molecular_function	ubiquitin protein ligase binding
J	0032212	biological_process	positive regulation of telomere maintenance via telomerase
J	0035578	cellular_component	azurophil granule lumen
J	0044183	molecular_function	protein folding chaperone
J	0044297	cellular_component	cell body
J	0050821	biological_process	protein stabilization
J	0051082	molecular_function	unfolded protein binding
J	0051086	biological_process	chaperone mediated protein folding independent of cofactor
J	0051131	biological_process	chaperone-mediated protein complex assembly
J	0051973	biological_process	positive regulation of telomerase activity
J	0061077	biological_process	chaperone-mediated protein folding
J	0070062	cellular_component	extracellular exosome
J	0090666	biological_process	scaRNA localization to Cajal body
J	0140662	molecular_function	ATP-dependent protein folding chaperone
J	1904851	biological_process	positive regulation of establishment of protein localization to telomere
J	1904871	biological_process	positive regulation of protein localization to Cajal body
J	1904874	biological_process	positive regulation of telomerase RNA localization to Cajal body
K	0002199	cellular_component	zona pellucida receptor complex
K	0003723	molecular_function	RNA binding
K	0005515	molecular_function	protein binding
K	0005524	molecular_function	ATP binding
K	0005737	cellular_component	cytoplasm
K	0005829	cellular_component	cytosol
K	0005832	cellular_component	chaperonin-containing T-complex
K	0005856	cellular_component	cytoskeleton
K	0005874	cellular_component	microtubule
K	0006457	biological_process	protein folding
K	0007339	biological_process	binding of sperm to zona pellucida
K	0016887	molecular_function	ATP hydrolysis activity
K	0032212	biological_process	positive regulation of telomere maintenance via telomerase
K	0044183	molecular_function	protein folding chaperone
K	0044297	cellular_component	cell body
K	0050821	biological_process	protein stabilization
K	0051082	molecular_function	unfolded protein binding
K	0061077	biological_process	chaperone-mediated protein folding
K	0070062	cellular_component	extracellular exosome
K	0140662	molecular_function	ATP-dependent protein folding chaperone
K	1904851	biological_process	positive regulation of establishment of protein localization to telomere
K	1904871	biological_process	positive regulation of protein localization to Cajal body
K	1904874	biological_process	positive regulation of telomerase RNA localization to Cajal body
L	0002199	cellular_component	zona pellucida receptor complex
L	0003723	molecular_function	RNA binding
L	0005515	molecular_function	protein binding
L	0005524	molecular_function	ATP binding
L	0005654	cellular_component	nucleoplasm
L	0005737	cellular_component	cytoplasm
L	0005813	cellular_component	centrosome
L	0005829	cellular_component	cytosol
L	0005832	cellular_component	chaperonin-containing T-complex
L	0005856	cellular_component	cytoskeleton
L	0005874	cellular_component	microtubule
L	0006457	biological_process	protein folding
L	0007339	biological_process	binding of sperm to zona pellucida
L	0016887	molecular_function	ATP hydrolysis activity
L	0032212	biological_process	positive regulation of telomere maintenance via telomerase
L	0042470	cellular_component	melanosome
L	0042995	cellular_component	cell projection
L	0044183	molecular_function	protein folding chaperone
L	0044297	cellular_component	cell body
L	0050821	biological_process	protein stabilization
L	0051082	molecular_function	unfolded protein binding
L	0051973	biological_process	positive regulation of telomerase activity
L	0061077	biological_process	chaperone-mediated protein folding
L	0070062	cellular_component	extracellular exosome
L	0090666	biological_process	scaRNA localization to Cajal body
L	0140662	molecular_function	ATP-dependent protein folding chaperone
L	1904851	biological_process	positive regulation of establishment of protein localization to telomere
L	1904871	biological_process	positive regulation of protein localization to Cajal body
L	1904874	biological_process	positive regulation of telomerase RNA localization to Cajal body
M	0003730	molecular_function	mRNA 3'-UTR binding
M	0005515	molecular_function	protein binding
M	0005524	molecular_function	ATP binding
M	0005737	cellular_component	cytoplasm
M	0005813	cellular_component	centrosome
M	0005829	cellular_component	cytosol
M	0005832	cellular_component	chaperonin-containing T-complex
M	0005856	cellular_component	cytoskeleton
M	0005874	cellular_component	microtubule
M	0006457	biological_process	protein folding
M	0007339	biological_process	binding of sperm to zona pellucida
M	0009615	biological_process	response to virus
M	0016887	molecular_function	ATP hydrolysis activity
M	0031681	molecular_function	G-protein beta-subunit binding
M	0032212	biological_process	positive regulation of telomere maintenance via telomerase
M	0044183	molecular_function	protein folding chaperone
M	0044297	cellular_component	cell body
M	0048027	molecular_function	mRNA 5'-UTR binding
M	0048487	molecular_function	beta-tubulin binding
M	0050821	biological_process	protein stabilization
M	0051082	molecular_function	unfolded protein binding
M	0061077	biological_process	chaperone-mediated protein folding
M	0070062	cellular_component	extracellular exosome
M	0140662	molecular_function	ATP-dependent protein folding chaperone
M	1904851	biological_process	positive regulation of establishment of protein localization to telomere
M	1904871	biological_process	positive regulation of protein localization to Cajal body
M	1904874	biological_process	positive regulation of telomerase RNA localization to Cajal body
N	0003723	molecular_function	RNA binding
N	0005515	molecular_function	protein binding
N	0005524	molecular_function	ATP binding
N	0005737	cellular_component	cytoplasm
N	0005829	cellular_component	cytosol
N	0005832	cellular_component	chaperonin-containing T-complex
N	0005874	cellular_component	microtubule
N	0006457	biological_process	protein folding
N	0016887	molecular_function	ATP hydrolysis activity
N	0032212	biological_process	positive regulation of telomere maintenance via telomerase
N	0044183	molecular_function	protein folding chaperone
N	0050821	biological_process	protein stabilization
N	0051082	molecular_function	unfolded protein binding
N	0061077	biological_process	chaperone-mediated protein folding
N	0070062	cellular_component	extracellular exosome
N	0071987	molecular_function	WD40-repeat domain binding
N	0140662	molecular_function	ATP-dependent protein folding chaperone
N	1904851	biological_process	positive regulation of establishment of protein localization to telomere
N	1904871	biological_process	positive regulation of protein localization to Cajal body
N	1904874	biological_process	positive regulation of telomerase RNA localization to Cajal body
O	0005515	molecular_function	protein binding
O	0005524	molecular_function	ATP binding
O	0005737	cellular_component	cytoplasm
O	0005829	cellular_component	cytosol
O	0005832	cellular_component	chaperonin-containing T-complex
O	0005874	cellular_component	microtubule
O	0006457	biological_process	protein folding
O	0007339	biological_process	binding of sperm to zona pellucida
O	0016887	molecular_function	ATP hydrolysis activity
O	0032212	biological_process	positive regulation of telomere maintenance via telomerase
O	0044183	molecular_function	protein folding chaperone
O	0044297	cellular_component	cell body
O	0050821	biological_process	protein stabilization
O	0051082	molecular_function	unfolded protein binding
O	0061077	biological_process	chaperone-mediated protein folding
O	0070062	cellular_component	extracellular exosome
O	0140662	molecular_function	ATP-dependent protein folding chaperone
O	1904851	biological_process	positive regulation of establishment of protein localization to telomere
O	1904871	biological_process	positive regulation of protein localization to Cajal body
O	1904874	biological_process	positive regulation of telomerase RNA localization to Cajal body
P	0002199	cellular_component	zona pellucida receptor complex
P	0005515	molecular_function	protein binding
P	0005524	molecular_function	ATP binding
P	0005576	cellular_component	extracellular region
P	0005654	cellular_component	nucleoplasm
P	0005737	cellular_component	cytoplasm
P	0005813	cellular_component	centrosome
P	0005829	cellular_component	cytosol
P	0005832	cellular_component	chaperonin-containing T-complex
P	0005856	cellular_component	cytoskeleton
P	0005874	cellular_component	microtubule
P	0005929	cellular_component	cilium
P	0006457	biological_process	protein folding
P	0007339	biological_process	binding of sperm to zona pellucida
P	0016887	molecular_function	ATP hydrolysis activity
P	0032212	biological_process	positive regulation of telomere maintenance via telomerase
P	0034774	cellular_component	secretory granule lumen
P	0035578	cellular_component	azurophil granule lumen
P	0044183	molecular_function	protein folding chaperone
P	0044297	cellular_component	cell body
P	0045111	cellular_component	intermediate filament cytoskeleton
P	0045296	molecular_function	cadherin binding
P	0050821	biological_process	protein stabilization
P	0051082	molecular_function	unfolded protein binding
P	0061077	biological_process	chaperone-mediated protein folding
P	0070062	cellular_component	extracellular exosome
P	0140662	molecular_function	ATP-dependent protein folding chaperone
P	1904813	cellular_component	ficolin-1-rich granule lumen
P	1904851	biological_process	positive regulation of establishment of protein localization to telomere
P	1904871	biological_process	positive regulation of protein localization to Cajal body
P	1904874	biological_process	positive regulation of telomerase RNA localization to Cajal body
Q	0001525	biological_process	angiogenesis
Q	0001938	biological_process	positive regulation of endothelial cell proliferation
Q	0005515	molecular_function	protein binding
Q	0005654	cellular_component	nucleoplasm
Q	0005737	cellular_component	cytoplasm
Q	0005783	cellular_component	endoplasmic reticulum
Q	0005829	cellular_component	cytosol
Q	0006457	biological_process	protein folding
Q	0006915	biological_process	apoptotic process
Q	0010628	biological_process	positive regulation of gene expression
Q	0030036	biological_process	actin cytoskeleton organization
Q	0032991	cellular_component	protein-containing complex
Q	0043184	molecular_function	vascular endothelial growth factor receptor 2 binding
Q	0044183	molecular_function	protein folding chaperone
Q	0045766	biological_process	positive regulation of angiogenesis
Q	0048471	cellular_component	perinuclear region of cytoplasm
Q	0050730	biological_process	regulation of peptidyl-tyrosine phosphorylation
Q	0050821	biological_process	protein stabilization
Q	0061077	biological_process	chaperone-mediated protein folding
Q	0097356	cellular_component	perinucleolar compartment
Q	1903645	biological_process	negative regulation of chaperone-mediated protein folding
Q	2000059	biological_process	negative regulation of ubiquitin-dependent protein catabolic process
S	0000079	biological_process	regulation of cyclin-dependent protein serine/threonine kinase activity
S	0000776	cellular_component	kinetochore
S	0000785	cellular_component	chromatin
S	0000786	cellular_component	nucleosome
S	0001738	biological_process	morphogenesis of a polarized epithelium
S	0005200	molecular_function	structural constituent of cytoskeleton
S	0005515	molecular_function	protein binding
S	0005524	molecular_function	ATP binding
S	0005615	cellular_component	extracellular space
S	0005634	cellular_component	nucleus
S	0005654	cellular_component	nucleoplasm
S	0005737	cellular_component	cytoplasm
S	0005829	cellular_component	cytosol
S	0005856	cellular_component	cytoskeleton
S	0005884	cellular_component	actin filament
S	0005886	cellular_component	plasma membrane
S	0005903	cellular_component	brush border
S	0005911	cellular_component	cell-cell junction
S	0005912	cellular_component	adherens junction
S	0005925	cellular_component	focal adhesion
S	0006338	biological_process	chromatin remodeling
S	0006357	biological_process	regulation of transcription by RNA polymerase II
S	0007163	biological_process	establishment or maintenance of cell polarity
S	0007409	biological_process	axonogenesis
S	0008284	biological_process	positive regulation of cell population proliferation
S	0015629	cellular_component	actin cytoskeleton
S	0016020	cellular_component	membrane
S	0016363	cellular_component	nuclear matrix
S	0016514	cellular_component	SWI/SNF complex
S	0016586	cellular_component	RSC-type complex
S	0016787	molecular_function	hydrolase activity
S	0016887	molecular_function	ATP hydrolysis activity
S	0019894	molecular_function	kinesin binding
S	0019901	molecular_function	protein kinase binding
S	0021762	biological_process	substantia nigra development
S	0022898	biological_process	regulation of transmembrane transporter activity
S	0030027	cellular_component	lamellipodium
S	0030071	biological_process	regulation of mitotic metaphase/anaphase transition
S	0030424	cellular_component	axon
S	0030863	cellular_component	cortical cytoskeleton
S	0030957	molecular_function	Tat protein binding
S	0031492	molecular_function	nucleosomal DNA binding
S	0031982	cellular_component	vesicle
S	0032091	biological_process	negative regulation of protein binding
S	0032991	cellular_component	protein-containing complex
S	0034333	biological_process	adherens junction assembly
S	0035060	cellular_component	brahma complex
S	0035267	cellular_component	NuA4 histone acetyltransferase complex
S	0035633	biological_process	maintenance of blood-brain barrier
S	0036464	cellular_component	cytoplasmic ribonucleoprotein granule
S	0042802	molecular_function	identical protein binding
S	0042981	biological_process	regulation of apoptotic process
S	0043296	cellular_component	apical junction complex
S	0044305	cellular_component	calyx of Held
S	0045176	biological_process	apical protein localization
S	0045202	cellular_component	synapse
S	0045582	biological_process	positive regulation of T cell differentiation
S	0045596	biological_process	negative regulation of cell differentiation
S	0045597	biological_process	positive regulation of cell differentiation
S	0045663	biological_process	positive regulation of myoblast differentiation
S	0045893	biological_process	positive regulation of DNA-templated transcription
S	0048156	molecular_function	tau protein binding
S	0048870	biological_process	cell motility
S	0050998	molecular_function	nitric-oxide synthase binding
S	0051621	biological_process	regulation of norepinephrine uptake
S	0051623	biological_process	positive regulation of norepinephrine uptake
S	0051726	biological_process	regulation of cell cycle
S	0070062	cellular_component	extracellular exosome
S	0070160	cellular_component	tight junction
S	0070316	biological_process	regulation of G0 to G1 transition
S	0070527	biological_process	platelet aggregation
S	0071564	cellular_component	npBAF complex
S	0071565	cellular_component	nBAF complex
S	0071896	biological_process	protein localization to adherens junction
S	0072562	cellular_component	blood microparticle
S	0072749	biological_process	cellular response to cytochalasin B
S	0097433	cellular_component	dense body
S	0098685	cellular_component	Schaffer collateral - CA1 synapse
S	0098793	cellular_component	presynapse
S	0098871	cellular_component	postsynaptic actin cytoskeleton
S	0098973	molecular_function	structural constituent of postsynaptic actin cytoskeleton
S	0098974	biological_process	postsynaptic actin cytoskeleton organization
S	0098978	cellular_component	glutamatergic synapse
S	0140092	cellular_component	bBAF complex
S	0140288	cellular_component	GBAF complex
S	0150111	biological_process	regulation of transepithelial transport
S	1900242	biological_process	regulation of synaptic vesicle endocytosis
S	1902459	biological_process	positive regulation of stem cell population maintenance
S	1903076	biological_process	regulation of protein localization to plasma membrane
S	1905168	biological_process	positive regulation of double-strand break repair via homologous recombination
S	1990904	cellular_component	ribonucleoprotein complex
S	2000045	biological_process	regulation of G1/S transition of mitotic cell cycle
S	2000779	biological_process	regulation of double-strand break repair
S	2000781	biological_process	positive regulation of double-strand break repair
S	2000819	biological_process	regulation of nucleotide-excision repair

Functional Information from PROSITE/UniProt

site_id	PS00107
Number of Residues	26
Details	PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. VGDGTTSVTVlAaellreaesl........IAKK

Chain	Residue	Details
B	VAL95-LYS120

---

site_id	PS00141
Number of Residues	12
Details	ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. AIADTGANVVVT

Chain	Residue	Details
H	ALA282-THR293

---

site_id	PS00406
Number of Residues	11
Details	ACTINS_1 Actins signature 1. YVGDEAQs.KRG

Chain	Residue	Details
S	TYR53-GLY63

---

site_id	PS00432
Number of Residues	9
Details	ACTINS_2 Actins signature 2. WISKqEYDE

Chain	Residue	Details
S	TRP356-GLU364

---

site_id	PS00750
Number of Residues	13
Details	TCP1_1 Chaperonins TCP-1 signature 1. RTtLGPrGmdKLI

Chain	Residue	Details
G	ARG37-ILE49
E	ARG49-MET61
F	ARG35-LEU47
A	LYS33-LEU45
D	ARG49-ILE61
H	ARG44-VAL56
B	LYS40-LEU52
C	ARG38-LEU50

---

site_id	PS00751
Number of Residues	17
Details	TCP1_2 Chaperonins TCP-1 signature 2. ISNDGATILklLdVvHP

Chain	Residue	Details
G	ILE58-PRO74
E	VAL70-GLN86
F	LEU56-PRO72
A	ILE54-PRO70
D	ILE70-PRO86
H	VAL65-PRO81
B	VAL63-PRO79
C	MET59-PRO75

---

site_id	PS00995
Number of Residues	9
Details	TCP1_3 Chaperonins TCP-1 signature 3. QDaeVGDGT

Chain	Residue	Details
G	GLN86-THR94
E	GLN98-THR106
F	GLN84-THR92
A	GLN82-THR90
D	GLN98-THR106
H	GLN93-THR101
B	GLN91-THR99
C	GLN87-THR95

---

site_id	PS01132
Number of Residues	13
Details	ACTINS_ACT_LIKE Actins and actin-related proteins signature. LLTEApLNPkaNR

Chain	Residue	Details
S	LEU104-ARG116

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	MOD_RES: N-acetylmethionine => ECO:0000269|PubMed:36173861, ECO:0007744|PubMed:22814378

Chain	Residue	Details
S	MET1
P	ALA2

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: N-acetylaspartate; in Actin, cytoplasmic 1, N-terminally processed => ECO:0000269|PubMed:29581253, ECO:0000269|PubMed:30028079, ECO:0000269|Ref.8, ECO:0007744|PubMed:19413330, ECO:0007744|PubMed:22223895, ECO:0007744|PubMed:22814378, ECO:0007744|PubMed:25944712

Chain	Residue	Details
S	ASP2
P	SER23
O	LYS67
O	LYS320

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	MOD_RES: Methionine (R)-sulfoxide => ECO:0000269|PubMed:29343822

Chain	Residue	Details
S	MET44
S	MET47
F	LYS377
F	LYS388
N	LYS199
N	LYS365
N	LYS377
N	LYS388

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: Tele-methylhistidine => ECO:0000269|PubMed:30526847, ECO:0000269|PubMed:30626964, ECO:0000269|PubMed:30785395, ECO:0000269|PubMed:31388018, ECO:0000269|PubMed:32503840

Chain	Residue	Details
S	HIS73
P	SER537
M	LYS210
M	LYS214
M	LYS265
M	LYS275
M	LYS279
M	LYS392
H	SER213
H	SER269
H	SER317
H	SER537
P	SER162
P	SER213
P	SER269
P	SER317

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	MOD_RES: N6-methyllysine => ECO:0000269|PubMed:23673617

Chain	Residue	Details
S	LYS84
H	LYS400
H	LYS466
P	LYS318
P	LYS400
P	LYS466

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	CROSSLNK: (Microbial infection) Isoglutamyl lysine isopeptide (Lys-Glu) (interchain with E-270); by Vibrio toxins RtxA and VgrG1 => ECO:0000305|PubMed:19015515

Chain	Residue	Details
S	LYS50
P	TYR505

---

site_id	SWS_FT_FI7
Number of Residues	2
Details	CROSSLNK: (Microbial infection) Isoglutamyl lysine isopeptide (Glu-Lys) (interchain with K-50); by Vibrio toxins RtxA and VgrG1 => ECO:0000305|PubMed:19015515

Chain	Residue	Details
H	LYS224
S	GLU270
H	LYS260
P	LYS224
P	LYS254
P	LYS260

---

site_id	SWS_FT_FI8
Number of Residues	4
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:25755297, ECO:0007744|PubMed:28112733

Chain	Residue	Details
C	THR430
H	LYS539
K	THR430
P	LYS539

---

site_id	SWS_FT_FI9
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1) => ECO:0007744|PubMed:25114211

Chain	Residue	Details
H	LYS459
P	LYS459
C	LYS249
K	LYS15
K	LYS248
K	LYS249

---

site_id	SWS_FT_FI10
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:25218447, ECO:0007744|PubMed:25755297, ECO:0007744|PubMed:28112733

Chain	Residue	Details
H	LYS534
P	LYS534
K	LYS381

---