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8I9Y

Cryo-EM structure of a Chaetomium thermophilum pre-60S ribosomal subunit - Ytm1-2

This is a non-PDB format compatible entry.
Functional Information from GO Data
ChainGOidnamespacecontents
CA0000027biological_processribosomal large subunit assembly
CA0003723molecular_functionRNA binding
CA0005634cellular_componentnucleus
CA0005730cellular_componentnucleolus
CA0006364biological_processrRNA processing
CA0019843molecular_functionrRNA binding
CA0042254biological_processribosome biogenesis
CC0000463biological_processmaturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CC0000466biological_processmaturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CC0005634cellular_componentnucleus
CC0005654cellular_componentnucleoplasm
CC0005730cellular_componentnucleolus
CC0006364biological_processrRNA processing
CC0030687cellular_componentpreribosome, large subunit precursor
CC0042254biological_processribosome biogenesis
CC0042273biological_processribosomal large subunit biogenesis
CC0043021molecular_functionribonucleoprotein complex binding
CC0070545cellular_componentPeBoW complex
CD0000463biological_processmaturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CD0000466biological_processmaturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CD0005634cellular_componentnucleus
CD0005654cellular_componentnucleoplasm
CD0005730cellular_componentnucleolus
CD0006364biological_processrRNA processing
CD0030687cellular_componentpreribosome, large subunit precursor
CD0042254biological_processribosome biogenesis
CD0042273biological_processribosomal large subunit biogenesis
CD0043021molecular_functionribonucleoprotein complex binding
CD0070545cellular_componentPeBoW complex
CE0003676molecular_functionnucleic acid binding
CE0003689molecular_functionDNA clamp loader activity
CE0003723molecular_functionRNA binding
CE0003724molecular_functionRNA helicase activity
CE0004386molecular_functionhelicase activity
CE0005524molecular_functionATP binding
CE0005730cellular_componentnucleolus
CE0006338biological_processchromatin remodeling
CE0006364biological_processrRNA processing
CE0016787molecular_functionhydrolase activity
CE0016887molecular_functionATP hydrolysis activity
CE0042254biological_processribosome biogenesis
CE0061775molecular_functioncohesin loader activity
CE0140584molecular_functionchromatin extrusion motor activity
CE0140588biological_processchromatin looping
CE0140665molecular_functionATP-dependent H3-H4 histone complex chaperone activity
CE0140849molecular_functionATP-dependent H2AZ histone chaperone activity
CF0000027biological_processribosomal large subunit assembly
CF0000956biological_processnuclear-transcribed mRNA catabolic process
CF0003723molecular_functionRNA binding
CF0005634cellular_componentnucleus
CF0005730cellular_componentnucleolus
CF0005737cellular_componentcytoplasm
CF0005840cellular_componentribosome
CF0006364biological_processrRNA processing
CF0030687cellular_componentpreribosome, large subunit precursor
CF0042273biological_processribosomal large subunit biogenesis
CF1990904cellular_componentribonucleoprotein complex
CG0003723molecular_functionRNA binding
CG0005634cellular_componentnucleus
CG0005730cellular_componentnucleolus
CG0042254biological_processribosome biogenesis
CG0042255biological_processribosome assembly
CH0005525molecular_functionGTP binding
CH0005634cellular_componentnucleus
CH0005730cellular_componentnucleolus
CH0042254biological_processribosome biogenesis
CH0046872molecular_functionmetal ion binding
CI0003676molecular_functionnucleic acid binding
CI0003723molecular_functionRNA binding
CI0005730cellular_componentnucleolus
CJ0000463biological_processmaturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CJ0000466biological_processmaturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CJ0003723molecular_functionRNA binding
CJ0005634cellular_componentnucleus
CJ0005654cellular_componentnucleoplasm
CJ0005730cellular_componentnucleolus
CJ0006364biological_processrRNA processing
CJ0030687cellular_componentpreribosome, large subunit precursor
CJ0042254biological_processribosome biogenesis
CJ0042273biological_processribosomal large subunit biogenesis
CJ0043021molecular_functionribonucleoprotein complex binding
CJ0070545cellular_componentPeBoW complex
CK0005634cellular_componentnucleus
CK0005730cellular_componentnucleolus
CK0006364biological_processrRNA processing
CK0042254biological_processribosome biogenesis
CK1990904cellular_componentribonucleoprotein complex
CL0005525molecular_functionGTP binding
CL0005634cellular_componentnucleus
CL0005730cellular_componentnucleolus
CM0000463biological_processmaturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CM0003723molecular_functionRNA binding
CM0003735molecular_functionstructural constituent of ribosome
CM0005840cellular_componentribosome
CM0022625cellular_componentcytosolic large ribosomal subunit
CM1990904cellular_componentribonucleoprotein complex
CN0000054biological_processribosomal subunit export from nucleus
CN0003743molecular_functiontranslation initiation factor activity
CN0005634cellular_componentnucleus
CN0005730cellular_componentnucleolus
CN0005737cellular_componentcytoplasm
CN0006412biological_processtranslation
CN0006413biological_processtranslational initiation
CN0042254biological_processribosome biogenesis
CN0042256biological_processcytosolic ribosome assembly
CN0042273biological_processribosomal large subunit biogenesis
CN0043022molecular_functionribosome binding
CN0043023molecular_functionribosomal large subunit binding
CO0030687cellular_componentpreribosome, large subunit precursor
CP0000470biological_processmaturation of LSU-rRNA
CP0001510biological_processRNA methylation
CP0003723molecular_functionRNA binding
CP0005730cellular_componentnucleolus
CP0006396biological_processRNA processing
CP0008168molecular_functionmethyltransferase activity
CP0008173molecular_functionRNA methyltransferase activity
CP0008757molecular_functionS-adenosylmethionine-dependent methyltransferase activity
CP0009383molecular_functionrRNA (cytosine-C5-)-methyltransferase activity
CP0032259biological_processmethylation
CP0042254biological_processribosome biogenesis
CP0070475biological_processrRNA base methylation
CQ0005730cellular_componentnucleolus
CQ0042273biological_processribosomal large subunit biogenesis
CR0005730cellular_componentnucleolus
CR0042273biological_processribosomal large subunit biogenesis
CR1990904cellular_componentribonucleoprotein complex
CS0000463biological_processmaturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CS0000466biological_processmaturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
CS0001510biological_processRNA methylation
CS0005634cellular_componentnucleus
CS0005730cellular_componentnucleolus
CS0006364biological_processrRNA processing
CS0008168molecular_functionmethyltransferase activity
CS0008649molecular_functionrRNA methyltransferase activity
CS0008650molecular_functionrRNA (uridine-2'-O-)-methyltransferase activity
CS0016435molecular_functionrRNA (guanine) methyltransferase activity
CS0030687cellular_componentpreribosome, large subunit precursor
CS0031167biological_processrRNA methylation
CS0032259biological_processmethylation
CS0042254biological_processribosome biogenesis
CT0003682molecular_functionchromatin binding
CT0005634cellular_componentnucleus
CT0005730cellular_componentnucleolus
CT0006270biological_processDNA replication initiation
CT0042254biological_processribosome biogenesis
CU0005634cellular_componentnucleus
CU0005730cellular_componentnucleolus
CU0006364biological_processrRNA processing
CU0030687cellular_componentpreribosome, large subunit precursor
CU0034399cellular_componentnuclear periphery
CU0042254biological_processribosome biogenesis
CU0042273biological_processribosomal large subunit biogenesis
CV0003735molecular_functionstructural constituent of ribosome
CV0005840cellular_componentribosome
CV0006412biological_processtranslation
CV1990904cellular_componentribonucleoprotein complex
CX0003729molecular_functionmRNA binding
CX0005730cellular_componentnucleolus
CX0008298biological_processintracellular mRNA localization
CX0030687cellular_componentpreribosome, large subunit precursor
CX0042254biological_processribosome biogenesis
CX0042273biological_processribosomal large subunit biogenesis
CX0051028biological_processmRNA transport
CY0005634cellular_componentnucleus
CY0005654cellular_componentnucleoplasm
CY0005730cellular_componentnucleolus
CY0030690cellular_componentNoc1p-Noc2p complex
CY0030691cellular_componentNoc2p-Noc3p complex
CY0042273biological_processribosomal large subunit biogenesis
Cz0005634cellular_componentnucleus
Cz0005730cellular_componentnucleolus
Cz0006364biological_processrRNA processing
Cz0042254biological_processribosome biogenesis
LB0003723molecular_functionRNA binding
LB0003735molecular_functionstructural constituent of ribosome
LB0005840cellular_componentribosome
LB0006412biological_processtranslation
LB0022625cellular_componentcytosolic large ribosomal subunit
LB1990904cellular_componentribonucleoprotein complex
LC0003735molecular_functionstructural constituent of ribosome
LC0005840cellular_componentribosome
LC0006412biological_processtranslation
LC1990904cellular_componentribonucleoprotein complex
LE0000027biological_processribosomal large subunit assembly
LE0002181biological_processcytoplasmic translation
LE0003723molecular_functionRNA binding
LE0003735molecular_functionstructural constituent of ribosome
LE0005840cellular_componentribosome
LE0006412biological_processtranslation
LE0022625cellular_componentcytosolic large ribosomal subunit
LE1990904cellular_componentribonucleoprotein complex
LF0000463biological_processmaturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LF0003723molecular_functionRNA binding
LF0003735molecular_functionstructural constituent of ribosome
LF0005840cellular_componentribosome
LF0022625cellular_componentcytosolic large ribosomal subunit
LF1990904cellular_componentribonucleoprotein complex
LG0003723molecular_functionRNA binding
LG0005840cellular_componentribosome
LG0022625cellular_componentcytosolic large ribosomal subunit
LG0042254biological_processribosome biogenesis
LG1990904cellular_componentribonucleoprotein complex
LH0003735molecular_functionstructural constituent of ribosome
LH0005840cellular_componentribosome
LH0006412biological_processtranslation
LH0019843molecular_functionrRNA binding
LK0003735molecular_functionstructural constituent of ribosome
LK0005840cellular_componentribosome
LK0006412biological_processtranslation
LK0022625cellular_componentcytosolic large ribosomal subunit
LK0070180molecular_functionlarge ribosomal subunit rRNA binding
LK1990904cellular_componentribonucleoprotein complex
LL0003723molecular_functionRNA binding
LL0003735molecular_functionstructural constituent of ribosome
LL0005840cellular_componentribosome
LL0006412biological_processtranslation
LL0022625cellular_componentcytosolic large ribosomal subunit
LL1990904cellular_componentribonucleoprotein complex
LM0003723molecular_functionRNA binding
LM0003735molecular_functionstructural constituent of ribosome
LM0005840cellular_componentribosome
LM0006412biological_processtranslation
LM0022625cellular_componentcytosolic large ribosomal subunit
LM0042273biological_processribosomal large subunit biogenesis
LM1990904cellular_componentribonucleoprotein complex
LN0002181biological_processcytoplasmic translation
LN0003723molecular_functionRNA binding
LN0003735molecular_functionstructural constituent of ribosome
LN0005840cellular_componentribosome
LN0006412biological_processtranslation
LN0022625cellular_componentcytosolic large ribosomal subunit
LN1990904cellular_componentribonucleoprotein complex
LO0003729molecular_functionmRNA binding
LO0003735molecular_functionstructural constituent of ribosome
LO0005840cellular_componentribosome
LO0006412biological_processtranslation
LO0015934cellular_componentlarge ribosomal subunit
LO0017148biological_processnegative regulation of translation
LO0022625cellular_componentcytosolic large ribosomal subunit
LO1990904cellular_componentribonucleoprotein complex
LP0002181biological_processcytoplasmic translation
LP0003735molecular_functionstructural constituent of ribosome
LP0005840cellular_componentribosome
LP0006412biological_processtranslation
LP0015934cellular_componentlarge ribosomal subunit
LP0022625cellular_componentcytosolic large ribosomal subunit
LP1990904cellular_componentribonucleoprotein complex
LQ0003723molecular_functionRNA binding
LQ0003735molecular_functionstructural constituent of ribosome
LQ0005840cellular_componentribosome
LQ0006412biological_processtranslation
LQ0022625cellular_componentcytosolic large ribosomal subunit
LQ1990904cellular_componentribonucleoprotein complex
LR0003735molecular_functionstructural constituent of ribosome
LR0005829cellular_componentcytosol
LR0005840cellular_componentribosome
LR0006412biological_processtranslation
LR0006417biological_processregulation of translation
LR0019887molecular_functionprotein kinase regulator activity
LR0022625cellular_componentcytosolic large ribosomal subunit
LR0034198biological_processcellular response to amino acid starvation
LR1990904cellular_componentribonucleoprotein complex
LS0003735molecular_functionstructural constituent of ribosome
LS0005840cellular_componentribosome
LS0006412biological_processtranslation
LS1990904cellular_componentribonucleoprotein complex
LT0003735molecular_functionstructural constituent of ribosome
LT0005840cellular_componentribosome
LT0006412biological_processtranslation
LT1990904cellular_componentribonucleoprotein complex
LU0002181biological_processcytoplasmic translation
LU0003723molecular_functionRNA binding
LU0003735molecular_functionstructural constituent of ribosome
LU0005840cellular_componentribosome
LU0006412biological_processtranslation
LU1990904cellular_componentribonucleoprotein complex
LV0003735molecular_functionstructural constituent of ribosome
LV0005840cellular_componentribosome
LV0006412biological_processtranslation
LV0022625cellular_componentcytosolic large ribosomal subunit
LV0070180molecular_functionlarge ribosomal subunit rRNA binding
LV1990904cellular_componentribonucleoprotein complex
LX0003735molecular_functionstructural constituent of ribosome
LX0005840cellular_componentribosome
LX0006412biological_processtranslation
LX0019843molecular_functionrRNA binding
LX1990904cellular_componentribonucleoprotein complex
LY0003723molecular_functionRNA binding
LY0003735molecular_functionstructural constituent of ribosome
LY0005840cellular_componentribosome
LY0006412biological_processtranslation
LY0015934cellular_componentlarge ribosomal subunit
LY1990904cellular_componentribonucleoprotein complex
LZ0003735molecular_functionstructural constituent of ribosome
LZ0005840cellular_componentribosome
LZ0006412biological_processtranslation
LZ1990904cellular_componentribonucleoprotein complex
Lc0003723molecular_functionRNA binding
Lc0003735molecular_functionstructural constituent of ribosome
Lc0005840cellular_componentribosome
Lc0022625cellular_componentcytosolic large ribosomal subunit
Lc1990904cellular_componentribonucleoprotein complex
Ld0002181biological_processcytoplasmic translation
Ld0003735molecular_functionstructural constituent of ribosome
Ld0005840cellular_componentribosome
Ld0006412biological_processtranslation
Ld0022625cellular_componentcytosolic large ribosomal subunit
Ld1990904cellular_componentribonucleoprotein complex
Le0003735molecular_functionstructural constituent of ribosome
Le0005840cellular_componentribosome
Le0006412biological_processtranslation
Le0022625cellular_componentcytosolic large ribosomal subunit
Le1990904cellular_componentribonucleoprotein complex
Lf0003735molecular_functionstructural constituent of ribosome
Lf0005840cellular_componentribosome
Lf0006412biological_processtranslation
Lf1990904cellular_componentribonucleoprotein complex
Lg0003735molecular_functionstructural constituent of ribosome
Lg0005840cellular_componentribosome
Lg0006412biological_processtranslation
Lg1990904cellular_componentribonucleoprotein complex
Lh0003735molecular_functionstructural constituent of ribosome
Lh0004576molecular_functionoligosaccharyl transferase activity
Lh0004579molecular_functiondolichyl-diphosphooligosaccharide-protein glycotransferase activity
Lh0005840cellular_componentribosome
Lh0006412biological_processtranslation
Lh0006486biological_processprotein glycosylation
Lh0012505cellular_componentendomembrane system
Lh0016020cellular_componentmembrane
Lh0016757molecular_functionglycosyltransferase activity
Lh0018279biological_processprotein N-linked glycosylation via asparagine
Lh0043687biological_processpost-translational protein modification
Lh0046872molecular_functionmetal ion binding
Lh1990904cellular_componentribonucleoprotein complex
Li0003735molecular_functionstructural constituent of ribosome
Li0005840cellular_componentribosome
Li0006412biological_processtranslation
Li1990904cellular_componentribonucleoprotein complex
Lj0003723molecular_functionRNA binding
Lj0003735molecular_functionstructural constituent of ribosome
Lj0005840cellular_componentribosome
Lj0006412biological_processtranslation
Lj0019843molecular_functionrRNA binding
Lj0022625cellular_componentcytosolic large ribosomal subunit
Lj0046872molecular_functionmetal ion binding
Lj1990904cellular_componentribonucleoprotein complex
Lk0003735molecular_functionstructural constituent of ribosome
Lk0005840cellular_componentribosome
Lk0006412biological_processtranslation
Ll0003735molecular_functionstructural constituent of ribosome
Ll0005840cellular_componentribosome
Ll0006412biological_processtranslation
Ll0022625cellular_componentcytosolic large ribosomal subunit
Ll1990904cellular_componentribonucleoprotein complex
Lq0003723molecular_functionRNA binding
Lq0003735molecular_functionstructural constituent of ribosome
Lq0005840cellular_componentribosome
Lq0006412biological_processtranslation
Lq0015934cellular_componentlarge ribosomal subunit
Lq1990904cellular_componentribonucleoprotein complex
Functional Information from PROSITE/UniProt
site_idPS00039
Number of Residues9
DetailsDEAD_ATP_HELICASE DEAD-box subfamily ATP-dependent helicases signature. IIDEADRiL
ChainResidueDetails
CEILE262-LEU270

site_idPS00049
Number of Residues27
DetailsRIBOSOMAL_L14 Ribosomal protein L14 signature. AVIVrqakpwkrf.DGvflyFedNagVI
ChainResidueDetails
LVALA78-ILE104

site_idPS00217
Number of Residues26
DetailsSUGAR_TRANSPORT_2 Sugar transport proteins signature 2. VeGVKeGNegkvvrkIadQevapdqK
ChainResidueDetails
CLVAL503-LYS528

site_idPS00359
Number of Residues16
DetailsRIBOSOMAL_L11 Ribosomal protein L11 signature. KeIlGTafSVGcQVdG
ChainResidueDetails
LKLYS130-GLY145

site_idPS00464
Number of Residues25
DetailsRIBOSOMAL_L22 Ribosomal protein L22 signature. RrrTyRAhGRinpymsnpCHIELiL
ChainResidueDetails
LPARG126-LEU150

site_idPS00474
Number of Residues24
DetailsRIBOSOMAL_L3 Ribosomal protein L3 signature. FekdemiDviAvTkGHGfvGvtaR
ChainResidueDetails
LBPHE210-ARG233

site_idPS00526
Number of Residues20
DetailsRIBOSOMAL_L19E Ribosomal protein L19e signature. QKRLaAsvlgCGegkVWLDP
ChainResidueDetails
LRGLN7-PRO26

site_idPS00678
Number of Residues15
DetailsWD_REPEATS_1 Trp-Asp (WD) repeats signature. VLSAsyDgLLRIWNA
ChainResidueDetails
CDVAL146-ALA160
CDLEU404-LEU418
CCLEU468-LEU482

site_idPS00700
Number of Residues22
DetailsRIBOSOMAL_L6_2 Ribosomal protein L6 signature 2. QickVrnKdiRkFlDGIYVseK
ChainResidueDetails
LHGLN165-LYS186

site_idPS00709
Number of Residues25
DetailsRIBOSOMAL_L30E_1 Ribosomal protein L30e signature 1. SgkvvlGyRstLKalRsGkaKlILI
ChainResidueDetails
LcSER23-ILE47

site_idPS00783
Number of Residues24
DetailsRIBOSOMAL_L13 Ribosomal protein L13 signature. VRGMIPhktarGAaalerLkVFeG
ChainResidueDetails
LOVAL86-GLY109

site_idPS00939
Number of Residues27
DetailsRIBOSOMAL_L1E Ribosomal protein L1e signature. NqgqKrfATaSALaASAvapllmaRGH
ChainResidueDetails
LCASN115-HIS141

site_idPS00993
Number of Residues21
DetailsRIBOSOMAL_L30E_2 Ribosomal protein L30e signature 2. ELGTacGKlfrcstMaIlDaG
ChainResidueDetails
LcGLU79-GLY99

site_idPS01077
Number of Residues20
DetailsRIBOSOMAL_L37E Ribosomal protein L37e signature. GTsSfGkRhnkt.HglCrRCG
ChainResidueDetails
LjGLY4-GLY23

site_idPS01082
Number of Residues18
DetailsRIBOSOMAL_L7AE Ribosomal protein L7Ae signature. CrkmgIPYaiIkGKarLG
ChainResidueDetails
LGCYS173-GLY190

site_idPS01104
Number of Residues15
DetailsRIBOSOMAL_L13E Ribosomal protein L13e signature. RlGRGFTLeELkaaG
ChainResidueDetails
LLARG70-GLY84

site_idPS01105
Number of Residues22
DetailsRIBOSOMAL_L35AE Ribosomal protein L35Ae signature. GKItRpHGnsGvVrAkFthpLP
ChainResidueDetails
LfGLY71-PRO92

site_idPS01106
Number of Residues18
DetailsRIBOSOMAL_L18E Ribosomal protein L18e signature. RrLfmSRinRPpVSLsRI
ChainResidueDetails
LQARG78-ILE95

site_idPS01107
Number of Residues12
DetailsRIBOSOMAL_L27E Ribosomal protein L27e signature. GKNrWFFtpLRF
ChainResidueDetails
LZGLY124-PHE135

site_idPS01144
Number of Residues15
DetailsRIBOSOMAL_L31E Ribosomal protein L31e signature. VRLDpqLNkKvWeQG
ChainResidueDetails
LdVAL57-GLY71

site_idPS01145
Number of Residues14
DetailsRIBOSOMAL_L34E Ribosomal protein L34e signature. TtSnRtrviKTPGG
ChainResidueDetails
LgTHR16-GLY29

site_idPS01153
Number of Residues12
DetailsNOL1_NOP2_SUN NOL1/NOP2/sun family signature. FDRVLlDAPCSG
ChainResidueDetails
CPPHE450-GLY461

site_idPS01170
Number of Residues19
DetailsRIBOSOMAL_L6E Ribosomal protein L6e signature. NgvPLRRvnarYVIATSv.K
ChainResidueDetails
LEASN90-LYS108

site_idPS01171
Number of Residues26
DetailsRIBOSOMAL_L21E Ribosomal protein L21e signature. GDiVdikvngavqk.GmpHkfYhGkTG
ChainResidueDetails
LTGLY37-GLY62

site_idPS01190
Number of Residues11
DetailsRIBOSOMAL_L36E Ribosomal protein L36e signature. PYERRvIELLR
ChainResidueDetails
LiPRO61-ARG71

site_idPS01194
Number of Residues24
DetailsRIBOSOMAL_L15E Ribosomal protein L15e signature. DKARrLGYkAkqGYVIYRvRVrRG
ChainResidueDetails
LNASP46-GLY69

site_idPS01199
Number of Residues20
DetailsRIBOSOMAL_L1 Ribosomal protein L1 signature. IkqIprlLGpgLSKAGkFPT
ChainResidueDetails
LqILE117-THR136

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues7
DetailsBINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU01047
ChainResidueDetails
CHGLY173
CHSER180
CHPHE198
CHTHR200
CHASP219
CHASN287
CHSER320

227111

PDB entries from 2024-11-06

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