8I5M
Rat Kir4.1 in complex with PIP2
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0005242 | molecular_function | inward rectifier potassium channel activity |
A | 0006813 | biological_process | potassium ion transport |
A | 0016020 | cellular_component | membrane |
B | 0005242 | molecular_function | inward rectifier potassium channel activity |
B | 0006813 | biological_process | potassium ion transport |
B | 0016020 | cellular_component | membrane |
C | 0005242 | molecular_function | inward rectifier potassium channel activity |
C | 0006813 | biological_process | potassium ion transport |
C | 0016020 | cellular_component | membrane |
D | 0005242 | molecular_function | inward rectifier potassium channel activity |
D | 0006813 | biological_process | potassium ion transport |
D | 0016020 | cellular_component | membrane |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 96 |
Details | TRANSMEM: Helical; Name=M1 => ECO:0000250 |
Chain | Residue | Details |
A | ARG65-VAL89 | |
B | ARG65-VAL89 | |
C | ARG65-VAL89 | |
D | ARG65-VAL89 |
site_id | SWS_FT_FI2 |
Number of Residues | 128 |
Details | TOPO_DOM: Extracellular => ECO:0000250 |
Chain | Residue | Details |
A | ALA90-THR114 | |
A | ARG134-LEU142 | |
B | ALA90-THR114 | |
B | ARG134-LEU142 | |
C | ALA90-THR114 | |
C | ARG134-LEU142 | |
D | ALA90-THR114 | |
D | ARG134-LEU142 |
site_id | SWS_FT_FI3 |
Number of Residues | 44 |
Details | INTRAMEM: Helical; Pore-forming; Name=H5 => ECO:0000250 |
Chain | Residue | Details |
A | LEU115-GLN126 | |
B | LEU115-GLN126 | |
C | LEU115-GLN126 | |
D | LEU115-GLN126 |
site_id | SWS_FT_FI4 |
Number of Residues | 24 |
Details | INTRAMEM: Pore-forming => ECO:0000250 |
Chain | Residue | Details |
A | THR127-PHE133 | |
B | THR127-PHE133 | |
C | THR127-PHE133 | |
D | THR127-PHE133 |
site_id | SWS_FT_FI5 |
Number of Residues | 84 |
Details | TRANSMEM: Helical; Name=M2 => ECO:0000250 |
Chain | Residue | Details |
A | ALA143-THR164 | |
B | ALA143-THR164 | |
C | ALA143-THR164 | |
D | ALA143-THR164 |
site_id | SWS_FT_FI6 |
Number of Residues | 4 |
Details | BINDING: BINDING => ECO:0000255 |
Chain | Residue | Details |
A | GLY210 | |
B | GLY210 | |
C | GLY210 | |
D | GLY210 |
site_id | SWS_FT_FI7 |
Number of Residues | 4 |
Details | SITE: Role in the control of polyamine-mediated channel gating and in the blocking by intracellular magnesium => ECO:0000250 |
Chain | Residue | Details |
A | GLU158 | |
B | GLU158 | |
C | GLU158 | |
D | GLU158 |