8I5M
Rat Kir4.1 in complex with PIP2
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005242 | molecular_function | inward rectifier potassium channel activity |
| A | 0006813 | biological_process | potassium ion transport |
| A | 0016020 | cellular_component | membrane |
| B | 0005242 | molecular_function | inward rectifier potassium channel activity |
| B | 0006813 | biological_process | potassium ion transport |
| B | 0016020 | cellular_component | membrane |
| C | 0005242 | molecular_function | inward rectifier potassium channel activity |
| C | 0006813 | biological_process | potassium ion transport |
| C | 0016020 | cellular_component | membrane |
| D | 0005242 | molecular_function | inward rectifier potassium channel activity |
| D | 0006813 | biological_process | potassium ion transport |
| D | 0016020 | cellular_component | membrane |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 104 |
| Details | Transmembrane: {"description":"Helical; Name=M1","evidences":[{"source":"PubMed","id":"38355723","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8I5M","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 132 |
| Details | Topological domain: {"description":"Extracellular","evidences":[{"source":"PubMed","id":"38355723","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"8I5M","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 64 |
| Details | Intramembrane: {"description":"Discontinuously helical; Pore-forming","evidences":[{"source":"PubMed","id":"38355723","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8I5M","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 100 |
| Details | Transmembrane: {"description":"Helical; Name=M2","evidences":[{"source":"PubMed","id":"38355723","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8I5M","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 20 |
| Details | Motif: {"description":"Selectivity filter","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"38355723","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8I5M","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 28 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 4 |
| Details | Site: {"description":"Role in the control of polyamine-mediated channel gating and in the blocking by intracellular magnesium","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
