8I1U

Human TRiC-PhLP2A complex in the closed state

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000242	cellular_component	pericentriolar material
A	0000792	cellular_component	heterochromatin
A	0001669	cellular_component	acrosomal vesicle
A	0002199	cellular_component	zona pellucida receptor complex
A	0003723	molecular_function	RNA binding
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005794	cellular_component	Golgi apparatus
A	0005813	cellular_component	centrosome
A	0005815	cellular_component	microtubule organizing center
A	0005829	cellular_component	cytosol
A	0005832	cellular_component	chaperonin-containing T-complex
A	0005856	cellular_component	cytoskeleton
A	0005874	cellular_component	microtubule
A	0006457	biological_process	protein folding
A	0007021	biological_process	tubulin complex assembly
A	0007339	biological_process	binding of sperm to zona pellucida
A	0031625	molecular_function	ubiquitin protein ligase binding
A	0032212	biological_process	positive regulation of telomere maintenance via telomerase
A	0044183	molecular_function	protein folding chaperone
A	0044297	cellular_component	cell body
A	0050821	biological_process	protein stabilization
A	0051082	molecular_function	unfolded protein binding
A	0051973	biological_process	positive regulation of telomerase activity
A	0061077	biological_process	chaperone-mediated protein folding
A	0070062	cellular_component	extracellular exosome
A	0090666	biological_process	scaRNA localization to Cajal body
A	1904851	biological_process	positive regulation of establishment of protein localization to telomere
A	1904871	biological_process	positive regulation of protein localization to Cajal body
A	1904874	biological_process	positive regulation of telomerase RNA localization to Cajal body
B	0002199	cellular_component	zona pellucida receptor complex
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005576	cellular_component	extracellular region
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0005832	cellular_component	chaperonin-containing T-complex
B	0005874	cellular_component	microtubule
B	0006457	biological_process	protein folding
B	0007339	biological_process	binding of sperm to zona pellucida
B	0031625	molecular_function	ubiquitin protein ligase binding
B	0032212	biological_process	positive regulation of telomere maintenance via telomerase
B	0035578	cellular_component	azurophil granule lumen
B	0044183	molecular_function	protein folding chaperone
B	0044297	cellular_component	cell body
B	0050821	biological_process	protein stabilization
B	0051082	molecular_function	unfolded protein binding
B	0051086	biological_process	chaperone mediated protein folding independent of cofactor
B	0051131	biological_process	chaperone-mediated protein complex assembly
B	0051973	biological_process	positive regulation of telomerase activity
B	0061077	biological_process	chaperone-mediated protein folding
B	0070062	cellular_component	extracellular exosome
B	0090666	biological_process	scaRNA localization to Cajal body
B	1904851	biological_process	positive regulation of establishment of protein localization to telomere
B	1904871	biological_process	positive regulation of protein localization to Cajal body
B	1904874	biological_process	positive regulation of telomerase RNA localization to Cajal body
C	0002199	cellular_component	zona pellucida receptor complex
C	0003723	molecular_function	RNA binding
C	0005515	molecular_function	protein binding
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0005832	cellular_component	chaperonin-containing T-complex
C	0005856	cellular_component	cytoskeleton
C	0005874	cellular_component	microtubule
C	0006457	biological_process	protein folding
C	0007339	biological_process	binding of sperm to zona pellucida
C	0032212	biological_process	positive regulation of telomere maintenance via telomerase
C	0044183	molecular_function	protein folding chaperone
C	0044297	cellular_component	cell body
C	0050821	biological_process	protein stabilization
C	0051082	molecular_function	unfolded protein binding
C	0061077	biological_process	chaperone-mediated protein folding
C	0070062	cellular_component	extracellular exosome
C	1904851	biological_process	positive regulation of establishment of protein localization to telomere
C	1904871	biological_process	positive regulation of protein localization to Cajal body
C	1904874	biological_process	positive regulation of telomerase RNA localization to Cajal body
D	0002199	cellular_component	zona pellucida receptor complex
D	0003723	molecular_function	RNA binding
D	0005515	molecular_function	protein binding
D	0005524	molecular_function	ATP binding
D	0005654	cellular_component	nucleoplasm
D	0005737	cellular_component	cytoplasm
D	0005813	cellular_component	centrosome
D	0005829	cellular_component	cytosol
D	0005832	cellular_component	chaperonin-containing T-complex
D	0005856	cellular_component	cytoskeleton
D	0005874	cellular_component	microtubule
D	0006457	biological_process	protein folding
D	0007339	biological_process	binding of sperm to zona pellucida
D	0032212	biological_process	positive regulation of telomere maintenance via telomerase
D	0042470	cellular_component	melanosome
D	0042995	cellular_component	cell projection
D	0044183	molecular_function	protein folding chaperone
D	0044297	cellular_component	cell body
D	0050821	biological_process	protein stabilization
D	0051082	molecular_function	unfolded protein binding
D	0051973	biological_process	positive regulation of telomerase activity
D	0061077	biological_process	chaperone-mediated protein folding
D	0070062	cellular_component	extracellular exosome
D	0090666	biological_process	scaRNA localization to Cajal body
D	1904851	biological_process	positive regulation of establishment of protein localization to telomere
D	1904871	biological_process	positive regulation of protein localization to Cajal body
D	1904874	biological_process	positive regulation of telomerase RNA localization to Cajal body
E	0003730	molecular_function	mRNA 3'-UTR binding
E	0005515	molecular_function	protein binding
E	0005524	molecular_function	ATP binding
E	0005737	cellular_component	cytoplasm
E	0005813	cellular_component	centrosome
E	0005829	cellular_component	cytosol
E	0005832	cellular_component	chaperonin-containing T-complex
E	0005856	cellular_component	cytoskeleton
E	0005874	cellular_component	microtubule
E	0006457	biological_process	protein folding
E	0007339	biological_process	binding of sperm to zona pellucida
E	0009615	biological_process	response to virus
E	0031681	molecular_function	G-protein beta-subunit binding
E	0032212	biological_process	positive regulation of telomere maintenance via telomerase
E	0044183	molecular_function	protein folding chaperone
E	0044297	cellular_component	cell body
E	0048027	molecular_function	mRNA 5'-UTR binding
E	0048487	molecular_function	beta-tubulin binding
E	0050821	biological_process	protein stabilization
E	0051082	molecular_function	unfolded protein binding
E	0061077	biological_process	chaperone-mediated protein folding
E	0070062	cellular_component	extracellular exosome
E	1904851	biological_process	positive regulation of establishment of protein localization to telomere
E	1904871	biological_process	positive regulation of protein localization to Cajal body
E	1904874	biological_process	positive regulation of telomerase RNA localization to Cajal body
F	0003723	molecular_function	RNA binding
F	0005515	molecular_function	protein binding
F	0005524	molecular_function	ATP binding
F	0005737	cellular_component	cytoplasm
F	0005829	cellular_component	cytosol
F	0005832	cellular_component	chaperonin-containing T-complex
F	0005874	cellular_component	microtubule
F	0006457	biological_process	protein folding
F	0032212	biological_process	positive regulation of telomere maintenance via telomerase
F	0044183	molecular_function	protein folding chaperone
F	0050821	biological_process	protein stabilization
F	0051082	molecular_function	unfolded protein binding
F	0061077	biological_process	chaperone-mediated protein folding
F	0070062	cellular_component	extracellular exosome
F	0071987	molecular_function	WD40-repeat domain binding
F	1904851	biological_process	positive regulation of establishment of protein localization to telomere
F	1904871	biological_process	positive regulation of protein localization to Cajal body
F	1904874	biological_process	positive regulation of telomerase RNA localization to Cajal body
G	0005515	molecular_function	protein binding
G	0005524	molecular_function	ATP binding
G	0005737	cellular_component	cytoplasm
G	0005829	cellular_component	cytosol
G	0005832	cellular_component	chaperonin-containing T-complex
G	0005874	cellular_component	microtubule
G	0006457	biological_process	protein folding
G	0007339	biological_process	binding of sperm to zona pellucida
G	0032212	biological_process	positive regulation of telomere maintenance via telomerase
G	0044183	molecular_function	protein folding chaperone
G	0044297	cellular_component	cell body
G	0050821	biological_process	protein stabilization
G	0051082	molecular_function	unfolded protein binding
G	0061077	biological_process	chaperone-mediated protein folding
G	0070062	cellular_component	extracellular exosome
G	1904851	biological_process	positive regulation of establishment of protein localization to telomere
G	1904871	biological_process	positive regulation of protein localization to Cajal body
G	1904874	biological_process	positive regulation of telomerase RNA localization to Cajal body
H	0002199	cellular_component	zona pellucida receptor complex
H	0005515	molecular_function	protein binding
H	0005524	molecular_function	ATP binding
H	0005576	cellular_component	extracellular region
H	0005654	cellular_component	nucleoplasm
H	0005737	cellular_component	cytoplasm
H	0005813	cellular_component	centrosome
H	0005829	cellular_component	cytosol
H	0005832	cellular_component	chaperonin-containing T-complex
H	0005856	cellular_component	cytoskeleton
H	0005874	cellular_component	microtubule
H	0005929	cellular_component	cilium
H	0006457	biological_process	protein folding
H	0007339	biological_process	binding of sperm to zona pellucida
H	0032212	biological_process	positive regulation of telomere maintenance via telomerase
H	0034774	cellular_component	secretory granule lumen
H	0035578	cellular_component	azurophil granule lumen
H	0044183	molecular_function	protein folding chaperone
H	0044297	cellular_component	cell body
H	0045111	cellular_component	intermediate filament cytoskeleton
H	0045296	molecular_function	cadherin binding
H	0050821	biological_process	protein stabilization
H	0051082	molecular_function	unfolded protein binding
H	0061077	biological_process	chaperone-mediated protein folding
H	0070062	cellular_component	extracellular exosome
H	1904813	cellular_component	ficolin-1-rich granule lumen
H	1904851	biological_process	positive regulation of establishment of protein localization to telomere
H	1904871	biological_process	positive regulation of protein localization to Cajal body
H	1904874	biological_process	positive regulation of telomerase RNA localization to Cajal body
I	0000242	cellular_component	pericentriolar material
I	0000792	cellular_component	heterochromatin
I	0001669	cellular_component	acrosomal vesicle
I	0002199	cellular_component	zona pellucida receptor complex
I	0003723	molecular_function	RNA binding
I	0005515	molecular_function	protein binding
I	0005524	molecular_function	ATP binding
I	0005737	cellular_component	cytoplasm
I	0005794	cellular_component	Golgi apparatus
I	0005813	cellular_component	centrosome
I	0005815	cellular_component	microtubule organizing center
I	0005829	cellular_component	cytosol
I	0005832	cellular_component	chaperonin-containing T-complex
I	0005856	cellular_component	cytoskeleton
I	0005874	cellular_component	microtubule
I	0006457	biological_process	protein folding
I	0007021	biological_process	tubulin complex assembly
I	0007339	biological_process	binding of sperm to zona pellucida
I	0031625	molecular_function	ubiquitin protein ligase binding
I	0032212	biological_process	positive regulation of telomere maintenance via telomerase
I	0044183	molecular_function	protein folding chaperone
I	0044297	cellular_component	cell body
I	0050821	biological_process	protein stabilization
I	0051082	molecular_function	unfolded protein binding
I	0051973	biological_process	positive regulation of telomerase activity
I	0061077	biological_process	chaperone-mediated protein folding
I	0070062	cellular_component	extracellular exosome
I	0090666	biological_process	scaRNA localization to Cajal body
I	1904851	biological_process	positive regulation of establishment of protein localization to telomere
I	1904871	biological_process	positive regulation of protein localization to Cajal body
I	1904874	biological_process	positive regulation of telomerase RNA localization to Cajal body
J	0002199	cellular_component	zona pellucida receptor complex
J	0005515	molecular_function	protein binding
J	0005524	molecular_function	ATP binding
J	0005576	cellular_component	extracellular region
J	0005737	cellular_component	cytoplasm
J	0005829	cellular_component	cytosol
J	0005832	cellular_component	chaperonin-containing T-complex
J	0005874	cellular_component	microtubule
J	0006457	biological_process	protein folding
J	0007339	biological_process	binding of sperm to zona pellucida
J	0031625	molecular_function	ubiquitin protein ligase binding
J	0032212	biological_process	positive regulation of telomere maintenance via telomerase
J	0035578	cellular_component	azurophil granule lumen
J	0044183	molecular_function	protein folding chaperone
J	0044297	cellular_component	cell body
J	0050821	biological_process	protein stabilization
J	0051082	molecular_function	unfolded protein binding
J	0051086	biological_process	chaperone mediated protein folding independent of cofactor
J	0051131	biological_process	chaperone-mediated protein complex assembly
J	0051973	biological_process	positive regulation of telomerase activity
J	0061077	biological_process	chaperone-mediated protein folding
J	0070062	cellular_component	extracellular exosome
J	0090666	biological_process	scaRNA localization to Cajal body
J	1904851	biological_process	positive regulation of establishment of protein localization to telomere
J	1904871	biological_process	positive regulation of protein localization to Cajal body
J	1904874	biological_process	positive regulation of telomerase RNA localization to Cajal body
K	0002199	cellular_component	zona pellucida receptor complex
K	0003723	molecular_function	RNA binding
K	0005515	molecular_function	protein binding
K	0005524	molecular_function	ATP binding
K	0005737	cellular_component	cytoplasm
K	0005829	cellular_component	cytosol
K	0005832	cellular_component	chaperonin-containing T-complex
K	0005856	cellular_component	cytoskeleton
K	0005874	cellular_component	microtubule
K	0006457	biological_process	protein folding
K	0007339	biological_process	binding of sperm to zona pellucida
K	0032212	biological_process	positive regulation of telomere maintenance via telomerase
K	0044183	molecular_function	protein folding chaperone
K	0044297	cellular_component	cell body
K	0050821	biological_process	protein stabilization
K	0051082	molecular_function	unfolded protein binding
K	0061077	biological_process	chaperone-mediated protein folding
K	0070062	cellular_component	extracellular exosome
K	1904851	biological_process	positive regulation of establishment of protein localization to telomere
K	1904871	biological_process	positive regulation of protein localization to Cajal body
K	1904874	biological_process	positive regulation of telomerase RNA localization to Cajal body
L	0002199	cellular_component	zona pellucida receptor complex
L	0003723	molecular_function	RNA binding
L	0005515	molecular_function	protein binding
L	0005524	molecular_function	ATP binding
L	0005654	cellular_component	nucleoplasm
L	0005737	cellular_component	cytoplasm
L	0005813	cellular_component	centrosome
L	0005829	cellular_component	cytosol
L	0005832	cellular_component	chaperonin-containing T-complex
L	0005856	cellular_component	cytoskeleton
L	0005874	cellular_component	microtubule
L	0006457	biological_process	protein folding
L	0007339	biological_process	binding of sperm to zona pellucida
L	0032212	biological_process	positive regulation of telomere maintenance via telomerase
L	0042470	cellular_component	melanosome
L	0042995	cellular_component	cell projection
L	0044183	molecular_function	protein folding chaperone
L	0044297	cellular_component	cell body
L	0050821	biological_process	protein stabilization
L	0051082	molecular_function	unfolded protein binding
L	0051973	biological_process	positive regulation of telomerase activity
L	0061077	biological_process	chaperone-mediated protein folding
L	0070062	cellular_component	extracellular exosome
L	0090666	biological_process	scaRNA localization to Cajal body
L	1904851	biological_process	positive regulation of establishment of protein localization to telomere
L	1904871	biological_process	positive regulation of protein localization to Cajal body
L	1904874	biological_process	positive regulation of telomerase RNA localization to Cajal body
M	0003730	molecular_function	mRNA 3'-UTR binding
M	0005515	molecular_function	protein binding
M	0005524	molecular_function	ATP binding
M	0005737	cellular_component	cytoplasm
M	0005813	cellular_component	centrosome
M	0005829	cellular_component	cytosol
M	0005832	cellular_component	chaperonin-containing T-complex
M	0005856	cellular_component	cytoskeleton
M	0005874	cellular_component	microtubule
M	0006457	biological_process	protein folding
M	0007339	biological_process	binding of sperm to zona pellucida
M	0009615	biological_process	response to virus
M	0031681	molecular_function	G-protein beta-subunit binding
M	0032212	biological_process	positive regulation of telomere maintenance via telomerase
M	0044183	molecular_function	protein folding chaperone
M	0044297	cellular_component	cell body
M	0048027	molecular_function	mRNA 5'-UTR binding
M	0048487	molecular_function	beta-tubulin binding
M	0050821	biological_process	protein stabilization
M	0051082	molecular_function	unfolded protein binding
M	0061077	biological_process	chaperone-mediated protein folding
M	0070062	cellular_component	extracellular exosome
M	1904851	biological_process	positive regulation of establishment of protein localization to telomere
M	1904871	biological_process	positive regulation of protein localization to Cajal body
M	1904874	biological_process	positive regulation of telomerase RNA localization to Cajal body
N	0003723	molecular_function	RNA binding
N	0005515	molecular_function	protein binding
N	0005524	molecular_function	ATP binding
N	0005737	cellular_component	cytoplasm
N	0005829	cellular_component	cytosol
N	0005832	cellular_component	chaperonin-containing T-complex
N	0005874	cellular_component	microtubule
N	0006457	biological_process	protein folding
N	0032212	biological_process	positive regulation of telomere maintenance via telomerase
N	0044183	molecular_function	protein folding chaperone
N	0050821	biological_process	protein stabilization
N	0051082	molecular_function	unfolded protein binding
N	0061077	biological_process	chaperone-mediated protein folding
N	0070062	cellular_component	extracellular exosome
N	0071987	molecular_function	WD40-repeat domain binding
N	1904851	biological_process	positive regulation of establishment of protein localization to telomere
N	1904871	biological_process	positive regulation of protein localization to Cajal body
N	1904874	biological_process	positive regulation of telomerase RNA localization to Cajal body
O	0005515	molecular_function	protein binding
O	0005524	molecular_function	ATP binding
O	0005737	cellular_component	cytoplasm
O	0005829	cellular_component	cytosol
O	0005832	cellular_component	chaperonin-containing T-complex
O	0005874	cellular_component	microtubule
O	0006457	biological_process	protein folding
O	0007339	biological_process	binding of sperm to zona pellucida
O	0032212	biological_process	positive regulation of telomere maintenance via telomerase
O	0044183	molecular_function	protein folding chaperone
O	0044297	cellular_component	cell body
O	0050821	biological_process	protein stabilization
O	0051082	molecular_function	unfolded protein binding
O	0061077	biological_process	chaperone-mediated protein folding
O	0070062	cellular_component	extracellular exosome
O	1904851	biological_process	positive regulation of establishment of protein localization to telomere
O	1904871	biological_process	positive regulation of protein localization to Cajal body
O	1904874	biological_process	positive regulation of telomerase RNA localization to Cajal body
P	0002199	cellular_component	zona pellucida receptor complex
P	0005515	molecular_function	protein binding
P	0005524	molecular_function	ATP binding
P	0005576	cellular_component	extracellular region
P	0005654	cellular_component	nucleoplasm
P	0005737	cellular_component	cytoplasm
P	0005813	cellular_component	centrosome
P	0005829	cellular_component	cytosol
P	0005832	cellular_component	chaperonin-containing T-complex
P	0005856	cellular_component	cytoskeleton
P	0005874	cellular_component	microtubule
P	0005929	cellular_component	cilium
P	0006457	biological_process	protein folding
P	0007339	biological_process	binding of sperm to zona pellucida
P	0032212	biological_process	positive regulation of telomere maintenance via telomerase
P	0034774	cellular_component	secretory granule lumen
P	0035578	cellular_component	azurophil granule lumen
P	0044183	molecular_function	protein folding chaperone
P	0044297	cellular_component	cell body
P	0045111	cellular_component	intermediate filament cytoskeleton
P	0045296	molecular_function	cadherin binding
P	0050821	biological_process	protein stabilization
P	0051082	molecular_function	unfolded protein binding
P	0061077	biological_process	chaperone-mediated protein folding
P	0070062	cellular_component	extracellular exosome
P	1904813	cellular_component	ficolin-1-rich granule lumen
P	1904851	biological_process	positive regulation of establishment of protein localization to telomere
P	1904871	biological_process	positive regulation of protein localization to Cajal body
P	1904874	biological_process	positive regulation of telomerase RNA localization to Cajal body
Q	0001525	biological_process	angiogenesis
Q	0001938	biological_process	positive regulation of endothelial cell proliferation
Q	0005515	molecular_function	protein binding
Q	0005654	cellular_component	nucleoplasm
Q	0005737	cellular_component	cytoplasm
Q	0005783	cellular_component	endoplasmic reticulum
Q	0005829	cellular_component	cytosol
Q	0006457	biological_process	protein folding
Q	0006915	biological_process	apoptotic process
Q	0010628	biological_process	positive regulation of gene expression
Q	0030036	biological_process	actin cytoskeleton organization
Q	0032991	cellular_component	protein-containing complex
Q	0043184	molecular_function	vascular endothelial growth factor receptor 2 binding
Q	0044183	molecular_function	protein folding chaperone
Q	0045766	biological_process	positive regulation of angiogenesis
Q	0048471	cellular_component	perinuclear region of cytoplasm
Q	0050730	biological_process	regulation of peptidyl-tyrosine phosphorylation
Q	0050821	biological_process	protein stabilization
Q	0061077	biological_process	chaperone-mediated protein folding
Q	0097356	cellular_component	perinucleolar compartment
Q	1903645	biological_process	negative regulation of chaperone-mediated protein folding
Q	2000059	biological_process	negative regulation of ubiquitin-dependent protein catabolic process
R	0001525	biological_process	angiogenesis
R	0001938	biological_process	positive regulation of endothelial cell proliferation
R	0005515	molecular_function	protein binding
R	0005654	cellular_component	nucleoplasm
R	0005737	cellular_component	cytoplasm
R	0005783	cellular_component	endoplasmic reticulum
R	0005829	cellular_component	cytosol
R	0006457	biological_process	protein folding
R	0006915	biological_process	apoptotic process
R	0010628	biological_process	positive regulation of gene expression
R	0030036	biological_process	actin cytoskeleton organization
R	0032991	cellular_component	protein-containing complex
R	0043184	molecular_function	vascular endothelial growth factor receptor 2 binding
R	0044183	molecular_function	protein folding chaperone
R	0045766	biological_process	positive regulation of angiogenesis
R	0048471	cellular_component	perinuclear region of cytoplasm
R	0050730	biological_process	regulation of peptidyl-tyrosine phosphorylation
R	0050821	biological_process	protein stabilization
R	0061077	biological_process	chaperone-mediated protein folding
R	0097356	cellular_component	perinucleolar compartment
R	1903645	biological_process	negative regulation of chaperone-mediated protein folding
R	2000059	biological_process	negative regulation of ubiquitin-dependent protein catabolic process

Functional Information from PROSITE/UniProt

site_id	PS00107
Number of Residues	26
Details	PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. VGDGTTSVTVlAaellreaesl........IAKK

Chain	Residue	Details
B	VAL95-LYS120

---

site_id	PS00141
Number of Residues	12
Details	ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. AIADTGANVVVT

Chain	Residue	Details
H	ALA282-THR293

---

site_id	PS00750
Number of Residues	13
Details	TCP1_1 Chaperonins TCP-1 signature 1. RTnLGPkGtmKML

Chain	Residue	Details
F	ARG35-LEU47
H	ARG44-VAL56
E	ARG49-MET61
C	ARG38-LEU50
G	ARG37-ILE49
B	LYS40-LEU52
A	LYS33-LEU45
D	ARG49-ILE61

---

site_id	PS00751
Number of Residues	17
Details	TCP1_2 Chaperonins TCP-1 signature 2. LTKDGNVLLheMqIqHP

Chain	Residue	Details
F	LEU56-PRO72
H	VAL65-PRO81
E	VAL70-GLN86
C	MET59-PRO75
G	ILE58-PRO74
B	VAL63-PRO79
A	ILE54-PRO70
D	ILE70-PRO86

---

site_id	PS00995
Number of Residues	9
Details	TCP1_3 Chaperonins TCP-1 signature 3. QDdiTGDGT

Chain	Residue	Details
F	GLN84-THR92
H	GLN93-THR101
E	GLN98-THR106
C	GLN87-THR95
G	GLN86-THR94
B	GLN91-THR99
A	GLN82-THR90
D	GLN98-THR106

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	MOD_RES: N-acetylmethionine => ECO:0000269|PubMed:26059764

Chain	Residue	Details
Q	MET1
R	MET1

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
Q	SER43
R	SER43
O	LYS67
O	LYS320

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692

Chain	Residue	Details
Q	SER234
Q	SER236
R	SER234
R	SER236
N	LYS199
N	LYS365
N	LYS377
N	LYS388

---

site_id	SWS_FT_FI4
Number of Residues	10
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
H	SER162
P	SER537
M	LYS210
M	LYS214
M	LYS265
M	LYS275
M	LYS279
M	LYS392
H	SER213
H	SER269
H	SER317
H	SER537
P	SER162
P	SER213
P	SER269
P	SER317

---

site_id	SWS_FT_FI5
Number of Residues	6
Details	MOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861

Chain	Residue	Details
H	LYS318
H	LYS400
H	LYS466
P	LYS318
P	LYS400
P	LYS466

---

site_id	SWS_FT_FI6
Number of Residues	2
Details	MOD_RES: Phosphotyrosine => ECO:0007744|PubMed:15592455

Chain	Residue	Details
H	TYR505
P	TYR505

---

site_id	SWS_FT_FI7
Number of Residues	6
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733

Chain	Residue	Details
H	LYS224
H	LYS254
H	LYS260
P	LYS224
P	LYS254
P	LYS260

---

site_id	SWS_FT_FI8
Number of Residues	4
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:25755297, ECO:0007744|PubMed:28112733

Chain	Residue	Details
C	THR430
H	LYS539
K	THR430
P	LYS539

---

site_id	SWS_FT_FI9
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1) => ECO:0007744|PubMed:25114211

Chain	Residue	Details
H	LYS459
P	LYS459
C	LYS249
K	LYS15
K	LYS248
K	LYS249

---

site_id	SWS_FT_FI10
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:25218447, ECO:0007744|PubMed:25755297, ECO:0007744|PubMed:28112733

Chain	Residue	Details
H	LYS534
P	LYS534
K	LYS381

---