8HYJ

A cryo-EM structure of KTF1-bound polymerase V transcription elongation complex

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000418	cellular_component	RNA polymerase IV complex
A	0000419	cellular_component	RNA polymerase V complex
A	0000428	cellular_component	DNA-directed RNA polymerase complex
A	0003677	molecular_function	DNA binding
A	0003899	molecular_function	DNA-directed RNA polymerase activity
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005730	cellular_component	nucleolus
A	0006351	biological_process	DNA-templated transcription
A	0016604	cellular_component	nuclear body
A	0016740	molecular_function	transferase activity
A	0016779	molecular_function	nucleotidyltransferase activity
A	0030422	biological_process	siRNA processing
A	0030880	cellular_component	RNA polymerase complex
A	0034062	molecular_function	5'-3' RNA polymerase activity
A	0035194	biological_process	regulatory ncRNA-mediated post-transcriptional gene silencing
A	0046872	molecular_function	metal ion binding
A	0050832	biological_process	defense response to fungus
B	0000418	cellular_component	RNA polymerase IV complex
B	0000419	cellular_component	RNA polymerase V complex
B	0000428	cellular_component	DNA-directed RNA polymerase complex
B	0000792	cellular_component	heterochromatin
B	0003677	molecular_function	DNA binding
B	0003899	molecular_function	DNA-directed RNA polymerase activity
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005665	cellular_component	RNA polymerase II, core complex
B	0006351	biological_process	DNA-templated transcription
B	0008270	molecular_function	zinc ion binding
B	0016740	molecular_function	transferase activity
B	0016779	molecular_function	nucleotidyltransferase activity
B	0030422	biological_process	siRNA processing
B	0030880	cellular_component	RNA polymerase complex
B	0031047	biological_process	regulatory ncRNA-mediated gene silencing
B	0031507	biological_process	heterochromatin formation
B	0032549	molecular_function	ribonucleoside binding
B	0034062	molecular_function	5'-3' RNA polymerase activity
B	0035194	biological_process	regulatory ncRNA-mediated post-transcriptional gene silencing
B	0046872	molecular_function	metal ion binding
B	0050776	biological_process	regulation of immune response
B	0050832	biological_process	defense response to fungus
B	0080188	biological_process	gene silencing by siRNA-directed DNA methylation
B	0141007	biological_process	transposable element silencing by siRNA-mediated heterochromatin formation
C	0000418	cellular_component	RNA polymerase IV complex
C	0000419	cellular_component	RNA polymerase V complex
C	0000428	cellular_component	DNA-directed RNA polymerase complex
C	0003677	molecular_function	DNA binding
C	0003899	molecular_function	DNA-directed RNA polymerase activity
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005665	cellular_component	RNA polymerase II, core complex
C	0006351	biological_process	DNA-templated transcription
C	0006366	biological_process	transcription by RNA polymerase II
C	0046983	molecular_function	protein dimerization activity
D	0000166	molecular_function	nucleotide binding
D	0000418	cellular_component	RNA polymerase IV complex
D	0000419	cellular_component	RNA polymerase V complex
D	0005634	cellular_component	nucleus
D	0006352	biological_process	DNA-templated transcription initiation
D	0030422	biological_process	siRNA processing
D	0030880	cellular_component	RNA polymerase complex
E	0000419	cellular_component	RNA polymerase V complex
E	0003677	molecular_function	DNA binding
E	0003899	molecular_function	DNA-directed RNA polymerase activity
E	0005515	molecular_function	protein binding
E	0005634	cellular_component	nucleus
E	0006351	biological_process	DNA-templated transcription
E	0006362	biological_process	transcription elongation by RNA polymerase I
E	0006366	biological_process	transcription by RNA polymerase II
E	0042797	biological_process	tRNA transcription by RNA polymerase III
E	0055029	cellular_component	nuclear DNA-directed RNA polymerase complex
F	0000418	cellular_component	RNA polymerase IV complex
F	0000419	cellular_component	RNA polymerase V complex
F	0000428	cellular_component	DNA-directed RNA polymerase complex
F	0003677	molecular_function	DNA binding
F	0003899	molecular_function	DNA-directed RNA polymerase activity
F	0005515	molecular_function	protein binding
F	0005634	cellular_component	nucleus
F	0005665	cellular_component	RNA polymerase II, core complex
F	0005666	cellular_component	RNA polymerase III complex
F	0005736	cellular_component	RNA polymerase I complex
F	0006351	biological_process	DNA-templated transcription
F	0006360	biological_process	transcription by RNA polymerase I
F	0006366	biological_process	transcription by RNA polymerase II
F	0042797	biological_process	tRNA transcription by RNA polymerase III
G	0000419	cellular_component	RNA polymerase V complex
G	0000428	cellular_component	DNA-directed RNA polymerase complex
G	0003697	molecular_function	single-stranded DNA binding
G	0003727	molecular_function	single-stranded RNA binding
G	0005634	cellular_component	nucleus
G	0006351	biological_process	DNA-templated transcription
G	0006352	biological_process	DNA-templated transcription initiation
G	0055029	cellular_component	nuclear DNA-directed RNA polymerase complex
H	0000419	cellular_component	RNA polymerase V complex
H	0003899	molecular_function	DNA-directed RNA polymerase activity
H	0005634	cellular_component	nucleus
H	0005665	cellular_component	RNA polymerase II, core complex
H	0005666	cellular_component	RNA polymerase III complex
H	0005736	cellular_component	RNA polymerase I complex
H	0006351	biological_process	DNA-templated transcription
I	0000419	cellular_component	RNA polymerase V complex
I	0000428	cellular_component	DNA-directed RNA polymerase complex
I	0001193	biological_process	maintenance of transcriptional fidelity during transcription elongation by RNA polymerase II
I	0003676	molecular_function	nucleic acid binding
I	0003899	molecular_function	DNA-directed RNA polymerase activity
I	0005515	molecular_function	protein binding
I	0005634	cellular_component	nucleus
I	0005665	cellular_component	RNA polymerase II, core complex
I	0005730	cellular_component	nucleolus
I	0006283	biological_process	transcription-coupled nucleotide-excision repair
I	0006351	biological_process	DNA-templated transcription
I	0006367	biological_process	transcription initiation at RNA polymerase II promoter
I	0008270	molecular_function	zinc ion binding
I	0046872	molecular_function	metal ion binding
J	0000418	cellular_component	RNA polymerase IV complex
J	0000419	cellular_component	RNA polymerase V complex
J	0000428	cellular_component	DNA-directed RNA polymerase complex
J	0003677	molecular_function	DNA binding
J	0003899	molecular_function	DNA-directed RNA polymerase activity
J	0005634	cellular_component	nucleus
J	0005665	cellular_component	RNA polymerase II, core complex
J	0005666	cellular_component	RNA polymerase III complex
J	0005736	cellular_component	RNA polymerase I complex
J	0006351	biological_process	DNA-templated transcription
J	0006360	biological_process	transcription by RNA polymerase I
J	0006366	biological_process	transcription by RNA polymerase II
J	0008270	molecular_function	zinc ion binding
J	0042797	biological_process	tRNA transcription by RNA polymerase III
J	0046872	molecular_function	metal ion binding
K	0000418	cellular_component	RNA polymerase IV complex
K	0000419	cellular_component	RNA polymerase V complex
K	0000428	cellular_component	DNA-directed RNA polymerase complex
K	0003677	molecular_function	DNA binding
K	0003899	molecular_function	DNA-directed RNA polymerase activity
K	0005634	cellular_component	nucleus
K	0005665	cellular_component	RNA polymerase II, core complex
K	0006351	biological_process	DNA-templated transcription
K	0006366	biological_process	transcription by RNA polymerase II
K	0046983	molecular_function	protein dimerization activity
L	0000418	cellular_component	RNA polymerase IV complex
L	0000428	cellular_component	DNA-directed RNA polymerase complex
L	0003677	molecular_function	DNA binding
L	0003899	molecular_function	DNA-directed RNA polymerase activity
L	0005634	cellular_component	nucleus
L	0005665	cellular_component	RNA polymerase II, core complex
L	0005666	cellular_component	RNA polymerase III complex
L	0005736	cellular_component	RNA polymerase I complex
L	0006351	biological_process	DNA-templated transcription
L	0008270	molecular_function	zinc ion binding
L	0046872	molecular_function	metal ion binding
W	0003677	molecular_function	DNA binding
W	0003682	molecular_function	chromatin binding
W	0003723	molecular_function	RNA binding
W	0003729	molecular_function	mRNA binding
W	0005515	molecular_function	protein binding
W	0005634	cellular_component	nucleus
W	0005654	cellular_component	nucleoplasm
W	0006354	biological_process	DNA-templated transcription elongation
W	0006357	biological_process	regulation of transcription by RNA polymerase II
W	0006368	biological_process	transcription elongation by RNA polymerase II
W	0030422	biological_process	siRNA processing
W	0031047	biological_process	regulatory ncRNA-mediated gene silencing
W	0031507	biological_process	heterochromatin formation
W	0032044	cellular_component	DSIF complex
W	0032784	biological_process	regulation of DNA-templated transcription elongation
W	0080188	biological_process	gene silencing by siRNA-directed DNA methylation

Functional Information from PROSITE/UniProt

site_id	PS00446
Number of Residues	41
Details	RNA_POL_D_30KD RNA polymerases D / 30 to 40 Kd subunits signature. NALRRvmisevptmAihlVkievNsSvlnDEfIAqRLSLIP

Chain	Residue	Details
C	ASN35-PRO75

---

site_id	PS01030
Number of Residues	27
Details	RNA_POL_M_15KD RNA polymerases M / 15 Kd subunits signature. FCRECNNILypkedkeqkillyaCrnC

Chain	Residue	Details
I	PHE6-CYS32

---

site_id	PS01111
Number of Residues	15
Details	RNA_POL_K_14KD RNA polymerases K / 14 to 18 Kd subunits signature. TkYErARiLGtRAlQ

Chain	Residue	Details
F	THR66-GLN80

---

site_id	PS01112
Number of Residues	10
Details	RNA_POL_N_8KD RNA polymerases N / 8 Kd subunits signature. IIPVrCFTCG

Chain	Residue	Details
J	ILE2-GLY11

---

site_id	PS01154
Number of Residues	32
Details	RNA_POL_L_13KD RNA polymerases L / 13 to 16 Kd subunits signature. VerEdHTIgNiVrmqLhrdenVlfagYqlpHP

Chain	Residue	Details
K	VAL35-PRO66

---

site_id	PS01166
Number of Residues	13
Details	RNA_POL_BETA RNA polymerases beta chain signature. GdKFSSmHGQKGV

Chain	Residue	Details
B	GLY911-VAL923

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Repeat: {"description":"1","evidences":[{"source":"PubMed","id":"20338883","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	12
Details	Region: {"description":"Bridging helix","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	9
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P04050","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	13
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	41
Details	Zinc finger: {"description":"TFIIS-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00472","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10145","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00472","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---