Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

8HKU

Cryo-EM Structures and Translocation Mechanism of Crenarchaeota Ribosome

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
AL1P	0000049	molecular_function	tRNA binding
AL1P	0003723	molecular_function	RNA binding
AL1P	0003735	molecular_function	structural constituent of ribosome
AL1P	0005840	cellular_component	ribosome
AL1P	0006412	biological_process	translation
AL1P	0006417	biological_process	regulation of translation
AL1P	0015934	cellular_component	large ribosomal subunit
AL1P	0019843	molecular_function	rRNA binding
AL1P	1990904	cellular_component	ribonucleoprotein complex
AL2P	0002181	biological_process	cytoplasmic translation
AL2P	0003723	molecular_function	RNA binding
AL2P	0003735	molecular_function	structural constituent of ribosome
AL2P	0005840	cellular_component	ribosome
AL2P	0006412	biological_process	translation
AL2P	0015934	cellular_component	large ribosomal subunit
AL2P	0019843	molecular_function	rRNA binding
AL2P	0022625	cellular_component	cytosolic large ribosomal subunit
AL2P	0022626	cellular_component	cytosolic ribosome
AL2P	1990904	cellular_component	ribonucleoprotein complex
AL3P	0003723	molecular_function	RNA binding
AL3P	0003735	molecular_function	structural constituent of ribosome
AL3P	0005840	cellular_component	ribosome
AL3P	0006412	biological_process	translation
AL3P	0019843	molecular_function	rRNA binding
AL3P	0022625	cellular_component	cytosolic large ribosomal subunit
AL3P	1990904	cellular_component	ribonucleoprotein complex
AL4P	0003735	molecular_function	structural constituent of ribosome
AL4P	0005840	cellular_component	ribosome
AL4P	0006412	biological_process	translation
AL4P	0019843	molecular_function	rRNA binding
AL4P	1990904	cellular_component	ribonucleoprotein complex
AL5P	0000049	molecular_function	tRNA binding
AL5P	0003735	molecular_function	structural constituent of ribosome
AL5P	0005840	cellular_component	ribosome
AL5P	0006412	biological_process	translation
AL5P	0019843	molecular_function	rRNA binding
AL5P	1990904	cellular_component	ribonucleoprotein complex
AL6P	0002181	biological_process	cytoplasmic translation
AL6P	0003735	molecular_function	structural constituent of ribosome
AL6P	0005840	cellular_component	ribosome
AL6P	0006412	biological_process	translation
AL6P	0019843	molecular_function	rRNA binding
AL6P	0022625	cellular_component	cytosolic large ribosomal subunit
AL6P	1990904	cellular_component	ribonucleoprotein complex
ALX0	0003735	molecular_function	structural constituent of ribosome
ALX0	0005840	cellular_component	ribosome
ALX0	0006412	biological_process	translation
ARF1	0003747	molecular_function	translation release factor activity
ARF1	0006415	biological_process	translational termination
L10E	0003735	molecular_function	structural constituent of ribosome
L10E	0005840	cellular_component	ribosome
L10E	0006412	biological_process	translation
L10E	1990904	cellular_component	ribonucleoprotein complex
L13P	0003729	molecular_function	mRNA binding
L13P	0003735	molecular_function	structural constituent of ribosome
L13P	0005840	cellular_component	ribosome
L13P	0006412	biological_process	translation
L13P	0015934	cellular_component	large ribosomal subunit
L13P	0017148	biological_process	negative regulation of translation
L13P	0022625	cellular_component	cytosolic large ribosomal subunit
L13P	1990904	cellular_component	ribonucleoprotein complex
L141	0003723	molecular_function	RNA binding
L141	0003735	molecular_function	structural constituent of ribosome
L141	0005840	cellular_component	ribosome
L141	0006412	biological_process	translation
L141	0022625	cellular_component	cytosolic large ribosomal subunit
L141	0042273	biological_process	ribosomal large subunit biogenesis
L141	1990904	cellular_component	ribonucleoprotein complex
L142	0003723	molecular_function	RNA binding
L142	0003735	molecular_function	structural constituent of ribosome
L142	0005840	cellular_component	ribosome
L142	0006412	biological_process	translation
L142	0022625	cellular_component	cytosolic large ribosomal subunit
L142	0042273	biological_process	ribosomal large subunit biogenesis
L142	1990904	cellular_component	ribonucleoprotein complex
L14P	0003735	molecular_function	structural constituent of ribosome
L14P	0005840	cellular_component	ribosome
L14P	0006412	biological_process	translation
L14P	0019843	molecular_function	rRNA binding
L14P	0022625	cellular_component	cytosolic large ribosomal subunit
L14P	0070180	molecular_function	large ribosomal subunit rRNA binding
L14P	1990904	cellular_component	ribonucleoprotein complex
L15E	0003735	molecular_function	structural constituent of ribosome
L15E	0005840	cellular_component	ribosome
L15E	0006412	biological_process	translation
L15P	0003735	molecular_function	structural constituent of ribosome
L15P	0005840	cellular_component	ribosome
L15P	0006412	biological_process	translation
L15P	0015934	cellular_component	large ribosomal subunit
L15P	0019843	molecular_function	rRNA binding
L15P	0022625	cellular_component	cytosolic large ribosomal subunit
L15P	1990904	cellular_component	ribonucleoprotein complex
L18E	0003735	molecular_function	structural constituent of ribosome
L18E	0005840	cellular_component	ribosome
L18E	0006412	biological_process	translation
L18E	1990904	cellular_component	ribonucleoprotein complex
L18P	0000027	biological_process	ribosomal large subunit assembly
L18P	0003735	molecular_function	structural constituent of ribosome
L18P	0005840	cellular_component	ribosome
L18P	0006412	biological_process	translation
L18P	0008097	molecular_function	5S rRNA binding
L18P	0019843	molecular_function	rRNA binding
L18P	0022625	cellular_component	cytosolic large ribosomal subunit
L18P	1990904	cellular_component	ribonucleoprotein complex
L19E	0003723	molecular_function	RNA binding
L19E	0003735	molecular_function	structural constituent of ribosome
L19E	0005840	cellular_component	ribosome
L19E	0006412	biological_process	translation
L19E	0019843	molecular_function	rRNA binding
L19E	0022625	cellular_component	cytosolic large ribosomal subunit
L19E	0070180	molecular_function	large ribosomal subunit rRNA binding
L19E	1990904	cellular_component	ribonucleoprotein complex
L21E	0003735	molecular_function	structural constituent of ribosome
L21E	0005840	cellular_component	ribosome
L21E	0006412	biological_process	translation
L21E	1990904	cellular_component	ribonucleoprotein complex
L22P	0002181	biological_process	cytoplasmic translation
L22P	0003735	molecular_function	structural constituent of ribosome
L22P	0005840	cellular_component	ribosome
L22P	0006412	biological_process	translation
L22P	0015934	cellular_component	large ribosomal subunit
L22P	0019843	molecular_function	rRNA binding
L22P	0022625	cellular_component	cytosolic large ribosomal subunit
L22P	1990904	cellular_component	ribonucleoprotein complex
L23P	0003735	molecular_function	structural constituent of ribosome
L23P	0005840	cellular_component	ribosome
L23P	0006412	biological_process	translation
L23P	0019843	molecular_function	rRNA binding
L23P	1990904	cellular_component	ribonucleoprotein complex
L24E	0003735	molecular_function	structural constituent of ribosome
L24E	0005840	cellular_component	ribosome
L24E	0006412	biological_process	translation
L24P	0003723	molecular_function	RNA binding
L24P	0003735	molecular_function	structural constituent of ribosome
L24P	0005840	cellular_component	ribosome
L24P	0006412	biological_process	translation
L24P	0015934	cellular_component	large ribosomal subunit
L24P	0019843	molecular_function	rRNA binding
L24P	1990904	cellular_component	ribonucleoprotein complex
L29P	0003735	molecular_function	structural constituent of ribosome
L29P	0005840	cellular_component	ribosome
L29P	0006412	biological_process	translation
L29P	1990904	cellular_component	ribonucleoprotein complex
L30E	0003723	molecular_function	RNA binding
L30E	0003735	molecular_function	structural constituent of ribosome
L30E	0005840	cellular_component	ribosome
L30E	0006412	biological_process	translation
L30E	0022625	cellular_component	cytosolic large ribosomal subunit
L30E	1990904	cellular_component	ribonucleoprotein complex
L30P	0000463	biological_process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
L30P	0003723	molecular_function	RNA binding
L30P	0003735	molecular_function	structural constituent of ribosome
L30P	0005840	cellular_component	ribosome
L30P	0006412	biological_process	translation
L30P	0015934	cellular_component	large ribosomal subunit
L30P	0022625	cellular_component	cytosolic large ribosomal subunit
L30P	1990904	cellular_component	ribonucleoprotein complex
L31E	0003735	molecular_function	structural constituent of ribosome
L31E	0005840	cellular_component	ribosome
L31E	0006412	biological_process	translation
L32E	0003735	molecular_function	structural constituent of ribosome
L32E	0005840	cellular_component	ribosome
L32E	0006412	biological_process	translation
L32E	0022625	cellular_component	cytosolic large ribosomal subunit
L32E	1990904	cellular_component	ribonucleoprotein complex
L34E	0003735	molecular_function	structural constituent of ribosome
L34E	0005840	cellular_component	ribosome
L34E	0006412	biological_process	translation
L37A	0003735	molecular_function	structural constituent of ribosome
L37A	0005840	cellular_component	ribosome
L37A	0006412	biological_process	translation
L37A	0008270	molecular_function	zinc ion binding
L37A	0019843	molecular_function	rRNA binding
L37A	0070180	molecular_function	large ribosomal subunit rRNA binding
L37A	1990904	cellular_component	ribonucleoprotein complex
L37E	0003735	molecular_function	structural constituent of ribosome
L37E	0005840	cellular_component	ribosome
L37E	0006412	biological_process	translation
L39E	0003735	molecular_function	structural constituent of ribosome
L39E	0005840	cellular_component	ribosome
L39E	0006412	biological_process	translation
L39E	0022625	cellular_component	cytosolic large ribosomal subunit
L39E	1990904	cellular_component	ribonucleoprotein complex
L40E	0003735	molecular_function	structural constituent of ribosome
L40E	0005840	cellular_component	ribosome
L40E	0006412	biological_process	translation
L40E	1990904	cellular_component	ribonucleoprotein complex
L44E	0003735	molecular_function	structural constituent of ribosome
L44E	0005840	cellular_component	ribosome
L44E	0006412	biological_process	translation
L44E	0008270	molecular_function	zinc ion binding
L44E	0019843	molecular_function	rRNA binding
L44E	0046872	molecular_function	metal ion binding
L44E	0070180	molecular_function	large ribosomal subunit rRNA binding
L44E	1990904	cellular_component	ribonucleoprotein complex
L7A1	0001682	biological_process	tRNA 5'-leader removal
L7A1	0003723	molecular_function	RNA binding
L7A1	0003735	molecular_function	structural constituent of ribosome
L7A1	0004526	molecular_function	ribonuclease P activity
L7A1	0005737	cellular_component	cytoplasm
L7A1	0005840	cellular_component	ribosome
L7A1	0006412	biological_process	translation
L7A1	0008033	biological_process	tRNA processing
L7A1	0019843	molecular_function	rRNA binding
L7A1	0042254	biological_process	ribosome biogenesis
L7A1	1990904	cellular_component	ribonucleoprotein complex
L7A2	0001682	biological_process	tRNA 5'-leader removal
L7A2	0003723	molecular_function	RNA binding
L7A2	0003735	molecular_function	structural constituent of ribosome
L7A2	0004526	molecular_function	ribonuclease P activity
L7A2	0005737	cellular_component	cytoplasm
L7A2	0005840	cellular_component	ribosome
L7A2	0006412	biological_process	translation
L7A2	0008033	biological_process	tRNA processing
L7A2	0019843	molecular_function	rRNA binding
L7A2	0042254	biological_process	ribosome biogenesis
L7A2	1990904	cellular_component	ribonucleoprotein complex

Functional Information from PROSITE/UniProt

site_id	PS00049
Number of Residues	27
Details	RIBOSOMAL_L14 Ribosomal protein L14 signature. AVIVrqrmpfrrp.DGtwisFedNavVI

Chain	Residue	Details
L14P	ALA77-ILE103

site_id	PS00050
Number of Residues	16
Details	RIBOSOMAL_L23 Ribosomal protein L23 signature. KKAYVKLKqeykasdV

Chain	Residue	Details
L23P	LYS60-VAL75

site_id	PS00051
Number of Residues	17
Details	RIBOSOMAL_L39E Ribosomal protein L39e signature. KTqaeIrfNplrRNWRR

Chain	Residue	Details
L39E	LYS30-ARG46

site_id	PS00358
Number of Residues	17
Details	RIBOSOMAL_L5 Ribosomal protein L5 signature. VqeLTGVkpVyTkGRkS

Chain	Residue	Details
AL5P	VAL40-SER56

site_id	PS00464
Number of Residues	25
Details	RIBOSOMAL_L22 Ribosomal protein L22 signature. KryMtRAfGRstrkykylSHIEViL

Chain	Residue	Details
L22P	LYS129-LEU153

site_id	PS00474
Number of Residues	24
Details	RIBOSOMAL_L3 Ribosomal protein L3 signature. FregqltDiiGvTkGKGfqGvikR

Chain	Residue	Details
AL3P	PHE200-ARG223

site_id	PS00475
Number of Residues	31
Details	RIBOSOMAL_L15 Ribosomal protein L15 signature. KLLGgGnLrlp..LvIkvakATekAkerVkeiG

Chain	Residue	Details
L15P	LYS105-GLY135
L18E	LYS62-GLY92

site_id	PS00526
Number of Residues	20
Details	RIBOSOMAL_L19E Ribosomal protein L19e signature. QRRLaAdiagVGlnnIKFNP

Chain	Residue	Details
L19E	GLN7-PRO26

site_id	PS00579
Number of Residues	15
Details	RIBOSOMAL_L29 Ribosomal protein L29 signature. NTASIKnTRKDIARI

Chain	Residue	Details
L29P	ASN41-ILE55

site_id	PS00580
Number of Residues	23
Details	RIBOSOMAL_L32E Ribosomal protein L32e signature. FlRfdwdKyyRIgrqerWRKprG

Chain	Residue	Details
L32E	PHE18-GLY40

site_id	PS00700
Number of Residues	22
Details	RIBOSOMAL_L6_2 Ribosomal protein L6 signature 2. SstkIvgYdrRiFsDGIYIykK

Chain	Residue	Details
AL6P	SER159-LYS180

site_id	PS00709
Number of Residues	25
Details	RIBOSOMAL_L30E_1 Ribosomal protein L30e signature 1. SgkvilGtRktLKllKtGkvKgVVV

Chain	Residue	Details
L30E	SER15-VAL39

site_id	PS00783
Number of Residues	23
Details	RIBOSOMAL_L13 Ribosomal protein L13 signature. VRGMLPknkl.GKqiyrnLkAYiG

Chain	Residue	Details
L13P	VAL86-GLY108

site_id	PS00993
Number of Residues	21
Details	RIBOSOMAL_L30E_2 Ribosomal protein L30e signature 2. ELGTlcGKpfmvsvIgIvDeG

Chain	Residue	Details
L30E	GLU71-GLY91

site_id	PS01073
Number of Residues	18
Details	RIBOSOMAL_L24E Ribosomal protein L24e signature. FcGkdIlPGtGlmYvRnD

Chain	Residue	Details
L24E	PHE9-ASP26

site_id	PS01077
Number of Residues	21
Details	RIBOSOMAL_L37E Ribosomal protein L37e signature. GTpSfGkMnktptHvrCrRCG

Chain	Residue	Details
L37E	GLY3-GLY23

site_id	PS01082
Number of Residues	18
Details	RIBOSOMAL_L7AE Ribosomal protein L7Ae signature. CeekkIPYvyVpSKksLG

Chain	Residue	Details
L7A1	CYS70-GLY87

site_id	PS01106
Number of Residues	18
Details	RIBOSOMAL_L18E Ribosomal protein L18e signature. EeLeaPRrkRAyINIyKI

Chain	Residue	Details
L18E	GLU30-ILE47

site_id	PS01145
Number of Residues	14
Details	RIBOSOMAL_L34E Ribosomal protein L34e signature. SgSfRkvfvKLPSG

Chain	Residue	Details
L34E	SER8-GLY21

site_id	PS01171
Number of Residues	26
Details	RIBOSOMAL_L21E Ribosomal protein L21e signature. GEyVvvkinpsihk.GmpHrrYhGkVG

Chain	Residue	Details
L21E	GLY39-GLY64

site_id	PS01194
Number of Residues	24
Details	RIBOSOMAL_L15E Ribosomal protein L15e signature. NRARaLGYkAkqGFVMVRvRVrRG

Chain	Residue	Details
L15E	ASN46-GLY69

site_id	PS01199
Number of Residues	20
Details	RIBOSOMAL_L1 Ribosomal protein L1 signature. MalAgriLGpaLGPRGkFPT

Chain	Residue	Details
AL1P	MET120-THR139

site_id	PS01257
Number of Residues	22
Details	RIBOSOMAL_L10E Ribosomal protein L10e signature. ADRlqdGMRlSFGKPiGtaARL

Chain	Residue	Details
L10E	ALA106-LEU127

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	18
Details	ZN_FING: C4-type => ECO:0000255\|HAMAP-Rule:MF_00547

Chain	Residue	Details
L37E	CYS19-CYS37

site_id	SWS_FT_FI2
Number of Residues	4
Details	BINDING: BINDING => ECO:0000255\|HAMAP-Rule:MF_00547

Chain	Residue	Details
L37E	CYS19
L37E	CYS22
L37E	CYS34
L37E	CYS37

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		Validation report (PDF)