8HKQ
ion channel
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006813 | biological_process | potassium ion transport |
| A | 0016020 | cellular_component | membrane |
| B | 0006813 | biological_process | potassium ion transport |
| B | 0016020 | cellular_component | membrane |
| C | 0006813 | biological_process | potassium ion transport |
| C | 0016020 | cellular_component | membrane |
| D | 0006813 | biological_process | potassium ion transport |
| D | 0016020 | cellular_component | membrane |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4032 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000305 |
| Chain | Residue | Details |
| D | MET1-ASN93 | |
| C | SER198-SER211 | |
| C | ILE253-SER265 | |
| C | LEU339-ARG1230 | |
| B | MET1-ASN93 | |
| B | SER198-SER211 | |
| B | ILE253-SER265 | |
| B | LEU339-ARG1230 | |
| D | SER198-SER211 | |
| D | ILE253-SER265 | |
| D | LEU339-ARG1230 | |
| A | MET1-ASN93 | |
| A | SER198-SER211 | |
| A | ILE253-SER265 | |
| A | LEU339-ARG1230 | |
| C | MET1-ASN93 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 128 |
| Details | TRANSMEM: Helical; Name=Segment S1 => ECO:0000269|PubMed:23086396, ECO:0007744|PDB:8HIR |
| Chain | Residue | Details |
| D | LEU113-CYS145 | |
| A | LEU113-CYS145 | |
| C | LEU113-CYS145 | |
| B | LEU113-CYS145 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 156 |
| Details | TOPO_DOM: Extracellular => ECO:0000305 |
| Chain | Residue | Details |
| D | TRP146-ARG172 | |
| C | TRP228-LEU234 | |
| C | ARG294-SER300 | |
| C | PRO322-LYS323 | |
| B | TRP146-ARG172 | |
| B | TRP228-LEU234 | |
| B | ARG294-SER300 | |
| B | PRO322-LYS323 | |
| D | TRP228-LEU234 | |
| D | ARG294-SER300 | |
| D | PRO322-LYS323 | |
| A | TRP146-ARG172 | |
| A | TRP228-LEU234 | |
| A | ARG294-SER300 | |
| A | PRO322-LYS323 | |
| C | TRP146-ARG172 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 96 |
| Details | TRANSMEM: Helical; Name=Segment S2 => ECO:0000269|PubMed:23086396, ECO:0007744|PDB:8HIR |
| Chain | Residue | Details |
| D | LYS173-LEU197 | |
| A | LYS173-LEU197 | |
| C | LYS173-LEU197 | |
| B | LYS173-LEU197 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 60 |
| Details | TRANSMEM: Helical; Name=Segment S3 => ECO:0000269|PubMed:23086396, ECO:0007744|PDB:8HIR |
| Chain | Residue | Details |
| D | PHE212-PHE227 | |
| A | PHE212-PHE227 | |
| C | PHE212-PHE227 | |
| B | PHE212-PHE227 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 68 |
| Details | TRANSMEM: Helical; Name=Segment S4 => ECO:0000269|PubMed:23086396, ECO:0007744|PDB:8HIR |
| Chain | Residue | Details |
| D | PHE235-MET252 | |
| A | PHE235-MET252 | |
| C | PHE235-MET252 | |
| B | PHE235-MET252 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 108 |
| Details | TRANSMEM: Helical; Name=Segment S5 => ECO:0000305 |
| Chain | Residue | Details |
| D | ALA266-GLU293 | |
| A | ALA266-GLU293 | |
| C | ALA266-GLU293 | |
| B | ALA266-GLU293 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 80 |
| Details | INTRAMEM: Pore-forming => ECO:0000269|PubMed:23086396, ECO:0007744|PDB:8HIR |
| Chain | Residue | Details |
| D | LEU301-THR321 | |
| A | LEU301-THR321 | |
| C | LEU301-THR321 | |
| B | LEU301-THR321 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 132 |
| Details | TRANSMEM: Helical; Name=Segment S6 => ECO:0000269|PubMed:23086396, ECO:0007744|PDB:8HIR |
| Chain | Residue | Details |
| D | ILE324-GLN357 | |
| A | ILE324-GLN357 | |
| C | ILE324-GLN357 | |
| B | ILE324-GLN357 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 40 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:37494189, ECO:0007744|PDB:8HIR |
| Chain | Residue | Details |
| D | VAL315 | |
| D | HIS787 | |
| A | VAL315 | |
| A | GLY316 | |
| A | LEU532 | |
| A | HIS535 | |
| A | SER557 | |
| A | ASN559 | |
| A | CYS777 | |
| A | CYS778 | |
| A | CYS785 | |
| D | GLY316 | |
| A | HIS787 | |
| C | VAL315 | |
| C | GLY316 | |
| C | LEU532 | |
| C | HIS535 | |
| C | SER557 | |
| C | ASN559 | |
| C | CYS777 | |
| C | CYS778 | |
| C | CYS785 | |
| D | LEU532 | |
| C | HIS787 | |
| B | VAL315 | |
| B | GLY316 | |
| B | LEU532 | |
| B | HIS535 | |
| B | SER557 | |
| B | ASN559 | |
| B | CYS777 | |
| B | CYS778 | |
| B | CYS785 | |
| D | HIS535 | |
| B | HIS787 | |
| D | SER557 | |
| D | ASN559 | |
| D | CYS777 | |
| D | CYS778 | |
| D | CYS785 |
| site_id | SWS_FT_FI11 |
| Number of Residues | 24 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:37494189, ECO:0007744|PDB:8HKK |
| Chain | Residue | Details |
| D | ARG780 | |
| A | TYR790 | |
| A | TYR796 | |
| A | PHE798 | |
| C | ARG780 | |
| C | LYS783 | |
| C | ASN788 | |
| C | TYR790 | |
| C | TYR796 | |
| C | PHE798 | |
| B | ARG780 | |
| D | LYS783 | |
| B | LYS783 | |
| B | ASN788 | |
| B | TYR790 | |
| B | TYR796 | |
| B | PHE798 | |
| D | ASN788 | |
| D | TYR790 | |
| D | TYR796 | |
| D | PHE798 | |
| A | ARG780 | |
| A | LYS783 | |
| A | ASN788 |
| site_id | SWS_FT_FI12 |
| Number of Residues | 24 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:37494189, ECO:0007744|PDB:8HK6 |
| Chain | Residue | Details |
| D | GLY797 | |
| A | ASP839 | |
| A | GLY861 | |
| A | ASP884 | |
| C | GLY797 | |
| C | SER806 | |
| C | LEU837 | |
| C | ASP839 | |
| C | GLY861 | |
| C | ASP884 | |
| B | GLY797 | |
| D | SER806 | |
| B | SER806 | |
| B | LEU837 | |
| B | ASP839 | |
| B | GLY861 | |
| B | ASP884 | |
| D | LEU837 | |
| D | ASP839 | |
| D | GLY861 | |
| D | ASP884 | |
| A | GLY797 | |
| A | SER806 | |
| A | LEU837 |
| site_id | SWS_FT_FI13 |
| Number of Residues | 8 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| D | ASN152 | |
| D | ASN156 | |
| A | ASN152 | |
| A | ASN156 | |
| C | ASN152 | |
| C | ASN156 | |
| B | ASN152 | |
| B | ASN156 |
