8HF5

Cryo-EM structure of nucleotide-bound ComA at outward-facing state with EC gate open conformation

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0005524	molecular_function	ATP binding
A	0005886	cellular_component	plasma membrane
A	0006508	biological_process	proteolysis
A	0006869	biological_process	lipid transport
A	0008233	molecular_function	peptidase activity
A	0008234	molecular_function	cysteine-type peptidase activity
A	0016020	cellular_component	membrane
A	0016787	molecular_function	hydrolase activity
A	0016887	molecular_function	ATP hydrolysis activity
A	0030420	biological_process	establishment of competence for transformation
A	0034040	molecular_function	ATPase-coupled lipid transmembrane transporter activity
A	0043213	biological_process	bacteriocin transport
A	0043214	molecular_function	ABC-type bacteriocin transporter activity
A	0055085	biological_process	transmembrane transport
A	0140359	molecular_function	ABC-type transporter activity
B	0000166	molecular_function	nucleotide binding
B	0005524	molecular_function	ATP binding
B	0005886	cellular_component	plasma membrane
B	0006508	biological_process	proteolysis
B	0006869	biological_process	lipid transport
B	0008233	molecular_function	peptidase activity
B	0008234	molecular_function	cysteine-type peptidase activity
B	0016020	cellular_component	membrane
B	0016787	molecular_function	hydrolase activity
B	0016887	molecular_function	ATP hydrolysis activity
B	0030420	biological_process	establishment of competence for transformation
B	0034040	molecular_function	ATPase-coupled lipid transmembrane transporter activity
B	0043213	biological_process	bacteriocin transport
B	0043214	molecular_function	ABC-type bacteriocin transporter activity
B	0055085	biological_process	transmembrane transport
B	0140359	molecular_function	ABC-type transporter activity

Functional Information from PROSITE/UniProt

site_id	PS00211
Number of Residues	15
Details	ABC_TRANSPORTER_1 ABC transporters family signature. ISGGQRQRIALARAL

Chain	Residue	Details
A	ILE622-LEU636

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI3
Number of Residues	466
Details	Domain: {"description":"ABC transporter","evidences":[{"source":"PROSITE-ProRule","id":"PRU00362","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU00434","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	240
Details	Transmembrane: {"description":"Helical","evidences":[{"source":"PROSITE-ProRule","id":"PRU00441","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	564
Details	Domain: {"description":"ABC transmembrane type-1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00441","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	14
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00362","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU00434","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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