8HDK
Structure of the Rat GluN1-GluN2C NMDA receptor in complex with glycine and glutamate (minor class in symmetry)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005216 | molecular_function | monoatomic ion channel activity |
| A | 0006811 | biological_process | monoatomic ion transport |
| A | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| A | 0016020 | cellular_component | membrane |
| A | 0038023 | molecular_function | signaling receptor activity |
| B | 0005216 | molecular_function | monoatomic ion channel activity |
| B | 0006811 | biological_process | monoatomic ion transport |
| B | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| B | 0016020 | cellular_component | membrane |
| B | 0038023 | molecular_function | signaling receptor activity |
| C | 0005216 | molecular_function | monoatomic ion channel activity |
| C | 0006811 | biological_process | monoatomic ion transport |
| C | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| C | 0016020 | cellular_component | membrane |
| C | 0038023 | molecular_function | signaling receptor activity |
| D | 0005216 | molecular_function | monoatomic ion channel activity |
| D | 0006811 | biological_process | monoatomic ion transport |
| D | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
| D | 0016020 | cellular_component | membrane |
| D | 0038023 | molecular_function | signaling receptor activity |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1068 |
| Details | TOPO_DOM: Extracellular => ECO:0000250|UniProtKB:Q00960 |
| Chain | Residue | Details |
| B | ARG20-ALA554 | |
| D | ARG20-ALA554 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 66 |
| Details | TRANSMEM: Helical => ECO:0000250|UniProtKB:Q00960 |
| Chain | Residue | Details |
| B | VAL555-MET573 | |
| B | MET628-TYR643 | |
| D | VAL555-MET573 | |
| D | MET628-TYR643 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 64 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000250|UniProtKB:Q00960 |
| Chain | Residue | Details |
| B | PHE574-GLY600 | |
| B | ARG621-ILE627 | |
| D | PHE574-GLY600 | |
| D | ARG621-ILE627 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 38 |
| Details | INTRAMEM: Discontinuously helical => ECO:0000250|UniProtKB:Q00960 |
| Chain | Residue | Details |
| B | LYS601-PRO620 | |
| D | LYS601-PRO620 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 6 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:Q00959 |
| Chain | Residue | Details |
| B | SER509 | |
| B | ARG516 | |
| B | SER687 | |
| D | SER509 | |
| D | ARG516 | |
| D | SER687 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:Q00960 |
| Chain | Residue | Details |
| B | THR511 | |
| B | ASP729 | |
| D | THR511 | |
| D | ASP729 | |
| C | SER688 | |
| C | ASP732 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | SITE: Functional determinant of NMDA receptors => ECO:0000250 |
| Chain | Residue | Details |
| B | ASN612 | |
| D | ASN612 | |
| C | ASN61 | |
| C | ASN239 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 12 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| B | ASN70 | |
| D | ASN438 | |
| D | ASN539 | |
| D | ASN685 | |
| B | ASN73 | |
| B | ASN337 | |
| B | ASN438 | |
| B | ASN539 | |
| B | ASN685 | |
| D | ASN70 | |
| D | ASN73 | |
| D | ASN337 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:24876489, ECO:0007744|PDB:3Q41, ECO:0007744|PDB:4PE5 |
| Chain | Residue | Details |
| A | ASN276 | |
| C | ASN276 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:24876489, ECO:0007744|PDB:4PE5 |
| Chain | Residue | Details |
| A | ASN300 | |
| C | ASN300 |
| site_id | SWS_FT_FI11 |
| Number of Residues | 4 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0007744|PubMed:24090084 |
| Chain | Residue | Details |
| A | ASN350 | |
| A | ASN771 | |
| C | ASN350 | |
| C | ASN771 |
| site_id | SWS_FT_FI12 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:24876489, ECO:0007744|PDB:4PE5, ECO:0007744|PubMed:24090084 |
| Chain | Residue | Details |
| A | ASN440 | |
| C | ASN440 |
| site_id | SWS_FT_FI13 |
| Number of Residues | 6 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN471 | |
| A | ASN491 | |
| A | ASN674 | |
| C | ASN471 | |
| C | ASN491 | |
| C | ASN674 |
