Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

8H9J

Human ATP synthase state2 subregion 3

Functional Information from GO Data

Chain	GOid	namespace	contents
1	0015078	molecular_function	proton transmembrane transporter activity
1	0015986	biological_process	proton motive force-driven ATP synthesis
1	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
1	0045263	cellular_component	proton-transporting ATP synthase complex, coupling factor F(o)
1	1902600	biological_process	proton transmembrane transport
2	0015078	molecular_function	proton transmembrane transporter activity
2	0015986	biological_process	proton motive force-driven ATP synthesis
2	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
2	0045263	cellular_component	proton-transporting ATP synthase complex, coupling factor F(o)
2	1902600	biological_process	proton transmembrane transport
3	0015078	molecular_function	proton transmembrane transporter activity
3	0015986	biological_process	proton motive force-driven ATP synthesis
3	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
3	0045263	cellular_component	proton-transporting ATP synthase complex, coupling factor F(o)
3	1902600	biological_process	proton transmembrane transport
4	0015078	molecular_function	proton transmembrane transporter activity
4	0015986	biological_process	proton motive force-driven ATP synthesis
4	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
4	0045263	cellular_component	proton-transporting ATP synthase complex, coupling factor F(o)
4	1902600	biological_process	proton transmembrane transport
5	0015078	molecular_function	proton transmembrane transporter activity
5	0015986	biological_process	proton motive force-driven ATP synthesis
5	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
5	0045263	cellular_component	proton-transporting ATP synthase complex, coupling factor F(o)
5	1902600	biological_process	proton transmembrane transport
6	0015078	molecular_function	proton transmembrane transporter activity
6	0015986	biological_process	proton motive force-driven ATP synthesis
6	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
6	0045263	cellular_component	proton-transporting ATP synthase complex, coupling factor F(o)
6	1902600	biological_process	proton transmembrane transport
7	0015078	molecular_function	proton transmembrane transporter activity
7	0015986	biological_process	proton motive force-driven ATP synthesis
7	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
7	0045263	cellular_component	proton-transporting ATP synthase complex, coupling factor F(o)
7	1902600	biological_process	proton transmembrane transport
8	0015078	molecular_function	proton transmembrane transporter activity
8	0015986	biological_process	proton motive force-driven ATP synthesis
8	0033177	cellular_component	proton-transporting two-sector ATPase complex, proton-transporting domain
8	0045263	cellular_component	proton-transporting ATP synthase complex, coupling factor F(o)
8	1902600	biological_process	proton transmembrane transport
G	0000275	cellular_component	mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)
G	0003723	molecular_function	RNA binding
G	0005515	molecular_function	protein binding
G	0005739	cellular_component	mitochondrion
G	0005743	cellular_component	mitochondrial inner membrane
G	0005753	cellular_component	mitochondrial proton-transporting ATP synthase complex
G	0005759	cellular_component	mitochondrial matrix
G	0006119	biological_process	oxidative phosphorylation
G	0006754	biological_process	ATP biosynthetic process
G	0015986	biological_process	proton motive force-driven ATP synthesis
G	0016020	cellular_component	membrane
G	0016887	molecular_function	ATP hydrolysis activity
G	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
G	0045261	cellular_component	proton-transporting ATP synthase complex, catalytic core F(1)
G	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
G	1902600	biological_process	proton transmembrane transport
H	0015986	biological_process	proton motive force-driven ATP synthesis
H	0045261	cellular_component	proton-transporting ATP synthase complex, catalytic core F(1)
H	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
I	0000275	cellular_component	mitochondrial proton-transporting ATP synthase complex, catalytic sector F(1)
I	0005515	molecular_function	protein binding
I	0005739	cellular_component	mitochondrion
I	0005743	cellular_component	mitochondrial inner membrane
I	0005753	cellular_component	mitochondrial proton-transporting ATP synthase complex
I	0005759	cellular_component	mitochondrial matrix
I	0006754	biological_process	ATP biosynthetic process
I	0015986	biological_process	proton motive force-driven ATP synthesis
I	0016787	molecular_function	hydrolase activity
I	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
I	0045261	cellular_component	proton-transporting ATP synthase complex, catalytic core F(1)
I	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
I	1902600	biological_process	proton transmembrane transport
K	0000276	cellular_component	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
K	0015078	molecular_function	proton transmembrane transporter activity
K	0015986	biological_process	proton motive force-driven ATP synthesis
M	0000274	cellular_component	mitochondrial proton-transporting ATP synthase, stator stalk
M	0000276	cellular_component	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
M	0005515	molecular_function	protein binding
M	0005739	cellular_component	mitochondrion
M	0005743	cellular_component	mitochondrial inner membrane
M	0005753	cellular_component	mitochondrial proton-transporting ATP synthase complex
M	0015078	molecular_function	proton transmembrane transporter activity
M	0015986	biological_process	proton motive force-driven ATP synthesis
M	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
M	0045263	cellular_component	proton-transporting ATP synthase complex, coupling factor F(o)
M	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
M	1902600	biological_process	proton transmembrane transport
N	0005515	molecular_function	protein binding
N	0005739	cellular_component	mitochondrion
N	0005743	cellular_component	mitochondrial inner membrane
N	0005753	cellular_component	mitochondrial proton-transporting ATP synthase complex
N	0006754	biological_process	ATP biosynthetic process
N	0015078	molecular_function	proton transmembrane transporter activity
N	0015986	biological_process	proton motive force-driven ATP synthesis
N	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
N	0045263	cellular_component	proton-transporting ATP synthase complex, coupling factor F(o)
N	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
N	0055093	biological_process	response to hyperoxia
N	1902600	biological_process	proton transmembrane transport
P	0003674	molecular_function	molecular_function
P	0005575	cellular_component	cellular_component
P	0005739	cellular_component	mitochondrion
P	0005743	cellular_component	mitochondrial inner membrane
P	0005753	cellular_component	mitochondrial proton-transporting ATP synthase complex
P	0008150	biological_process	biological_process
P	0015986	biological_process	proton motive force-driven ATP synthesis
P	0016020	cellular_component	membrane
P	0031966	cellular_component	mitochondrial membrane
Q	0000276	cellular_component	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
Q	0005515	molecular_function	protein binding
Q	0005739	cellular_component	mitochondrion
Q	0005743	cellular_component	mitochondrial inner membrane
Q	0005753	cellular_component	mitochondrial proton-transporting ATP synthase complex
Q	0006754	biological_process	ATP biosynthetic process
Q	0015078	molecular_function	proton transmembrane transporter activity
Q	0015986	biological_process	proton motive force-driven ATP synthesis
Q	0016020	cellular_component	membrane
Q	0031966	cellular_component	mitochondrial membrane
Q	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
Q	0045263	cellular_component	proton-transporting ATP synthase complex, coupling factor F(o)
Q	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
Q	1902600	biological_process	proton transmembrane transport
R	0005739	cellular_component	mitochondrion
R	0005743	cellular_component	mitochondrial inner membrane
R	0005753	cellular_component	mitochondrial proton-transporting ATP synthase complex
R	0006754	biological_process	ATP biosynthetic process
R	0015986	biological_process	proton motive force-driven ATP synthesis
R	0031965	cellular_component	nuclear membrane
R	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
R	0045263	cellular_component	proton-transporting ATP synthase complex, coupling factor F(o)
R	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
R	1902600	biological_process	proton transmembrane transport
S	0000276	cellular_component	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
S	0005515	molecular_function	protein binding
S	0005739	cellular_component	mitochondrion
S	0005743	cellular_component	mitochondrial inner membrane
S	0005753	cellular_component	mitochondrial proton-transporting ATP synthase complex
S	0006754	biological_process	ATP biosynthetic process
S	0015078	molecular_function	proton transmembrane transporter activity
S	0015986	biological_process	proton motive force-driven ATP synthesis
S	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
S	0045263	cellular_component	proton-transporting ATP synthase complex, coupling factor F(o)
S	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
S	1902600	biological_process	proton transmembrane transport
T	0000276	cellular_component	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
T	0005515	molecular_function	protein binding
T	0005739	cellular_component	mitochondrion
T	0005743	cellular_component	mitochondrial inner membrane
T	0005753	cellular_component	mitochondrial proton-transporting ATP synthase complex
T	0006754	biological_process	ATP biosynthetic process
T	0015078	molecular_function	proton transmembrane transporter activity
T	0015986	biological_process	proton motive force-driven ATP synthesis
T	0042776	biological_process	proton motive force-driven mitochondrial ATP synthesis
T	0045263	cellular_component	proton-transporting ATP synthase complex, coupling factor F(o)
T	0046933	molecular_function	proton-transporting ATP synthase activity, rotational mechanism
T	1902600	biological_process	proton transmembrane transport

Functional Information from PROSITE/UniProt

site_id	PS00153
Number of Residues	14
Details	ATPASE_GAMMA ATP synthase gamma subunit signature. ITkEliEiisGAaA

Chain	Residue	Details
G	ILE258-ALA271

site_id	PS00449
Number of Residues	10
Details	ATPASE_A ATP synthase a subunit signature. ALAVRLTANI

Chain	Residue	Details
N	ALA155-ILE164

site_id	PS00605
Number of Residues	22
Details	ATPASE_C ATP synthase c subunit signature. ARNPslkqqLfSyaILgfaLsE

Chain	Residue	Details
6	ALA37-GLU58

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	19
Details	TRANSMEM: Helical => ECO:0000255

Chain	Residue	Details
R	ILE62-TYR81
2	ILE51-ILE71
3	VAL16-TYR36
3	ILE51-ILE71
4	VAL16-TYR36
4	ILE51-ILE71
5	VAL16-TYR36
5	ILE51-ILE71
N	TRP68-LEU88
N	GLN97-PHE117
N	ILE138-VAL158
N	ILE164-ILE184
N	THR189-ILE209
1	VAL16-TYR36
1	ILE51-ILE71
2	VAL16-TYR36

site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: N-acetylalanine => ECO:0007744\|PubMed:19413330, ECO:0007744\|PubMed:22223895, ECO:0007744\|PubMed:25944712

Chain	Residue	Details
R	ALA1
M	LYS62
M	LYS71
K	LYS202
2	GLU58
3	GLU58
4	GLU58
5	GLU58

site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0000250\|UniProtKB:D3ZAF6

Chain	Residue	Details
R	SER2
M	LYS84
M	LYS94
M	LYS143
M	LYS148
3	LYS43
4	LYS43
5	LYS43

site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: N6-acetyllysine => ECO:0000250\|UniProtKB:P56135

Chain	Residue	Details
R	LYS21
G	LYS129

site_id	SWS_FT_FI5
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:23186163

Chain	Residue	Details
G	SER121

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)