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8H6J

Cryo-EM structure of human exon-defined spliceosome in the mature pre-B state.

This is a non-PDB format compatible entry.
Functional Information from GO Data
ChainGOidnamespacecontents
2B0000398biological_processmRNA splicing, via spliceosome
2B0003723molecular_functionRNA binding
2B0005515molecular_functionprotein binding
2B0005634cellular_componentnucleus
2B0005654cellular_componentnucleoplasm
2B0005681cellular_componentspliceosomal complex
2B0005684cellular_componentU2-type spliceosomal complex
2B0005686cellular_componentU2 snRNP
2B0006397biological_processmRNA processing
2B0007283biological_processspermatogenesis
2B0008380biological_processRNA splicing
2B0016604cellular_componentnuclear body
2B0016607cellular_componentnuclear speck
2B0030532cellular_componentsmall nuclear ribonucleoprotein complex
2B0030620molecular_functionU2 snRNA binding
2B0071005cellular_componentU2-type precatalytic spliceosome
2B0071007cellular_componentU2-type catalytic step 2 spliceosome
2B0071013cellular_componentcatalytic step 2 spliceosome
2B1903241biological_processU2-type prespliceosome assembly
2C0000398biological_processmRNA splicing, via spliceosome
2C0001650cellular_componentfibrillar center
2C0003676molecular_functionnucleic acid binding
2C0003723molecular_functionRNA binding
2C0005515molecular_functionprotein binding
2C0005634cellular_componentnucleus
2C0005654cellular_componentnucleoplasm
2C0005681cellular_componentspliceosomal complex
2C0005684cellular_componentU2-type spliceosomal complex
2C0005685cellular_componentU1 snRNP
2C0005686cellular_componentU2 snRNP
2C0006397biological_processmRNA processing
2C0008380biological_processRNA splicing
2C0016607cellular_componentnuclear speck
2C0030619molecular_functionU1 snRNA binding
2C0036464cellular_componentcytoplasmic ribonucleoprotein granule
2C0071005cellular_componentU2-type precatalytic spliceosome
2C0071007cellular_componentU2-type catalytic step 2 spliceosome
2C0071013cellular_componentcatalytic step 2 spliceosome
2C1903241biological_processU2-type prespliceosome assembly
2D0000389biological_processmRNA 3'-splice site recognition
2D0000398biological_processmRNA splicing, via spliceosome
2D0003723molecular_functionRNA binding
2D0005515molecular_functionprotein binding
2D0005634cellular_componentnucleus
2D0005654cellular_componentnucleoplasm
2D0005681cellular_componentspliceosomal complex
2D0005684cellular_componentU2-type spliceosomal complex
2D0005686cellular_componentU2 snRNP
2D0006396biological_processRNA processing
2D0006397biological_processmRNA processing
2D0008380biological_processRNA splicing
2D0016607cellular_componentnuclear speck
2D0045292biological_processmRNA cis splicing, via spliceosome
2D0071004cellular_componentU2-type prespliceosome
2D0071005cellular_componentU2-type precatalytic spliceosome
2D0071013cellular_componentcatalytic step 2 spliceosome
2D1903241biological_processU2-type prespliceosome assembly
2E0000245biological_processspliceosomal complex assembly
2E0000389biological_processmRNA 3'-splice site recognition
2E0000398biological_processmRNA splicing, via spliceosome
2E0003676molecular_functionnucleic acid binding
2E0003723molecular_functionRNA binding
2E0005515molecular_functionprotein binding
2E0005634cellular_componentnucleus
2E0005654cellular_componentnucleoplasm
2E0005681cellular_componentspliceosomal complex
2E0005684cellular_componentU2-type spliceosomal complex
2E0005686cellular_componentU2 snRNP
2E0006397biological_processmRNA processing
2E0008270molecular_functionzinc ion binding
2E0008380biological_processRNA splicing
2E0010976biological_processpositive regulation of neuron projection development
2E0016607cellular_componentnuclear speck
2E0046872molecular_functionmetal ion binding
2E0071004cellular_componentU2-type prespliceosome
2E0071005cellular_componentU2-type precatalytic spliceosome
2E0071013cellular_componentcatalytic step 2 spliceosome
2E1903241biological_processU2-type prespliceosome assembly
2F0000375biological_processRNA splicing, via transesterification reactions
2F0000389biological_processmRNA 3'-splice site recognition
2F0000398biological_processmRNA splicing, via spliceosome
2F0003676molecular_functionnucleic acid binding
2F0003723molecular_functionRNA binding
2F0005515molecular_functionprotein binding
2F0005634cellular_componentnucleus
2F0005654cellular_componentnucleoplasm
2F0005681cellular_componentspliceosomal complex
2F0005684cellular_componentU2-type spliceosomal complex
2F0005686cellular_componentU2 snRNP
2F0006397biological_processmRNA processing
2F0008270molecular_functionzinc ion binding
2F0008380biological_processRNA splicing
2F0016607cellular_componentnuclear speck
2F0046872molecular_functionmetal ion binding
2F0071005cellular_componentU2-type precatalytic spliceosome
2F0071013cellular_componentcatalytic step 2 spliceosome
2F1903241biological_processU2-type prespliceosome assembly
2G0000245biological_processspliceosomal complex assembly
2G0000375biological_processRNA splicing, via transesterification reactions
2G0000398biological_processmRNA splicing, via spliceosome
2G0003723molecular_functionRNA binding
2G0003729molecular_functionmRNA binding
2G0005515molecular_functionprotein binding
2G0005634cellular_componentnucleus
2G0005654cellular_componentnucleoplasm
2G0005681cellular_componentspliceosomal complex
2G0005684cellular_componentU2-type spliceosomal complex
2G0005686cellular_componentU2 snRNP
2G0005689cellular_componentU12-type spliceosomal complex
2G0005730cellular_componentnucleolus
2G0006338biological_processchromatin remodeling
2G0006397biological_processmRNA processing
2G0008380biological_processRNA splicing
2G0016607cellular_componentnuclear speck
2G0034693cellular_componentU11/U12 snRNP
2G0045943biological_processpositive regulation of transcription by RNA polymerase I
2G0045944biological_processpositive regulation of transcription by RNA polymerase II
2G0045945biological_processpositive regulation of transcription by RNA polymerase III
2G0071004cellular_componentU2-type prespliceosome
2G0071005cellular_componentU2-type precatalytic spliceosome
2G0071013cellular_componentcatalytic step 2 spliceosome
2G0110016cellular_componentB-WICH complex
2G1903241biological_processU2-type prespliceosome assembly
2G1990935molecular_functionsplicing factor binding
2H0000398biological_processmRNA splicing, via spliceosome
2H0003723molecular_functionRNA binding
2H0005515molecular_functionprotein binding
2H0005634cellular_componentnucleus
2H0005654cellular_componentnucleoplasm
2H0005681cellular_componentspliceosomal complex
2H0005684cellular_componentU2-type spliceosomal complex
2H0005686cellular_componentU2 snRNP
2H0005689cellular_componentU12-type spliceosomal complex
2H0006397biological_processmRNA processing
2H0008380biological_processRNA splicing
2H0016607cellular_componentnuclear speck
2H0071005cellular_componentU2-type precatalytic spliceosome
2H0071011cellular_componentprecatalytic spliceosome
2H0071013cellular_componentcatalytic step 2 spliceosome
2H1903241biological_processU2-type prespliceosome assembly
2I0000124cellular_componentSAGA complex
2I0000375biological_processRNA splicing, via transesterification reactions
2I0000398biological_processmRNA splicing, via spliceosome
2I0003676molecular_functionnucleic acid binding
2I0005515molecular_functionprotein binding
2I0005634cellular_componentnucleus
2I0005654cellular_componentnucleoplasm
2I0005681cellular_componentspliceosomal complex
2I0005684cellular_componentU2-type spliceosomal complex
2I0005686cellular_componentU2 snRNP
2I0005689cellular_componentU12-type spliceosomal complex
2I0005730cellular_componentnucleolus
2I0006282biological_processregulation of DNA repair
2I0006397biological_processmRNA processing
2I0008380biological_processRNA splicing
2I0030620molecular_functionU2 snRNA binding
2I0042177biological_processnegative regulation of protein catabolic process
2I0043484biological_processregulation of RNA splicing
2I0044877molecular_functionprotein-containing complex binding
2I0045893biological_processpositive regulation of DNA-templated transcription
2I0071005cellular_componentU2-type precatalytic spliceosome
2I0071013cellular_componentcatalytic step 2 spliceosome
2I1903241biological_processU2-type prespliceosome assembly
2J0000375biological_processRNA splicing, via transesterification reactions
2J0000398biological_processmRNA splicing, via spliceosome
2J0003676molecular_functionnucleic acid binding
2J0003723molecular_functionRNA binding
2J0005515molecular_functionprotein binding
2J0005634cellular_componentnucleus
2J0005654cellular_componentnucleoplasm
2J0005681cellular_componentspliceosomal complex
2J0005684cellular_componentU2-type spliceosomal complex
2J0005686cellular_componentU2 snRNP
2J0005689cellular_componentU12-type spliceosomal complex
2J0006397biological_processmRNA processing
2J0008380biological_processRNA splicing
2J0048026biological_processpositive regulation of mRNA splicing, via spliceosome
2J0071005cellular_componentU2-type precatalytic spliceosome
2J1903241biological_processU2-type prespliceosome assembly
2J1990935molecular_functionsplicing factor binding
2K0000398biological_processmRNA splicing, via spliceosome
2K0001825biological_processblastocyst formation
2K0003676molecular_functionnucleic acid binding
2K0003723molecular_functionRNA binding
2K0003729molecular_functionmRNA binding
2K0005515molecular_functionprotein binding
2K0005634cellular_componentnucleus
2K0005654cellular_componentnucleoplasm
2K0005681cellular_componentspliceosomal complex
2K0005684cellular_componentU2-type spliceosomal complex
2K0005686cellular_componentU2 snRNP
2K0005689cellular_componentU12-type spliceosomal complex
2K0006397biological_processmRNA processing
2K0008380biological_processRNA splicing
2K0071011cellular_componentprecatalytic spliceosome
2K0071013cellular_componentcatalytic step 2 spliceosome
2K1903241biological_processU2-type prespliceosome assembly
2L0000398biological_processmRNA splicing, via spliceosome
2L0003677molecular_functionDNA binding
2L0003723molecular_functionRNA binding
2L0005515molecular_functionprotein binding
2L0005634cellular_componentnucleus
2L0005654cellular_componentnucleoplasm
2L0005681cellular_componentspliceosomal complex
2L0005684cellular_componentU2-type spliceosomal complex
2L0005686cellular_componentU2 snRNP
2L0005689cellular_componentU12-type spliceosomal complex
2L0006397biological_processmRNA processing
2L0008270molecular_functionzinc ion binding
2L0008380biological_processRNA splicing
2L0016363cellular_componentnuclear matrix
2L0016607cellular_componentnuclear speck
2L0045893biological_processpositive regulation of DNA-templated transcription
2L0046872molecular_functionmetal ion binding
2L0048863biological_processstem cell differentiation
2L0071005cellular_componentU2-type precatalytic spliceosome
2L0071011cellular_componentprecatalytic spliceosome
2L1903241biological_processU2-type prespliceosome assembly
2M0000124cellular_componentSAGA complex
2M0000398biological_processmRNA splicing, via spliceosome
2M0003723molecular_functionRNA binding
2M0005515molecular_functionprotein binding
2M0005634cellular_componentnucleus
2M0005654cellular_componentnucleoplasm
2M0005681cellular_componentspliceosomal complex
2M0005684cellular_componentU2-type spliceosomal complex
2M0005686cellular_componentU2 snRNP
2M0005689cellular_componentU12-type spliceosomal complex
2M0006282biological_processregulation of DNA repair
2M0006397biological_processmRNA processing
2M0008380biological_processRNA splicing
2M0043484biological_processregulation of RNA splicing
2M0045893biological_processpositive regulation of DNA-templated transcription
2M0071005cellular_componentU2-type precatalytic spliceosome
2M0071011cellular_componentprecatalytic spliceosome
2M1903241biological_processU2-type prespliceosome assembly
2M1990935molecular_functionsplicing factor binding
2a0000387biological_processspliceosomal snRNP assembly
2a0000398biological_processmRNA splicing, via spliceosome
2a0003723molecular_functionRNA binding
2a0005515molecular_functionprotein binding
2a0005634cellular_componentnucleus
2a0005654cellular_componentnucleoplasm
2a0005681cellular_componentspliceosomal complex
2a0005682cellular_componentU5 snRNP
2a0005683cellular_componentU7 snRNP
2a0005684cellular_componentU2-type spliceosomal complex
2a0005685cellular_componentU1 snRNP
2a0005686cellular_componentU2 snRNP
2a0005687cellular_componentU4 snRNP
2a0005689cellular_componentU12-type spliceosomal complex
2a0005697cellular_componenttelomerase holoenzyme complex
2a0005737cellular_componentcytoplasm
2a0005829cellular_componentcytosol
2a0006397biological_processmRNA processing
2a0006479biological_processprotein methylation
2a0008380biological_processRNA splicing
2a0030532cellular_componentsmall nuclear ribonucleoprotein complex
2a0034709cellular_componentmethylosome
2a0034719cellular_componentSMN-Sm protein complex
2a0036261biological_process7-methylguanosine cap hypermethylation
2a0046540cellular_componentU4/U6 x U5 tri-snRNP complex
2a0070034molecular_functiontelomerase RNA binding
2a0070990molecular_functionsnRNP binding
2a0071004cellular_componentU2-type prespliceosome
2a0071005cellular_componentU2-type precatalytic spliceosome
2a0071007cellular_componentU2-type catalytic step 2 spliceosome
2a0071013cellular_componentcatalytic step 2 spliceosome
2a0071204cellular_componenthistone pre-mRNA 3'end processing complex
2a0071208molecular_functionhistone pre-mRNA DCP binding
2a1903241biological_processU2-type prespliceosome assembly
2a1990446molecular_functionU1 snRNP binding
2a1990447molecular_functionU2 snRNP binding
2b0000243cellular_componentcommitment complex
2b0000245biological_processspliceosomal complex assembly
2b0000387biological_processspliceosomal snRNP assembly
2b0000398biological_processmRNA splicing, via spliceosome
2b0003723molecular_functionRNA binding
2b0005515molecular_functionprotein binding
2b0005634cellular_componentnucleus
2b0005654cellular_componentnucleoplasm
2b0005681cellular_componentspliceosomal complex
2b0005682cellular_componentU5 snRNP
2b0005684cellular_componentU2-type spliceosomal complex
2b0005685cellular_componentU1 snRNP
2b0005686cellular_componentU2 snRNP
2b0005687cellular_componentU4 snRNP
2b0005689cellular_componentU12-type spliceosomal complex
2b0005737cellular_componentcytoplasm
2b0005829cellular_componentcytosol
2b0006396biological_processRNA processing
2b0006397biological_processmRNA processing
2b0008380biological_processRNA splicing
2b0030532cellular_componentsmall nuclear ribonucleoprotein complex
2b0034709cellular_componentmethylosome
2b0034715cellular_componentpICln-Sm protein complex
2b0034719cellular_componentSMN-Sm protein complex
2b0036261biological_process7-methylguanosine cap hypermethylation
2b0046540cellular_componentU4/U6 x U5 tri-snRNP complex
2b0071005cellular_componentU2-type precatalytic spliceosome
2b0071007cellular_componentU2-type catalytic step 2 spliceosome
2b0071011cellular_componentprecatalytic spliceosome
2b0071013cellular_componentcatalytic step 2 spliceosome
2b0097526cellular_componentspliceosomal tri-snRNP complex
2b1903241biological_processU2-type prespliceosome assembly
2c0000245biological_processspliceosomal complex assembly
2c0000387biological_processspliceosomal snRNP assembly
2c0000398biological_processmRNA splicing, via spliceosome
2c0003723molecular_functionRNA binding
2c0005515molecular_functionprotein binding
2c0005634cellular_componentnucleus
2c0005654cellular_componentnucleoplasm
2c0005681cellular_componentspliceosomal complex
2c0005682cellular_componentU5 snRNP
2c0005684cellular_componentU2-type spliceosomal complex
2c0005685cellular_componentU1 snRNP
2c0005686cellular_componentU2 snRNP
2c0005687cellular_componentU4 snRNP
2c0005689cellular_componentU12-type spliceosomal complex
2c0005737cellular_componentcytoplasm
2c0005829cellular_componentcytosol
2c0006397biological_processmRNA processing
2c0008380biological_processRNA splicing
2c0030532cellular_componentsmall nuclear ribonucleoprotein complex
2c0034709cellular_componentmethylosome
2c0034715cellular_componentpICln-Sm protein complex
2c0034719cellular_componentSMN-Sm protein complex
2c0036261biological_process7-methylguanosine cap hypermethylation
2c0046540cellular_componentU4/U6 x U5 tri-snRNP complex
2c0070062cellular_componentextracellular exosome
2c0071005cellular_componentU2-type precatalytic spliceosome
2c0071007cellular_componentU2-type catalytic step 2 spliceosome
2c0071011cellular_componentprecatalytic spliceosome
2c0071013cellular_componentcatalytic step 2 spliceosome
2c1903241biological_processU2-type prespliceosome assembly
2d0000387biological_processspliceosomal snRNP assembly
2d0000398biological_processmRNA splicing, via spliceosome
2d0003723molecular_functionRNA binding
2d0005515molecular_functionprotein binding
2d0005634cellular_componentnucleus
2d0005654cellular_componentnucleoplasm
2d0005681cellular_componentspliceosomal complex
2d0005682cellular_componentU5 snRNP
2d0005683cellular_componentU7 snRNP
2d0005684cellular_componentU2-type spliceosomal complex
2d0005685cellular_componentU1 snRNP
2d0005686cellular_componentU2 snRNP
2d0005687cellular_componentU4 snRNP
2d0005689cellular_componentU12-type spliceosomal complex
2d0005737cellular_componentcytoplasm
2d0005829cellular_componentcytosol
2d0006397biological_processmRNA processing
2d0008380biological_processRNA splicing
2d0030532cellular_componentsmall nuclear ribonucleoprotein complex
2d0034709cellular_componentmethylosome
2d0034715cellular_componentpICln-Sm protein complex
2d0034719cellular_componentSMN-Sm protein complex
2d0036261biological_process7-methylguanosine cap hypermethylation
2d0046540cellular_componentU4/U6 x U5 tri-snRNP complex
2d0071005cellular_componentU2-type precatalytic spliceosome
2d0071007cellular_componentU2-type catalytic step 2 spliceosome
2d0071013cellular_componentcatalytic step 2 spliceosome
2d0120114cellular_componentSm-like protein family complex
2d1903241biological_processU2-type prespliceosome assembly
2e0000245biological_processspliceosomal complex assembly
2e0000387biological_processspliceosomal snRNP assembly
2e0000398biological_processmRNA splicing, via spliceosome
2e0003723molecular_functionRNA binding
2e0005515molecular_functionprotein binding
2e0005634cellular_componentnucleus
2e0005654cellular_componentnucleoplasm
2e0005681cellular_componentspliceosomal complex
2e0005682cellular_componentU5 snRNP
2e0005683cellular_componentU7 snRNP
2e0005684cellular_componentU2-type spliceosomal complex
2e0005685cellular_componentU1 snRNP
2e0005686cellular_componentU2 snRNP
2e0005687cellular_componentU4 snRNP
2e0005689cellular_componentU12-type spliceosomal complex
2e0005697cellular_componenttelomerase holoenzyme complex
2e0005737cellular_componentcytoplasm
2e0005829cellular_componentcytosol
2e0006397biological_processmRNA processing
2e0008380biological_processRNA splicing
2e0030532cellular_componentsmall nuclear ribonucleoprotein complex
2e0034709cellular_componentmethylosome
2e0034715cellular_componentpICln-Sm protein complex
2e0034719cellular_componentSMN-Sm protein complex
2e0036261biological_process7-methylguanosine cap hypermethylation
2e0046540cellular_componentU4/U6 x U5 tri-snRNP complex
2e0071005cellular_componentU2-type precatalytic spliceosome
2e0071007cellular_componentU2-type catalytic step 2 spliceosome
2e0071011cellular_componentprecatalytic spliceosome
2e0071013cellular_componentcatalytic step 2 spliceosome
2e1903241biological_processU2-type prespliceosome assembly
2f0000245biological_processspliceosomal complex assembly
2f0000387biological_processspliceosomal snRNP assembly
2f0000398biological_processmRNA splicing, via spliceosome
2f0003723molecular_functionRNA binding
2f0005515molecular_functionprotein binding
2f0005634cellular_componentnucleus
2f0005654cellular_componentnucleoplasm
2f0005681cellular_componentspliceosomal complex
2f0005682cellular_componentU5 snRNP
2f0005683cellular_componentU7 snRNP
2f0005684cellular_componentU2-type spliceosomal complex
2f0005685cellular_componentU1 snRNP
2f0005686cellular_componentU2 snRNP
2f0005687cellular_componentU4 snRNP
2f0005689cellular_componentU12-type spliceosomal complex
2f0005737cellular_componentcytoplasm
2f0005829cellular_componentcytosol
2f0006397biological_processmRNA processing
2f0008380biological_processRNA splicing
2f0030532cellular_componentsmall nuclear ribonucleoprotein complex
2f0034709cellular_componentmethylosome
2f0034719cellular_componentSMN-Sm protein complex
2f0036261biological_process7-methylguanosine cap hypermethylation
2f0043186cellular_componentP granule
2f0046540cellular_componentU4/U6 x U5 tri-snRNP complex
2f0071004cellular_componentU2-type prespliceosome
2f0071005cellular_componentU2-type precatalytic spliceosome
2f0071007cellular_componentU2-type catalytic step 2 spliceosome
2f0071011cellular_componentprecatalytic spliceosome
2f0071013cellular_componentcatalytic step 2 spliceosome
2f0097526cellular_componentspliceosomal tri-snRNP complex
2f1903241biological_processU2-type prespliceosome assembly
2g0000243cellular_componentcommitment complex
2g0000387biological_processspliceosomal snRNP assembly
2g0000398biological_processmRNA splicing, via spliceosome
2g0003723molecular_functionRNA binding
2g0005515molecular_functionprotein binding
2g0005634cellular_componentnucleus
2g0005654cellular_componentnucleoplasm
2g0005681cellular_componentspliceosomal complex
2g0005682cellular_componentU5 snRNP
2g0005683cellular_componentU7 snRNP
2g0005684cellular_componentU2-type spliceosomal complex
2g0005685cellular_componentU1 snRNP
2g0005686cellular_componentU2 snRNP
2g0005687cellular_componentU4 snRNP
2g0005689cellular_componentU12-type spliceosomal complex
2g0005697cellular_componenttelomerase holoenzyme complex
2g0005737cellular_componentcytoplasm
2g0005829cellular_componentcytosol
2g0006396biological_processRNA processing
2g0006397biological_processmRNA processing
2g0006479biological_processprotein methylation
2g0008380biological_processRNA splicing
2g0016604cellular_componentnuclear body
2g0019899molecular_functionenzyme binding
2g0030532cellular_componentsmall nuclear ribonucleoprotein complex
2g0034709cellular_componentmethylosome
2g0034715cellular_componentpICln-Sm protein complex
2g0034719cellular_componentSMN-Sm protein complex
2g0036261biological_process7-methylguanosine cap hypermethylation
2g0046540cellular_componentU4/U6 x U5 tri-snRNP complex
2g0070034molecular_functiontelomerase RNA binding
2g0071005cellular_componentU2-type precatalytic spliceosome
2g0071007cellular_componentU2-type catalytic step 2 spliceosome
2g0071011cellular_componentprecatalytic spliceosome
2g0071013cellular_componentcatalytic step 2 spliceosome
2g0071208molecular_functionhistone pre-mRNA DCP binding
2g0071209molecular_functionU7 snRNA binding
2g0097526cellular_componentspliceosomal tri-snRNP complex
2g1903241biological_processU2-type prespliceosome assembly
2g1990446molecular_functionU1 snRNP binding
4B0000244biological_processspliceosomal tri-snRNP complex assembly
4B0000375biological_processRNA splicing, via transesterification reactions
4B0000398biological_processmRNA splicing, via spliceosome
4B0003723molecular_functionRNA binding
4B0005515molecular_functionprotein binding
4B0005634cellular_componentnucleus
4B0005654cellular_componentnucleoplasm
4B0005681cellular_componentspliceosomal complex
4B0005829cellular_componentcytosol
4B0006397biological_processmRNA processing
4B0008380biological_processRNA splicing
4B0015030cellular_componentCajal body
4B0016607cellular_componentnuclear speck
4B0032991cellular_componentprotein-containing complex
4B0042802molecular_functionidentical protein binding
4B0046540cellular_componentU4/U6 x U5 tri-snRNP complex
4B0071005cellular_componentU2-type precatalytic spliceosome
4C0000375biological_processRNA splicing, via transesterification reactions
4C0000398biological_processmRNA splicing, via spliceosome
4C0005515molecular_functionprotein binding
4C0005634cellular_componentnucleus
4C0005654cellular_componentnucleoplasm
4C0005681cellular_componentspliceosomal complex
4C0006396biological_processRNA processing
4C0006397biological_processmRNA processing
4C0008380biological_processRNA splicing
4C0015030cellular_componentCajal body
4C0016607cellular_componentnuclear speck
4C0017070molecular_functionU6 snRNA binding
4C0030621molecular_functionU4 snRNA binding
4C0046540cellular_componentU4/U6 x U5 tri-snRNP complex
4C0071001cellular_componentU4/U6 snRNP
4C0071005cellular_componentU2-type precatalytic spliceosome
4C0097525cellular_componentspliceosomal snRNP complex
4D0000244biological_processspliceosomal tri-snRNP complex assembly
4D0000398biological_processmRNA splicing, via spliceosome
4D0003723molecular_functionRNA binding
4D0005515molecular_functionprotein binding
4D0005634cellular_componentnucleus
4D0005654cellular_componentnucleoplasm
4D0005681cellular_componentspliceosomal complex
4D0005684cellular_componentU2-type spliceosomal complex
4D0005687cellular_componentU4 snRNP
4D0005690cellular_componentU4atac snRNP
4D0006397biological_processmRNA processing
4D0008380biological_processRNA splicing
4D0015030cellular_componentCajal body
4D0016607cellular_componentnuclear speck
4D0030621molecular_functionU4 snRNA binding
4D0030622molecular_functionU4atac snRNA binding
4D0030674molecular_functionprotein-macromolecule adaptor activity
4D0042802molecular_functionidentical protein binding
4D0043021molecular_functionribonucleoprotein complex binding
4D0046540cellular_componentU4/U6 x U5 tri-snRNP complex
4D0048254biological_processsnoRNA localization
4D0070990molecular_functionsnRNP binding
4D0071005cellular_componentU2-type precatalytic spliceosome
4D0071011cellular_componentprecatalytic spliceosome
4D0071166biological_processribonucleoprotein complex localization
4D0071339cellular_componentMLL1 complex
4D0097526cellular_componentspliceosomal tri-snRNP complex
4E0000398biological_processmRNA splicing, via spliceosome
4E0000492biological_processbox C/D snoRNP assembly
4E0001651cellular_componentdense fibrillar component
4E0003723molecular_functionRNA binding
4E0005515molecular_functionprotein binding
4E0005634cellular_componentnucleus
4E0005654cellular_componentnucleoplasm
4E0005681cellular_componentspliceosomal complex
4E0005690cellular_componentU4atac snRNP
4E0005730cellular_componentnucleolus
4E0006397biological_processmRNA processing
4E0007338biological_processsingle fertilization
4E0008380biological_processRNA splicing
4E0030490biological_processmaturation of SSU-rRNA
4E0030515molecular_functionsnoRNA binding
4E0030621molecular_functionU4 snRNA binding
4E0030622molecular_functionU4atac snRNA binding
4E0031428cellular_componentbox C/D methylation guide snoRNP complex
4E0032040cellular_componentsmall-subunit processome
4E0032991cellular_componentprotein-containing complex
4E0034511molecular_functionU3 snoRNA binding
4E0034512molecular_functionbox C/D sno(s)RNA binding
4E0042254biological_processribosome biogenesis
4E0042274biological_processribosomal small subunit biogenesis
4E0046540cellular_componentU4/U6 x U5 tri-snRNP complex
4E0051117molecular_functionATPase binding
4E0071005cellular_componentU2-type precatalytic spliceosome
4E0071011cellular_componentprecatalytic spliceosome
4E1990904cellular_componentribonucleoprotein complex
4F0000245biological_processspliceosomal complex assembly
4F0000375biological_processRNA splicing, via transesterification reactions
4F0000398biological_processmRNA splicing, via spliceosome
4F0005515molecular_functionprotein binding
4F0005634cellular_componentnucleus
4F0005654cellular_componentnucleoplasm
4F0005681cellular_componentspliceosomal complex
4F0005682cellular_componentU5 snRNP
4F0005829cellular_componentcytosol
4F0006397biological_processmRNA processing
4F0008380biological_processRNA splicing
4F0046540cellular_componentU4/U6 x U5 tri-snRNP complex
4F0051301biological_processcell division
4F0071005cellular_componentU2-type precatalytic spliceosome
4G0000244biological_processspliceosomal tri-snRNP complex assembly
4G0000245biological_processspliceosomal complex assembly
4G0000375biological_processRNA splicing, via transesterification reactions
4G0000398biological_processmRNA splicing, via spliceosome
4G0003723molecular_functionRNA binding
4G0005515molecular_functionprotein binding
4G0005634cellular_componentnucleus
4G0005654cellular_componentnucleoplasm
4G0005681cellular_componentspliceosomal complex
4G0005682cellular_componentU5 snRNP
4G0006396biological_processRNA processing
4G0006397biological_processmRNA processing
4G0006403biological_processRNA localization
4G0008380biological_processRNA splicing
4G0016020cellular_componentmembrane
4G0016607cellular_componentnuclear speck
4G0030674molecular_functionprotein-macromolecule adaptor activity
4G0042802molecular_functionidentical protein binding
4G0043021molecular_functionribonucleoprotein complex binding
4G0045944biological_processpositive regulation of transcription by RNA polymerase II
4G0046540cellular_componentU4/U6 x U5 tri-snRNP complex
4G0071005cellular_componentU2-type precatalytic spliceosome
4G0071013cellular_componentcatalytic step 2 spliceosome
4R0000398biological_processmRNA splicing, via spliceosome
4R0003676molecular_functionnucleic acid binding
4R0003723molecular_functionRNA binding
4R0003729molecular_functionmRNA binding
4R0005515molecular_functionprotein binding
4R0005634cellular_componentnucleus
4R0005654cellular_componentnucleoplasm
4R0005737cellular_componentcytoplasm
4R0046540cellular_componentU4/U6 x U5 tri-snRNP complex
4R0048025biological_processnegative regulation of mRNA splicing, via spliceosome
4S0000387biological_processspliceosomal snRNP assembly
4S0000398biological_processmRNA splicing, via spliceosome
4S0000481biological_processmaturation of 5S rRNA
4S0003723molecular_functionRNA binding
4S0005515molecular_functionprotein binding
4S0005634cellular_componentnucleus
4S0005654cellular_componentnucleoplasm
4S0005681cellular_componentspliceosomal complex
4S0005737cellular_componentcytoplasm
4S0005794cellular_componentGolgi apparatus
4S0005829cellular_componentcytosol
4S0006397biological_processmRNA processing
4S0008380biological_processRNA splicing
4S0015030cellular_componentCajal body
4S0016607cellular_componentnuclear speck
4S0045292biological_processmRNA cis splicing, via spliceosome
4S0045585biological_processpositive regulation of cytotoxic T cell differentiation
4S0046540cellular_componentU4/U6 x U5 tri-snRNP complex
4S0071005cellular_componentU2-type precatalytic spliceosome
4S0071013cellular_componentcatalytic step 2 spliceosome
4T0000245biological_processspliceosomal complex assembly
4T0000398biological_processmRNA splicing, via spliceosome
4T0004843molecular_functioncysteine-type deubiquitinase activity
4T0005515molecular_functionprotein binding
4T0005634cellular_componentnucleus
4T0005654cellular_componentnucleoplasm
4T0005681cellular_componentspliceosomal complex
4T0006397biological_processmRNA processing
4T0008270molecular_functionzinc ion binding
4T0008380biological_processRNA splicing
4T0016579biological_processprotein deubiquitination
4T0016787molecular_functionhydrolase activity
4T0046540cellular_componentU4/U6 x U5 tri-snRNP complex
4T0046872molecular_functionmetal ion binding
4T0051301biological_processcell division
4U0000354biological_processcis assembly of pre-catalytic spliceosome
4U0000375biological_processRNA splicing, via transesterification reactions
4U0000398biological_processmRNA splicing, via spliceosome
4U0000785cellular_componentchromatin
4U0003676molecular_functionnucleic acid binding
4U0003723molecular_functionRNA binding
4U0003724molecular_functionRNA helicase activity
4U0003729molecular_functionmRNA binding
4U0004386molecular_functionhelicase activity
4U0005515molecular_functionprotein binding
4U0005524molecular_functionATP binding
4U0005634cellular_componentnucleus
4U0005654cellular_componentnucleoplasm
4U0005681cellular_componentspliceosomal complex
4U0005682cellular_componentU5 snRNP
4U0005694cellular_componentchromosome
4U0005730cellular_componentnucleolus
4U0006397biological_processmRNA processing
4U0008380biological_processRNA splicing
4U0016787molecular_functionhydrolase activity
4U0016887molecular_functionATP hydrolysis activity
4U0046540cellular_componentU4/U6 x U5 tri-snRNP complex
4U0062176biological_processR-loop processing
4U0070062cellular_componentextracellular exosome
4U0071013cellular_componentcatalytic step 2 spliceosome
4X0000398biological_processmRNA splicing, via spliceosome
4X0003676molecular_functionnucleic acid binding
4X0005515molecular_functionprotein binding
4X0005575cellular_componentcellular_component
4X0005634cellular_componentnucleus
4X0005654cellular_componentnucleoplasm
4X0006397biological_processmRNA processing
4X0008150biological_processbiological_process
4X0008380biological_processRNA splicing
4X0046540cellular_componentU4/U6 x U5 tri-snRNP complex
4Y0000244biological_processspliceosomal tri-snRNP complex assembly
4Y0000387biological_processspliceosomal snRNP assembly
4Y0000398biological_processmRNA splicing, via spliceosome
4Y0000775cellular_componentchromosome, centromeric region
4Y0000776cellular_componentkinetochore
4Y0003723molecular_functionRNA binding
4Y0004672molecular_functionprotein kinase activity
4Y0004674molecular_functionprotein serine/threonine kinase activity
4Y0005515molecular_functionprotein binding
4Y0005524molecular_functionATP binding
4Y0005634cellular_componentnucleus
4Y0005654cellular_componentnucleoplasm
4Y0005681cellular_componentspliceosomal complex
4Y0005694cellular_componentchromosome
4Y0006338biological_processchromatin remodeling
4Y0006397biological_processmRNA processing
4Y0006468biological_processprotein phosphorylation
4Y0008380biological_processRNA splicing
4Y0016310biological_processphosphorylation
4Y0016607cellular_componentnuclear speck
4Y0035332biological_processpositive regulation of hippo signaling
4Y0044024molecular_functionhistone H2AS1 kinase activity
4Y0045292biological_processmRNA cis splicing, via spliceosome
4Y0046827biological_processpositive regulation of protein export from nucleus
4Y0071013cellular_componentcatalytic step 2 spliceosome
4Y0090266biological_processregulation of mitotic cell cycle spindle assembly checkpoint
4Y0106310molecular_functionprotein serine kinase activity
4a0000387biological_processspliceosomal snRNP assembly
4a0000398biological_processmRNA splicing, via spliceosome
4a0003723molecular_functionRNA binding
4a0005515molecular_functionprotein binding
4a0005634cellular_componentnucleus
4a0005654cellular_componentnucleoplasm
4a0005681cellular_componentspliceosomal complex
4a0005682cellular_componentU5 snRNP
4a0005683cellular_componentU7 snRNP
4a0005684cellular_componentU2-type spliceosomal complex
4a0005685cellular_componentU1 snRNP
4a0005686cellular_componentU2 snRNP
4a0005687cellular_componentU4 snRNP
4a0005689cellular_componentU12-type spliceosomal complex
4a0005697cellular_componenttelomerase holoenzyme complex
4a0005737cellular_componentcytoplasm
4a0005829cellular_componentcytosol
4a0006397biological_processmRNA processing
4a0006479biological_processprotein methylation
4a0008380biological_processRNA splicing
4a0030532cellular_componentsmall nuclear ribonucleoprotein complex
4a0034709cellular_componentmethylosome
4a0034719cellular_componentSMN-Sm protein complex
4a0036261biological_process7-methylguanosine cap hypermethylation
4a0046540cellular_componentU4/U6 x U5 tri-snRNP complex
4a0070034molecular_functiontelomerase RNA binding
4a0070990molecular_functionsnRNP binding
4a0071004cellular_componentU2-type prespliceosome
4a0071005cellular_componentU2-type precatalytic spliceosome
4a0071007cellular_componentU2-type catalytic step 2 spliceosome
4a0071013cellular_componentcatalytic step 2 spliceosome
4a0071204cellular_componenthistone pre-mRNA 3'end processing complex
4a0071208molecular_functionhistone pre-mRNA DCP binding
4a1903241biological_processU2-type prespliceosome assembly
4a1990446molecular_functionU1 snRNP binding
4a1990447molecular_functionU2 snRNP binding
4b0000243cellular_componentcommitment complex
4b0000245biological_processspliceosomal complex assembly
4b0000387biological_processspliceosomal snRNP assembly
4b0000398biological_processmRNA splicing, via spliceosome
4b0003723molecular_functionRNA binding
4b0005515molecular_functionprotein binding
4b0005634cellular_componentnucleus
4b0005654cellular_componentnucleoplasm
4b0005681cellular_componentspliceosomal complex
4b0005682cellular_componentU5 snRNP
4b0005684cellular_componentU2-type spliceosomal complex
4b0005685cellular_componentU1 snRNP
4b0005686cellular_componentU2 snRNP
4b0005687cellular_componentU4 snRNP
4b0005689cellular_componentU12-type spliceosomal complex
4b0005737cellular_componentcytoplasm
4b0005829cellular_componentcytosol
4b0006396biological_processRNA processing
4b0006397biological_processmRNA processing
4b0008380biological_processRNA splicing
4b0030532cellular_componentsmall nuclear ribonucleoprotein complex
4b0034709cellular_componentmethylosome
4b0034715cellular_componentpICln-Sm protein complex
4b0034719cellular_componentSMN-Sm protein complex
4b0036261biological_process7-methylguanosine cap hypermethylation
4b0046540cellular_componentU4/U6 x U5 tri-snRNP complex
4b0071005cellular_componentU2-type precatalytic spliceosome
4b0071007cellular_componentU2-type catalytic step 2 spliceosome
4b0071011cellular_componentprecatalytic spliceosome
4b0071013cellular_componentcatalytic step 2 spliceosome
4b0097526cellular_componentspliceosomal tri-snRNP complex
4b1903241biological_processU2-type prespliceosome assembly
4c0000245biological_processspliceosomal complex assembly
4c0000387biological_processspliceosomal snRNP assembly
4c0000398biological_processmRNA splicing, via spliceosome
4c0003723molecular_functionRNA binding
4c0005515molecular_functionprotein binding
4c0005634cellular_componentnucleus
4c0005654cellular_componentnucleoplasm
4c0005681cellular_componentspliceosomal complex
4c0005682cellular_componentU5 snRNP
4c0005684cellular_componentU2-type spliceosomal complex
4c0005685cellular_componentU1 snRNP
4c0005686cellular_componentU2 snRNP
4c0005687cellular_componentU4 snRNP
4c0005689cellular_componentU12-type spliceosomal complex
4c0005737cellular_componentcytoplasm
4c0005829cellular_componentcytosol
4c0006397biological_processmRNA processing
4c0008380biological_processRNA splicing
4c0030532cellular_componentsmall nuclear ribonucleoprotein complex
4c0034709cellular_componentmethylosome
4c0034715cellular_componentpICln-Sm protein complex
4c0034719cellular_componentSMN-Sm protein complex
4c0036261biological_process7-methylguanosine cap hypermethylation
4c0046540cellular_componentU4/U6 x U5 tri-snRNP complex
4c0070062cellular_componentextracellular exosome
4c0071005cellular_componentU2-type precatalytic spliceosome
4c0071007cellular_componentU2-type catalytic step 2 spliceosome
4c0071011cellular_componentprecatalytic spliceosome
4c0071013cellular_componentcatalytic step 2 spliceosome
4c1903241biological_processU2-type prespliceosome assembly
4d0000387biological_processspliceosomal snRNP assembly
4d0000398biological_processmRNA splicing, via spliceosome
4d0003723molecular_functionRNA binding
4d0005515molecular_functionprotein binding
4d0005634cellular_componentnucleus
4d0005654cellular_componentnucleoplasm
4d0005681cellular_componentspliceosomal complex
4d0005682cellular_componentU5 snRNP
4d0005683cellular_componentU7 snRNP
4d0005684cellular_componentU2-type spliceosomal complex
4d0005685cellular_componentU1 snRNP
4d0005686cellular_componentU2 snRNP
4d0005687cellular_componentU4 snRNP
4d0005689cellular_componentU12-type spliceosomal complex
4d0005737cellular_componentcytoplasm
4d0005829cellular_componentcytosol
4d0006397biological_processmRNA processing
4d0008380biological_processRNA splicing
4d0030532cellular_componentsmall nuclear ribonucleoprotein complex
4d0034709cellular_componentmethylosome
4d0034715cellular_componentpICln-Sm protein complex
4d0034719cellular_componentSMN-Sm protein complex
4d0036261biological_process7-methylguanosine cap hypermethylation
4d0046540cellular_componentU4/U6 x U5 tri-snRNP complex
4d0071005cellular_componentU2-type precatalytic spliceosome
4d0071007cellular_componentU2-type catalytic step 2 spliceosome
4d0071013cellular_componentcatalytic step 2 spliceosome
4d0120114cellular_componentSm-like protein family complex
4d1903241biological_processU2-type prespliceosome assembly
4e0000245biological_processspliceosomal complex assembly
4e0000387biological_processspliceosomal snRNP assembly
4e0000398biological_processmRNA splicing, via spliceosome
4e0003723molecular_functionRNA binding
4e0005515molecular_functionprotein binding
4e0005634cellular_componentnucleus
4e0005654cellular_componentnucleoplasm
4e0005681cellular_componentspliceosomal complex
4e0005682cellular_componentU5 snRNP
4e0005683cellular_componentU7 snRNP
4e0005684cellular_componentU2-type spliceosomal complex
4e0005685cellular_componentU1 snRNP
4e0005686cellular_componentU2 snRNP
4e0005687cellular_componentU4 snRNP
4e0005689cellular_componentU12-type spliceosomal complex
4e0005697cellular_componenttelomerase holoenzyme complex
4e0005737cellular_componentcytoplasm
4e0005829cellular_componentcytosol
4e0006397biological_processmRNA processing
4e0008380biological_processRNA splicing
4e0030532cellular_componentsmall nuclear ribonucleoprotein complex
4e0034709cellular_componentmethylosome
4e0034715cellular_componentpICln-Sm protein complex
4e0034719cellular_componentSMN-Sm protein complex
4e0036261biological_process7-methylguanosine cap hypermethylation
4e0046540cellular_componentU4/U6 x U5 tri-snRNP complex
4e0071005cellular_componentU2-type precatalytic spliceosome
4e0071007cellular_componentU2-type catalytic step 2 spliceosome
4e0071011cellular_componentprecatalytic spliceosome
4e0071013cellular_componentcatalytic step 2 spliceosome
4e1903241biological_processU2-type prespliceosome assembly
4f0000245biological_processspliceosomal complex assembly
4f0000387biological_processspliceosomal snRNP assembly
4f0000398biological_processmRNA splicing, via spliceosome
4f0003723molecular_functionRNA binding
4f0005515molecular_functionprotein binding
4f0005634cellular_componentnucleus
4f0005654cellular_componentnucleoplasm
4f0005681cellular_componentspliceosomal complex
4f0005682cellular_componentU5 snRNP
4f0005683cellular_componentU7 snRNP
4f0005684cellular_componentU2-type spliceosomal complex
4f0005685cellular_componentU1 snRNP
4f0005686cellular_componentU2 snRNP
4f0005687cellular_componentU4 snRNP
4f0005689cellular_componentU12-type spliceosomal complex
4f0005737cellular_componentcytoplasm
4f0005829cellular_componentcytosol
4f0006397biological_processmRNA processing
4f0008380biological_processRNA splicing
4f0030532cellular_componentsmall nuclear ribonucleoprotein complex
4f0034709cellular_componentmethylosome
4f0034719cellular_componentSMN-Sm protein complex
4f0036261biological_process7-methylguanosine cap hypermethylation
4f0043186cellular_componentP granule
4f0046540cellular_componentU4/U6 x U5 tri-snRNP complex
4f0071004cellular_componentU2-type prespliceosome
4f0071005cellular_componentU2-type precatalytic spliceosome
4f0071007cellular_componentU2-type catalytic step 2 spliceosome
4f0071011cellular_componentprecatalytic spliceosome
4f0071013cellular_componentcatalytic step 2 spliceosome
4f0097526cellular_componentspliceosomal tri-snRNP complex
4f1903241biological_processU2-type prespliceosome assembly
4g0000243cellular_componentcommitment complex
4g0000387biological_processspliceosomal snRNP assembly
4g0000398biological_processmRNA splicing, via spliceosome
4g0003723molecular_functionRNA binding
4g0005515molecular_functionprotein binding
4g0005634cellular_componentnucleus
4g0005654cellular_componentnucleoplasm
4g0005681cellular_componentspliceosomal complex
4g0005682cellular_componentU5 snRNP
4g0005683cellular_componentU7 snRNP
4g0005684cellular_componentU2-type spliceosomal complex
4g0005685cellular_componentU1 snRNP
4g0005686cellular_componentU2 snRNP
4g0005687cellular_componentU4 snRNP
4g0005689cellular_componentU12-type spliceosomal complex
4g0005697cellular_componenttelomerase holoenzyme complex
4g0005737cellular_componentcytoplasm
4g0005829cellular_componentcytosol
4g0006396biological_processRNA processing
4g0006397biological_processmRNA processing
4g0006479biological_processprotein methylation
4g0008380biological_processRNA splicing
4g0016604cellular_componentnuclear body
4g0019899molecular_functionenzyme binding
4g0030532cellular_componentsmall nuclear ribonucleoprotein complex
4g0034709cellular_componentmethylosome
4g0034715cellular_componentpICln-Sm protein complex
4g0034719cellular_componentSMN-Sm protein complex
4g0036261biological_process7-methylguanosine cap hypermethylation
4g0046540cellular_componentU4/U6 x U5 tri-snRNP complex
4g0070034molecular_functiontelomerase RNA binding
4g0071005cellular_componentU2-type precatalytic spliceosome
4g0071007cellular_componentU2-type catalytic step 2 spliceosome
4g0071011cellular_componentprecatalytic spliceosome
4g0071013cellular_componentcatalytic step 2 spliceosome
4g0071208molecular_functionhistone pre-mRNA DCP binding
4g0071209molecular_functionU7 snRNA binding
4g0097526cellular_componentspliceosomal tri-snRNP complex
4g1903241biological_processU2-type prespliceosome assembly
4g1990446molecular_functionU1 snRNP binding
5B0000244biological_processspliceosomal tri-snRNP complex assembly
5B0000375biological_processRNA splicing, via transesterification reactions
5B0000398biological_processmRNA splicing, via spliceosome
5B0003723molecular_functionRNA binding
5B0005515molecular_functionprotein binding
5B0005634cellular_componentnucleus
5B0005654cellular_componentnucleoplasm
5B0005681cellular_componentspliceosomal complex
5B0005682cellular_componentU5 snRNP
5B0006397biological_processmRNA processing
5B0008233molecular_functionpeptidase activity
5B0008237molecular_functionmetallopeptidase activity
5B0008380biological_processRNA splicing
5B0016020cellular_componentmembrane
5B0016607cellular_componentnuclear speck
5B0017070molecular_functionU6 snRNA binding
5B0030532cellular_componentsmall nuclear ribonucleoprotein complex
5B0030619molecular_functionU1 snRNA binding
5B0030620molecular_functionU2 snRNA binding
5B0030623molecular_functionU5 snRNA binding
5B0046540cellular_componentU4/U6 x U5 tri-snRNP complex
5B0070530molecular_functionK63-linked polyubiquitin modification-dependent protein binding
5B0071005cellular_componentU2-type precatalytic spliceosome
5B0071006cellular_componentU2-type catalytic step 1 spliceosome
5B0071007cellular_componentU2-type catalytic step 2 spliceosome
5B0071013cellular_componentcatalytic step 2 spliceosome
5B0071222biological_processcellular response to lipopolysaccharide
5B0071356biological_processcellular response to tumor necrosis factor
5B0097157molecular_functionpre-mRNA intronic binding
5B0140492molecular_functionmetal-dependent deubiquitinase activity
5C0000398biological_processmRNA splicing, via spliceosome
5C0003723molecular_functionRNA binding
5C0003924molecular_functionGTPase activity
5C0005515molecular_functionprotein binding
5C0005525molecular_functionGTP binding
5C0005634cellular_componentnucleus
5C0005654cellular_componentnucleoplasm
5C0005681cellular_componentspliceosomal complex
5C0005829cellular_componentcytosol
5C0006397biological_processmRNA processing
5C0008380biological_processRNA splicing
5C0015030cellular_componentCajal body
5C0016020cellular_componentmembrane
5C0016607cellular_componentnuclear speck
5C0030623molecular_functionU5 snRNA binding
5C0042220biological_processresponse to cocaine
5C0043231cellular_componentintracellular membrane-bounded organelle
5C0046540cellular_componentU4/U6 x U5 tri-snRNP complex
5C0071005cellular_componentU2-type precatalytic spliceosome
5C0071007cellular_componentU2-type catalytic step 2 spliceosome
5C0071013cellular_componentcatalytic step 2 spliceosome
5C0071466biological_processcellular response to xenobiotic stimulus
5D0000354biological_processcis assembly of pre-catalytic spliceosome
5D0000388biological_processspliceosome conformational change to release U4 (or U4atac) and U1 (or U11)
5D0000398biological_processmRNA splicing, via spliceosome
5D0001649biological_processosteoblast differentiation
5D0003676molecular_functionnucleic acid binding
5D0003723molecular_functionRNA binding
5D0003724molecular_functionRNA helicase activity
5D0004386molecular_functionhelicase activity
5D0005515molecular_functionprotein binding
5D0005524molecular_functionATP binding
5D0005634cellular_componentnucleus
5D0005654cellular_componentnucleoplasm
5D0005681cellular_componentspliceosomal complex
5D0005682cellular_componentU5 snRNP
5D0006397biological_processmRNA processing
5D0008380biological_processRNA splicing
5D0016020cellular_componentmembrane
5D0016787molecular_functionhydrolase activity
5D0016887molecular_functionATP hydrolysis activity
5D0042802molecular_functionidentical protein binding
5D0046540cellular_componentU4/U6 x U5 tri-snRNP complex
5D0071005cellular_componentU2-type precatalytic spliceosome
5D0071006cellular_componentU2-type catalytic step 1 spliceosome
5D0071013cellular_componentcatalytic step 2 spliceosome
5E0000375biological_processRNA splicing, via transesterification reactions
5E0000398biological_processmRNA splicing, via spliceosome
5E0003723molecular_functionRNA binding
5E0005515molecular_functionprotein binding
5E0005634cellular_componentnucleus
5E0005654cellular_componentnucleoplasm
5E0005681cellular_componentspliceosomal complex
5E0005682cellular_componentU5 snRNP
5E0005732cellular_componentsno(s)RNA-containing ribonucleoprotein complex
5E0005829cellular_componentcytosol
5E0006396biological_processRNA processing
5E0006397biological_processmRNA processing
5E0008380biological_processRNA splicing
5E0016607cellular_componentnuclear speck
5E0046540cellular_componentU4/U6 x U5 tri-snRNP complex
5E0071007cellular_componentU2-type catalytic step 2 spliceosome
5E0071013cellular_componentcatalytic step 2 spliceosome
5a0000387biological_processspliceosomal snRNP assembly
5a0000398biological_processmRNA splicing, via spliceosome
5a0003723molecular_functionRNA binding
5a0005515molecular_functionprotein binding
5a0005634cellular_componentnucleus
5a0005654cellular_componentnucleoplasm
5a0005681cellular_componentspliceosomal complex
5a0005682cellular_componentU5 snRNP
5a0005683cellular_componentU7 snRNP
5a0005684cellular_componentU2-type spliceosomal complex
5a0005685cellular_componentU1 snRNP
5a0005686cellular_componentU2 snRNP
5a0005687cellular_componentU4 snRNP
5a0005689cellular_componentU12-type spliceosomal complex
5a0005697cellular_componenttelomerase holoenzyme complex
5a0005737cellular_componentcytoplasm
5a0005829cellular_componentcytosol
5a0006397biological_processmRNA processing
5a0006479biological_processprotein methylation
5a0008380biological_processRNA splicing
5a0030532cellular_componentsmall nuclear ribonucleoprotein complex
5a0034709cellular_componentmethylosome
5a0034719cellular_componentSMN-Sm protein complex
5a0036261biological_process7-methylguanosine cap hypermethylation
5a0046540cellular_componentU4/U6 x U5 tri-snRNP complex
5a0070034molecular_functiontelomerase RNA binding
5a0070990molecular_functionsnRNP binding
5a0071004cellular_componentU2-type prespliceosome
5a0071005cellular_componentU2-type precatalytic spliceosome
5a0071007cellular_componentU2-type catalytic step 2 spliceosome
5a0071013cellular_componentcatalytic step 2 spliceosome
5a0071204cellular_componenthistone pre-mRNA 3'end processing complex
5a0071208molecular_functionhistone pre-mRNA DCP binding
5a1903241biological_processU2-type prespliceosome assembly
5a1990446molecular_functionU1 snRNP binding
5a1990447molecular_functionU2 snRNP binding
5b0000243cellular_componentcommitment complex
5b0000245biological_processspliceosomal complex assembly
5b0000387biological_processspliceosomal snRNP assembly
5b0000398biological_processmRNA splicing, via spliceosome
5b0003723molecular_functionRNA binding
5b0005515molecular_functionprotein binding
5b0005634cellular_componentnucleus
5b0005654cellular_componentnucleoplasm
5b0005681cellular_componentspliceosomal complex
5b0005682cellular_componentU5 snRNP
5b0005684cellular_componentU2-type spliceosomal complex
5b0005685cellular_componentU1 snRNP
5b0005686cellular_componentU2 snRNP
5b0005687cellular_componentU4 snRNP
5b0005689cellular_componentU12-type spliceosomal complex
5b0005737cellular_componentcytoplasm
5b0005829cellular_componentcytosol
5b0006396biological_processRNA processing
5b0006397biological_processmRNA processing
5b0008380biological_processRNA splicing
5b0030532cellular_componentsmall nuclear ribonucleoprotein complex
5b0034709cellular_componentmethylosome
5b0034715cellular_componentpICln-Sm protein complex
5b0034719cellular_componentSMN-Sm protein complex
5b0036261biological_process7-methylguanosine cap hypermethylation
5b0046540cellular_componentU4/U6 x U5 tri-snRNP complex
5b0071005cellular_componentU2-type precatalytic spliceosome
5b0071007cellular_componentU2-type catalytic step 2 spliceosome
5b0071011cellular_componentprecatalytic spliceosome
5b0071013cellular_componentcatalytic step 2 spliceosome
5b0097526cellular_componentspliceosomal tri-snRNP complex
5b1903241biological_processU2-type prespliceosome assembly
5c0000245biological_processspliceosomal complex assembly
5c0000387biological_processspliceosomal snRNP assembly
5c0000398biological_processmRNA splicing, via spliceosome
5c0003723molecular_functionRNA binding
5c0005515molecular_functionprotein binding
5c0005634cellular_componentnucleus
5c0005654cellular_componentnucleoplasm
5c0005681cellular_componentspliceosomal complex
5c0005682cellular_componentU5 snRNP
5c0005684cellular_componentU2-type spliceosomal complex
5c0005685cellular_componentU1 snRNP
5c0005686cellular_componentU2 snRNP
5c0005687cellular_componentU4 snRNP
5c0005689cellular_componentU12-type spliceosomal complex
5c0005737cellular_componentcytoplasm
5c0005829cellular_componentcytosol
5c0006397biological_processmRNA processing
5c0008380biological_processRNA splicing
5c0030532cellular_componentsmall nuclear ribonucleoprotein complex
5c0034709cellular_componentmethylosome
5c0034715cellular_componentpICln-Sm protein complex
5c0034719cellular_componentSMN-Sm protein complex
5c0036261biological_process7-methylguanosine cap hypermethylation
5c0046540cellular_componentU4/U6 x U5 tri-snRNP complex
5c0070062cellular_componentextracellular exosome
5c0071005cellular_componentU2-type precatalytic spliceosome
5c0071007cellular_componentU2-type catalytic step 2 spliceosome
5c0071011cellular_componentprecatalytic spliceosome
5c0071013cellular_componentcatalytic step 2 spliceosome
5c1903241biological_processU2-type prespliceosome assembly
5d0000387biological_processspliceosomal snRNP assembly
5d0000398biological_processmRNA splicing, via spliceosome
5d0003723molecular_functionRNA binding
5d0005515molecular_functionprotein binding
5d0005634cellular_componentnucleus
5d0005654cellular_componentnucleoplasm
5d0005681cellular_componentspliceosomal complex
5d0005682cellular_componentU5 snRNP
5d0005683cellular_componentU7 snRNP
5d0005684cellular_componentU2-type spliceosomal complex
5d0005685cellular_componentU1 snRNP
5d0005686cellular_componentU2 snRNP
5d0005687cellular_componentU4 snRNP
5d0005689cellular_componentU12-type spliceosomal complex
5d0005737cellular_componentcytoplasm
5d0005829cellular_componentcytosol
5d0006397biological_processmRNA processing
5d0008380biological_processRNA splicing
5d0030532cellular_componentsmall nuclear ribonucleoprotein complex
5d0034709cellular_componentmethylosome
5d0034715cellular_componentpICln-Sm protein complex
5d0034719cellular_componentSMN-Sm protein complex
5d0036261biological_process7-methylguanosine cap hypermethylation
5d0046540cellular_componentU4/U6 x U5 tri-snRNP complex
5d0071005cellular_componentU2-type precatalytic spliceosome
5d0071007cellular_componentU2-type catalytic step 2 spliceosome
5d0071013cellular_componentcatalytic step 2 spliceosome
5d0120114cellular_componentSm-like protein family complex
5d1903241biological_processU2-type prespliceosome assembly
5e0000245biological_processspliceosomal complex assembly
5e0000387biological_processspliceosomal snRNP assembly
5e0000398biological_processmRNA splicing, via spliceosome
5e0003723molecular_functionRNA binding
5e0005515molecular_functionprotein binding
5e0005634cellular_componentnucleus
5e0005654cellular_componentnucleoplasm
5e0005681cellular_componentspliceosomal complex
5e0005682cellular_componentU5 snRNP
5e0005683cellular_componentU7 snRNP
5e0005684cellular_componentU2-type spliceosomal complex
5e0005685cellular_componentU1 snRNP
5e0005686cellular_componentU2 snRNP
5e0005687cellular_componentU4 snRNP
5e0005689cellular_componentU12-type spliceosomal complex
5e0005697cellular_componenttelomerase holoenzyme complex
5e0005737cellular_componentcytoplasm
5e0005829cellular_componentcytosol
5e0006397biological_processmRNA processing
5e0008380biological_processRNA splicing
5e0030532cellular_componentsmall nuclear ribonucleoprotein complex
5e0034709cellular_componentmethylosome
5e0034715cellular_componentpICln-Sm protein complex
5e0034719cellular_componentSMN-Sm protein complex
5e0036261biological_process7-methylguanosine cap hypermethylation
5e0046540cellular_componentU4/U6 x U5 tri-snRNP complex
5e0071005cellular_componentU2-type precatalytic spliceosome
5e0071007cellular_componentU2-type catalytic step 2 spliceosome
5e0071011cellular_componentprecatalytic spliceosome
5e0071013cellular_componentcatalytic step 2 spliceosome
5e1903241biological_processU2-type prespliceosome assembly
5f0000245biological_processspliceosomal complex assembly
5f0000387biological_processspliceosomal snRNP assembly
5f0000398biological_processmRNA splicing, via spliceosome
5f0003723molecular_functionRNA binding
5f0005515molecular_functionprotein binding
5f0005634cellular_componentnucleus
5f0005654cellular_componentnucleoplasm
5f0005681cellular_componentspliceosomal complex
5f0005682cellular_componentU5 snRNP
5f0005683cellular_componentU7 snRNP
5f0005684cellular_componentU2-type spliceosomal complex
5f0005685cellular_componentU1 snRNP
5f0005686cellular_componentU2 snRNP
5f0005687cellular_componentU4 snRNP
5f0005689cellular_componentU12-type spliceosomal complex
5f0005737cellular_componentcytoplasm
5f0005829cellular_componentcytosol
5f0006397biological_processmRNA processing
5f0008380biological_processRNA splicing
5f0030532cellular_componentsmall nuclear ribonucleoprotein complex
5f0034709cellular_componentmethylosome
5f0034719cellular_componentSMN-Sm protein complex
5f0036261biological_process7-methylguanosine cap hypermethylation
5f0043186cellular_componentP granule
5f0046540cellular_componentU4/U6 x U5 tri-snRNP complex
5f0071004cellular_componentU2-type prespliceosome
5f0071005cellular_componentU2-type precatalytic spliceosome
5f0071007cellular_componentU2-type catalytic step 2 spliceosome
5f0071011cellular_componentprecatalytic spliceosome
5f0071013cellular_componentcatalytic step 2 spliceosome
5f0097526cellular_componentspliceosomal tri-snRNP complex
5f1903241biological_processU2-type prespliceosome assembly
5g0000243cellular_componentcommitment complex
5g0000387biological_processspliceosomal snRNP assembly
5g0000398biological_processmRNA splicing, via spliceosome
5g0003723molecular_functionRNA binding
5g0005515molecular_functionprotein binding
5g0005634cellular_componentnucleus
5g0005654cellular_componentnucleoplasm
5g0005681cellular_componentspliceosomal complex
5g0005682cellular_componentU5 snRNP
5g0005683cellular_componentU7 snRNP
5g0005684cellular_componentU2-type spliceosomal complex
5g0005685cellular_componentU1 snRNP
5g0005686cellular_componentU2 snRNP
5g0005687cellular_componentU4 snRNP
5g0005689cellular_componentU12-type spliceosomal complex
5g0005697cellular_componenttelomerase holoenzyme complex
5g0005737cellular_componentcytoplasm
5g0005829cellular_componentcytosol
5g0006396biological_processRNA processing
5g0006397biological_processmRNA processing
5g0006479biological_processprotein methylation
5g0008380biological_processRNA splicing
5g0016604cellular_componentnuclear body
5g0019899molecular_functionenzyme binding
5g0030532cellular_componentsmall nuclear ribonucleoprotein complex
5g0034709cellular_componentmethylosome
5g0034715cellular_componentpICln-Sm protein complex
5g0034719cellular_componentSMN-Sm protein complex
5g0036261biological_process7-methylguanosine cap hypermethylation
5g0046540cellular_componentU4/U6 x U5 tri-snRNP complex
5g0070034molecular_functiontelomerase RNA binding
5g0071005cellular_componentU2-type precatalytic spliceosome
5g0071007cellular_componentU2-type catalytic step 2 spliceosome
5g0071011cellular_componentprecatalytic spliceosome
5g0071013cellular_componentcatalytic step 2 spliceosome
5g0071208molecular_functionhistone pre-mRNA DCP binding
5g0071209molecular_functionU7 snRNA binding
5g0097526cellular_componentspliceosomal tri-snRNP complex
5g1903241biological_processU2-type prespliceosome assembly
5g1990446molecular_functionU1 snRNP binding
6a0000244biological_processspliceosomal tri-snRNP complex assembly
6a0000398biological_processmRNA splicing, via spliceosome
6a0000932cellular_componentP-body
6a0003723molecular_functionRNA binding
6a0005515molecular_functionprotein binding
6a0005634cellular_componentnucleus
6a0005654cellular_componentnucleoplasm
6a0005681cellular_componentspliceosomal complex
6a0005688cellular_componentU6 snRNP
6a0005737cellular_componentcytoplasm
6a0005829cellular_componentcytosol
6a0006397biological_processmRNA processing
6a0006402biological_processmRNA catabolic process
6a0008380biological_processRNA splicing
6a0017070molecular_functionU6 snRNA binding
6a0031267molecular_functionsmall GTPase binding
6a0046540cellular_componentU4/U6 x U5 tri-snRNP complex
6a0071005cellular_componentU2-type precatalytic spliceosome
6a0071011cellular_componentprecatalytic spliceosome
6a0071013cellular_componentcatalytic step 2 spliceosome
6a0120115cellular_componentLsm2-8 complex
6a1990726cellular_componentLsm1-7-Pat1 complex
6b0000398biological_processmRNA splicing, via spliceosome
6b0000932cellular_componentP-body
6b0003723molecular_functionRNA binding
6b0005515molecular_functionprotein binding
6b0005634cellular_componentnucleus
6b0005654cellular_componentnucleoplasm
6b0005681cellular_componentspliceosomal complex
6b0005688cellular_componentU6 snRNP
6b0005829cellular_componentcytosol
6b0006397biological_processmRNA processing
6b0008380biological_processRNA splicing
6b0030629molecular_functionU6 snRNA 3'-end binding
6b0032991cellular_componentprotein-containing complex
6b0033962biological_processP-body assembly
6b0046540cellular_componentU4/U6 x U5 tri-snRNP complex
6b0071005cellular_componentU2-type precatalytic spliceosome
6b0071011cellular_componentprecatalytic spliceosome
6b0071013cellular_componentcatalytic step 2 spliceosome
6b0120115cellular_componentLsm2-8 complex
6b1990726cellular_componentLsm1-7-Pat1 complex
6c0000387biological_processspliceosomal snRNP assembly
6c0000398biological_processmRNA splicing, via spliceosome
6c0000932cellular_componentP-body
6c0000956biological_processnuclear-transcribed mRNA catabolic process
6c0003723molecular_functionRNA binding
6c0005515molecular_functionprotein binding
6c0005634cellular_componentnucleus
6c0005654cellular_componentnucleoplasm
6c0005681cellular_componentspliceosomal complex
6c0005688cellular_componentU6 snRNP
6c0005829cellular_componentcytosol
6c0006396biological_processRNA processing
6c0006397biological_processmRNA processing
6c0008380biological_processRNA splicing
6c0016020cellular_componentmembrane
6c0017070molecular_functionU6 snRNA binding
6c0032991cellular_componentprotein-containing complex
6c0033962biological_processP-body assembly
6c0042731molecular_functionPH domain binding
6c0046540cellular_componentU4/U6 x U5 tri-snRNP complex
6c0071005cellular_componentU2-type precatalytic spliceosome
6c0097526cellular_componentspliceosomal tri-snRNP complex
6c0120115cellular_componentLsm2-8 complex
6d0000398biological_processmRNA splicing, via spliceosome
6d0003723molecular_functionRNA binding
6d0005515molecular_functionprotein binding
6d0005634cellular_componentnucleus
6d0005654cellular_componentnucleoplasm
6d0005681cellular_componentspliceosomal complex
6d0005688cellular_componentU6 snRNP
6d0005737cellular_componentcytoplasm
6d0005829cellular_componentcytosol
6d0006397biological_processmRNA processing
6d0006402biological_processmRNA catabolic process
6d0008380biological_processRNA splicing
6d0009617biological_processresponse to bacterium
6d0046540cellular_componentU4/U6 x U5 tri-snRNP complex
6d0046982molecular_functionprotein heterodimerization activity
6d0071005cellular_componentU2-type precatalytic spliceosome
6d0120115cellular_componentLsm2-8 complex
6d1990726cellular_componentLsm1-7-Pat1 complex
6e0000398biological_processmRNA splicing, via spliceosome
6e0000932cellular_componentP-body
6e0003723molecular_functionRNA binding
6e0005515molecular_functionprotein binding
6e0005634cellular_componentnucleus
6e0005654cellular_componentnucleoplasm
6e0005681cellular_componentspliceosomal complex
6e0005688cellular_componentU6 snRNP
6e0005730cellular_componentnucleolus
6e0005732cellular_componentsno(s)RNA-containing ribonucleoprotein complex
6e0005737cellular_componentcytoplasm
6e0005829cellular_componentcytosol
6e0006364biological_processrRNA processing
6e0006397biological_processmRNA processing
6e0006402biological_processmRNA catabolic process
6e0008033biological_processtRNA processing
6e0008380biological_processRNA splicing
6e0030490biological_processmaturation of SSU-rRNA
6e0030532cellular_componentsmall nuclear ribonucleoprotein complex
6e0046540cellular_componentU4/U6 x U5 tri-snRNP complex
6e0046982molecular_functionprotein heterodimerization activity
6e0071005cellular_componentU2-type precatalytic spliceosome
6e0120114cellular_componentSm-like protein family complex
6e0120115cellular_componentLsm2-8 complex
6f0000398biological_processmRNA splicing, via spliceosome
6f0000956biological_processnuclear-transcribed mRNA catabolic process
6f0003723molecular_functionRNA binding
6f0005515molecular_functionprotein binding
6f0005634cellular_componentnucleus
6f0005654cellular_componentnucleoplasm
6f0005681cellular_componentspliceosomal complex
6f0005688cellular_componentU6 snRNP
6f0005689cellular_componentU12-type spliceosomal complex
6f0005829cellular_componentcytosol
6f0006397biological_processmRNA processing
6f0008380biological_processRNA splicing
6f0017070molecular_functionU6 snRNA binding
6f0046540cellular_componentU4/U6 x U5 tri-snRNP complex
6f0071004cellular_componentU2-type prespliceosome
6f0071005cellular_componentU2-type precatalytic spliceosome
6f0071013cellular_componentcatalytic step 2 spliceosome
6f0097526cellular_componentspliceosomal tri-snRNP complex
6f0120115cellular_componentLsm2-8 complex
6f1990726cellular_componentLsm1-7-Pat1 complex
6g0000398biological_processmRNA splicing, via spliceosome
6g0003723molecular_functionRNA binding
6g0003729molecular_functionmRNA binding
6g0005515molecular_functionprotein binding
6g0005634cellular_componentnucleus
6g0005654cellular_componentnucleoplasm
6g0005681cellular_componentspliceosomal complex
6g0005688cellular_componentU6 snRNP
6g0006397biological_processmRNA processing
6g0008380biological_processRNA splicing
6g0017070molecular_functionU6 snRNA binding
6g0046540cellular_componentU4/U6 x U5 tri-snRNP complex
6g0071005cellular_componentU2-type precatalytic spliceosome
6g0071011cellular_componentprecatalytic spliceosome
6g0120115cellular_componentLsm2-8 complex
Functional Information from PROSITE/UniProt
site_idPS00039
Number of Residues9
DetailsDEAD_ATP_HELICASE DEAD-box subfamily ATP-dependent helicases signature. VLDEADRmI
ChainResidueDetails
4UVAL547-ILE555

site_idPS00108
Number of Residues13
DetailsPROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. IlHaDIKpdNILV
ChainResidueDetails
4YILE811-VAL823

site_idPS00290
Number of Residues7
DetailsIG_MHC Immunoglobulins and major histocompatibility complex proteins signature. FVCSATH
ChainResidueDetails
2IPHE287-HIS293

site_idPS00436
Number of Residues12
DetailsPEROXIDASE_2 Peroxidases active site signature. TVrvARVmWHPS
ChainResidueDetails
4CTHR323-SER334

site_idPS00678
Number of Residues15
DetailsWD_REPEATS_1 Trp-Asp (WD) repeats signature. LASAgfDrLILLWNV
ChainResidueDetails
5ELEU81-VAL95
5ELEU124-SER138
5EVAL167-ILE181
5EILE208-LEU222
5EILE300-THR314
4CLEU338-LEU352
4CILE422-LEU436

site_idPS01082
Number of Residues18
DetailsRIBOSOMAL_L7AE Ribosomal protein L7Ae signature. CedknVPYvfVrSKqaLG
ChainResidueDetails
4ECYS73-GLY90

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsSITE: Interaction with RNA => ECO:0000269|PubMed:27720643
ChainResidueDetails
2MTYR5
2LCYS72
2LCYS75
2LCYS85
2MGLY20
2LCYS26
2LCYS30
2LCYS33
2LCYS46
2LCYS49
2LCYS58
2LCYS61

site_idSWS_FT_FI2
Number of Residues1
DetailsMOD_RES: N-acetylthreonine => ECO:0007744|PubMed:19413330
ChainResidueDetails
2MTHR2
2ILYS1171
4THIS155
4THIS161

site_idSWS_FT_FI3
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:17525332
ChainResidueDetails
2MSER9
2GCYS677
2GGLU1205
4RARG181

site_idSWS_FT_FI4
Number of Residues1
DetailsMOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861
ChainResidueDetails
2MLYS17
2GTHR235
2GTHR426
4BLYS252
4cLYS8
2cLYS6
2cLYS8

site_idSWS_FT_FI5
Number of Residues1
DetailsMOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861
ChainResidueDetails
2LLYS3
2HSER309
2FSER369

site_idSWS_FT_FI6
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163
ChainResidueDetails
2LSER94
2GLYS554
2GLYS562

site_idSWS_FT_FI7
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163
ChainResidueDetails
2HSER317
2HSER861

site_idSWS_FT_FI8
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:19690332
ChainResidueDetails
2HSER360
2HSER362
4YSER366
4YSER368

site_idSWS_FT_FI9
Number of Residues3
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:18318008, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569
ChainResidueDetails
2HSER431
2HSER435
2HSER436

site_idSWS_FT_FI10
Number of Residues1
DetailsMOD_RES: Symmetric dimethylarginine; by PRMT9; alternate => ECO:0000269|PubMed:25737013
ChainResidueDetails
2HARG508
2DLYS131
2DLYS424
2DLYS499

site_idSWS_FT_FI11
Number of Residues1
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163
ChainResidueDetails
2HTHR780
2DLYS686
4DLYS478

site_idSWS_FT_FI12
Number of Residues9
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733
ChainResidueDetails
2HLYS10
4SLYS648
4SLYS657
4SLYS684
4SLYS699
4SLYS709
4SLYS723
4SLYS749
4SLYS758
4SLYS775
4SLYS780
4SLYS791
2HLYS280
2HLYS492
2HLYS543
2HLYS770
2HLYS790
2HLYS843
2HLYS857

site_idSWS_FT_FI13
Number of Residues1
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:25755297, ECO:0007744|PubMed:25772364, ECO:0007744|PubMed:28112733
ChainResidueDetails
2HLYS400

site_idSWS_FT_FI14
Number of Residues1
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:25218447, ECO:0007744|PubMed:28112733
ChainResidueDetails
2HLYS412
4YSER292

site_idSWS_FT_FI15
Number of Residues1
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:23186163
ChainResidueDetails
2GTHR227
4YSER241
4YSER283
4YSER565

site_idSWS_FT_FI16
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q99NB9
ChainResidueDetails
2GSER229

site_idSWS_FT_FI17
Number of Residues1
DetailsMOD_RES: Phosphothreonine => ECO:0000269|PubMed:12105215
ChainResidueDetails
2GTHR244

site_idSWS_FT_FI18
Number of Residues1
DetailsMOD_RES: Phosphothreonine => ECO:0000305|PubMed:12105215
ChainResidueDetails
2GTHR248

site_idSWS_FT_FI19
Number of Residues5
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569
ChainResidueDetails
2GTHR257
2GTHR261
2GTHR278
2GTHR303
2GTHR313

site_idSWS_FT_FI20
Number of Residues1
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:18220336, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569
ChainResidueDetails
2GTHR267

site_idSWS_FT_FI21
Number of Residues1
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:24275569
ChainResidueDetails
2GTHR273
4YSER437

site_idSWS_FT_FI22
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:24275569
ChainResidueDetails
2GSER287

site_idSWS_FT_FI23
Number of Residues1
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:23186163
ChainResidueDetails
2GTHR296

site_idSWS_FT_FI24
Number of Residues1
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:17081983
ChainResidueDetails
2GTHR299
4YSER520

site_idSWS_FT_FI25
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163
ChainResidueDetails
2GSER322

site_idSWS_FT_FI26
Number of Residues1
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163
ChainResidueDetails
2GTHR326
4YSER580

site_idSWS_FT_FI27
Number of Residues1
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:16964243, ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231
ChainResidueDetails
2GTHR328

site_idSWS_FT_FI28
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:23186163
ChainResidueDetails
2GSER332

site_idSWS_FT_FI29
Number of Residues1
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:21406692
ChainResidueDetails
2GTHR341

site_idSWS_FT_FI30
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:21406692
ChainResidueDetails
2GSER344
4YLYS111
4YLYS177
4YLYS593
4YLYS659

site_idSWS_FT_FI31
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:21406692
ChainResidueDetails
2GSER349

site_idSWS_FT_FI32
Number of Residues2
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:23186163
ChainResidueDetails
2GTHR350
2GTHR436

site_idSWS_FT_FI33
Number of Residues1
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:18691976, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163
ChainResidueDetails
2GTHR354

site_idSWS_FT_FI34
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:23186163
ChainResidueDetails
2GSER400

site_idSWS_FT_FI35
Number of Residues1
DetailsMOD_RES: Phosphothreonine; by DYRK1A => ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:23186163
ChainResidueDetails
2GTHR434

site_idSWS_FT_FI36
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569
ChainResidueDetails
2GSER488

site_idSWS_FT_FI37
Number of Residues1
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744|PubMed:28112733
ChainResidueDetails
2GLYS214

site_idSWS_FT_FI38
Number of Residues2
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733
ChainResidueDetails
2GLYS430

site_idSWS_FT_FI39
Number of Residues1
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744|PubMed:25114211, ECO:0007744|PubMed:25218447, ECO:0007744|PubMed:25755297, ECO:0007744|PubMed:28112733
ChainResidueDetails
2GLYS413

226707

PDB entries from 2024-10-30

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