8H59

A fungal MAP kinase in complex with an inhibitor

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000165	biological_process	MAPK cascade
A	0004672	molecular_function	protein kinase activity
A	0004707	molecular_function	MAP kinase activity
A	0005524	molecular_function	ATP binding
A	0006468	biological_process	protein phosphorylation
A	0006950	biological_process	response to stress
A	0051094	biological_process	positive regulation of developmental process
A	0106310	molecular_function	protein serine kinase activity

Functional Information from PROSITE/UniProt

site_id	PS00107
Number of Residues	25
Details	PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGQGAYGIVCaAvnnqtsegv.........AIKK

Chain	Residue	Details
A	LEU29-LYS53

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site_id	PS00108
Number of Residues	13
Details	PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. VlHrDLKpgNLLV

Chain	Residue	Details
A	VAL145-VAL157

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site_id	PS01351
Number of Residues	104
Details	MAPK MAP kinase signature. FskkilakralREikllqhfrghrnitclydmdiprpdnfnetylyeelmecdlaaiirsgqpltdahfqsfiyqilcglkyihsanvlh.........RDlKpgnllvnadC

Chain	Residue	Details
A	PHE58-CYS161

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	291
Details	Domain: {"description":"Protein kinase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	9
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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