8GZ4

Crystal structure of MPXV phosphatase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004721	molecular_function	phosphoprotein phosphatase activity
A	0006470	biological_process	protein dephosphorylation
A	0008330	molecular_function	protein tyrosine/threonine phosphatase activity
A	0016311	biological_process	dephosphorylation
A	0017017	molecular_function	MAP kinase tyrosine/serine/threonine phosphatase activity
A	0019049	biological_process	virus-mediated perturbation of host defense response
A	0030430	cellular_component	host cell cytoplasm
A	0033550	molecular_function	MAP kinase tyrosine phosphatase activity
A	0039502	biological_process	symbiont-mediated suppression of host type I interferon-mediated signaling pathway
A	0039563	biological_process	symbiont-mediated suppression of host JAK-STAT cascade via inhibition of STAT1 activity
A	0043409	biological_process	negative regulation of MAPK cascade
A	0044423	cellular_component	virion component
A	0052170	biological_process	symbiont-mediated suppression of host innate immune response

Functional Information from PROSITE/UniProt

site_id	PS00383
Number of Residues	11
Details	TYR_PHOSPHATASE_1 Tyrosine specific protein phosphatases active site. VHCvaGvnRSG

Chain	Residue	Details
A	VAL108-GLY118

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