8GRV

Dictyostelium discoideum Lactate dehydrogenase (DicLDHA)with NAD

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008720	molecular_function	D-lactate dehydrogenase activity
A	0016491	molecular_function	oxidoreductase activity
A	0016616	molecular_function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
A	0045335	cellular_component	phagocytic vesicle
A	0051287	molecular_function	NAD binding

Functional Information from PROSITE/UniProt

site_id	PS00670
Number of Residues	23
Details	D_2_HYDROXYACID_DH_2 D-isomer specific 2-hydroxyacid dehydrogenases signature 2. IWkqCDVIsLHtPlnsqTkyMvN

Chain	Residue	Details
A	ILE195-ASN217

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site_id	PS00671
Number of Residues	17
Details	D_2_HYDROXYACID_DH_3 D-isomer specific 2-hydroxyacid dehydrogenases signature 3. MRdGvMIINvSRGaLVN

Chain	Residue	Details
A	MET224-ASN240

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: ACT_SITE => ECO:0000250|UniProtKB:P26297

Chain	Residue	Details
A	ARG235
A	GLU264

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site_id	SWS_FT_FI2
Number of Residues	1
Details	ACT_SITE: Proton donor => ECO:0000250|UniProtKB:P26297

Chain	Residue	Details
A	HIS296

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site_id	SWS_FT_FI3
Number of Residues	4
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P30901

Chain	Residue	Details
A	ASN153
A	THR206
A	VAL233
A	ASP259

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site_id	SWS_FT_FI4
Number of Residues	1
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P26297

Chain	Residue	Details
A	ASP174

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