8GQH

Structure of Thiolase from Pseudomonas aeruginosa PAO1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003988	molecular_function	acetyl-CoA C-acyltransferase activity
A	0006635	biological_process	fatty acid beta-oxidation
A	0010124	biological_process	phenylacetate catabolic process
A	0016746	molecular_function	acyltransferase activity
A	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
A	0019439	biological_process	obsolete aromatic compound catabolic process
A	0033812	molecular_function	3-oxoadipyl-CoA thiolase activity
A	0042952	biological_process	beta-ketoadipate pathway
B	0003988	molecular_function	acetyl-CoA C-acyltransferase activity
B	0006635	biological_process	fatty acid beta-oxidation
B	0010124	biological_process	phenylacetate catabolic process
B	0016746	molecular_function	acyltransferase activity
B	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
B	0019439	biological_process	obsolete aromatic compound catabolic process
B	0033812	molecular_function	3-oxoadipyl-CoA thiolase activity
B	0042952	biological_process	beta-ketoadipate pathway
C	0003988	molecular_function	acetyl-CoA C-acyltransferase activity
C	0006635	biological_process	fatty acid beta-oxidation
C	0010124	biological_process	phenylacetate catabolic process
C	0016746	molecular_function	acyltransferase activity
C	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
C	0019439	biological_process	obsolete aromatic compound catabolic process
C	0033812	molecular_function	3-oxoadipyl-CoA thiolase activity
C	0042952	biological_process	beta-ketoadipate pathway
D	0003988	molecular_function	acetyl-CoA C-acyltransferase activity
D	0006635	biological_process	fatty acid beta-oxidation
D	0010124	biological_process	phenylacetate catabolic process
D	0016746	molecular_function	acyltransferase activity
D	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
D	0019439	biological_process	obsolete aromatic compound catabolic process
D	0033812	molecular_function	3-oxoadipyl-CoA thiolase activity
D	0042952	biological_process	beta-ketoadipate pathway

Functional Information from PROSITE/UniProt

site_id	PS00098
Number of Residues	19
Details	THIOLASE_1 Thiolases acyl-enzyme intermediate signature. LNRlCASGMdAIgtafraI

Chain	Residue	Details
A	LEU87-ILE105

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site_id	PS00099
Number of Residues	14
Details	THIOLASE_3 Thiolases active site. GLATMCVGvGqGlA

Chain	Residue	Details
A	GLY382-ALA395

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site_id	PS00737
Number of Residues	17
Details	THIOLASE_2 Thiolases signature 2. NpnGGaIAlGHPlGmSG

Chain	Residue	Details
A	ASN347-GLY363

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: Acyl-thioester intermediate => ECO:0000250

Chain	Residue	Details
A	CYS91
B	CYS91
C	CYS91
D	CYS91

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site_id	SWS_FT_FI2
Number of Residues	8
Details	ACT_SITE: Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU10020

Chain	Residue	Details
A	HIS357
A	CYS387
B	HIS357
B	CYS387
C	HIS357
C	CYS387
D	HIS357
D	CYS387

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