8GQH

Structure of Thiolase from Pseudomonas aeruginosa PAO1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003988	molecular_function	acetyl-CoA C-acyltransferase activity
A	0006629	biological_process	lipid metabolic process
A	0006635	biological_process	fatty acid beta-oxidation
A	0010124	biological_process	phenylacetate catabolic process
A	0016746	molecular_function	acyltransferase activity
A	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
A	0019619	biological_process	3,4-dihydroxybenzoate catabolic process
A	0033812	molecular_function	3-oxoadipyl-CoA thiolase activity
A	0042952	biological_process	beta-ketoadipate pathway
B	0003988	molecular_function	acetyl-CoA C-acyltransferase activity
B	0006629	biological_process	lipid metabolic process
B	0006635	biological_process	fatty acid beta-oxidation
B	0010124	biological_process	phenylacetate catabolic process
B	0016746	molecular_function	acyltransferase activity
B	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
B	0019619	biological_process	3,4-dihydroxybenzoate catabolic process
B	0033812	molecular_function	3-oxoadipyl-CoA thiolase activity
B	0042952	biological_process	beta-ketoadipate pathway
C	0003988	molecular_function	acetyl-CoA C-acyltransferase activity
C	0006629	biological_process	lipid metabolic process
C	0006635	biological_process	fatty acid beta-oxidation
C	0010124	biological_process	phenylacetate catabolic process
C	0016746	molecular_function	acyltransferase activity
C	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
C	0019619	biological_process	3,4-dihydroxybenzoate catabolic process
C	0033812	molecular_function	3-oxoadipyl-CoA thiolase activity
C	0042952	biological_process	beta-ketoadipate pathway
D	0003988	molecular_function	acetyl-CoA C-acyltransferase activity
D	0006629	biological_process	lipid metabolic process
D	0006635	biological_process	fatty acid beta-oxidation
D	0010124	biological_process	phenylacetate catabolic process
D	0016746	molecular_function	acyltransferase activity
D	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
D	0019619	biological_process	3,4-dihydroxybenzoate catabolic process
D	0033812	molecular_function	3-oxoadipyl-CoA thiolase activity
D	0042952	biological_process	beta-ketoadipate pathway

Functional Information from PROSITE/UniProt

site_id	PS00098
Number of Residues	19
Details	THIOLASE_1 Thiolases acyl-enzyme intermediate signature. LNRlCASGMdAIgtafraI

Chain	Residue	Details
A	LEU87-ILE105

---

site_id	PS00099
Number of Residues	14
Details	THIOLASE_3 Thiolases active site. GLATMCVGvGqGlA

Chain	Residue	Details
A	GLY382-ALA395

---

site_id	PS00737
Number of Residues	17
Details	THIOLASE_2 Thiolases signature 2. NpnGGaIAlGHPlGmSG

Chain	Residue	Details
A	ASN347-GLY363

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Active site: {"description":"Acyl-thioester intermediate","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	8
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU10020","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---