8GQG

Crystal structure of Thioloase from Pseudomonas aeruginosa PAO1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003988	molecular_function	acetyl-CoA C-acyltransferase activity
A	0005737	cellular_component	cytoplasm
A	0006629	biological_process	lipid metabolic process
A	0006631	biological_process	fatty acid metabolic process
A	0006635	biological_process	fatty acid beta-oxidation
A	0010124	biological_process	phenylacetate catabolic process
A	0016740	molecular_function	transferase activity
A	0016746	molecular_function	acyltransferase activity
A	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
A	0033812	molecular_function	3-oxoadipyl-CoA thiolase activity
A	0044281	biological_process	small molecule metabolic process
B	0003988	molecular_function	acetyl-CoA C-acyltransferase activity
B	0005737	cellular_component	cytoplasm
B	0006629	biological_process	lipid metabolic process
B	0006631	biological_process	fatty acid metabolic process
B	0006635	biological_process	fatty acid beta-oxidation
B	0010124	biological_process	phenylacetate catabolic process
B	0016740	molecular_function	transferase activity
B	0016746	molecular_function	acyltransferase activity
B	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
B	0033812	molecular_function	3-oxoadipyl-CoA thiolase activity
B	0044281	biological_process	small molecule metabolic process
C	0003988	molecular_function	acetyl-CoA C-acyltransferase activity
C	0005737	cellular_component	cytoplasm
C	0006629	biological_process	lipid metabolic process
C	0006631	biological_process	fatty acid metabolic process
C	0006635	biological_process	fatty acid beta-oxidation
C	0010124	biological_process	phenylacetate catabolic process
C	0016740	molecular_function	transferase activity
C	0016746	molecular_function	acyltransferase activity
C	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
C	0033812	molecular_function	3-oxoadipyl-CoA thiolase activity
C	0044281	biological_process	small molecule metabolic process
D	0003988	molecular_function	acetyl-CoA C-acyltransferase activity
D	0005737	cellular_component	cytoplasm
D	0006629	biological_process	lipid metabolic process
D	0006631	biological_process	fatty acid metabolic process
D	0006635	biological_process	fatty acid beta-oxidation
D	0010124	biological_process	phenylacetate catabolic process
D	0016740	molecular_function	transferase activity
D	0016746	molecular_function	acyltransferase activity
D	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
D	0033812	molecular_function	3-oxoadipyl-CoA thiolase activity
D	0044281	biological_process	small molecule metabolic process
E	0003988	molecular_function	acetyl-CoA C-acyltransferase activity
E	0005737	cellular_component	cytoplasm
E	0006629	biological_process	lipid metabolic process
E	0006631	biological_process	fatty acid metabolic process
E	0006635	biological_process	fatty acid beta-oxidation
E	0010124	biological_process	phenylacetate catabolic process
E	0016740	molecular_function	transferase activity
E	0016746	molecular_function	acyltransferase activity
E	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
E	0033812	molecular_function	3-oxoadipyl-CoA thiolase activity
E	0044281	biological_process	small molecule metabolic process
F	0003988	molecular_function	acetyl-CoA C-acyltransferase activity
F	0005737	cellular_component	cytoplasm
F	0006629	biological_process	lipid metabolic process
F	0006631	biological_process	fatty acid metabolic process
F	0006635	biological_process	fatty acid beta-oxidation
F	0010124	biological_process	phenylacetate catabolic process
F	0016740	molecular_function	transferase activity
F	0016746	molecular_function	acyltransferase activity
F	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
F	0033812	molecular_function	3-oxoadipyl-CoA thiolase activity
F	0044281	biological_process	small molecule metabolic process

Functional Information from PROSITE/UniProt

site_id	PS00098
Number of Residues	19
Details	THIOLASE_1 Thiolases acyl-enzyme intermediate signature. LNRyCSSGLqAIaiaanqI

Chain	Residue	Details
A	LEU86-ILE104

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site_id	PS00099
Number of Residues	14
Details	THIOLASE_3 Thiolases active site. GVVTMCVGgGmGaS

Chain	Residue	Details
A	GLY374-SER387

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site_id	PS00737
Number of Residues	17
Details	THIOLASE_2 Thiolases signature 2. NvnGGsIAiGHPfGmTG

Chain	Residue	Details
A	ASN339-GLY355

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