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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

8GJ0

E. coli clamp loader with open clamp on primed template DNA (form 1)

Functional Information from GO Data
ChainGOidnamespacecontents
A0003677molecular_functionDNA binding
A0003689molecular_functionDNA clamp loader activity
A0003887molecular_functionDNA-directed DNA polymerase activity
A0005515molecular_functionprotein binding
A0006260biological_processDNA replication
A0006261biological_processDNA-templated DNA replication
A0009360cellular_componentDNA polymerase III complex
A0016740molecular_functiontransferase activity
A0016779molecular_functionnucleotidyltransferase activity
A0034061molecular_functionDNA polymerase activity
A0071897biological_processDNA biosynthetic process
B0000166molecular_functionnucleotide binding
B0003677molecular_functionDNA binding
B0003887molecular_functionDNA-directed DNA polymerase activity
B0005515molecular_functionprotein binding
B0005524molecular_functionATP binding
B0006260biological_processDNA replication
B0006261biological_processDNA-templated DNA replication
B0009360cellular_componentDNA polymerase III complex
B0016740molecular_functiontransferase activity
B0016779molecular_functionnucleotidyltransferase activity
B0034061molecular_functionDNA polymerase activity
B0042802molecular_functionidentical protein binding
B0046872molecular_functionmetal ion binding
B0071897biological_processDNA biosynthetic process
B0075523biological_processviral translational frameshifting
C0000166molecular_functionnucleotide binding
C0003677molecular_functionDNA binding
C0003887molecular_functionDNA-directed DNA polymerase activity
C0005515molecular_functionprotein binding
C0005524molecular_functionATP binding
C0006260biological_processDNA replication
C0006261biological_processDNA-templated DNA replication
C0009360cellular_componentDNA polymerase III complex
C0016740molecular_functiontransferase activity
C0016779molecular_functionnucleotidyltransferase activity
C0034061molecular_functionDNA polymerase activity
C0042802molecular_functionidentical protein binding
C0046872molecular_functionmetal ion binding
C0071897biological_processDNA biosynthetic process
C0075523biological_processviral translational frameshifting
D0000166molecular_functionnucleotide binding
D0003677molecular_functionDNA binding
D0003887molecular_functionDNA-directed DNA polymerase activity
D0005515molecular_functionprotein binding
D0005524molecular_functionATP binding
D0006260biological_processDNA replication
D0006261biological_processDNA-templated DNA replication
D0009360cellular_componentDNA polymerase III complex
D0016740molecular_functiontransferase activity
D0016779molecular_functionnucleotidyltransferase activity
D0034061molecular_functionDNA polymerase activity
D0042802molecular_functionidentical protein binding
D0046872molecular_functionmetal ion binding
D0071897biological_processDNA biosynthetic process
D0075523biological_processviral translational frameshifting
E0003677molecular_functionDNA binding
E0003689molecular_functionDNA clamp loader activity
E0003887molecular_functionDNA-directed DNA polymerase activity
E0005515molecular_functionprotein binding
E0006260biological_processDNA replication
E0006261biological_processDNA-templated DNA replication
E0008408molecular_function3'-5' exonuclease activity
E0009360cellular_componentDNA polymerase III complex
E0016740molecular_functiontransferase activity
E0016779molecular_functionnucleotidyltransferase activity
E0034061molecular_functionDNA polymerase activity
E0071897biological_processDNA biosynthetic process
F0003887molecular_functionDNA-directed DNA polymerase activity
F0005515molecular_functionprotein binding
F0006260biological_processDNA replication
F0006261biological_processDNA-templated DNA replication
F0008408molecular_function3'-5' exonuclease activity
F0009314biological_processresponse to radiation
F0016740molecular_functiontransferase activity
F0016779molecular_functionnucleotidyltransferase activity
F0034061molecular_functionDNA polymerase activity
F0071897biological_processDNA biosynthetic process
H0003677molecular_functionDNA binding
H0003887molecular_functionDNA-directed DNA polymerase activity
H0005515molecular_functionprotein binding
H0005737cellular_componentcytoplasm
H0005829cellular_componentcytosol
H0006260biological_processDNA replication
H0006261biological_processDNA-templated DNA replication
H0006271biological_processDNA strand elongation involved in DNA replication
H0006974biological_processDNA damage response
H0008408molecular_function3'-5' exonuclease activity
H0009360cellular_componentDNA polymerase III complex
H0016740molecular_functiontransferase activity
H0016779molecular_functionnucleotidyltransferase activity
H0030174biological_processregulation of DNA-templated DNA replication initiation
H0032297biological_processnegative regulation of DNA-templated DNA replication initiation
H0042276biological_processerror-prone translesion synthesis
H0042802molecular_functionidentical protein binding
H0042803molecular_functionprotein homodimerization activity
H0044787biological_processbacterial-type DNA replication
I0003677molecular_functionDNA binding
I0003887molecular_functionDNA-directed DNA polymerase activity
I0005515molecular_functionprotein binding
I0005737cellular_componentcytoplasm
I0005829cellular_componentcytosol
I0006260biological_processDNA replication
I0006261biological_processDNA-templated DNA replication
I0006271biological_processDNA strand elongation involved in DNA replication
I0006974biological_processDNA damage response
I0008408molecular_function3'-5' exonuclease activity
I0009360cellular_componentDNA polymerase III complex
I0016740molecular_functiontransferase activity
I0016779molecular_functionnucleotidyltransferase activity
I0030174biological_processregulation of DNA-templated DNA replication initiation
I0032297biological_processnegative regulation of DNA-templated DNA replication initiation
I0042276biological_processerror-prone translesion synthesis
I0042802molecular_functionidentical protein binding
I0042803molecular_functionprotein homodimerization activity
I0044787biological_processbacterial-type DNA replication
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues139
DetailsRegion: {"description":"Domain 1","evidences":[{"source":"PubMed","id":"11525728","evidenceCode":"ECO:0000305"}]}
ChainResidueDetails
site_idSWS_FT_FI2
Number of Residues69
DetailsRegion: {"description":"Domain 2","evidences":[{"source":"PubMed","id":"11525728","evidenceCode":"ECO:0000305"}]}
ChainResidueDetails
site_idSWS_FT_FI3
Number of Residues132
DetailsRegion: {"description":"Domain 3","evidences":[{"source":"PubMed","id":"11525728","evidenceCode":"ECO:0000305"}]}
ChainResidueDetails
site_idSWS_FT_FI4
Number of Residues21
DetailsBinding site: {"evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI5
Number of Residues12
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"11525729","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1JR3","evidenceCode":"ECO:0007744"}]}
ChainResidueDetails
site_idSWS_FT_FI6
Number of Residues238
DetailsRegion: {"description":"1","evidences":[{"evidenceCode":"ECO:0000305"}]}
ChainResidueDetails
site_idSWS_FT_FI7
Number of Residues228
DetailsRegion: {"description":"2","evidences":[{"evidenceCode":"ECO:0000305"}]}
ChainResidueDetails
site_idSWS_FT_FI8
Number of Residues240
DetailsRegion: {"description":"3","evidences":[{"evidenceCode":"ECO:0000305"}]}
ChainResidueDetails
site_idSWS_FT_FI9
Number of Residues6
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"18191219","evidenceCode":"ECO:0000305"}]}
ChainResidueDetails
site_idSWS_FT_FI10
Number of Residues2
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"18191219","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

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PDB entries from 2025-12-31

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