8GE0
Crystal structure of JADE1 PZP domain in complex with Histone H3
Functional Information from PROSITE/UniProt
| site_id | PS01359 |
| Number of Residues | 45 |
| Details | ZF_PHD_1 Zinc finger PHD-type signature. CdvCqspdgedgnem..................................VfCdk..Cnic.VHqaCygilkvpegs...................................WlCrtC |
| Chain | Residue | Details |
| A | CYS23-CYS67 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | MOD_RES: Citrulline; alternate => ECO:0000269|PubMed:16567635 |
| Chain | Residue | Details |
| A | ARG2 | |
| B | ARG2 | |
| C | ARG2 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | MOD_RES: Phosphothreonine; by HASPIN and VRK1 => ECO:0000269|PubMed:15681610, ECO:0000269|PubMed:16185088, ECO:0000269|PubMed:31527692 |
| Chain | Residue | Details |
| A | THR3 | |
| B | THR3 | |
| C | THR3 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | MOD_RES: N6-methyllysine; alternate => ECO:0000269|PubMed:16267050, ECO:0000269|PubMed:16457588, ECO:0000269|PubMed:17194708 |
| Chain | Residue | Details |
| A | LYS4 | |
| B | LYS4 | |
| C | LYS4 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | MOD_RES: 5-glutamyl serotonin; alternate => ECO:0000269|PubMed:30867594 |
| Chain | Residue | Details |
| A | GLN5 | |
| B | GLN5 | |
| C | GLN5 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 3 |
| Details | MOD_RES: Phosphothreonine; by PKC => ECO:0000269|PubMed:20228790 |
| Chain | Residue | Details |
| A | THR6 | |
| B | THR6 | |
| C | THR6 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 3 |
| Details | MOD_RES: Symmetric dimethylarginine; by PRMT5; alternate => ECO:0000250|UniProtKB:P68433 |
| Chain | Residue | Details |
| A | ARG8 | |
| B | ARG8 | |
| C | ARG8 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 3 |
| Details | MOD_RES: N6-methyllysine; alternate => ECO:0000269|PubMed:11242053, ECO:0000269|PubMed:16185088, ECO:0000269|PubMed:16267050, ECO:0000269|PubMed:16457588, ECO:0000269|PubMed:17194708 |
| Chain | Residue | Details |
| A | LYS9 | |
| B | LYS9 | |
| C | LYS9 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 3 |
| Details | MOD_RES: Phosphoserine; alternate; by AURKB, AURKC, RPS6KA3, RPS6KA4 and RPS6KA5 => ECO:0000269|PubMed:10464286, ECO:0000269|PubMed:11856369, ECO:0000269|PubMed:12560483, ECO:0000269|PubMed:15681610, ECO:0000269|PubMed:16185088, ECO:0000269|PubMed:16457588 |
| Chain | Residue | Details |
| A | SER10 | |
| B | SER10 | |
| C | SER10 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 3 |
| Details | MOD_RES: Phosphothreonine; by PKC and CHEK1 => ECO:0000269|PubMed:12560483, ECO:0000269|PubMed:18066052, ECO:0000269|PubMed:18243098, ECO:0000269|PubMed:22901803 |
| Chain | Residue | Details |
| A | THR11 | |
| B | THR11 | |
| C | THR11 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 150 |
| Details | ZN_FING: PHD-type 1 => ECO:0000255|PROSITE-ProRule:PRU00146 |
| Chain | Residue | Details |
| A | ASP20-GLY70 | |
| B | ASP20-GLY70 | |
| C | ASP20-GLY70 |
| site_id | SWS_FT_FI11 |
| Number of Residues | 102 |
| Details | ZN_FING: C2HC pre-PHD-type => ECO:0000255|PROSITE-ProRule:PRU01146 |
| Chain | Residue | Details |
| A | GLN72-VAL106 | |
| B | GLN72-VAL106 | |
| C | GLN72-VAL106 |
| site_id | SWS_FT_FI12 |
| Number of Residues | 168 |
| Details | ZN_FING: PHD-type 2 => ECO:0000255|PROSITE-ProRule:PRU01146 |
| Chain | Residue | Details |
| A | LEU130-SER186 | |
| B | LEU130-SER186 | |
| C | LEU130-SER186 |
