Functional Information from GO Data
| Chain | GOid | namespace | contents |
| F | 0004252 | molecular_function | serine-type endopeptidase activity |
| F | 0006508 | biological_process | proteolysis |
| G | 0004252 | molecular_function | serine-type endopeptidase activity |
| G | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 G 297 |
| Chain | Residue |
| F | ASN18 |
| G | THR222 |
| G | HOH395 |
| G | HOH440 |
| G | HOH521 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 F 298 |
| Chain | Residue |
| F | GLN116 |
| F | HOH464 |
| F | HOH476 |
| F | SER115 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 G 299 |
| Chain | Residue |
| G | PRO152 |
| G | ASP153 |
| G | ARG154 |
| G | HOH452 |
| G | HOH554 |
| G | HOH594 |
| G | HOH637 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 F 300 |
| Chain | Residue |
| F | LYS36 |
| F | SER92 |
| F | HOH302 |
| F | HOH335 |
| F | HOH567 |
| G | TRP237 |
| site_id | AC5 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR CHAIN C OF GLY ALA TRP PEPTIDE |
| Chain | Residue |
| C | HOH486 |
| C | HOH487 |
| C | HOH530 |
| C | HOH617 |
| C | HOH647 |
| F | HIS57 |
| F | HOH615 |
| G | SER189 |
| G | SER190 |
| G | CYS191 |
| G | MET192 |
| G | GLY193 |
| G | ASP194 |
| G | SER195 |
| G | SER214 |
| G | TRP215 |
| G | GLY216 |
| G | SER217 |
| G | GLY226 |
| G | HOH551 |
| site_id | CAT |
| Number of Residues | 3 |
| Details | catalytic site |
| Chain | Residue |
| F | HIS57 |
| F | ASP102 |
| G | SER195 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VTAAHC |
| Chain | Residue | Details |
| F | VAL53-CYS58 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. SScmGDSGGPLV |
| Chain | Residue | Details |
| G | SER189-VAL200 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Charge relay system |
| Chain | Residue | Details |
| F | HIS57 | |
| F | ASP102 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1hja |
| Chain | Residue | Details |
| G | SER195 | |
| G | GLY193 | |
| site_id | CSA2 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1hja |
| Chain | Residue | Details |
| F | ASP102 | |
| F | HIS57 | |
| G | SER195 | |
| G | GLY196 | |
| site_id | MCSA1 |
| Number of Residues | 2 |
| Details | M-CSA 387 |
| Chain | Residue | Details |
| F | HIS57 | electrostatic stabiliser, proton shuttle (general acid/base) |
| F | ASP102 | modifies pKa |
| G | GLY196 | electrostatic stabiliser |
