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8G7S

Structure of the Escherichia coli 70S ribosome in complex with P-site tRNAIle(LAU) bound to the cognate AUA codon (Structure IV)

This is a non-PDB format compatible entry.
Functional Information from GO Data
ChainGOidnamespacecontents
10003735molecular_functionstructural constituent of ribosome
10005840cellular_componentribosome
10006412biological_processtranslation
20003735molecular_functionstructural constituent of ribosome
20006412biological_processtranslation
20015934cellular_componentlarge ribosomal subunit
30002181biological_processcytoplasmic translation
30003735molecular_functionstructural constituent of ribosome
30005737cellular_componentcytoplasm
30005829cellular_componentcytosol
30005840cellular_componentribosome
30006412biological_processtranslation
30006413biological_processtranslational initiation
30008270molecular_functionzinc ion binding
30019843molecular_functionrRNA binding
30022625cellular_componentcytosolic large ribosomal subunit
30046872molecular_functionmetal ion binding
31904689biological_processnegative regulation of cytoplasmic translational initiation
31990904cellular_componentribonucleoprotein complex
40003735molecular_functionstructural constituent of ribosome
40006412biological_processtranslation
40015934cellular_componentlarge ribosomal subunit
50003735molecular_functionstructural constituent of ribosome
50005840cellular_componentribosome
50006412biological_processtranslation
60003735molecular_functionstructural constituent of ribosome
60005840cellular_componentribosome
60006412biological_processtranslation
61990904cellular_componentribonucleoprotein complex
70002181biological_processcytoplasmic translation
70003735molecular_functionstructural constituent of ribosome
70005737cellular_componentcytoplasm
70005840cellular_componentribosome
70006412biological_processtranslation
70022625cellular_componentcytosolic large ribosomal subunit
71990904cellular_componentribonucleoprotein complex
80003735molecular_functionstructural constituent of ribosome
80005737cellular_componentcytoplasm
80005840cellular_componentribosome
80006412biological_processtranslation
81990904cellular_componentribonucleoprotein complex
C0000027biological_processribosomal large subunit assembly
C0002181biological_processcytoplasmic translation
C0003723molecular_functionRNA binding
C0003735molecular_functionstructural constituent of ribosome
C0005515molecular_functionprotein binding
C0005737cellular_componentcytoplasm
C0005829cellular_componentcytosol
C0005840cellular_componentribosome
C0006412biological_processtranslation
C0008270molecular_functionzinc ion binding
C0015934cellular_componentlarge ribosomal subunit
C0016740molecular_functiontransferase activity
C0019843molecular_functionrRNA binding
C0022625cellular_componentcytosolic large ribosomal subunit
C0032297biological_processnegative regulation of DNA-templated DNA replication initiation
C1990082cellular_componentDnaA-L2 complex
C1990904cellular_componentribonucleoprotein complex
D0003735molecular_functionstructural constituent of ribosome
D0005840cellular_componentribosome
D0006412biological_processtranslation
E0003735molecular_functionstructural constituent of ribosome
E0005840cellular_componentribosome
E0006412biological_processtranslation
E0019843molecular_functionrRNA binding
E1990904cellular_componentribonucleoprotein complex
F0003735molecular_functionstructural constituent of ribosome
F0005840cellular_componentribosome
F0006412biological_processtranslation
G0002181biological_processcytoplasmic translation
G0003735molecular_functionstructural constituent of ribosome
G0005840cellular_componentribosome
G0006412biological_processtranslation
G0019843molecular_functionrRNA binding
G0022625cellular_componentcytosolic large ribosomal subunit
G1990904cellular_componentribonucleoprotein complex
H0003735molecular_functionstructural constituent of ribosome
H0005840cellular_componentribosome
H0006412biological_processtranslation
L0003735molecular_functionstructural constituent of ribosome
L0005840cellular_componentribosome
L0006412biological_processtranslation
M0003735molecular_functionstructural constituent of ribosome
M0005840cellular_componentribosome
M0006412biological_processtranslation
M0015934cellular_componentlarge ribosomal subunit
M0019843molecular_functionrRNA binding
M0022625cellular_componentcytosolic large ribosomal subunit
M0070180molecular_functionlarge ribosomal subunit rRNA binding
M1990904cellular_componentribonucleoprotein complex
N0003735molecular_functionstructural constituent of ribosome
N0005840cellular_componentribosome
N0006412biological_processtranslation
N0015934cellular_componentlarge ribosomal subunit
O0003735molecular_functionstructural constituent of ribosome
O0005840cellular_componentribosome
O0006412biological_processtranslation
O0019843molecular_functionrRNA binding
P0003735molecular_functionstructural constituent of ribosome
P0005840cellular_componentribosome
P0006412biological_processtranslation
Q0003735molecular_functionstructural constituent of ribosome
Q0005840cellular_componentribosome
Q0006412biological_processtranslation
R0003735molecular_functionstructural constituent of ribosome
R0005840cellular_componentribosome
R0006412biological_processtranslation
S0000027biological_processribosomal large subunit assembly
S0003735molecular_functionstructural constituent of ribosome
S0005840cellular_componentribosome
S0006412biological_processtranslation
S0019843molecular_functionrRNA binding
S0022625cellular_componentcytosolic large ribosomal subunit
S1990904cellular_componentribonucleoprotein complex
T0003723molecular_functionRNA binding
T0003735molecular_functionstructural constituent of ribosome
T0005840cellular_componentribosome
T0006412biological_processtranslation
U0002181biological_processcytoplasmic translation
U0003735molecular_functionstructural constituent of ribosome
U0005515molecular_functionprotein binding
U0005737cellular_componentcytoplasm
U0005829cellular_componentcytosol
U0005840cellular_componentribosome
U0006412biological_processtranslation
U0015934cellular_componentlarge ribosomal subunit
U0019843molecular_functionrRNA binding
U0022625cellular_componentcytosolic large ribosomal subunit
U0042255biological_processribosome assembly
U0042256biological_processcytosolic ribosome assembly
U0046677biological_processresponse to antibiotic
U0070180molecular_functionlarge ribosomal subunit rRNA binding
U1902626biological_processassembly of large subunit precursor of preribosome
U1990904cellular_componentribonucleoprotein complex
V0003735molecular_functionstructural constituent of ribosome
V0005840cellular_componentribosome
V0006412biological_processtranslation
V0019843molecular_functionrRNA binding
W0003723molecular_functionRNA binding
W0003735molecular_functionstructural constituent of ribosome
W0005840cellular_componentribosome
W0006412biological_processtranslation
X0003735molecular_functionstructural constituent of ribosome
X0005840cellular_componentribosome
X0006412biological_processtranslation
X0008097molecular_function5S rRNA binding
Y0000027biological_processribosomal large subunit assembly
Y0000049molecular_functiontRNA binding
Y0001558biological_processregulation of cell growth
Y0002181biological_processcytoplasmic translation
Y0003735molecular_functionstructural constituent of ribosome
Y0005515molecular_functionprotein binding
Y0005737cellular_componentcytoplasm
Y0005840cellular_componentribosome
Y0006412biological_processtranslation
Y0019843molecular_functionrRNA binding
Y0022625cellular_componentcytosolic large ribosomal subunit
Y0042256biological_processcytosolic ribosome assembly
Y0043022molecular_functionribosome binding
Y0090070biological_processpositive regulation of ribosome biogenesis
Y1902626biological_processassembly of large subunit precursor of preribosome
Y1990904cellular_componentribonucleoprotein complex
Z0003735molecular_functionstructural constituent of ribosome
Z0005840cellular_componentribosome
Z0006412biological_processtranslation
Z0022625cellular_componentcytosolic large ribosomal subunit
Z1990904cellular_componentribonucleoprotein complex
b0000028biological_processribosomal small subunit assembly
b0003735molecular_functionstructural constituent of ribosome
b0005840cellular_componentribosome
b0006412biological_processtranslation
b0015935cellular_componentsmall ribosomal subunit
b0022627cellular_componentcytosolic small ribosomal subunit
b1990904cellular_componentribonucleoprotein complex
c0003676molecular_functionnucleic acid binding
c0003723molecular_functionRNA binding
c0003729molecular_functionmRNA binding
c0003735molecular_functionstructural constituent of ribosome
c0005840cellular_componentribosome
c0006412biological_processtranslation
c0019843molecular_functionrRNA binding
c0022627cellular_componentcytosolic small ribosomal subunit
c1990904cellular_componentribonucleoprotein complex
d0000028biological_processribosomal small subunit assembly
d0000900molecular_functionmRNA regulatory element binding translation repressor activity
d0002181biological_processcytoplasmic translation
d0003723molecular_functionRNA binding
d0003735molecular_functionstructural constituent of ribosome
d0005515molecular_functionprotein binding
d0005737cellular_componentcytoplasm
d0005829cellular_componentcytosol
d0005840cellular_componentribosome
d0006353biological_processDNA-templated transcription termination
d0006412biological_processtranslation
d0006417biological_processregulation of translation
d0015935cellular_componentsmall ribosomal subunit
d0019843molecular_functionrRNA binding
d0022627cellular_componentcytosolic small ribosomal subunit
d0031564biological_processtranscription antitermination
d0042254biological_processribosome biogenesis
d0042274biological_processribosomal small subunit biogenesis
d0045947biological_processnegative regulation of translational initiation
d0046677biological_processresponse to antibiotic
d0048027molecular_functionmRNA 5'-UTR binding
d1990145biological_processmaintenance of translational fidelity
d1990904cellular_componentribonucleoprotein complex
e0000028biological_processribosomal small subunit assembly
e0002181biological_processcytoplasmic translation
e0003723molecular_functionRNA binding
e0003735molecular_functionstructural constituent of ribosome
e0005515molecular_functionprotein binding
e0005737cellular_componentcytoplasm
e0005829cellular_componentcytosol
e0005840cellular_componentribosome
e0006412biological_processtranslation
e0015935cellular_componentsmall ribosomal subunit
e0019843molecular_functionrRNA binding
e0022627cellular_componentcytosolic small ribosomal subunit
e0046677biological_processresponse to antibiotic
e1990145biological_processmaintenance of translational fidelity
e1990904cellular_componentribonucleoprotein complex
f0000028biological_processribosomal small subunit assembly
f0003735molecular_functionstructural constituent of ribosome
f0005737cellular_componentcytoplasm
f0005840cellular_componentribosome
f0006412biological_processtranslation
f0019843molecular_functionrRNA binding
f0022627cellular_componentcytosolic small ribosomal subunit
f0070181molecular_functionsmall ribosomal subunit rRNA binding
f1990904cellular_componentribonucleoprotein complex
g0003723molecular_functionRNA binding
g0003735molecular_functionstructural constituent of ribosome
g0006412biological_processtranslation
g0015935cellular_componentsmall ribosomal subunit
h0003735molecular_functionstructural constituent of ribosome
h0005840cellular_componentribosome
h0006412biological_processtranslation
i0003735molecular_functionstructural constituent of ribosome
i0005840cellular_componentribosome
i0006412biological_processtranslation
j0003723molecular_functionRNA binding
j0003735molecular_functionstructural constituent of ribosome
j0005840cellular_componentribosome
j0006412biological_processtranslation
k0003735molecular_functionstructural constituent of ribosome
k0005840cellular_componentribosome
k0006412biological_processtranslation
k0019843molecular_functionrRNA binding
k0022627cellular_componentcytosolic small ribosomal subunit
k1990904cellular_componentribonucleoprotein complex
l0000049molecular_functiontRNA binding
l0003735molecular_functionstructural constituent of ribosome
l0005840cellular_componentribosome
l0006412biological_processtranslation
l0015935cellular_componentsmall ribosomal subunit
l0019843molecular_functionrRNA binding
l1990904cellular_componentribonucleoprotein complex
m0000049molecular_functiontRNA binding
m0003676molecular_functionnucleic acid binding
m0003723molecular_functionRNA binding
m0003735molecular_functionstructural constituent of ribosome
m0005829cellular_componentcytosol
m0005840cellular_componentribosome
m0006412biological_processtranslation
m0015935cellular_componentsmall ribosomal subunit
m0019843molecular_functionrRNA binding
m1990904cellular_componentribonucleoprotein complex
n0003735molecular_functionstructural constituent of ribosome
n0005840cellular_componentribosome
n0006412biological_processtranslation
o0003735molecular_functionstructural constituent of ribosome
o0005840cellular_componentribosome
o0006412biological_processtranslation
p0000028biological_processribosomal small subunit assembly
p0003735molecular_functionstructural constituent of ribosome
p0005737cellular_componentcytoplasm
p0005840cellular_componentribosome
p0006412biological_processtranslation
p0015935cellular_componentsmall ribosomal subunit
p0022627cellular_componentcytosolic small ribosomal subunit
p1990904cellular_componentribonucleoprotein complex
q0003735molecular_functionstructural constituent of ribosome
q0005840cellular_componentribosome
q0006412biological_processtranslation
r0003735molecular_functionstructural constituent of ribosome
r0005840cellular_componentribosome
r0006412biological_processtranslation
r0019843molecular_functionrRNA binding
r0070181molecular_functionsmall ribosomal subunit rRNA binding
r1990904cellular_componentribonucleoprotein complex
s0003723molecular_functionRNA binding
s0003735molecular_functionstructural constituent of ribosome
s0005840cellular_componentribosome
s0006412biological_processtranslation
s0015935cellular_componentsmall ribosomal subunit
t0000028biological_processribosomal small subunit assembly
t0003723molecular_functionRNA binding
t0003735molecular_functionstructural constituent of ribosome
t0005829cellular_componentcytosol
t0005840cellular_componentribosome
t0006412biological_processtranslation
t0015935cellular_componentsmall ribosomal subunit
t0019843molecular_functionrRNA binding
t0022627cellular_componentcytosolic small ribosomal subunit
t0070181molecular_functionsmall ribosomal subunit rRNA binding
t1990904cellular_componentribonucleoprotein complex
u0003735molecular_functionstructural constituent of ribosome
u0005840cellular_componentribosome
u0006412biological_processtranslation
u1990904cellular_componentribonucleoprotein complex
Functional Information from PROSITE/UniProt
site_idPS00049
Number of Residues27
DetailsRIBOSOMAL_L14 Ribosomal protein L14 signature. AVVVrtkkgvrrp.DGsvirFdgNacVL
ChainResidueDetails
MALA60-LEU86

site_idPS00050
Number of Residues16
DetailsRIBOSOMAL_L23 Ribosomal protein L23 signature. KKAYVTLKegqnldfV
ChainResidueDetails
VLYS81-VAL96

site_idPS00052
Number of Residues27
DetailsRIBOSOMAL_S7 Ribosomal protein S7 signature. SeLlakFVnilmvdGKKstaesIVysA
ChainResidueDetails
gSER20-ALA46

site_idPS00053
Number of Residues18
DetailsRIBOSOMAL_S8 Ribosomal protein S8 signature. GiaVVSTSkGVMtdraAR
ChainResidueDetails
hGLY100-ARG117

site_idPS00054
Number of Residues23
DetailsRIBOSOMAL_S11 Ribosomal protein S11 signature. IrALnaA.GFrItnitDvTPiPHD
ChainResidueDetails
kILE97-IAS119

site_idPS00055
Number of Residues8
DetailsRIBOSOMAL_S12 Ribosomal protein S12 signature. KkPNSAlR
ChainResidueDetails
lLYS43-ARG50

site_idPS00056
Number of Residues13
DetailsRIBOSOMAL_S17 Ribosomal protein S17 signature. GDvVeIrEcRPLS
ChainResidueDetails
qGLY56-SER68

site_idPS00057
Number of Residues24
DetailsRIBOSOMAL_S18 Ribosomal protein S18 signature. IDYkd.IatLknYITEs.GKIvpsRI
ChainResidueDetails
rILE21-ILE44

site_idPS00061
Number of Residues29
DetailsADH_SHORT Short-chain dehydrogenases/reductases family signature. PdhkhavialTsiYGVGKTRSkAILaAAG
ChainResidueDetails
mPRO10-GLY38

site_idPS00323
Number of Residues25
DetailsRIBOSOMAL_S19 Ribosomal protein S19 signature. NGRqhvpvfVtdemVGhkLGEFapT
ChainResidueDetails
sASN53-THR77

site_idPS00358
Number of Residues17
DetailsRIBOSOMAL_L5 Ribosomal protein L5 signature. LaaISGQkpLiTkARkS
ChainResidueDetails
FLEU57-SER73

site_idPS00360
Number of Residues19
DetailsRIBOSOMAL_S9 Ribosomal protein S9 signature. GGGisGQagAirhGiTRAL
ChainResidueDetails
iGLY69-LEU87

site_idPS00361
Number of Residues16
DetailsRIBOSOMAL_S10 Ribosomal protein S10 signature. AkrtGAqvrGPIpLPT
ChainResidueDetails
jALA29-THR44

site_idPS00362
Number of Residues31
DetailsRIBOSOMAL_S15 Ribosomal protein S15 signature. LqgHFaehKkDhhSrrgLlrMvsqrrkLldY
ChainResidueDetails
oLEU39-TYR69

site_idPS00430
Number of Residues66
DetailsTONB_DEPENDENT_REC_1 TonB-dependent receptor (TBDR) proteins signature 1. mireerllkvlraphvsekastameksntivlkvakdatkaeikaavqklfevevevv.........................................................NTLVVKGK
ChainResidueDetails
VMET1-LYS66

site_idPS00464
Number of Residues25
DetailsRIBOSOMAL_L22 Ribosomal protein L22 signature. KriMpRAkGRadrilkrtSHITVvV
ChainResidueDetails
ULYS83-VAL107

site_idPS00467
Number of Residues12
DetailsRIBOSOMAL_L2 Ribosomal protein L2 signature. PtvRGTAmNPvD
ChainResidueDetails
CPRO218-ASP229

site_idPS00474
Number of Residues24
DetailsRIBOSOMAL_L3 Ribosomal protein L3 signature. FadvkkvDvtGtSkGKGfaGtvkR
ChainResidueDetails
DPHE101-ARG124

site_idPS00475
Number of Residues31
DetailsRIBOSOMAL_L15 Ribosomal protein L15 signature. KVILaGeVttp..VtVrglrVTkgAraaIeaaG
ChainResidueDetails
NLYS109-GLY139

site_idPS00525
Number of Residues9
DetailsRIBOSOMAL_L6_1 Ribosomal protein L6 signature 1. PEpYKGKGV
ChainResidueDetails
GPRO154-VAL162

site_idPS00527
Number of Residues23
DetailsRIBOSOMAL_S14 Ribosomal protein S14 signature. R.CrqtgrphgflrkFGLSRiKVR
ChainResidueDetails
nARG63-ARG85

site_idPS00548
Number of Residues35
DetailsRIBOSOMAL_S3 Ribosomal protein S3 signature. ARtewyreGrVplHt..LradIDyntseahTtyGviG
ChainResidueDetails
cALA163-GLY197

site_idPS00579
Number of Residues15
DetailsRIBOSOMAL_L29 Ribosomal protein L29 signature. QSHLLKqVRRDVARV
ChainResidueDetails
1GLN39-VAL53

site_idPS00582
Number of Residues20
DetailsRIBOSOMAL_L33 Ribosomal protein L33 signature. YtTtKNkrtkPekLElkKFD
ChainResidueDetails
5TYR21-ASP40

site_idPS00585
Number of Residues33
DetailsRIBOSOMAL_S5 Ribosomal protein S5 signature. GRifsFtAltVVGDgn.GrVGfGygkar.EVpa.AI
ChainResidueDetails
eGLY28-ILE60

site_idPS00586
Number of Residues12
DetailsRIBOSOMAL_L16_1 Ribosomal protein L16 signature 1. KRqGKIWIRVFP
ChainResidueDetails
OLYS58-PRO69

site_idPS00632
Number of Residues25
DetailsRIBOSOMAL_S4 Ribosomal protein S4 signature. LEgRLdnvVYRmgfGaTraeARqLV
ChainResidueDetails
dLEU94-VAL118

site_idPS00634
Number of Residues33
DetailsRIBOSOMAL_L30 Ribosomal protein L30 signature. TLlgLgLrRigHtVeredtpairgMInaVsfMV
ChainResidueDetails
2THR23-VAL55

site_idPS00646
Number of Residues14
DetailsRIBOSOMAL_S13_1 Ribosomal protein S13 signature. RGlRHrrGlpVRGQ
ChainResidueDetails
mARG87-GLN100

site_idPS00651
Number of Residues28
DetailsRIBOSOMAL_L9 Ribosomal protein L9 signature. GslGdqvnVkaGYarNFLvpqgkAvpaT
ChainResidueDetails
HGLY13-THR40

site_idPS00732
Number of Residues10
DetailsRIBOSOMAL_S16 Ribosomal protein S16 signature. VtIRLARHGA
ChainResidueDetails
pVAL2-ALA11

site_idPS00783
Number of Residues23
DetailsRIBOSOMAL_L13 Ribosomal protein L13 signature. VKGMLPkgpl.GRamfrkLkVYaG
ChainResidueDetails
LVAL105-GLY127

site_idPS00784
Number of Residues20
DetailsRIBOSOMAL_L34 Ribosomal protein L34 signature. KRTFQpsvlkRnrsh.GFraR
ChainResidueDetails
6LYS2-ARG21

site_idPS00828
Number of Residues27
DetailsRIBOSOMAL_L36 Ribosomal protein L36 signature. CrnCkiVkRdgvIrViCsaepKHkQrQ
ChainResidueDetails
8CYS11-GLN37

site_idPS00831
Number of Residues15
DetailsRIBOSOMAL_L27 Ribosomal protein L27 signature. GsIIvRQRGtkfhaG
ChainResidueDetails
YGLY34-GLY48

site_idPS00936
Number of Residues27
DetailsRIBOSOMAL_L35 Ribosomal protein L35 signature. KTVrGAaKRFkktgkggfkhkhanl.RH
ChainResidueDetails
7LYS5-HIS31

site_idPS00937
Number of Residues17
DetailsRIBOSOMAL_L20 Ribosomal protein L20 signature. KrqfRqLWIARINaaaR
ChainResidueDetails
SLYS54-ARG70

site_idPS00962
Number of Residues12
DetailsRIBOSOMAL_S2_1 Ribosomal protein S2 signature 1. MrDMLKAGVHFG
ChainResidueDetails
bMET6-GLY17

site_idPS00963
Number of Residues25
DetailsRIBOSOMAL_S2_2 Ribosomal protein S2 signature 2. PdaLFViDadhEhiaIkEannlGIP
ChainResidueDetails
bPRO158-PRO182

site_idPS01015
Number of Residues16
DetailsRIBOSOMAL_L19 Ribosomal protein L19 signature. VkRrGAVR.KAKLYYLR
ChainResidueDetails
RVAL86-ARG101

site_idPS01048
Number of Residues10
DetailsRIBOSOMAL_S6 Ribosomal protein S6 signature. GrRQLAYpIN
ChainResidueDetails
fGLY43-ASN52

site_idPS01108
Number of Residues18
DetailsRIBOSOMAL_L24 Ribosomal protein L24 signature. DDeViVLtGkdKGkr.GkV
ChainResidueDetails
WASP8-VAL25

site_idPS01143
Number of Residues22
DetailsRIBOSOMAL_L31 Ribosomal protein L31 signature. DVcskcHPFFTgkqrdvatg....GR
ChainResidueDetails
3ASP35-ARG56

site_idPS01167
Number of Residues23
DetailsRIBOSOMAL_L17 Ribosomal protein L17 signature. IkTTlpKaKelrrvvEpLITlAK
ChainResidueDetails
PILE34-LYS56

site_idPS01169
Number of Residues23
DetailsRIBOSOMAL_L21 Ribosomal protein L21 signature. VkivKfrrRKhyrkqqGHRQwfT
ChainResidueDetails
TVAL72-THR94

site_idPS01181
Number of Residues13
DetailsRIBOSOMAL_S21 Ribosomal protein S21 signature. DvALRRFKRsceK
ChainResidueDetails
uASP13-LYS25

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsMOD_RES: N-acetylalanine => ECO:0000269|PubMed:776663
ChainResidueDetails
rALA2
HLYS83
HLYS112

site_idSWS_FT_FI2
Number of Residues1
DetailsMOD_RES: N6-acetyllysine => ECO:0000269|PubMed:18723842
ChainResidueDetails
lLYS108

226707

PDB entries from 2024-10-30

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