8G4B
Crystal structure of heterodimeric Crotoxin B from Crotalus durissus collilineatus
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Region: {"description":"Putative region that binds to the R48 receptor (PubMed:21787789)","evidences":[{"source":"PubMed","id":"21787789","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Active site: {"evidences":[{"source":"UniProtKB","id":"P62022","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P62022","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 10 |
| Details | Site: {"description":"Putative interfacial binding surface (IBS)","evidences":[{"source":"PubMed","id":"21787789","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Site: {"description":"Binds Q-49 of CBa2","evidences":[{"source":"PubMed","id":"21787789","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | Site: {"description":"Binds G-45 of CBa2","evidences":[{"source":"PubMed","id":"21787789","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | Site: {"description":"Binds D-105 of CBa2, important for stability (T-31)","evidences":[{"source":"PubMed","id":"21787789","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 1 |
| Details | Site: {"description":"Binds E-93 of CBa2","evidences":[{"source":"PubMed","id":"21787789","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 1 |
| Details | Site: {"description":"Binds D-95 of CBa2, important for stability (T-70)","evidences":[{"source":"PubMed","id":"21787789","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI10 |
| Number of Residues | 1 |
| Details | Site: {"description":"Responsible for the weak stability and toxicity","evidences":[{"source":"UniProtKB","id":"P62022","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI11 |
| Number of Residues | 9 |
| Details | Site: {"description":"Putative interfacial binding surface (IBS)","evidences":[{"source":"UniProtKB","id":"P62022","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI12 |
| Number of Residues | 1 |
| Details | Site: {"description":"Responsible for the higher anticoagulant activity (compared with CBa2)","evidences":[{"source":"UniProtKB","id":"P62022","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
