8FY8
5-MeO-DMT-bound serotonin 1A (5-HT1A) receptor-Gi1 protein complex
Functional Information from PROSITE/UniProt
| site_id | PS00237 |
| Number of Residues | 17 |
| Details | G_PROTEIN_RECEP_F1_1 G-protein coupled receptors family 1 signature. SSIwHLCAIALDRYWaI |
| Chain | Residue | Details |
| R | SER122-ILE138 |
| site_id | PS00678 |
| Number of Residues | 15 |
| Details | WD_REPEATS_1 Trp-Asp (WD) repeats signature. LVSAsqDgKLIIWDS |
| Chain | Residue | Details |
| B | LEU70-SER84 | |
| B | ILE157-ILE171 | |
| B | LEU285-ALA299 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 25 |
| Details | TRANSMEM: Helical; Name=1 => ECO:0000250 |
| Chain | Residue | Details |
| R | VAL37-ALA62 | |
| A | ASN269 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 174 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000250 |
| Chain | Residue | Details |
| R | LEU63-TYR73 | |
| R | ASP133-ARG152 | |
| R | ILE218-LYS345 | |
| R | ASN404-GLN422 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 24 |
| Details | TRANSMEM: Helical; Name=2 => ECO:0000250 |
| Chain | Residue | Details |
| R | LEU74-VAL98 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 33 |
| Details | TOPO_DOM: Extracellular => ECO:0000250 |
| Chain | Residue | Details |
| R | LEU99-ASP110 | |
| R | GLU179-LYS191 | |
| R | LEU368-PRO378 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 21 |
| Details | TRANSMEM: Helical; Name=3 => ECO:0000250 |
| Chain | Residue | Details |
| R | LEU111-LEU132 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 25 |
| Details | TRANSMEM: Helical; Name=4 => ECO:0000250 |
| Chain | Residue | Details |
| R | ALA153-PRO178 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 25 |
| Details | TRANSMEM: Helical; Name=5 => ECO:0000250 |
| Chain | Residue | Details |
| R | ASP192-ARG217 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 21 |
| Details | TRANSMEM: Helical; Name=6 => ECO:0000250 |
| Chain | Residue | Details |
| R | THR346-VAL367 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 24 |
| Details | TRANSMEM: Helical; Name=7 => ECO:0000250 |
| Chain | Residue | Details |
| R | THR379-PHE403 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:P28222 |
| Chain | Residue | Details |
| R | ASP116 | |
| R | THR121 | |
| R | ILE189 |
| site_id | SWS_FT_FI11 |
| Number of Residues | 1 |
| Details | LIPID: S-palmitoyl cysteine => ECO:0000250|UniProtKB:P10824 |
| Chain | Residue | Details |
| A | CYS3 |
