8FV7

E coli. CTP synthase in complex with dF-dCTP + ATP

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
AAA	0000166	molecular_function	nucleotide binding
AAA	0000287	molecular_function	magnesium ion binding
AAA	0003883	molecular_function	CTP synthase activity
AAA	0004359	molecular_function	glutaminase activity
AAA	0005524	molecular_function	ATP binding
AAA	0005737	cellular_component	cytoplasm
AAA	0005829	cellular_component	cytosol
AAA	0006221	biological_process	pyrimidine nucleotide biosynthetic process
AAA	0006241	biological_process	CTP biosynthetic process
AAA	0016874	molecular_function	ligase activity
AAA	0019856	biological_process	pyrimidine nucleobase biosynthetic process
AAA	0032991	cellular_component	protein-containing complex
AAA	0042802	molecular_function	identical protein binding
AAA	0044210	biological_process	'de novo' CTP biosynthetic process
AAA	0046872	molecular_function	metal ion binding
AAA	0051289	biological_process	protein homotetramerization
AAA	0097268	cellular_component	cytoophidium
BBB	0000166	molecular_function	nucleotide binding
BBB	0000287	molecular_function	magnesium ion binding
BBB	0003883	molecular_function	CTP synthase activity
BBB	0004359	molecular_function	glutaminase activity
BBB	0005524	molecular_function	ATP binding
BBB	0005737	cellular_component	cytoplasm
BBB	0005829	cellular_component	cytosol
BBB	0006221	biological_process	pyrimidine nucleotide biosynthetic process
BBB	0006241	biological_process	CTP biosynthetic process
BBB	0016874	molecular_function	ligase activity
BBB	0019856	biological_process	pyrimidine nucleobase biosynthetic process
BBB	0032991	cellular_component	protein-containing complex
BBB	0042802	molecular_function	identical protein binding
BBB	0044210	biological_process	'de novo' CTP biosynthetic process
BBB	0046872	molecular_function	metal ion binding
BBB	0051289	biological_process	protein homotetramerization
BBB	0097268	cellular_component	cytoophidium

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	530
Details	Region: {"description":"Amidoligase domain","evidences":[{"source":"HAMAP-Rule","id":"MF_01227","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Active site: {"description":"Nucleophile; for glutamine hydrolysis","evidences":[{"source":"PubMed","id":"11336655","evidenceCode":"ECO:0000305"},{"source":"PubMed","id":"15157079","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Active site: {"evidences":[{"source":"PubMed","id":"15157079","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	14
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16216072","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	18
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16216072","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"2AD5","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"16216072","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2AD5","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	12
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_01227","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	528
Details	Region: {"description":"Amidoligase domain","evidences":[{"source":"PubMed","id":"15157079","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---