8FUF
Crystal structure of human O-GlcNAc transferase (OGT) in complex with an exosite-binding peptide (ZNF831) and UDP-GlcNAc
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | ACT_SITE: Proton acceptor => ECO:0000305|PubMed:21240259, ECO:0000305|PubMed:26678539 |
| Chain | Residue | Details |
| A | HIS624 | |
| C | HIS624 | |
| E | HIS624 | |
| G | HIS624 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 16 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:23103939, ECO:0007744|PDB:4GYW |
| Chain | Residue | Details |
| A | GLU965 | |
| A | ASP968 | |
| A | LYS1022 | |
| A | ILE1027 | |
| C | GLU965 | |
| C | ASP968 | |
| C | LYS1022 | |
| C | ILE1027 | |
| E | GLU965 | |
| E | ASP968 | |
| E | LYS1022 | |
| E | ILE1027 | |
| G | GLU965 | |
| G | ASP968 | |
| G | LYS1022 | |
| G | ILE1027 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphothreonine; by AMPK => ECO:0000269|PubMed:24563466, ECO:0000269|PubMed:37541260 |
| Chain | Residue | Details |
| A | MET570 | |
| C | MET570 | |
| E | MET570 | |
| G | MET570 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | CARBOHYD: O-linked (GlcNAc) serine; by autocatalysis => ECO:0000269|PubMed:27713473 |
| Chain | Residue | Details |
| A | GLU515 | |
| C | GLU515 | |
| E | GLU515 | |
| G | GLU515 |
