8FQ9
Crystal structure of a ligand-bound cation-site mutant D55C of a melibiose transporter
Functional Information from PROSITE/UniProt
| site_id | PS00872 |
| Number of Residues | 26 |
| Details | NA_GALACTOSIDE_SYMP Sodium:galactoside symporter family signature. DpimGwivNatrsrw..GKFKPWILiGT |
| Chain | Residue | Details |
| A | ASP59-THR84 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 274 |
| Details | TRANSMEM: Helical => ECO:0000269|PubMed:34341464, ECO:0007744|PDB:7L16, ECO:0007744|PDB:7L17 |
| Chain | Residue | Details |
| A | LYS8-MET30 | |
| A | ALA324-VAL349 | |
| A | ILE367-ILE394 | |
| A | GLY409-ARG431 | |
| A | GLY42-VAL66 | |
| A | LYS77-ALA97 | |
| A | GLN105-SER129 | |
| A | LEU144-VAL167 | |
| A | GLY178-ASN200 | |
| A | LEU233-ILE255 | |
| A | LEU267-LEU289 | |
| A | ILE297-LEU318 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 52 |
| Details | TOPO_DOM: Periplasmic => ECO:0000269|PubMed:34341464, ECO:0007744|PDB:7L16, ECO:0007744|PDB:7L17 |
| Chain | Residue | Details |
| A | TYR31-VAL41 | |
| A | HIS98-ALA104 | |
| A | SER168-PHE177 | |
| A | TYR256-ASP266 | |
| A | ALA319-ASN323 | |
| A | GLY395-GLN408 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 119 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000269|PubMed:34341464, ECO:0007744|PDB:7L16, ECO:0007744|PDB:7L17 |
| Chain | Residue | Details |
| A | ASN67-PHE76 | |
| A | LEU130-GLN143 | |
| A | VAL201-GLN232 | |
| A | VAL290-ARG296 | |
| A | ALA350-SER366 | |
| A | TYR432-ALA476 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:34341464, ECO:0007744|PDB:7L17 |
| Chain | Residue | Details |
| A | LYS18 | |
| A | ASP124 | |
| A | TRP128 | |
| A | ARG149 |
