8FNN
Structure of E138K/G140A/Q148K HIV-1 intasome with Dolutegravir bound
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0015074 | biological_process | DNA integration |
| B | 0003676 | molecular_function | nucleic acid binding |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0015074 | biological_process | DNA integration |
| C | 0003676 | molecular_function | nucleic acid binding |
| C | 0008270 | molecular_function | zinc ion binding |
| C | 0015074 | biological_process | DNA integration |
| D | 0003676 | molecular_function | nucleic acid binding |
| D | 0008270 | molecular_function | zinc ion binding |
| D | 0015074 | biological_process | DNA integration |
| G | 0003676 | molecular_function | nucleic acid binding |
| G | 0008270 | molecular_function | zinc ion binding |
| G | 0015074 | biological_process | DNA integration |
| H | 0003676 | molecular_function | nucleic acid binding |
| H | 0008270 | molecular_function | zinc ion binding |
| H | 0015074 | biological_process | DNA integration |
| I | 0003676 | molecular_function | nucleic acid binding |
| I | 0008270 | molecular_function | zinc ion binding |
| I | 0015074 | biological_process | DNA integration |
| J | 0003676 | molecular_function | nucleic acid binding |
| J | 0008270 | molecular_function | zinc ion binding |
| J | 0015074 | biological_process | DNA integration |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 300 |
| Details | Domain: {"description":"Integrase catalytic","evidences":[{"source":"PROSITE-ProRule","id":"PRU00457","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 164 |
| Details | Zinc finger: {"description":"Integrase-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00450","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 16 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00450","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 8 |
| Details | Binding site: {} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"UniProtKB","id":"P04585","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 94 |
| Details | DNA binding: {"description":"Integrase-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00506","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
