8FGC

Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(5-(2-aminoethyl)-2,3-difluorophenethyl)-4-methylpyridin-2-amine

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004517	molecular_function	nitric-oxide synthase activity
A	0006809	biological_process	nitric oxide biosynthetic process
B	0004517	molecular_function	nitric-oxide synthase activity
B	0006809	biological_process	nitric oxide biosynthetic process

Functional Information from PROSITE/UniProt

site_id	PS60001
Number of Residues	8
Details	NOS Nitric oxide synthase (NOS) signature. RCVGRIqW

Chain	Residue	Details
A	ARG414-TRP421

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	18
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P29475

Chain	Residue	Details
A	SER334
B	SER335
B	GLN479
B	TRP588
B	TYR589
B	GLU593
B	VAL678
B	TRP679
B	PHE692
B	TYR707
A	GLN478
A	TRP587
A	TYR588
A	GLU592
A	VAL677
A	TRP678
A	PHE691
A	TYR706

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	BINDING: axial binding residue => ECO:0000250|UniProtKB:P29475

Chain	Residue	Details
A	CYS415
B	CYS416

---