8F7J

LRRC8A(T48D):C conformation 2 top focus

Functional Information from GO Data

Chain	GOid	namespace	contents
E	0005506	molecular_function	iron ion binding
E	0009055	molecular_function	electron transfer activity
E	0020037	molecular_function	heme binding
E	0022900	biological_process	electron transport chain
E	0042597	cellular_component	periplasmic space
E	0046872	molecular_function	metal ion binding

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	610
Details	TOPO_DOM: Cytoplasmic => ECO:0000305|PubMed:29769723

Chain	Residue	Details
E	MET-91-PRO-70
E	TRP143-TYR264
E	TRP342-ALA810

---

site_id	SWS_FT_FI2
Number of Residues	87
Details	TRANSMEM: Helical => ECO:0000305|PubMed:30775971, ECO:0007744|PDB:6NZW, ECO:0007744|PDB:6NZZ, ECO:0007744|PDB:6O00

Chain	Residue	Details
E	TRP-69-VAL-45
E	TYR124-PHE142
E	MET265-VAL286
E	LEU317-TRP341

---

site_id	SWS_FT_FI3
Number of Residues	29
Details	TOPO_DOM: Extracellular => ECO:0000305|PubMed:29769723

Chain	Residue	Details
E	HIS287-THR316

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	SITE: Required for anion selectivity => ECO:0000250|UniProtKB:Q8IWT6

Chain	Residue	Details
E	ARG103

---

site_id	SWS_FT_FI5
Number of Residues	1
Details	MOD_RES: N-acetylmethionine => ECO:0000250|UniProtKB:Q8IWT6

Chain	Residue	Details
E	MET-91

---

site_id	SWS_FT_FI6
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:21183079

Chain	Residue	Details
E	THR200

---

site_id	SWS_FT_FI7
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:21183079

Chain	Residue	Details
E	SER202

---

site_id	SWS_FT_FI8
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:Q8IWT6

Chain	Residue	Details
E	THR215

---

site_id	SWS_FT_FI9
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q8IWT6

Chain	Residue	Details
E	SER217

---

site_id	SWS_FT_FI10
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
E	ASN-26

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site_id	SWS_FT_FI11
Number of Residues	2
Details	BINDING: axial binding residue

Chain	Residue	Details
E	TRP-9
E	ILE86

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