8F7C

Cryo-EM structure of human pannexin 2

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005506	molecular_function	iron ion binding
A	0006812	biological_process	monoatomic cation transport
A	0009055	molecular_function	electron transfer activity
A	0015267	molecular_function	channel activity
A	0020037	molecular_function	heme binding
A	0022900	biological_process	electron transport chain
A	0032732	biological_process	positive regulation of interleukin-1 production
A	0042597	cellular_component	periplasmic space
A	0046872	molecular_function	metal ion binding
B	0005506	molecular_function	iron ion binding
B	0006812	biological_process	monoatomic cation transport
B	0009055	molecular_function	electron transfer activity
B	0015267	molecular_function	channel activity
B	0020037	molecular_function	heme binding
B	0022900	biological_process	electron transport chain
B	0032732	biological_process	positive regulation of interleukin-1 production
B	0042597	cellular_component	periplasmic space
B	0046872	molecular_function	metal ion binding
C	0005506	molecular_function	iron ion binding
C	0006812	biological_process	monoatomic cation transport
C	0009055	molecular_function	electron transfer activity
C	0015267	molecular_function	channel activity
C	0020037	molecular_function	heme binding
C	0022900	biological_process	electron transport chain
C	0032732	biological_process	positive regulation of interleukin-1 production
C	0042597	cellular_component	periplasmic space
C	0046872	molecular_function	metal ion binding
D	0005506	molecular_function	iron ion binding
D	0006812	biological_process	monoatomic cation transport
D	0009055	molecular_function	electron transfer activity
D	0015267	molecular_function	channel activity
D	0020037	molecular_function	heme binding
D	0022900	biological_process	electron transport chain
D	0032732	biological_process	positive regulation of interleukin-1 production
D	0042597	cellular_component	periplasmic space
D	0046872	molecular_function	metal ion binding
E	0005506	molecular_function	iron ion binding
E	0006812	biological_process	monoatomic cation transport
E	0009055	molecular_function	electron transfer activity
E	0015267	molecular_function	channel activity
E	0020037	molecular_function	heme binding
E	0022900	biological_process	electron transport chain
E	0032732	biological_process	positive regulation of interleukin-1 production
E	0042597	cellular_component	periplasmic space
E	0046872	molecular_function	metal ion binding
F	0005506	molecular_function	iron ion binding
F	0006812	biological_process	monoatomic cation transport
F	0009055	molecular_function	electron transfer activity
F	0015267	molecular_function	channel activity
F	0020037	molecular_function	heme binding
F	0022900	biological_process	electron transport chain
F	0032732	biological_process	positive regulation of interleukin-1 production
F	0042597	cellular_component	periplasmic space
F	0046872	molecular_function	metal ion binding
G	0005506	molecular_function	iron ion binding
G	0006812	biological_process	monoatomic cation transport
G	0009055	molecular_function	electron transfer activity
G	0015267	molecular_function	channel activity
G	0020037	molecular_function	heme binding
G	0022900	biological_process	electron transport chain
G	0032732	biological_process	positive regulation of interleukin-1 production
G	0042597	cellular_component	periplasmic space
G	0046872	molecular_function	metal ion binding

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	616
Details	Transmembrane: {"description":"Helical","evidences":[{"source":"PROSITE-ProRule","id":"PRU00351","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	364
Details	Topological domain: {"description":"Extracellular","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	7
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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