8F2L

Crystal structure of Mycobacterium tuberculosis Homoserine transacetylase in complex with L-Homoserine

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004414	molecular_function	homoserine O-acetyltransferase activity
A	0005737	cellular_component	cytoplasm
A	0005886	cellular_component	plasma membrane
A	0008652	biological_process	amino acid biosynthetic process
A	0009058	biological_process	biosynthetic process
A	0009086	biological_process	methionine biosynthetic process
A	0016740	molecular_function	transferase activity
A	0016746	molecular_function	acyltransferase activity
A	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
B	0003824	molecular_function	catalytic activity
B	0004414	molecular_function	homoserine O-acetyltransferase activity
B	0005737	cellular_component	cytoplasm
B	0005886	cellular_component	plasma membrane
B	0008652	biological_process	amino acid biosynthetic process
B	0009058	biological_process	biosynthetic process
B	0009086	biological_process	methionine biosynthetic process
B	0016740	molecular_function	transferase activity
B	0016746	molecular_function	acyltransferase activity
B	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
C	0003824	molecular_function	catalytic activity
C	0004414	molecular_function	homoserine O-acetyltransferase activity
C	0005737	cellular_component	cytoplasm
C	0005886	cellular_component	plasma membrane
C	0008652	biological_process	amino acid biosynthetic process
C	0009058	biological_process	biosynthetic process
C	0009086	biological_process	methionine biosynthetic process
C	0016740	molecular_function	transferase activity
C	0016746	molecular_function	acyltransferase activity
C	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
D	0003824	molecular_function	catalytic activity
D	0004414	molecular_function	homoserine O-acetyltransferase activity
D	0005737	cellular_component	cytoplasm
D	0005886	cellular_component	plasma membrane
D	0008652	biological_process	amino acid biosynthetic process
D	0009058	biological_process	biosynthetic process
D	0009086	biological_process	methionine biosynthetic process
D	0016740	molecular_function	transferase activity
D	0016746	molecular_function	acyltransferase activity
D	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
E	0003824	molecular_function	catalytic activity
E	0004414	molecular_function	homoserine O-acetyltransferase activity
E	0005737	cellular_component	cytoplasm
E	0005886	cellular_component	plasma membrane
E	0008652	biological_process	amino acid biosynthetic process
E	0009058	biological_process	biosynthetic process
E	0009086	biological_process	methionine biosynthetic process
E	0016740	molecular_function	transferase activity
E	0016746	molecular_function	acyltransferase activity
E	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
F	0003824	molecular_function	catalytic activity
F	0004414	molecular_function	homoserine O-acetyltransferase activity
F	0005737	cellular_component	cytoplasm
F	0005886	cellular_component	plasma membrane
F	0008652	biological_process	amino acid biosynthetic process
F	0009058	biological_process	biosynthetic process
F	0009086	biological_process	methionine biosynthetic process
F	0016740	molecular_function	transferase activity
F	0016746	molecular_function	acyltransferase activity
F	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
G	0003824	molecular_function	catalytic activity
G	0004414	molecular_function	homoserine O-acetyltransferase activity
G	0005737	cellular_component	cytoplasm
G	0005886	cellular_component	plasma membrane
G	0008652	biological_process	amino acid biosynthetic process
G	0009058	biological_process	biosynthetic process
G	0009086	biological_process	methionine biosynthetic process
G	0016740	molecular_function	transferase activity
G	0016746	molecular_function	acyltransferase activity
G	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
H	0003824	molecular_function	catalytic activity
H	0004414	molecular_function	homoserine O-acetyltransferase activity
H	0005737	cellular_component	cytoplasm
H	0005886	cellular_component	plasma membrane
H	0008652	biological_process	amino acid biosynthetic process
H	0009058	biological_process	biosynthetic process
H	0009086	biological_process	methionine biosynthetic process
H	0016740	molecular_function	transferase activity
H	0016746	molecular_function	acyltransferase activity
H	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
I	0003824	molecular_function	catalytic activity
I	0004414	molecular_function	homoserine O-acetyltransferase activity
I	0005737	cellular_component	cytoplasm
I	0005886	cellular_component	plasma membrane
I	0008652	biological_process	amino acid biosynthetic process
I	0009058	biological_process	biosynthetic process
I	0009086	biological_process	methionine biosynthetic process
I	0016740	molecular_function	transferase activity
I	0016746	molecular_function	acyltransferase activity
I	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
J	0003824	molecular_function	catalytic activity
J	0004414	molecular_function	homoserine O-acetyltransferase activity
J	0005737	cellular_component	cytoplasm
J	0005886	cellular_component	plasma membrane
J	0008652	biological_process	amino acid biosynthetic process
J	0009058	biological_process	biosynthetic process
J	0009086	biological_process	methionine biosynthetic process
J	0016740	molecular_function	transferase activity
J	0016746	molecular_function	acyltransferase activity
J	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
K	0003824	molecular_function	catalytic activity
K	0004414	molecular_function	homoserine O-acetyltransferase activity
K	0005737	cellular_component	cytoplasm
K	0005886	cellular_component	plasma membrane
K	0008652	biological_process	amino acid biosynthetic process
K	0009058	biological_process	biosynthetic process
K	0009086	biological_process	methionine biosynthetic process
K	0016740	molecular_function	transferase activity
K	0016746	molecular_function	acyltransferase activity
K	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups
L	0003824	molecular_function	catalytic activity
L	0004414	molecular_function	homoserine O-acetyltransferase activity
L	0005737	cellular_component	cytoplasm
L	0005886	cellular_component	plasma membrane
L	0008652	biological_process	amino acid biosynthetic process
L	0009058	biological_process	biosynthetic process
L	0009086	biological_process	methionine biosynthetic process
L	0016740	molecular_function	transferase activity
L	0016746	molecular_function	acyltransferase activity
L	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3648
Details	Domain: {"description":"AB hydrolase-1","evidences":[{"source":"HAMAP-Rule","id":"MF_00296","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	12
Details	Active site: {"description":"Nucleophile","evidences":[{"source":"HAMAP-Rule","id":"MF_00296","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	24
Details	Active site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00296","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	24
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00296","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---