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8F2L

Crystal structure of Mycobacterium tuberculosis Homoserine transacetylase in complex with L-Homoserine

Functional Information from GO Data
ChainGOidnamespacecontents
A0004414molecular_functionhomoserine O-acetyltransferase activity
A0005737cellular_componentcytoplasm
A0005886cellular_componentplasma membrane
A0008652biological_processamino acid biosynthetic process
A0009058biological_processbiosynthetic process
A0009086biological_processmethionine biosynthetic process
A0016740molecular_functiontransferase activity
A0016746molecular_functionacyltransferase activity
A0016747molecular_functionacyltransferase activity, transferring groups other than amino-acyl groups
B0004414molecular_functionhomoserine O-acetyltransferase activity
B0005737cellular_componentcytoplasm
B0005886cellular_componentplasma membrane
B0008652biological_processamino acid biosynthetic process
B0009058biological_processbiosynthetic process
B0009086biological_processmethionine biosynthetic process
B0016740molecular_functiontransferase activity
B0016746molecular_functionacyltransferase activity
B0016747molecular_functionacyltransferase activity, transferring groups other than amino-acyl groups
C0004414molecular_functionhomoserine O-acetyltransferase activity
C0005737cellular_componentcytoplasm
C0005886cellular_componentplasma membrane
C0008652biological_processamino acid biosynthetic process
C0009058biological_processbiosynthetic process
C0009086biological_processmethionine biosynthetic process
C0016740molecular_functiontransferase activity
C0016746molecular_functionacyltransferase activity
C0016747molecular_functionacyltransferase activity, transferring groups other than amino-acyl groups
D0004414molecular_functionhomoserine O-acetyltransferase activity
D0005737cellular_componentcytoplasm
D0005886cellular_componentplasma membrane
D0008652biological_processamino acid biosynthetic process
D0009058biological_processbiosynthetic process
D0009086biological_processmethionine biosynthetic process
D0016740molecular_functiontransferase activity
D0016746molecular_functionacyltransferase activity
D0016747molecular_functionacyltransferase activity, transferring groups other than amino-acyl groups
E0004414molecular_functionhomoserine O-acetyltransferase activity
E0005737cellular_componentcytoplasm
E0005886cellular_componentplasma membrane
E0008652biological_processamino acid biosynthetic process
E0009058biological_processbiosynthetic process
E0009086biological_processmethionine biosynthetic process
E0016740molecular_functiontransferase activity
E0016746molecular_functionacyltransferase activity
E0016747molecular_functionacyltransferase activity, transferring groups other than amino-acyl groups
F0004414molecular_functionhomoserine O-acetyltransferase activity
F0005737cellular_componentcytoplasm
F0005886cellular_componentplasma membrane
F0008652biological_processamino acid biosynthetic process
F0009058biological_processbiosynthetic process
F0009086biological_processmethionine biosynthetic process
F0016740molecular_functiontransferase activity
F0016746molecular_functionacyltransferase activity
F0016747molecular_functionacyltransferase activity, transferring groups other than amino-acyl groups
G0004414molecular_functionhomoserine O-acetyltransferase activity
G0005737cellular_componentcytoplasm
G0005886cellular_componentplasma membrane
G0008652biological_processamino acid biosynthetic process
G0009058biological_processbiosynthetic process
G0009086biological_processmethionine biosynthetic process
G0016740molecular_functiontransferase activity
G0016746molecular_functionacyltransferase activity
G0016747molecular_functionacyltransferase activity, transferring groups other than amino-acyl groups
H0004414molecular_functionhomoserine O-acetyltransferase activity
H0005737cellular_componentcytoplasm
H0005886cellular_componentplasma membrane
H0008652biological_processamino acid biosynthetic process
H0009058biological_processbiosynthetic process
H0009086biological_processmethionine biosynthetic process
H0016740molecular_functiontransferase activity
H0016746molecular_functionacyltransferase activity
H0016747molecular_functionacyltransferase activity, transferring groups other than amino-acyl groups
I0004414molecular_functionhomoserine O-acetyltransferase activity
I0005737cellular_componentcytoplasm
I0005886cellular_componentplasma membrane
I0008652biological_processamino acid biosynthetic process
I0009058biological_processbiosynthetic process
I0009086biological_processmethionine biosynthetic process
I0016740molecular_functiontransferase activity
I0016746molecular_functionacyltransferase activity
I0016747molecular_functionacyltransferase activity, transferring groups other than amino-acyl groups
J0004414molecular_functionhomoserine O-acetyltransferase activity
J0005737cellular_componentcytoplasm
J0005886cellular_componentplasma membrane
J0008652biological_processamino acid biosynthetic process
J0009058biological_processbiosynthetic process
J0009086biological_processmethionine biosynthetic process
J0016740molecular_functiontransferase activity
J0016746molecular_functionacyltransferase activity
J0016747molecular_functionacyltransferase activity, transferring groups other than amino-acyl groups
K0004414molecular_functionhomoserine O-acetyltransferase activity
K0005737cellular_componentcytoplasm
K0005886cellular_componentplasma membrane
K0008652biological_processamino acid biosynthetic process
K0009058biological_processbiosynthetic process
K0009086biological_processmethionine biosynthetic process
K0016740molecular_functiontransferase activity
K0016746molecular_functionacyltransferase activity
K0016747molecular_functionacyltransferase activity, transferring groups other than amino-acyl groups
L0004414molecular_functionhomoserine O-acetyltransferase activity
L0005737cellular_componentcytoplasm
L0005886cellular_componentplasma membrane
L0008652biological_processamino acid biosynthetic process
L0009058biological_processbiosynthetic process
L0009086biological_processmethionine biosynthetic process
L0016740molecular_functiontransferase activity
L0016746molecular_functionacyltransferase activity
L0016747molecular_functionacyltransferase activity, transferring groups other than amino-acyl groups
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues3648
DetailsDomain: {"description":"AB hydrolase-1","evidences":[{"source":"HAMAP-Rule","id":"MF_00296","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI2
Number of Residues12
DetailsActive site: {"description":"Nucleophile","evidences":[{"source":"HAMAP-Rule","id":"MF_00296","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI3
Number of Residues24
DetailsActive site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00296","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

site_idSWS_FT_FI4
Number of Residues24
DetailsBinding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00296","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

238895

PDB entries from 2025-07-16

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