8EZD
Brain-derived 42-residue amyloid-beta fibril type A
Functional Information from GO Data
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 200 |
| Details | Peptide: {"description":"P3(42)","featureId":"PRO_0000000095"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 184 |
| Details | Peptide: {"description":"P3(40)","featureId":"PRO_0000000096"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"10413512","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"11274207","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26898943","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"11274207","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"26898943","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 8 |
| Details | Site: {"description":"Cleavage; by alpha-secretase","evidences":[{"source":"PubMed","id":"11851430","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 8 |
| Details | Site: {"description":"Cleavage; by theta-secretase","evidences":[{"source":"PubMed","id":"16816112","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 8 |
| Details | Site: {"description":"Implicated in free radical propagation","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI8 |
| Number of Residues | 8 |
| Details | Site: {"description":"Susceptible to oxidation","evidences":[{"source":"PubMed","id":"10535332","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI9 |
| Number of Residues | 8 |
| Details | Site: {"description":"Cleavage; by gamma-secretase; site 1","evidences":[{"source":"PubMed","id":"11851430","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
