8ESI

Bile Salt Hydrolase from B. longum with covalent inhibitor bound

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0006629	biological_process	lipid metabolic process
A	0009274	cellular_component	peptidoglycan-based cell wall
A	0016740	molecular_function	transferase activity
A	0016787	molecular_function	hydrolase activity
A	0045302	molecular_function	choloylglycine hydrolase activity
A	0047742	molecular_function	chenodeoxycholoyltaurine hydrolase activity
A	7770003	molecular_function	amino acid conjugated cholate hydrolase activity
A	7770004	molecular_function	L-serine conjugated cholate hydrolase activity
A	7770005	molecular_function	L-alanine conjugated cholate hydrolase activity
A	7770008	molecular_function	L-histidine conjugated cholate hydrolase activity
B	0005515	molecular_function	protein binding
B	0006629	biological_process	lipid metabolic process
B	0009274	cellular_component	peptidoglycan-based cell wall
B	0016740	molecular_function	transferase activity
B	0016787	molecular_function	hydrolase activity
B	0045302	molecular_function	choloylglycine hydrolase activity
B	0047742	molecular_function	chenodeoxycholoyltaurine hydrolase activity
B	7770003	molecular_function	amino acid conjugated cholate hydrolase activity
B	7770004	molecular_function	L-serine conjugated cholate hydrolase activity
B	7770005	molecular_function	L-alanine conjugated cholate hydrolase activity
B	7770008	molecular_function	L-histidine conjugated cholate hydrolase activity
C	0005515	molecular_function	protein binding
C	0006629	biological_process	lipid metabolic process
C	0009274	cellular_component	peptidoglycan-based cell wall
C	0016740	molecular_function	transferase activity
C	0016787	molecular_function	hydrolase activity
C	0045302	molecular_function	choloylglycine hydrolase activity
C	0047742	molecular_function	chenodeoxycholoyltaurine hydrolase activity
C	7770003	molecular_function	amino acid conjugated cholate hydrolase activity
C	7770004	molecular_function	L-serine conjugated cholate hydrolase activity
C	7770005	molecular_function	L-alanine conjugated cholate hydrolase activity
C	7770008	molecular_function	L-histidine conjugated cholate hydrolase activity
D	0005515	molecular_function	protein binding
D	0006629	biological_process	lipid metabolic process
D	0009274	cellular_component	peptidoglycan-based cell wall
D	0016740	molecular_function	transferase activity
D	0016787	molecular_function	hydrolase activity
D	0045302	molecular_function	choloylglycine hydrolase activity
D	0047742	molecular_function	chenodeoxycholoyltaurine hydrolase activity
D	7770003	molecular_function	amino acid conjugated cholate hydrolase activity
D	7770004	molecular_function	L-serine conjugated cholate hydrolase activity
D	7770005	molecular_function	L-alanine conjugated cholate hydrolase activity
D	7770008	molecular_function	L-histidine conjugated cholate hydrolase activity
E	0005515	molecular_function	protein binding
E	0006629	biological_process	lipid metabolic process
E	0009274	cellular_component	peptidoglycan-based cell wall
E	0016740	molecular_function	transferase activity
E	0016787	molecular_function	hydrolase activity
E	0045302	molecular_function	choloylglycine hydrolase activity
E	0047742	molecular_function	chenodeoxycholoyltaurine hydrolase activity
E	7770003	molecular_function	amino acid conjugated cholate hydrolase activity
E	7770004	molecular_function	L-serine conjugated cholate hydrolase activity
E	7770005	molecular_function	L-alanine conjugated cholate hydrolase activity
E	7770008	molecular_function	L-histidine conjugated cholate hydrolase activity
F	0005515	molecular_function	protein binding
F	0006629	biological_process	lipid metabolic process
F	0009274	cellular_component	peptidoglycan-based cell wall
F	0016740	molecular_function	transferase activity
F	0016787	molecular_function	hydrolase activity
F	0045302	molecular_function	choloylglycine hydrolase activity
F	0047742	molecular_function	chenodeoxycholoyltaurine hydrolase activity
F	7770003	molecular_function	amino acid conjugated cholate hydrolase activity
F	7770004	molecular_function	L-serine conjugated cholate hydrolase activity
F	7770005	molecular_function	L-alanine conjugated cholate hydrolase activity
F	7770008	molecular_function	L-histidine conjugated cholate hydrolase activity
G	0005515	molecular_function	protein binding
G	0006629	biological_process	lipid metabolic process
G	0009274	cellular_component	peptidoglycan-based cell wall
G	0016740	molecular_function	transferase activity
G	0016787	molecular_function	hydrolase activity
G	0045302	molecular_function	choloylglycine hydrolase activity
G	0047742	molecular_function	chenodeoxycholoyltaurine hydrolase activity
G	7770003	molecular_function	amino acid conjugated cholate hydrolase activity
G	7770004	molecular_function	L-serine conjugated cholate hydrolase activity
G	7770005	molecular_function	L-alanine conjugated cholate hydrolase activity
G	7770008	molecular_function	L-histidine conjugated cholate hydrolase activity
H	0005515	molecular_function	protein binding
H	0006629	biological_process	lipid metabolic process
H	0009274	cellular_component	peptidoglycan-based cell wall
H	0016740	molecular_function	transferase activity
H	0016787	molecular_function	hydrolase activity
H	0045302	molecular_function	choloylglycine hydrolase activity
H	0047742	molecular_function	chenodeoxycholoyltaurine hydrolase activity
H	7770003	molecular_function	amino acid conjugated cholate hydrolase activity
H	7770004	molecular_function	L-serine conjugated cholate hydrolase activity
H	7770005	molecular_function	L-alanine conjugated cholate hydrolase activity
H	7770008	molecular_function	L-histidine conjugated cholate hydrolase activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	Active site: {"description":"Nucleophile; acyl-thioester intermediate","evidences":[{"source":"PubMed","id":"10831430","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	24
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P54965","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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