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8ESC

Structure of the Yeast NuA4 Histone Acetyltransferase Complex

Functional Information from GO Data
ChainGOidnamespacecontents
A0000011biological_processvacuole inheritance
A0000142cellular_componentcellular bud neck contractile ring
A0000785cellular_componentchromatin
A0000812cellular_componentSwr1 complex
A0005200molecular_functionstructural constituent of cytoskeleton
A0005515molecular_functionprotein binding
A0005524molecular_functionATP binding
A0005634cellular_componentnucleus
A0005737cellular_componentcytoplasm
A0005856cellular_componentcytoskeleton
A0005884cellular_componentactin filament
A0006281biological_processDNA repair
A0006338biological_processchromatin remodeling
A0006351biological_processDNA-templated transcription
A0006355biological_processregulation of DNA-templated transcription
A0006897biological_processendocytosis
A0009306biological_processprotein secretion
A0016787molecular_functionhydrolase activity
A0016887molecular_functionATP hydrolysis activity
A0030010biological_processestablishment of cell polarity
A0030476biological_processascospore wall assembly
A0030479cellular_componentactin cortical patch
A0031011cellular_componentIno80 complex
A0032432cellular_componentactin filament bundle
A0035267cellular_componentNuA4 histone acetyltransferase complex
A0042802molecular_functionidentical protein binding
A0043232cellular_componentintracellular non-membrane-bounded organelle
A1902404biological_processmitotic actomyosin contractile ring contraction
E0003674molecular_functionmolecular_function
E0003682molecular_functionchromatin binding
E0005515molecular_functionprotein binding
E0005634cellular_componentnucleus
E0006281biological_processDNA repair
E0006325biological_processchromatin organization
E0006351biological_processDNA-templated transcription
E0035267cellular_componentNuA4 histone acetyltransferase complex
E0065003biological_processprotein-containing complex assembly
P0000786cellular_componentnucleosome
P0004402molecular_functionhistone acetyltransferase activity
P0005515molecular_functionprotein binding
P0005634cellular_componentnucleus
P0006281biological_processDNA repair
P0006338biological_processchromatin remodeling
P0006351biological_processDNA-templated transcription
P0006357biological_processregulation of transcription by RNA polymerase II
P0016239biological_processpositive regulation of macroautophagy
P0032777cellular_componentpiccolo histone acetyltransferase complex
P0035267cellular_componentNuA4 histone acetyltransferase complex
R0000785cellular_componentchromatin
R0000812cellular_componentSwr1 complex
R0003682molecular_functionchromatin binding
R0005515molecular_functionprotein binding
R0005524molecular_functionATP binding
R0005634cellular_componentnucleus
R0006281biological_processDNA repair
R0006325biological_processchromatin organization
R0006338biological_processchromatin remodeling
R0006351biological_processDNA-templated transcription
R0006355biological_processregulation of DNA-templated transcription
R0006357biological_processregulation of transcription by RNA polymerase II
R0016514cellular_componentSWI/SNF complex
R0031011cellular_componentIno80 complex
R0035267cellular_componentNuA4 histone acetyltransferase complex
R0042393molecular_functionhistone binding
R0043232cellular_componentintracellular non-membrane-bounded organelle
R0051382biological_processkinetochore assembly
S0000122biological_processnegative regulation of transcription by RNA polymerase II
S0000785cellular_componentchromatin
S0000812cellular_componentSwr1 complex
S0003714molecular_functiontranscription corepressor activity
S0005515molecular_functionprotein binding
S0005634cellular_componentnucleus
S0005694cellular_componentchromosome
S0006281biological_processDNA repair
S0006325biological_processchromatin organization
S0006338biological_processchromatin remodeling
S0006351biological_processDNA-templated transcription
S0006355biological_processregulation of DNA-templated transcription
S0035267cellular_componentNuA4 histone acetyltransferase complex
S0051276biological_processchromosome organization
Z0000124cellular_componentSAGA complex
Z0004402molecular_functionhistone acetyltransferase activity
Z0004672molecular_functionprotein kinase activity
Z0005515molecular_functionprotein binding
Z0005634cellular_componentnucleus
Z0006281biological_processDNA repair
Z0006325biological_processchromatin organization
Z0006338biological_processchromatin remodeling
Z0006351biological_processDNA-templated transcription
Z0006355biological_processregulation of DNA-templated transcription
Z0006357biological_processregulation of transcription by RNA polymerase II
Z0035267cellular_componentNuA4 histone acetyltransferase complex
Z0045944biological_processpositive regulation of transcription by RNA polymerase II
Z0046695cellular_componentSLIK (SAGA-like) complex
Functional Information from PROSITE/UniProt
site_idPS00406
Number of Residues11
DetailsACTINS_1 Actins signature 1. YVGDEAQs.KRG
ChainResidueDetails
ATYR53-GLY63

site_idPS00432
Number of Residues9
DetailsACTINS_2 Actins signature 2. WISKqEYDE
ChainResidueDetails
ATRP356-GLU364

site_idPS01132
Number of Residues13
DetailsACTINS_ACT_LIKE Actins and actin-related proteins signature. LLTEApMNPksNR
ChainResidueDetails
ALEU104-ARG116
RLEU109-ARG121

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsMOD_RES: N-acetylserine => ECO:0007744|PubMed:22814378
ChainResidueDetails
SSER2

site_idSWS_FT_FI2
Number of Residues1
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:18407956
ChainResidueDetails
ETHR971
ZSER542

site_idSWS_FT_FI3
Number of Residues2
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0007744|PubMed:22106047
ChainResidueDetails
ALYS191

222624

PDB entries from 2024-07-17

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