8EP7

Crystal Structure of the Ketol-acid Reductoisomerase from Bacillus anthracis in complex with NADP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0004455	molecular_function	ketol-acid reductoisomerase activity
A	0005829	cellular_component	cytosol
A	0008652	biological_process	amino acid biosynthetic process
A	0009082	biological_process	branched-chain amino acid biosynthetic process
A	0009097	biological_process	isoleucine biosynthetic process
A	0009099	biological_process	valine biosynthetic process
A	0016491	molecular_function	oxidoreductase activity
A	0046872	molecular_function	metal ion binding
A	0050661	molecular_function	NADP binding
B	0000287	molecular_function	magnesium ion binding
B	0004455	molecular_function	ketol-acid reductoisomerase activity
B	0005829	cellular_component	cytosol
B	0008652	biological_process	amino acid biosynthetic process
B	0009082	biological_process	branched-chain amino acid biosynthetic process
B	0009097	biological_process	isoleucine biosynthetic process
B	0009099	biological_process	valine biosynthetic process
B	0016491	molecular_function	oxidoreductase activity
B	0046872	molecular_function	metal ion binding
B	0050661	molecular_function	NADP binding
C	0000287	molecular_function	magnesium ion binding
C	0004455	molecular_function	ketol-acid reductoisomerase activity
C	0005829	cellular_component	cytosol
C	0008652	biological_process	amino acid biosynthetic process
C	0009082	biological_process	branched-chain amino acid biosynthetic process
C	0009097	biological_process	isoleucine biosynthetic process
C	0009099	biological_process	valine biosynthetic process
C	0016491	molecular_function	oxidoreductase activity
C	0046872	molecular_function	metal ion binding
C	0050661	molecular_function	NADP binding

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	ACT_SITE: ACT_SITE => ECO:0000255|HAMAP-Rule:MF_00435

Chain	Residue	Details
A	HIS106
B	HIS106
C	HIS106

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site_id	SWS_FT_FI2
Number of Residues	30
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00435

Chain	Residue	Details
A	TYR24
A	ARG47
A	SER51
A	ASP81
A	GLY132
A	ASP189
A	GLU193
A	GLU225
A	GLU229
A	SER250
B	TYR24
B	ARG47
B	SER51
B	ASP81
B	GLY132
B	ASP189
B	GLU193
B	GLU225
B	GLU229
B	SER250
C	TYR24
C	ARG47
C	SER51
C	ASP81
C	GLY132
C	ASP189
C	GLU193
C	GLU225
C	GLU229
C	SER250

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