8EOR
Liver carboxylesterase 1
Functional Information from PROSITE/UniProt
| site_id | PS00122 |
| Number of Residues | 16 |
| Details | CARBOXYLESTERASE_B_1 Carboxylesterases type-B serine active site. FGGnpgsVtIfGeSAG |
| Chain | Residue | Details |
| A | PHE208-GLY223 |
| site_id | PS00941 |
| Number of Residues | 11 |
| Details | CARBOXYLESTERASE_B_2 Carboxylesterases type-B signature 2. EDCLYLNIYtP |
| Chain | Residue | Details |
| A | GLU114-PRO124 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | ACT_SITE: Acyl-ester intermediate => ECO:0000255|PROSITE-ProRule:PRU10039, ECO:0000269|PubMed:12022871 |
| Chain | Residue | Details |
| A | SER221 | |
| B | SER221 | |
| C | SER221 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | ACT_SITE: Charge relay system => ECO:0000269|PubMed:12022871 |
| Chain | Residue | Details |
| A | GLU354 | |
| A | HIS468 | |
| B | GLU354 | |
| B | HIS468 | |
| C | GLU354 | |
| C | HIS468 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:24275569 |
| Chain | Residue | Details |
| A | SER380 | |
| B | SER380 | |
| C | SER380 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:12022871 |
| Chain | Residue | Details |
| A | ASN79 | |
| B | ASN79 | |
| C | ASN79 |
