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8EMA

mouse full length B cell receptor

Functional Information from GO Data
ChainGOidnamespacecontents
A0000165biological_processMAPK cascade
A0002344biological_processB cell affinity maturation
A0002455biological_processhumoral immune response mediated by circulating immunoglobulin
A0002637biological_processregulation of immunoglobulin production
A0003823molecular_functionantigen binding
A0004888molecular_functiontransmembrane signaling receptor activity
A0005515molecular_functionprotein binding
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0005737cellular_componentcytoplasm
A0005886cellular_componentplasma membrane
A0006958biological_processcomplement activation, classical pathway
A0009897cellular_componentexternal side of plasma membrane
A0009986cellular_componentcell surface
A0016020cellular_componentmembrane
A0016064biological_processimmunoglobulin mediated immune response
A0019731biological_processantibacterial humoral response
A0019815cellular_componentB cell receptor complex
A0019882biological_processantigen processing and presentation
A0022604biological_processregulation of cell morphogenesis
A0030890biological_processpositive regulation of B cell proliferation
A0034987molecular_functionimmunoglobulin receptor binding
A0042100biological_processB cell proliferation
A0042113biological_processB cell activation
A0042571cellular_componentimmunoglobulin complex, circulating
A0042802molecular_functionidentical protein binding
A0043410biological_processpositive regulation of MAPK cascade
A0045022biological_processearly endosome to late endosome transport
A0045807biological_processpositive regulation of endocytosis
A0048471cellular_componentperinuclear region of cytoplasm
A0050731biological_processpositive regulation of peptidyl-tyrosine phosphorylation
A0050778biological_processpositive regulation of immune response
A0050829biological_processdefense response to Gram-negative bacterium
A0050853biological_processB cell receptor signaling pathway
A0050871biological_processpositive regulation of B cell activation
B0000165biological_processMAPK cascade
B0002344biological_processB cell affinity maturation
B0002455biological_processhumoral immune response mediated by circulating immunoglobulin
B0002637biological_processregulation of immunoglobulin production
B0003823molecular_functionantigen binding
B0004888molecular_functiontransmembrane signaling receptor activity
B0005515molecular_functionprotein binding
B0005576cellular_componentextracellular region
B0005615cellular_componentextracellular space
B0005737cellular_componentcytoplasm
B0005886cellular_componentplasma membrane
B0006958biological_processcomplement activation, classical pathway
B0009897cellular_componentexternal side of plasma membrane
B0009986cellular_componentcell surface
B0016020cellular_componentmembrane
B0016064biological_processimmunoglobulin mediated immune response
B0019731biological_processantibacterial humoral response
B0019815cellular_componentB cell receptor complex
B0019882biological_processantigen processing and presentation
B0022604biological_processregulation of cell morphogenesis
B0030890biological_processpositive regulation of B cell proliferation
B0034987molecular_functionimmunoglobulin receptor binding
B0042100biological_processB cell proliferation
B0042113biological_processB cell activation
B0042571cellular_componentimmunoglobulin complex, circulating
B0042802molecular_functionidentical protein binding
B0043410biological_processpositive regulation of MAPK cascade
B0045022biological_processearly endosome to late endosome transport
B0045807biological_processpositive regulation of endocytosis
B0048471cellular_componentperinuclear region of cytoplasm
B0050731biological_processpositive regulation of peptidyl-tyrosine phosphorylation
B0050778biological_processpositive regulation of immune response
B0050829biological_processdefense response to Gram-negative bacterium
B0050853biological_processB cell receptor signaling pathway
B0050871biological_processpositive regulation of B cell activation
C0004746molecular_functionriboflavin synthase activity
C0005829cellular_componentcytosol
C0008218biological_processbioluminescence
C0009231biological_processriboflavin biosynthetic process
C0019815cellular_componentB cell receptor complex
C0050853biological_processB cell receptor signaling pathway
D0004888molecular_functiontransmembrane signaling receptor activity
D0007166biological_processcell surface receptor signaling pathway
D0016020cellular_componentmembrane
D0019815cellular_componentB cell receptor complex
D0050853biological_processB cell receptor signaling pathway
Functional Information from PROSITE/UniProt
site_idPS00290
Number of Residues7
DetailsIG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YTCRVDH
ChainResidueDetails
APHE442-HIS448
ATYR552-HIS558
ATYR336-HIS342
RTYR213-HIS219

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues132
DetailsTOPO_DOM: Extracellular => ECO:0000255
ChainResidueDetails
DVAL26-ASP158
BASN236

site_idSWS_FT_FI2
Number of Residues21
DetailsTRANSMEM: Helical => ECO:0000255
ChainResidueDetails
DGLY159-LEU180
AASN350
AASN382
AASN420
BASN185
BASN350
BASN382
BASN420

site_idSWS_FT_FI3
Number of Residues47
DetailsTOPO_DOM: Cytoplasmic => ECO:0000255
ChainResidueDetails
DASP181-GLU228
CASN68

site_idSWS_FT_FI4
Number of Residues2
DetailsMOD_RES: Phosphotyrosine; by SRC-type Tyr-kinases => ECO:0000255|PROSITE-ProRule:PRU00379, ECO:0000269|PubMed:7592958
ChainResidueDetails
DTYR195
DTYR206

site_idSWS_FT_FI5
Number of Residues3
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255
ChainResidueDetails
DASN68
DASN99
DASN130

219869

PDB entries from 2024-05-15

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