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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

8EFY

Structure of double homo-hexameric AAA+ ATPase RuvB motors

Functional Information from GO Data
ChainGOidnamespacecontents
A0000166molecular_functionnucleotide binding
A0000400molecular_functionfour-way junction DNA binding
A0003677molecular_functionDNA binding
A0005524molecular_functionATP binding
A0005737cellular_componentcytoplasm
A0006281biological_processDNA repair
A0006310biological_processDNA recombination
A0006974biological_processDNA damage response
A0009378molecular_functionfour-way junction helicase activity
A0016787molecular_functionhydrolase activity
A0016887molecular_functionATP hydrolysis activity
A0048476cellular_componentHolliday junction resolvase complex
B0000166molecular_functionnucleotide binding
B0000400molecular_functionfour-way junction DNA binding
B0003677molecular_functionDNA binding
B0005524molecular_functionATP binding
B0005737cellular_componentcytoplasm
B0006281biological_processDNA repair
B0006310biological_processDNA recombination
B0006974biological_processDNA damage response
B0009378molecular_functionfour-way junction helicase activity
B0016787molecular_functionhydrolase activity
B0016887molecular_functionATP hydrolysis activity
B0048476cellular_componentHolliday junction resolvase complex
C0000166molecular_functionnucleotide binding
C0000400molecular_functionfour-way junction DNA binding
C0003677molecular_functionDNA binding
C0005524molecular_functionATP binding
C0005737cellular_componentcytoplasm
C0006281biological_processDNA repair
C0006310biological_processDNA recombination
C0006974biological_processDNA damage response
C0009378molecular_functionfour-way junction helicase activity
C0016787molecular_functionhydrolase activity
C0016887molecular_functionATP hydrolysis activity
C0048476cellular_componentHolliday junction resolvase complex
D0000166molecular_functionnucleotide binding
D0000400molecular_functionfour-way junction DNA binding
D0003677molecular_functionDNA binding
D0005524molecular_functionATP binding
D0005737cellular_componentcytoplasm
D0006281biological_processDNA repair
D0006310biological_processDNA recombination
D0006974biological_processDNA damage response
D0009378molecular_functionfour-way junction helicase activity
D0016787molecular_functionhydrolase activity
D0016887molecular_functionATP hydrolysis activity
D0048476cellular_componentHolliday junction resolvase complex
E0000166molecular_functionnucleotide binding
E0000400molecular_functionfour-way junction DNA binding
E0003677molecular_functionDNA binding
E0005524molecular_functionATP binding
E0005737cellular_componentcytoplasm
E0006281biological_processDNA repair
E0006310biological_processDNA recombination
E0006974biological_processDNA damage response
E0009378molecular_functionfour-way junction helicase activity
E0016787molecular_functionhydrolase activity
E0016887molecular_functionATP hydrolysis activity
E0048476cellular_componentHolliday junction resolvase complex
F0000166molecular_functionnucleotide binding
F0000400molecular_functionfour-way junction DNA binding
F0003677molecular_functionDNA binding
F0005524molecular_functionATP binding
F0005737cellular_componentcytoplasm
F0006281biological_processDNA repair
F0006310biological_processDNA recombination
F0006974biological_processDNA damage response
F0009378molecular_functionfour-way junction helicase activity
F0016787molecular_functionhydrolase activity
F0016887molecular_functionATP hydrolysis activity
F0048476cellular_componentHolliday junction resolvase complex
I0000166molecular_functionnucleotide binding
I0000400molecular_functionfour-way junction DNA binding
I0003677molecular_functionDNA binding
I0005524molecular_functionATP binding
I0005737cellular_componentcytoplasm
I0006281biological_processDNA repair
I0006310biological_processDNA recombination
I0006974biological_processDNA damage response
I0009378molecular_functionfour-way junction helicase activity
I0016787molecular_functionhydrolase activity
I0016887molecular_functionATP hydrolysis activity
I0048476cellular_componentHolliday junction resolvase complex
J0000166molecular_functionnucleotide binding
J0000400molecular_functionfour-way junction DNA binding
J0003677molecular_functionDNA binding
J0005524molecular_functionATP binding
J0005737cellular_componentcytoplasm
J0006281biological_processDNA repair
J0006310biological_processDNA recombination
J0006974biological_processDNA damage response
J0009378molecular_functionfour-way junction helicase activity
J0016787molecular_functionhydrolase activity
J0016887molecular_functionATP hydrolysis activity
J0048476cellular_componentHolliday junction resolvase complex
K0000166molecular_functionnucleotide binding
K0000400molecular_functionfour-way junction DNA binding
K0003677molecular_functionDNA binding
K0005524molecular_functionATP binding
K0005737cellular_componentcytoplasm
K0006281biological_processDNA repair
K0006310biological_processDNA recombination
K0006974biological_processDNA damage response
K0009378molecular_functionfour-way junction helicase activity
K0016787molecular_functionhydrolase activity
K0016887molecular_functionATP hydrolysis activity
K0048476cellular_componentHolliday junction resolvase complex
L0000166molecular_functionnucleotide binding
L0000400molecular_functionfour-way junction DNA binding
L0003677molecular_functionDNA binding
L0005524molecular_functionATP binding
L0005737cellular_componentcytoplasm
L0006281biological_processDNA repair
L0006310biological_processDNA recombination
L0006974biological_processDNA damage response
L0009378molecular_functionfour-way junction helicase activity
L0016787molecular_functionhydrolase activity
L0016887molecular_functionATP hydrolysis activity
L0048476cellular_componentHolliday junction resolvase complex
M0000166molecular_functionnucleotide binding
M0000400molecular_functionfour-way junction DNA binding
M0003677molecular_functionDNA binding
M0005524molecular_functionATP binding
M0005737cellular_componentcytoplasm
M0006281biological_processDNA repair
M0006310biological_processDNA recombination
M0006974biological_processDNA damage response
M0009378molecular_functionfour-way junction helicase activity
M0016787molecular_functionhydrolase activity
M0016887molecular_functionATP hydrolysis activity
M0048476cellular_componentHolliday junction resolvase complex
N0000166molecular_functionnucleotide binding
N0000400molecular_functionfour-way junction DNA binding
N0003677molecular_functionDNA binding
N0005524molecular_functionATP binding
N0005737cellular_componentcytoplasm
N0006281biological_processDNA repair
N0006310biological_processDNA recombination
N0006974biological_processDNA damage response
N0009378molecular_functionfour-way junction helicase activity
N0016787molecular_functionhydrolase activity
N0016887molecular_functionATP hydrolysis activity
N0048476cellular_componentHolliday junction resolvase complex
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues840
DetailsRegion: {"description":"Small ATPAse domain (RuvB-S)","evidences":[{"source":"HAMAP-Rule","id":"MF_00016","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"11171970","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails
site_idSWS_FT_FI2
Number of Residues12
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"11171970","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12408833","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1HQC","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"1IXS","evidenceCode":"ECO:0000312"}]}
ChainResidueDetails
site_idSWS_FT_FI3
Number of Residues12
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"11171970","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1HQC","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"1IXS","evidenceCode":"ECO:0000312"}]}
ChainResidueDetails
site_idSWS_FT_FI4
Number of Residues12
DetailsBinding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00016","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"12408833","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1IXR","evidenceCode":"ECO:0000312"}]}
ChainResidueDetails
site_idSWS_FT_FI5
Number of Residues24
DetailsBinding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00016","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"12408833","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1IXR","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"1IXS","evidenceCode":"ECO:0000312"}]}
ChainResidueDetails
site_idSWS_FT_FI6
Number of Residues36
DetailsBinding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00016","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails
site_idSWS_FT_FI7
Number of Residues24
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"12408833","evidenceCode":"ECO:0000305"}]}
ChainResidueDetails
site_idSWS_FT_FI8
Number of Residues12
DetailsBinding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00016","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"11171970","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"12408833","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1HQC","evidenceCode":"ECO:0000312"},{"source":"PDB","id":"1IXS","evidenceCode":"ECO:0000312"}]}
ChainResidueDetails
site_idSWS_FT_FI9
Number of Residues12
DetailsBinding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00016","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"12408833","evidenceCode":"ECO:0000305"}]}
ChainResidueDetails
Catalytic Information from CSA
site_idMCSA1
Number of Residues5
DetailsM-CSA 780
ChainResidueDetails
ALYS51
ATHR52
AASP97
ATHR146electrostatic stabiliser
AARG205electrostatic stabiliser
site_idMCSA10
Number of Residues5
DetailsM-CSA 780
ChainResidueDetails
LLYS51
LTHR52
LASP97
LTHR146electrostatic stabiliser
LARG205electrostatic stabiliser
site_idMCSA11
Number of Residues5
DetailsM-CSA 780
ChainResidueDetails
MLYS51
MTHR52
MASP97
MTHR146electrostatic stabiliser
MARG205electrostatic stabiliser
site_idMCSA12
Number of Residues5
DetailsM-CSA 780
ChainResidueDetails
NLYS51
NTHR52
NASP97
NTHR146electrostatic stabiliser
NARG205electrostatic stabiliser
site_idMCSA2
Number of Residues5
DetailsM-CSA 780
ChainResidueDetails
BLYS51
BTHR52
BASP97
BTHR146electrostatic stabiliser
BARG205electrostatic stabiliser
site_idMCSA3
Number of Residues5
DetailsM-CSA 780
ChainResidueDetails
CLYS51
CTHR52
CASP97
CTHR146electrostatic stabiliser
CARG205electrostatic stabiliser
site_idMCSA4
Number of Residues5
DetailsM-CSA 780
ChainResidueDetails
DLYS51
DTHR52
DASP97
DTHR146electrostatic stabiliser
DARG205electrostatic stabiliser
site_idMCSA5
Number of Residues5
DetailsM-CSA 780
ChainResidueDetails
ELYS51
ETHR52
EASP97
ETHR146electrostatic stabiliser
EARG205electrostatic stabiliser
site_idMCSA6
Number of Residues5
DetailsM-CSA 780
ChainResidueDetails
FLYS51
FTHR52
FASP97
FTHR146electrostatic stabiliser
FARG205electrostatic stabiliser
site_idMCSA7
Number of Residues5
DetailsM-CSA 780
ChainResidueDetails
ILYS51
ITHR52
IASP97
ITHR146electrostatic stabiliser
IARG205electrostatic stabiliser
site_idMCSA8
Number of Residues5
DetailsM-CSA 780
ChainResidueDetails
JLYS51
JTHR52
JASP97
JTHR146electrostatic stabiliser
JARG205electrostatic stabiliser
site_idMCSA9
Number of Residues5
DetailsM-CSA 780
ChainResidueDetails
KLYS51
KTHR52
KASP97
KTHR146electrostatic stabiliser
KARG205electrostatic stabiliser

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PDB entries from 2026-01-14

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