8EFY

Structure of double homo-hexameric AAA+ ATPase RuvB motors

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000400	molecular_function	four-way junction DNA binding
A	0003677	molecular_function	DNA binding
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0006281	biological_process	DNA repair
A	0006310	biological_process	DNA recombination
A	0009378	molecular_function	four-way junction helicase activity
A	0016787	molecular_function	hydrolase activity
A	0016887	molecular_function	ATP hydrolysis activity
A	0032508	biological_process	DNA duplex unwinding
A	0048476	cellular_component	Holliday junction resolvase complex
B	0000400	molecular_function	four-way junction DNA binding
B	0003677	molecular_function	DNA binding
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0006281	biological_process	DNA repair
B	0006310	biological_process	DNA recombination
B	0009378	molecular_function	four-way junction helicase activity
B	0016787	molecular_function	hydrolase activity
B	0016887	molecular_function	ATP hydrolysis activity
B	0032508	biological_process	DNA duplex unwinding
B	0048476	cellular_component	Holliday junction resolvase complex
C	0000400	molecular_function	four-way junction DNA binding
C	0003677	molecular_function	DNA binding
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0006281	biological_process	DNA repair
C	0006310	biological_process	DNA recombination
C	0009378	molecular_function	four-way junction helicase activity
C	0016787	molecular_function	hydrolase activity
C	0016887	molecular_function	ATP hydrolysis activity
C	0032508	biological_process	DNA duplex unwinding
C	0048476	cellular_component	Holliday junction resolvase complex
D	0000400	molecular_function	four-way junction DNA binding
D	0003677	molecular_function	DNA binding
D	0005524	molecular_function	ATP binding
D	0005737	cellular_component	cytoplasm
D	0006281	biological_process	DNA repair
D	0006310	biological_process	DNA recombination
D	0009378	molecular_function	four-way junction helicase activity
D	0016787	molecular_function	hydrolase activity
D	0016887	molecular_function	ATP hydrolysis activity
D	0032508	biological_process	DNA duplex unwinding
D	0048476	cellular_component	Holliday junction resolvase complex
E	0000400	molecular_function	four-way junction DNA binding
E	0003677	molecular_function	DNA binding
E	0005524	molecular_function	ATP binding
E	0005737	cellular_component	cytoplasm
E	0006281	biological_process	DNA repair
E	0006310	biological_process	DNA recombination
E	0009378	molecular_function	four-way junction helicase activity
E	0016787	molecular_function	hydrolase activity
E	0016887	molecular_function	ATP hydrolysis activity
E	0032508	biological_process	DNA duplex unwinding
E	0048476	cellular_component	Holliday junction resolvase complex
F	0000400	molecular_function	four-way junction DNA binding
F	0003677	molecular_function	DNA binding
F	0005524	molecular_function	ATP binding
F	0005737	cellular_component	cytoplasm
F	0006281	biological_process	DNA repair
F	0006310	biological_process	DNA recombination
F	0009378	molecular_function	four-way junction helicase activity
F	0016787	molecular_function	hydrolase activity
F	0016887	molecular_function	ATP hydrolysis activity
F	0032508	biological_process	DNA duplex unwinding
F	0048476	cellular_component	Holliday junction resolvase complex
I	0000400	molecular_function	four-way junction DNA binding
I	0003677	molecular_function	DNA binding
I	0005524	molecular_function	ATP binding
I	0005737	cellular_component	cytoplasm
I	0006281	biological_process	DNA repair
I	0006310	biological_process	DNA recombination
I	0009378	molecular_function	four-way junction helicase activity
I	0016787	molecular_function	hydrolase activity
I	0016887	molecular_function	ATP hydrolysis activity
I	0032508	biological_process	DNA duplex unwinding
I	0048476	cellular_component	Holliday junction resolvase complex
J	0000400	molecular_function	four-way junction DNA binding
J	0003677	molecular_function	DNA binding
J	0005524	molecular_function	ATP binding
J	0005737	cellular_component	cytoplasm
J	0006281	biological_process	DNA repair
J	0006310	biological_process	DNA recombination
J	0009378	molecular_function	four-way junction helicase activity
J	0016787	molecular_function	hydrolase activity
J	0016887	molecular_function	ATP hydrolysis activity
J	0032508	biological_process	DNA duplex unwinding
J	0048476	cellular_component	Holliday junction resolvase complex
K	0000400	molecular_function	four-way junction DNA binding
K	0003677	molecular_function	DNA binding
K	0005524	molecular_function	ATP binding
K	0005737	cellular_component	cytoplasm
K	0006281	biological_process	DNA repair
K	0006310	biological_process	DNA recombination
K	0009378	molecular_function	four-way junction helicase activity
K	0016787	molecular_function	hydrolase activity
K	0016887	molecular_function	ATP hydrolysis activity
K	0032508	biological_process	DNA duplex unwinding
K	0048476	cellular_component	Holliday junction resolvase complex
L	0000400	molecular_function	four-way junction DNA binding
L	0003677	molecular_function	DNA binding
L	0005524	molecular_function	ATP binding
L	0005737	cellular_component	cytoplasm
L	0006281	biological_process	DNA repair
L	0006310	biological_process	DNA recombination
L	0009378	molecular_function	four-way junction helicase activity
L	0016787	molecular_function	hydrolase activity
L	0016887	molecular_function	ATP hydrolysis activity
L	0032508	biological_process	DNA duplex unwinding
L	0048476	cellular_component	Holliday junction resolvase complex
M	0000400	molecular_function	four-way junction DNA binding
M	0003677	molecular_function	DNA binding
M	0005524	molecular_function	ATP binding
M	0005737	cellular_component	cytoplasm
M	0006281	biological_process	DNA repair
M	0006310	biological_process	DNA recombination
M	0009378	molecular_function	four-way junction helicase activity
M	0016787	molecular_function	hydrolase activity
M	0016887	molecular_function	ATP hydrolysis activity
M	0032508	biological_process	DNA duplex unwinding
M	0048476	cellular_component	Holliday junction resolvase complex
N	0000400	molecular_function	four-way junction DNA binding
N	0003677	molecular_function	DNA binding
N	0005524	molecular_function	ATP binding
N	0005737	cellular_component	cytoplasm
N	0006281	biological_process	DNA repair
N	0006310	biological_process	DNA recombination
N	0009378	molecular_function	four-way junction helicase activity
N	0016787	molecular_function	hydrolase activity
N	0016887	molecular_function	ATP hydrolysis activity
N	0032508	biological_process	DNA duplex unwinding
N	0048476	cellular_component	Holliday junction resolvase complex

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	BINDING: BINDING => ECO:0000269|PubMed:11171970, ECO:0000269|PubMed:12408833, ECO:0000312|PDB:1HQC, ECO:0000312|PDB:1IXS

Chain	Residue	Details
A	TYR14
B	TYR14
C	TYR14
D	TYR14
E	TYR14
F	TYR14
I	TYR14
J	TYR14
K	TYR14
L	TYR14
M	TYR14
N	TYR14

---

site_id	SWS_FT_FI2
Number of Residues	12
Details	BINDING: BINDING => ECO:0000269|PubMed:11171970, ECO:0000312|PDB:1HQC, ECO:0000312|PDB:1IXS

Chain	Residue	Details
A	ILE15
B	ILE15
C	ILE15
D	ILE15
E	ILE15
F	ILE15
I	ILE15
J	ILE15
K	ILE15
L	ILE15
M	ILE15
N	ILE15

---

site_id	SWS_FT_FI3
Number of Residues	12
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00016, ECO:0000269|PubMed:12408833, ECO:0000312|PDB:1IXR

Chain	Residue	Details
A	GLY48
B	GLY48
C	GLY48
D	GLY48
E	GLY48
F	GLY48
I	GLY48
J	GLY48
K	GLY48
L	GLY48
M	GLY48
N	GLY48

---

site_id	SWS_FT_FI4
Number of Residues	24
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00016, ECO:0000269|PubMed:12408833, ECO:0000312|PDB:1IXR, ECO:0000312|PDB:1IXS

Chain	Residue	Details
A	LYS51
A	THR53
B	LYS51
B	THR53
C	LYS51
C	THR53
D	LYS51
D	THR53
E	LYS51
E	THR53
F	LYS51
F	THR53
I	LYS51
I	THR53
J	LYS51
J	THR53
K	LYS51
K	THR53
L	LYS51
L	THR53
M	LYS51
M	THR53
N	LYS51
N	THR53

---

site_id	SWS_FT_FI5
Number of Residues	36
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00016

Chain	Residue	Details
A	THR52
A	ARG297
A	ARG302
B	THR52
B	ARG297
B	ARG302
C	THR52
C	ARG297
C	ARG302
D	THR52
D	ARG297
D	ARG302
E	THR52
E	ARG297
E	ARG302
F	THR52
F	ARG297
F	ARG302
I	THR52
I	ARG297
I	ARG302
J	THR52
J	ARG297
J	ARG302
K	THR52
K	ARG297
K	ARG302
L	THR52
L	ARG297
L	ARG302
M	THR52
M	ARG297
M	ARG302
N	THR52
N	ARG297
N	ARG302

---

site_id	SWS_FT_FI6
Number of Residues	24
Details	BINDING: BINDING => ECO:0000305|PubMed:12408833

Chain	Residue	Details
A	ASP97
A	THR146
B	ASP97
B	THR146
C	ASP97
C	THR146
D	ASP97
D	THR146
E	ASP97
E	THR146
F	ASP97
F	THR146
I	ASP97
I	THR146
J	ASP97
J	THR146
K	ASP97
K	THR146
L	ASP97
L	THR146
M	ASP97
M	THR146
N	ASP97
N	THR146

---

site_id	SWS_FT_FI7
Number of Residues	12
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00016, ECO:0000269|PubMed:11171970, ECO:0000269|PubMed:12408833, ECO:0000312|PDB:1HQC, ECO:0000312|PDB:1IXS

Chain	Residue	Details
A	TYR168
B	TYR168
C	TYR168
D	TYR168
E	TYR168
F	TYR168
I	TYR168
J	TYR168
K	TYR168
L	TYR168
M	TYR168
N	TYR168

---

site_id	SWS_FT_FI8
Number of Residues	12
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00016, ECO:0000305|PubMed:12408833

Chain	Residue	Details
A	ARG205
B	ARG205
C	ARG205
D	ARG205
E	ARG205
F	ARG205
I	ARG205
J	ARG205
K	ARG205
L	ARG205
M	ARG205
N	ARG205

---

Catalytic Information from CSA

site_id	MCSA1
Number of Residues	5
Details	M-CSA 780

Chain	Residue	Details
A	LYS51
A	THR52
A	ASP97
A	THR146	electrostatic stabiliser
A	ARG205	electrostatic stabiliser

---

site_id	MCSA2
Number of Residues	5
Details	M-CSA 780

Chain	Residue	Details
B	LYS51
B	THR52
B	ASP97
B	THR146	electrostatic stabiliser
B	ARG205	electrostatic stabiliser

---

site_id	MCSA3
Number of Residues	5
Details	M-CSA 780

Chain	Residue	Details
C	LYS51
C	THR52
C	ASP97
C	THR146	electrostatic stabiliser
C	ARG205	electrostatic stabiliser

---

site_id	MCSA4
Number of Residues	5
Details	M-CSA 780

Chain	Residue	Details
D	LYS51
D	THR52
D	ASP97
D	THR146	electrostatic stabiliser
D	ARG205	electrostatic stabiliser

---

site_id	MCSA5
Number of Residues	5
Details	M-CSA 780

Chain	Residue	Details
E	LYS51
E	THR52
E	ASP97
E	THR146	electrostatic stabiliser
E	ARG205	electrostatic stabiliser

---

site_id	MCSA6
Number of Residues	5
Details	M-CSA 780

Chain	Residue	Details
F	LYS51
F	THR52
F	ASP97
F	THR146	electrostatic stabiliser
F	ARG205	electrostatic stabiliser

---

site_id	MCSA7
Number of Residues	5
Details	M-CSA 780

Chain	Residue	Details
I	LYS51
I	THR52
I	ASP97
I	THR146	electrostatic stabiliser
I	ARG205	electrostatic stabiliser

---

site_id	MCSA8
Number of Residues	5
Details	M-CSA 780

Chain	Residue	Details
J	LYS51
J	THR52
J	ASP97
J	THR146	electrostatic stabiliser
J	ARG205	electrostatic stabiliser

---

site_id	MCSA9
Number of Residues	5
Details	M-CSA 780

Chain	Residue	Details
K	LYS51
K	THR52
K	ASP97
K	THR146	electrostatic stabiliser
K	ARG205	electrostatic stabiliser

---

site_id	MCSA10
Number of Residues	5
Details	M-CSA 780

Chain	Residue	Details
L	LYS51
L	THR52
L	ASP97
L	THR146	electrostatic stabiliser
L	ARG205	electrostatic stabiliser

---

site_id	MCSA11
Number of Residues	5
Details	M-CSA 780

Chain	Residue	Details
M	LYS51
M	THR52
M	ASP97
M	THR146	electrostatic stabiliser
M	ARG205	electrostatic stabiliser

---

site_id	MCSA12
Number of Residues	5
Details	M-CSA 780

Chain	Residue	Details
N	LYS51
N	THR52
N	ASP97
N	THR146	electrostatic stabiliser
N	ARG205	electrostatic stabiliser

---