8EEU

Venezuelan equine encephalitis virus-like particle in complex with Fab SKT05

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
A	0004252	molecular_function	serine-type endopeptidase activity
A	0005198	molecular_function	structural molecule activity
A	0006508	biological_process	proteolysis
A	0008233	molecular_function	peptidase activity
A	0008236	molecular_function	serine-type peptidase activity
A	0016787	molecular_function	hydrolase activity
A	0019028	cellular_component	viral capsid
A	0019031	cellular_component	viral envelope
A	0019058	biological_process	viral life cycle
A	0019062	biological_process	virion attachment to host cell
A	0020002	cellular_component	host cell plasma membrane
A	0030430	cellular_component	host cell cytoplasm
A	0039619	cellular_component	T=4 icosahedral viral capsid
A	0039654	biological_process	fusion of virus membrane with host endosome membrane
A	0039657	biological_process	symbiont-mediated suppression of host gene expression
A	0039663	biological_process	membrane fusion involved in viral entry into host cell
A	0039722	biological_process	symbiont-mediated suppression of host toll-like receptor signaling pathway
A	0042025	cellular_component	host cell nucleus
A	0044423	cellular_component	virion component
A	0046718	biological_process	symbiont entry into host cell
A	0055036	cellular_component	virion membrane
A	0075509	biological_process	endocytosis involved in viral entry into host cell
A	0075512	biological_process	clathrin-dependent endocytosis of virus by host cell
A	0098670	biological_process	entry receptor-mediated virion attachment to host cell
B	0003723	molecular_function	RNA binding
B	0004252	molecular_function	serine-type endopeptidase activity
B	0005198	molecular_function	structural molecule activity
B	0006508	biological_process	proteolysis
B	0008233	molecular_function	peptidase activity
B	0008236	molecular_function	serine-type peptidase activity
B	0016787	molecular_function	hydrolase activity
B	0019028	cellular_component	viral capsid
B	0019031	cellular_component	viral envelope
B	0019058	biological_process	viral life cycle
B	0019062	biological_process	virion attachment to host cell
B	0020002	cellular_component	host cell plasma membrane
B	0030430	cellular_component	host cell cytoplasm
B	0039619	cellular_component	T=4 icosahedral viral capsid
B	0039654	biological_process	fusion of virus membrane with host endosome membrane
B	0039657	biological_process	symbiont-mediated suppression of host gene expression
B	0039663	biological_process	membrane fusion involved in viral entry into host cell
B	0039722	biological_process	symbiont-mediated suppression of host toll-like receptor signaling pathway
B	0042025	cellular_component	host cell nucleus
B	0044423	cellular_component	virion component
B	0046718	biological_process	symbiont entry into host cell
B	0055036	cellular_component	virion membrane
B	0075509	biological_process	endocytosis involved in viral entry into host cell
B	0075512	biological_process	clathrin-dependent endocytosis of virus by host cell
B	0098670	biological_process	entry receptor-mediated virion attachment to host cell
C	0003723	molecular_function	RNA binding
C	0004252	molecular_function	serine-type endopeptidase activity
C	0005198	molecular_function	structural molecule activity
C	0006508	biological_process	proteolysis
C	0008233	molecular_function	peptidase activity
C	0008236	molecular_function	serine-type peptidase activity
C	0016787	molecular_function	hydrolase activity
C	0019028	cellular_component	viral capsid
C	0019031	cellular_component	viral envelope
C	0019058	biological_process	viral life cycle
C	0019062	biological_process	virion attachment to host cell
C	0020002	cellular_component	host cell plasma membrane
C	0030430	cellular_component	host cell cytoplasm
C	0039619	cellular_component	T=4 icosahedral viral capsid
C	0039654	biological_process	fusion of virus membrane with host endosome membrane
C	0039657	biological_process	symbiont-mediated suppression of host gene expression
C	0039663	biological_process	membrane fusion involved in viral entry into host cell
C	0039722	biological_process	symbiont-mediated suppression of host toll-like receptor signaling pathway
C	0042025	cellular_component	host cell nucleus
C	0044423	cellular_component	virion component
C	0046718	biological_process	symbiont entry into host cell
C	0055036	cellular_component	virion membrane
C	0075509	biological_process	endocytosis involved in viral entry into host cell
C	0075512	biological_process	clathrin-dependent endocytosis of virus by host cell
C	0098670	biological_process	entry receptor-mediated virion attachment to host cell
D	0003723	molecular_function	RNA binding
D	0004252	molecular_function	serine-type endopeptidase activity
D	0005198	molecular_function	structural molecule activity
D	0006508	biological_process	proteolysis
D	0008233	molecular_function	peptidase activity
D	0008236	molecular_function	serine-type peptidase activity
D	0016787	molecular_function	hydrolase activity
D	0019028	cellular_component	viral capsid
D	0019031	cellular_component	viral envelope
D	0019058	biological_process	viral life cycle
D	0019062	biological_process	virion attachment to host cell
D	0020002	cellular_component	host cell plasma membrane
D	0030430	cellular_component	host cell cytoplasm
D	0039619	cellular_component	T=4 icosahedral viral capsid
D	0039654	biological_process	fusion of virus membrane with host endosome membrane
D	0039657	biological_process	symbiont-mediated suppression of host gene expression
D	0039663	biological_process	membrane fusion involved in viral entry into host cell
D	0039722	biological_process	symbiont-mediated suppression of host toll-like receptor signaling pathway
D	0042025	cellular_component	host cell nucleus
D	0044423	cellular_component	virion component
D	0046718	biological_process	symbiont entry into host cell
D	0055036	cellular_component	virion membrane
D	0075509	biological_process	endocytosis involved in viral entry into host cell
D	0075512	biological_process	clathrin-dependent endocytosis of virus by host cell
D	0098670	biological_process	entry receptor-mediated virion attachment to host cell
E	0003723	molecular_function	RNA binding
E	0004252	molecular_function	serine-type endopeptidase activity
E	0005198	molecular_function	structural molecule activity
E	0006508	biological_process	proteolysis
E	0008233	molecular_function	peptidase activity
E	0008236	molecular_function	serine-type peptidase activity
E	0016787	molecular_function	hydrolase activity
E	0019028	cellular_component	viral capsid
E	0019031	cellular_component	viral envelope
E	0019058	biological_process	viral life cycle
E	0019062	biological_process	virion attachment to host cell
E	0020002	cellular_component	host cell plasma membrane
E	0030430	cellular_component	host cell cytoplasm
E	0039619	cellular_component	T=4 icosahedral viral capsid
E	0039654	biological_process	fusion of virus membrane with host endosome membrane
E	0039657	biological_process	symbiont-mediated suppression of host gene expression
E	0039663	biological_process	membrane fusion involved in viral entry into host cell
E	0039722	biological_process	symbiont-mediated suppression of host toll-like receptor signaling pathway
E	0042025	cellular_component	host cell nucleus
E	0044423	cellular_component	virion component
E	0046718	biological_process	symbiont entry into host cell
E	0055036	cellular_component	virion membrane
E	0075509	biological_process	endocytosis involved in viral entry into host cell
E	0075512	biological_process	clathrin-dependent endocytosis of virus by host cell
E	0098670	biological_process	entry receptor-mediated virion attachment to host cell
F	0003723	molecular_function	RNA binding
F	0004252	molecular_function	serine-type endopeptidase activity
F	0005198	molecular_function	structural molecule activity
F	0006508	biological_process	proteolysis
F	0008233	molecular_function	peptidase activity
F	0008236	molecular_function	serine-type peptidase activity
F	0016787	molecular_function	hydrolase activity
F	0019028	cellular_component	viral capsid
F	0019031	cellular_component	viral envelope
F	0019058	biological_process	viral life cycle
F	0019062	biological_process	virion attachment to host cell
F	0020002	cellular_component	host cell plasma membrane
F	0030430	cellular_component	host cell cytoplasm
F	0039619	cellular_component	T=4 icosahedral viral capsid
F	0039654	biological_process	fusion of virus membrane with host endosome membrane
F	0039657	biological_process	symbiont-mediated suppression of host gene expression
F	0039663	biological_process	membrane fusion involved in viral entry into host cell
F	0039722	biological_process	symbiont-mediated suppression of host toll-like receptor signaling pathway
F	0042025	cellular_component	host cell nucleus
F	0044423	cellular_component	virion component
F	0046718	biological_process	symbiont entry into host cell
F	0055036	cellular_component	virion membrane
F	0075509	biological_process	endocytosis involved in viral entry into host cell
F	0075512	biological_process	clathrin-dependent endocytosis of virus by host cell
F	0098670	biological_process	entry receptor-mediated virion attachment to host cell

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YVCNVNH

Chain	Residue	Details
H	TYR194-HIS200
L	TYR192-HIS198

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	51
Details	Region: {"description":"E1 fusion peptide loop","evidences":[{"source":"UniProtKB","id":"Q8JUX5","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	9
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine; by host","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	18
Details	Site: {"description":"Interaction with host receptor LDLRAD3","evidences":[{"source":"PubMed","id":"34646020","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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