Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

8EAX

Octameric prenyltransferase domain of fusicoccadiene Synthase with C2 symmetry sans transiently associating cyclase domains

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004311	molecular_function	geranylgeranyl diphosphate synthase activity
A	0004659	molecular_function	prenyltransferase activity
A	0008299	biological_process	isoprenoid biosynthetic process
A	0016740	molecular_function	transferase activity
A	0016829	molecular_function	lyase activity
A	0043386	biological_process	mycotoxin biosynthetic process
A	0046165	biological_process	alcohol biosynthetic process
A	0046872	molecular_function	metal ion binding
B	0003824	molecular_function	catalytic activity
B	0004311	molecular_function	geranylgeranyl diphosphate synthase activity
B	0004659	molecular_function	prenyltransferase activity
B	0008299	biological_process	isoprenoid biosynthetic process
B	0016740	molecular_function	transferase activity
B	0016829	molecular_function	lyase activity
B	0043386	biological_process	mycotoxin biosynthetic process
B	0046165	biological_process	alcohol biosynthetic process
B	0046872	molecular_function	metal ion binding
C	0003824	molecular_function	catalytic activity
C	0004311	molecular_function	geranylgeranyl diphosphate synthase activity
C	0004659	molecular_function	prenyltransferase activity
C	0008299	biological_process	isoprenoid biosynthetic process
C	0016740	molecular_function	transferase activity
C	0016829	molecular_function	lyase activity
C	0043386	biological_process	mycotoxin biosynthetic process
C	0046165	biological_process	alcohol biosynthetic process
C	0046872	molecular_function	metal ion binding
D	0003824	molecular_function	catalytic activity
D	0004311	molecular_function	geranylgeranyl diphosphate synthase activity
D	0004659	molecular_function	prenyltransferase activity
D	0008299	biological_process	isoprenoid biosynthetic process
D	0016740	molecular_function	transferase activity
D	0016829	molecular_function	lyase activity
D	0043386	biological_process	mycotoxin biosynthetic process
D	0046165	biological_process	alcohol biosynthetic process
D	0046872	molecular_function	metal ion binding
E	0003824	molecular_function	catalytic activity
E	0004311	molecular_function	geranylgeranyl diphosphate synthase activity
E	0004659	molecular_function	prenyltransferase activity
E	0008299	biological_process	isoprenoid biosynthetic process
E	0016740	molecular_function	transferase activity
E	0016829	molecular_function	lyase activity
E	0043386	biological_process	mycotoxin biosynthetic process
E	0046165	biological_process	alcohol biosynthetic process
E	0046872	molecular_function	metal ion binding
F	0003824	molecular_function	catalytic activity
F	0004311	molecular_function	geranylgeranyl diphosphate synthase activity
F	0004659	molecular_function	prenyltransferase activity
F	0008299	biological_process	isoprenoid biosynthetic process
F	0016740	molecular_function	transferase activity
F	0016829	molecular_function	lyase activity
F	0043386	biological_process	mycotoxin biosynthetic process
F	0046165	biological_process	alcohol biosynthetic process
F	0046872	molecular_function	metal ion binding
G	0003824	molecular_function	catalytic activity
G	0004311	molecular_function	geranylgeranyl diphosphate synthase activity
G	0004659	molecular_function	prenyltransferase activity
G	0008299	biological_process	isoprenoid biosynthetic process
G	0016740	molecular_function	transferase activity
G	0016829	molecular_function	lyase activity
G	0043386	biological_process	mycotoxin biosynthetic process
G	0046165	biological_process	alcohol biosynthetic process
G	0046872	molecular_function	metal ion binding
H	0003824	molecular_function	catalytic activity
H	0004311	molecular_function	geranylgeranyl diphosphate synthase activity
H	0004659	molecular_function	prenyltransferase activity
H	0008299	biological_process	isoprenoid biosynthetic process
H	0016740	molecular_function	transferase activity
H	0016829	molecular_function	lyase activity
H	0043386	biological_process	mycotoxin biosynthetic process
H	0046165	biological_process	alcohol biosynthetic process
H	0046872	molecular_function	metal ion binding

Functional Information from PROSITE/UniProt

site_id	PS00444
Number of Residues	13
Details	POLYPRENYL_SYNTHASE_2 Polyprenyl synthases signature 2. LGrcFQIcDDYqN

Chain	Residue	Details
A	LEU597-ASN609

site_id	PS00723
Number of Residues	15
Details	POLYPRENYL_SYNTHASE_1 Polyprenyl synthases signature 1. LLlDDfq..DnsplRRG

Chain	Residue	Details
A	LEU471-GLY485

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	16
Details	BINDING: BINDING => ECO:0000250\|UniProtKB:Q40577

Chain	Residue	Details
A	ASP92
E	ASP96
F	ASP92
F	ASP96
G	ASP92
G	ASP96
H	ASP92
H	ASP96
A	ASP96
B	ASP92
B	ASP96
C	ASP92
C	ASP96
D	ASP92
D	ASP96
E	ASP92

site_id	SWS_FT_FI2
Number of Residues	104
Details	BINDING: BINDING => ECO:0000250\|UniProtKB:Q12051

Chain	Residue	Details
A	LYS435
A	GLN602
H	THR562
H	GLN602
H	ASN609
H	LYS619
H	LYS629
A	ASN609
A	LYS619
A	LYS629
B	LYS435
B	ARG438
B	HIS467
B	ASP474
B	ASP478
B	ARG483
A	ARG438
B	ARG484
B	LYS561
B	THR562
B	GLN602
B	ASN609
B	LYS619
B	LYS629
C	LYS435
C	ARG438
C	HIS467
A	HIS467
C	ASP474
C	ASP478
C	ARG483
C	ARG484
C	LYS561
C	THR562
C	GLN602
C	ASN609
C	LYS619
C	LYS629
A	ASP474
D	LYS435
D	ARG438
D	HIS467
D	ASP474
D	ASP478
D	ARG483
D	ARG484
D	LYS561
D	THR562
D	GLN602
A	ASP478
D	ASN609
D	LYS619
D	LYS629
E	LYS435
E	ARG438
E	HIS467
E	ASP474
E	ASP478
E	ARG483
E	ARG484
A	ARG483
E	LYS561
E	THR562
E	GLN602
E	ASN609
E	LYS619
E	LYS629
F	LYS435
F	ARG438
F	HIS467
F	ASP474
A	ARG484
F	ASP478
F	ARG483
F	ARG484
F	LYS561
F	THR562
F	GLN602
F	ASN609
F	LYS619
F	LYS629
G	LYS435
A	LYS561
G	ARG438
G	HIS467
G	ASP474
G	ASP478
G	ARG483
G	ARG484
G	LYS561
G	THR562
G	GLN602
G	ASN609
A	THR562
G	LYS619
G	LYS629
H	LYS435
H	ARG438
H	HIS467
H	ASP474
H	ASP478
H	ARG483
H	ARG484
H	LYS561

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)