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8EAT

Yeast VO missing subunits a, e, and f in complex with Vma12-22p

Functional Information from GO Data
ChainGOidnamespacecontents
A0005634cellular_componentnucleus
A0007035biological_processvacuolar acidification
A0051082molecular_functionunfolded protein binding
A0070072biological_processvacuolar proton-transporting V-type ATPase complex assembly
A1990871cellular_componentVma12-Vma22 assembly complex
B0003674molecular_functionmolecular_function
B0005783cellular_componentendoplasmic reticulum
B0005789cellular_componentendoplasmic reticulum membrane
B0007035biological_processvacuolar acidification
B0012505cellular_componentendomembrane system
B0016020cellular_componentmembrane
B0070072biological_processvacuolar proton-transporting V-type ATPase complex assembly
B1990871cellular_componentVma12-Vma22 assembly complex
c0000139cellular_componentGolgi membrane
c0000220cellular_componentvacuolar proton-transporting V-type ATPase, V0 domain
c0000329cellular_componentfungal-type vacuole membrane
c0005773cellular_componentvacuole
c0005774cellular_componentvacuolar membrane
c0007035biological_processvacuolar acidification
c0008553molecular_functionP-type proton-exporting transporter activity
c0015078molecular_functionproton transmembrane transporter activity
c0016020cellular_componentmembrane
c0016471cellular_componentvacuolar proton-transporting V-type ATPase complex
c0033176cellular_componentproton-transporting V-type ATPase complex
c0033177cellular_componentproton-transporting two-sector ATPase complex, proton-transporting domain
c0033179cellular_componentproton-transporting V-type ATPase, V0 domain
c0046961molecular_functionproton-transporting ATPase activity, rotational mechanism
c0048388biological_processendosomal lumen acidification
c0061795biological_processGolgi lumen acidification
c1902600biological_processproton transmembrane transport
d0000139cellular_componentGolgi membrane
d0000220cellular_componentvacuolar proton-transporting V-type ATPase, V0 domain
d0000329cellular_componentfungal-type vacuole membrane
d0005515molecular_functionprotein binding
d0005773cellular_componentvacuole
d0005774cellular_componentvacuolar membrane
d0007034biological_processvacuolar transport
d0007035biological_processvacuolar acidification
d0016020cellular_componentmembrane
d0016471cellular_componentvacuolar proton-transporting V-type ATPase complex
d0033176cellular_componentproton-transporting V-type ATPase complex
d0033179cellular_componentproton-transporting V-type ATPase, V0 domain
d0046961molecular_functionproton-transporting ATPase activity, rotational mechanism
d0048388biological_processendosomal lumen acidification
d0061795biological_processGolgi lumen acidification
d1902600biological_processproton transmembrane transport
F0000139cellular_componentGolgi membrane
F0000221cellular_componentvacuolar proton-transporting V-type ATPase, V1 domain
F0000329cellular_componentfungal-type vacuole membrane
F0005515molecular_functionprotein binding
F0005773cellular_componentvacuole
F0005774cellular_componentvacuolar membrane
F0007035biological_processvacuolar acidification
F0016020cellular_componentmembrane
F0016471cellular_componentvacuolar proton-transporting V-type ATPase complex
F0033176cellular_componentproton-transporting V-type ATPase complex
F0033180cellular_componentproton-transporting V-type ATPase, V1 domain
F0034220biological_processmonoatomic ion transmembrane transport
F0046961molecular_functionproton-transporting ATPase activity, rotational mechanism
F0048388biological_processendosomal lumen acidification
F0061795biological_processGolgi lumen acidification
F1902600biological_processproton transmembrane transport
g0000139cellular_componentGolgi membrane
g0000220cellular_componentvacuolar proton-transporting V-type ATPase, V0 domain
g0000329cellular_componentfungal-type vacuole membrane
g0005773cellular_componentvacuole
g0005774cellular_componentvacuolar membrane
g0006623biological_processprotein targeting to vacuole
g0006878biological_processintracellular copper ion homeostasis
g0006879biological_processintracellular iron ion homeostasis
g0006897biological_processendocytosis
g0007033biological_processvacuole organization
g0007035biological_processvacuolar acidification
g0015078molecular_functionproton transmembrane transporter activity
g0016020cellular_componentmembrane
g0016471cellular_componentvacuolar proton-transporting V-type ATPase complex
g0033176cellular_componentproton-transporting V-type ATPase complex
g0033177cellular_componentproton-transporting two-sector ATPase complex, proton-transporting domain
g0033179cellular_componentproton-transporting V-type ATPase, V0 domain
g0046961molecular_functionproton-transporting ATPase activity, rotational mechanism
g0048388biological_processendosomal lumen acidification
g0061795biological_processGolgi lumen acidification
g1902600biological_processproton transmembrane transport
h0000139cellular_componentGolgi membrane
h0000220cellular_componentvacuolar proton-transporting V-type ATPase, V0 domain
h0000329cellular_componentfungal-type vacuole membrane
h0005773cellular_componentvacuole
h0005774cellular_componentvacuolar membrane
h0006623biological_processprotein targeting to vacuole
h0006878biological_processintracellular copper ion homeostasis
h0006879biological_processintracellular iron ion homeostasis
h0006897biological_processendocytosis
h0007033biological_processvacuole organization
h0007035biological_processvacuolar acidification
h0015078molecular_functionproton transmembrane transporter activity
h0016020cellular_componentmembrane
h0016471cellular_componentvacuolar proton-transporting V-type ATPase complex
h0033176cellular_componentproton-transporting V-type ATPase complex
h0033177cellular_componentproton-transporting two-sector ATPase complex, proton-transporting domain
h0033179cellular_componentproton-transporting V-type ATPase, V0 domain
h0046961molecular_functionproton-transporting ATPase activity, rotational mechanism
h0048388biological_processendosomal lumen acidification
h0061795biological_processGolgi lumen acidification
h1902600biological_processproton transmembrane transport
i0000139cellular_componentGolgi membrane
i0000220cellular_componentvacuolar proton-transporting V-type ATPase, V0 domain
i0000329cellular_componentfungal-type vacuole membrane
i0005773cellular_componentvacuole
i0005774cellular_componentvacuolar membrane
i0006623biological_processprotein targeting to vacuole
i0006878biological_processintracellular copper ion homeostasis
i0006879biological_processintracellular iron ion homeostasis
i0006897biological_processendocytosis
i0007033biological_processvacuole organization
i0007035biological_processvacuolar acidification
i0015078molecular_functionproton transmembrane transporter activity
i0016020cellular_componentmembrane
i0016471cellular_componentvacuolar proton-transporting V-type ATPase complex
i0033176cellular_componentproton-transporting V-type ATPase complex
i0033177cellular_componentproton-transporting two-sector ATPase complex, proton-transporting domain
i0033179cellular_componentproton-transporting V-type ATPase, V0 domain
i0046961molecular_functionproton-transporting ATPase activity, rotational mechanism
i0048388biological_processendosomal lumen acidification
i0061795biological_processGolgi lumen acidification
i1902600biological_processproton transmembrane transport
j0000139cellular_componentGolgi membrane
j0000220cellular_componentvacuolar proton-transporting V-type ATPase, V0 domain
j0000329cellular_componentfungal-type vacuole membrane
j0005773cellular_componentvacuole
j0005774cellular_componentvacuolar membrane
j0006623biological_processprotein targeting to vacuole
j0006878biological_processintracellular copper ion homeostasis
j0006879biological_processintracellular iron ion homeostasis
j0006897biological_processendocytosis
j0007033biological_processvacuole organization
j0007035biological_processvacuolar acidification
j0015078molecular_functionproton transmembrane transporter activity
j0016020cellular_componentmembrane
j0016471cellular_componentvacuolar proton-transporting V-type ATPase complex
j0033176cellular_componentproton-transporting V-type ATPase complex
j0033177cellular_componentproton-transporting two-sector ATPase complex, proton-transporting domain
j0033179cellular_componentproton-transporting V-type ATPase, V0 domain
j0046961molecular_functionproton-transporting ATPase activity, rotational mechanism
j0048388biological_processendosomal lumen acidification
j0061795biological_processGolgi lumen acidification
j1902600biological_processproton transmembrane transport
k0000139cellular_componentGolgi membrane
k0000220cellular_componentvacuolar proton-transporting V-type ATPase, V0 domain
k0000329cellular_componentfungal-type vacuole membrane
k0005773cellular_componentvacuole
k0005774cellular_componentvacuolar membrane
k0006623biological_processprotein targeting to vacuole
k0006878biological_processintracellular copper ion homeostasis
k0006879biological_processintracellular iron ion homeostasis
k0006897biological_processendocytosis
k0007033biological_processvacuole organization
k0007035biological_processvacuolar acidification
k0015078molecular_functionproton transmembrane transporter activity
k0016020cellular_componentmembrane
k0016471cellular_componentvacuolar proton-transporting V-type ATPase complex
k0033176cellular_componentproton-transporting V-type ATPase complex
k0033177cellular_componentproton-transporting two-sector ATPase complex, proton-transporting domain
k0033179cellular_componentproton-transporting V-type ATPase, V0 domain
k0046961molecular_functionproton-transporting ATPase activity, rotational mechanism
k0048388biological_processendosomal lumen acidification
k0061795biological_processGolgi lumen acidification
k1902600biological_processproton transmembrane transport
l0000139cellular_componentGolgi membrane
l0000220cellular_componentvacuolar proton-transporting V-type ATPase, V0 domain
l0000329cellular_componentfungal-type vacuole membrane
l0005773cellular_componentvacuole
l0005774cellular_componentvacuolar membrane
l0006623biological_processprotein targeting to vacuole
l0006878biological_processintracellular copper ion homeostasis
l0006879biological_processintracellular iron ion homeostasis
l0006897biological_processendocytosis
l0007033biological_processvacuole organization
l0007035biological_processvacuolar acidification
l0015078molecular_functionproton transmembrane transporter activity
l0016020cellular_componentmembrane
l0016471cellular_componentvacuolar proton-transporting V-type ATPase complex
l0033176cellular_componentproton-transporting V-type ATPase complex
l0033177cellular_componentproton-transporting two-sector ATPase complex, proton-transporting domain
l0033179cellular_componentproton-transporting V-type ATPase, V0 domain
l0046961molecular_functionproton-transporting ATPase activity, rotational mechanism
l0048388biological_processendosomal lumen acidification
l0061795biological_processGolgi lumen acidification
l1902600biological_processproton transmembrane transport
m0000139cellular_componentGolgi membrane
m0000220cellular_componentvacuolar proton-transporting V-type ATPase, V0 domain
m0000329cellular_componentfungal-type vacuole membrane
m0005773cellular_componentvacuole
m0005774cellular_componentvacuolar membrane
m0006623biological_processprotein targeting to vacuole
m0006878biological_processintracellular copper ion homeostasis
m0006879biological_processintracellular iron ion homeostasis
m0006897biological_processendocytosis
m0007033biological_processvacuole organization
m0007035biological_processvacuolar acidification
m0015078molecular_functionproton transmembrane transporter activity
m0016020cellular_componentmembrane
m0016471cellular_componentvacuolar proton-transporting V-type ATPase complex
m0033176cellular_componentproton-transporting V-type ATPase complex
m0033177cellular_componentproton-transporting two-sector ATPase complex, proton-transporting domain
m0033179cellular_componentproton-transporting V-type ATPase, V0 domain
m0046961molecular_functionproton-transporting ATPase activity, rotational mechanism
m0048388biological_processendosomal lumen acidification
m0061795biological_processGolgi lumen acidification
m1902600biological_processproton transmembrane transport
n0000139cellular_componentGolgi membrane
n0000220cellular_componentvacuolar proton-transporting V-type ATPase, V0 domain
n0000329cellular_componentfungal-type vacuole membrane
n0005773cellular_componentvacuole
n0005774cellular_componentvacuolar membrane
n0006623biological_processprotein targeting to vacuole
n0006878biological_processintracellular copper ion homeostasis
n0006879biological_processintracellular iron ion homeostasis
n0006897biological_processendocytosis
n0007033biological_processvacuole organization
n0007035biological_processvacuolar acidification
n0015078molecular_functionproton transmembrane transporter activity
n0016020cellular_componentmembrane
n0016471cellular_componentvacuolar proton-transporting V-type ATPase complex
n0033176cellular_componentproton-transporting V-type ATPase complex
n0033177cellular_componentproton-transporting two-sector ATPase complex, proton-transporting domain
n0033179cellular_componentproton-transporting V-type ATPase, V0 domain
n0046961molecular_functionproton-transporting ATPase activity, rotational mechanism
n0048388biological_processendosomal lumen acidification
n0061795biological_processGolgi lumen acidification
n1902600biological_processproton transmembrane transport
o0000139cellular_componentGolgi membrane
o0000220cellular_componentvacuolar proton-transporting V-type ATPase, V0 domain
o0000324cellular_componentfungal-type vacuole
o0000329cellular_componentfungal-type vacuole membrane
o0005773cellular_componentvacuole
o0005774cellular_componentvacuolar membrane
o0007035biological_processvacuolar acidification
o0015078molecular_functionproton transmembrane transporter activity
o0016020cellular_componentmembrane
o0016471cellular_componentvacuolar proton-transporting V-type ATPase complex
o0033176cellular_componentproton-transporting V-type ATPase complex
o0033177cellular_componentproton-transporting two-sector ATPase complex, proton-transporting domain
o0033179cellular_componentproton-transporting V-type ATPase, V0 domain
o0046961molecular_functionproton-transporting ATPase activity, rotational mechanism
o0048388biological_processendosomal lumen acidification
o0061795biological_processGolgi lumen acidification
o0071944cellular_componentcell periphery
o1902600biological_processproton transmembrane transport
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues35
DetailsTOPO_DOM: Vacuolar => ECO:0000255
ChainResidueDetails
oMET1-TYR14
jMET1-TYR8
jCYS75-GLN90
jASN151-CYS160
kMET1-TYR8
kCYS75-GLN90
kASN151-CYS160
lMET1-TYR8
lCYS75-GLN90
lASN151-CYS160
mMET1-TYR8
oALA81-HIS98
mCYS75-GLN90
mASN151-CYS160
nMET1-TYR8
nCYS75-GLN90
nASN151-CYS160
oASN159-GLU164
hMET1-TYR8
hCYS75-GLN90
hASN151-CYS160
iMET1-TYR8
iCYS75-GLN90
iASN151-CYS160

site_idSWS_FT_FI2
Number of Residues88
DetailsTRANSMEM: Helical => ECO:0000255
ChainResidueDetails
oALA15-GLY37
iILE54-VAL74
iLEU91-GLY112
iLEU125-LEU150
jALA9-GLY31
jILE54-VAL74
jLEU91-GLY112
jLEU125-LEU150
kALA9-GLY31
kILE54-VAL74
kLEU91-GLY112
oLEU60-ILE80
kLEU125-LEU150
lALA9-GLY31
lILE54-VAL74
lLEU91-GLY112
lLEU125-LEU150
mALA9-GLY31
mILE54-VAL74
mLEU91-GLY112
mLEU125-LEU150
nALA9-GLY31
oLEU99-GLY120
nILE54-VAL74
nLEU91-GLY112
nLEU125-LEU150
oLEU133-LEU158
hALA9-GLY31
hILE54-VAL74
hLEU91-GLY112
hLEU125-LEU150
iALA9-GLY31

site_idSWS_FT_FI3
Number of Residues32
DetailsTOPO_DOM: Cytoplasmic => ECO:0000255
ChainResidueDetails
oTHR38-SER59
kASP113-ARG124
lTHR32-ASN53
lASP113-ARG124
mTHR32-ASN53
mASP113-ARG124
nTHR32-ASN53
nASP113-ARG124
oASP121-ARG132
hTHR32-ASN53
hASP113-ARG124
iTHR32-ASN53
iASP113-ARG124
jTHR32-ASN53
jASP113-ARG124
kTHR32-ASN53

site_idSWS_FT_FI4
Number of Residues1
DetailsSITE: Essential for proton translocation => ECO:0000269|PubMed:9030535
ChainResidueDetails
oGLU145
hGLU137
iGLU137
jGLU137
kGLU137
lGLU137
mGLU137
nGLU137

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PDB entries from 2024-07-10

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