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8E9B

Cryo-EM structure of S. pombe Arp2/3 complex in the branch junction

Functional Information from GO Data
ChainGOidnamespacecontents
A0000281biological_processmitotic cytokinesis
A0003779molecular_functionactin binding
A0005515molecular_functionprotein binding
A0005524molecular_functionATP binding
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0005856cellular_componentcytoskeleton
A0005885cellular_componentArp2/3 protein complex
A0006897biological_processendocytosis
A0030036biological_processactin cytoskeleton organization
A0030041biological_processactin filament polymerization
A0030479cellular_componentactin cortical patch
A0032153cellular_componentcell division site
A0034314biological_processArp2/3 complex-mediated actin nucleation
A0044396biological_processactin cortical patch organization
A0051015molecular_functionactin filament binding
A0051285cellular_componentcell cortex of cell tip
B0000147biological_processactin cortical patch assembly
B0003779molecular_functionactin binding
B0005524molecular_functionATP binding
B0005737cellular_componentcytoplasm
B0005856cellular_componentcytoskeleton
B0005885cellular_componentArp2/3 protein complex
B0005938cellular_componentcell cortex
B0006897biological_processendocytosis
B0030479cellular_componentactin cortical patch
B0031097cellular_componentmedial cortex
B0034314biological_processArp2/3 complex-mediated actin nucleation
B0051015molecular_functionactin filament binding
B0051285cellular_componentcell cortex of cell tip
C0000147biological_processactin cortical patch assembly
C0003779molecular_functionactin binding
C0005737cellular_componentcytoplasm
C0005829cellular_componentcytosol
C0005856cellular_componentcytoskeleton
C0005885cellular_componentArp2/3 protein complex
C0006897biological_processendocytosis
C0015629cellular_componentactin cytoskeleton
C0030036biological_processactin cytoskeleton organization
C0030479cellular_componentactin cortical patch
C0030866biological_processcortical actin cytoskeleton organization
C0032153cellular_componentcell division site
C0034314biological_processArp2/3 complex-mediated actin nucleation
C0051015molecular_functionactin filament binding
C0051286cellular_componentcell tip
D0000147biological_processactin cortical patch assembly
D0003779molecular_functionactin binding
D0005200molecular_functionstructural constituent of cytoskeleton
D0005634cellular_componentnucleus
D0005737cellular_componentcytoplasm
D0005829cellular_componentcytosol
D0005856cellular_componentcytoskeleton
D0005885cellular_componentArp2/3 protein complex
D0006897biological_processendocytosis
D0015629cellular_componentactin cytoskeleton
D0030041biological_processactin filament polymerization
D0030479cellular_componentactin cortical patch
D0032153cellular_componentcell division site
D0034314biological_processArp2/3 complex-mediated actin nucleation
D0051015molecular_functionactin filament binding
D0051286cellular_componentcell tip
E0000147biological_processactin cortical patch assembly
E0003779molecular_functionactin binding
E0005634cellular_componentnucleus
E0005737cellular_componentcytoplasm
E0005826cellular_componentactomyosin contractile ring
E0005829cellular_componentcytosol
E0005856cellular_componentcytoskeleton
E0005885cellular_componentArp2/3 protein complex
E0006897biological_processendocytosis
E0007163biological_processestablishment or maintenance of cell polarity
E0030479cellular_componentactin cortical patch
E0030833biological_processregulation of actin filament polymerization
E0032153cellular_componentcell division site
E0032432cellular_componentactin filament bundle
E0034314biological_processArp2/3 complex-mediated actin nucleation
E0044396biological_processactin cortical patch organization
E0051015molecular_functionactin filament binding
E0051286cellular_componentcell tip
F0000147biological_processactin cortical patch assembly
F0003779molecular_functionactin binding
F0005634cellular_componentnucleus
F0005737cellular_componentcytoplasm
F0005829cellular_componentcytosol
F0005856cellular_componentcytoskeleton
F0005885cellular_componentArp2/3 protein complex
F0006897biological_processendocytosis
F0015629cellular_componentactin cytoskeleton
F0030041biological_processactin filament polymerization
F0030479cellular_componentactin cortical patch
F0034314biological_processArp2/3 complex-mediated actin nucleation
F0051015molecular_functionactin filament binding
G0000147biological_processactin cortical patch assembly
G0003779molecular_functionactin binding
G0005634cellular_componentnucleus
G0005737cellular_componentcytoplasm
G0005829cellular_componentcytosol
G0005856cellular_componentcytoskeleton
G0005885cellular_componentArp2/3 protein complex
G0006897biological_processendocytosis
G0015629cellular_componentactin cytoskeleton
G0030479cellular_componentactin cortical patch
G0030833biological_processregulation of actin filament polymerization
G0034314biological_processArp2/3 complex-mediated actin nucleation
G0043332cellular_componentmating projection tip
G0051015molecular_functionactin filament binding
H0001725cellular_componentstress fiber
H0005515molecular_functionprotein binding
H0005524molecular_functionATP binding
H0005737cellular_componentcytoplasm
H0005856cellular_componentcytoskeleton
H0005865cellular_componentstriated muscle thin filament
H0005884cellular_componentactin filament
H0016787molecular_functionhydrolase activity
H0030240biological_processskeletal muscle thin filament assembly
H0048741biological_processskeletal muscle fiber development
I0001725cellular_componentstress fiber
I0005515molecular_functionprotein binding
I0005524molecular_functionATP binding
I0005737cellular_componentcytoplasm
I0005856cellular_componentcytoskeleton
I0005865cellular_componentstriated muscle thin filament
I0005884cellular_componentactin filament
I0016787molecular_functionhydrolase activity
I0030240biological_processskeletal muscle thin filament assembly
I0048741biological_processskeletal muscle fiber development
M0001725cellular_componentstress fiber
M0005515molecular_functionprotein binding
M0005524molecular_functionATP binding
M0005737cellular_componentcytoplasm
M0005856cellular_componentcytoskeleton
M0005865cellular_componentstriated muscle thin filament
M0005884cellular_componentactin filament
M0016787molecular_functionhydrolase activity
M0030240biological_processskeletal muscle thin filament assembly
M0048741biological_processskeletal muscle fiber development
N0001725cellular_componentstress fiber
N0005515molecular_functionprotein binding
N0005524molecular_functionATP binding
N0005737cellular_componentcytoplasm
N0005856cellular_componentcytoskeleton
N0005865cellular_componentstriated muscle thin filament
N0005884cellular_componentactin filament
N0016787molecular_functionhydrolase activity
N0030240biological_processskeletal muscle thin filament assembly
N0048741biological_processskeletal muscle fiber development
O0001725cellular_componentstress fiber
O0005515molecular_functionprotein binding
O0005524molecular_functionATP binding
O0005737cellular_componentcytoplasm
O0005856cellular_componentcytoskeleton
O0005865cellular_componentstriated muscle thin filament
O0005884cellular_componentactin filament
O0016787molecular_functionhydrolase activity
O0030240biological_processskeletal muscle thin filament assembly
O0048741biological_processskeletal muscle fiber development
P0001725cellular_componentstress fiber
P0005515molecular_functionprotein binding
P0005524molecular_functionATP binding
P0005737cellular_componentcytoplasm
P0005856cellular_componentcytoskeleton
P0005865cellular_componentstriated muscle thin filament
P0005884cellular_componentactin filament
P0016787molecular_functionhydrolase activity
P0030240biological_processskeletal muscle thin filament assembly
P0048741biological_processskeletal muscle fiber development
Q0001725cellular_componentstress fiber
Q0005515molecular_functionprotein binding
Q0005524molecular_functionATP binding
Q0005737cellular_componentcytoplasm
Q0005856cellular_componentcytoskeleton
Q0005865cellular_componentstriated muscle thin filament
Q0005884cellular_componentactin filament
Q0016787molecular_functionhydrolase activity
Q0030240biological_processskeletal muscle thin filament assembly
Q0048741biological_processskeletal muscle fiber development
R0001725cellular_componentstress fiber
R0005515molecular_functionprotein binding
R0005524molecular_functionATP binding
R0005737cellular_componentcytoplasm
R0005856cellular_componentcytoskeleton
R0005865cellular_componentstriated muscle thin filament
R0005884cellular_componentactin filament
R0016787molecular_functionhydrolase activity
R0030240biological_processskeletal muscle thin filament assembly
R0048741biological_processskeletal muscle fiber development
Functional Information from PROSITE/UniProt
site_idPS00406
Number of Residues11
DetailsACTINS_1 Actins signature 1. YVGDEAQs.KRG
ChainResidueDetails
MTYR53-GLY63

site_idPS00432
Number of Residues9
DetailsACTINS_2 Actins signature 2. WITKqEYDE
ChainResidueDetails
MTRP356-GLU364

site_idPS01132
Number of Residues13
DetailsACTINS_ACT_LIKE Actins and actin-related proteins signature. LLTEPpLNPpeNR
ChainResidueDetails
ALEU127-ARG139
BLEU104-ARG116
MLEU104-ARG116

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues8
DetailsMOD_RES: N-acetylaspartate; in Actin, alpha skeletal muscle => ECO:0000269|PubMed:456601
ChainResidueDetails
MASP1
NASP1
OASP1
PASP1
QASP1
RASP1
HASP1
IASP1

site_idSWS_FT_FI2
Number of Residues16
DetailsMOD_RES: Methionine (R)-sulfoxide => ECO:0000250|UniProtKB:P68134
ChainResidueDetails
MMET44
QMET47
RMET44
RMET47
HMET44
HMET47
IMET44
IMET47
MMET47
NMET44
NMET47
OMET44
OMET47
PMET44
PMET47
QMET44

site_idSWS_FT_FI3
Number of Residues8
DetailsMOD_RES: Tele-methylhistidine => ECO:0000269|PubMed:12356759, ECO:0007744|PDB:1MDU
ChainResidueDetails
MHIC73
NHIC73
OHIC73
PHIC73
QHIC73
RHIC73
HHIC73
IHIC73

site_idSWS_FT_FI4
Number of Residues8
DetailsMOD_RES: N6-methyllysine => ECO:0000250|UniProtKB:P68133
ChainResidueDetails
MLYS84
NLYS84
OLYS84
PLYS84
QLYS84
RLYS84
HLYS84
ILYS84

222415

PDB entries from 2024-07-10

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