8E6J
3H03 Fab in complex with influenza virus neuraminidase from A/Brevig Mission/1/1918 (H1N1)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004308 | molecular_function | exo-alpha-sialidase activity |
| A | 0005975 | biological_process | carbohydrate metabolic process |
| A | 0016020 | cellular_component | membrane |
| A | 0033644 | cellular_component | host cell membrane |
| A | 0046761 | biological_process | viral budding from plasma membrane |
| A | 0055036 | cellular_component | virion membrane |
| B | 0004308 | molecular_function | exo-alpha-sialidase activity |
| B | 0005975 | biological_process | carbohydrate metabolic process |
| B | 0016020 | cellular_component | membrane |
| B | 0033644 | cellular_component | host cell membrane |
| B | 0046761 | biological_process | viral budding from plasma membrane |
| B | 0055036 | cellular_component | virion membrane |
| C | 0004308 | molecular_function | exo-alpha-sialidase activity |
| C | 0005975 | biological_process | carbohydrate metabolic process |
| C | 0016020 | cellular_component | membrane |
| C | 0033644 | cellular_component | host cell membrane |
| C | 0046761 | biological_process | viral budding from plasma membrane |
| C | 0055036 | cellular_component | virion membrane |
| D | 0004308 | molecular_function | exo-alpha-sialidase activity |
| D | 0005975 | biological_process | carbohydrate metabolic process |
| D | 0016020 | cellular_component | membrane |
| D | 0033644 | cellular_component | host cell membrane |
| D | 0046761 | biological_process | viral budding from plasma membrane |
| D | 0055036 | cellular_component | virion membrane |
Functional Information from PROSITE/UniProt
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH |
| Chain | Residue | Details |
| L | TYR192-HIS198 | |
| H | TYR194-HIS200 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | ACT_SITE: Proton donor/acceptor => ECO:0000255|HAMAP-Rule:MF_04071 |
| Chain | Residue | Details |
| A | ASP151 | |
| B | ASP151 | |
| C | ASP151 | |
| D | ASP151 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | ACT_SITE: Nucleophile => ECO:0000255|HAMAP-Rule:MF_04071 |
| Chain | Residue | Details |
| A | TYR406 | |
| B | TYR406 | |
| C | TYR406 | |
| D | TYR406 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 20 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_04071 |
| Chain | Residue | Details |
| A | ARG118 | |
| A | ARG152 | |
| A | GLU276 | |
| A | ARG292 | |
| A | ARG371 | |
| B | ARG118 | |
| B | ARG152 | |
| B | GLU276 | |
| B | ARG292 | |
| B | ARG371 | |
| C | ARG118 | |
| C | ARG152 | |
| C | GLU276 | |
| C | ARG292 | |
| C | ARG371 | |
| D | ARG118 | |
| D | ARG152 | |
| D | GLU276 | |
| D | ARG292 | |
| D | ARG371 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 16 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_04071, ECO:0000269|PubMed:18715929 |
| Chain | Residue | Details |
| A | ASP293 | |
| A | GLY297 | |
| A | ASP324 | |
| A | ASN347 | |
| B | ASP293 | |
| B | GLY297 | |
| B | ASP324 | |
| B | ASN347 | |
| C | ASP293 | |
| C | GLY297 | |
| C | ASP324 | |
| C | ASN347 | |
| D | ASP293 | |
| D | GLY297 | |
| D | ASP324 | |
| D | ASN347 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 8 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04071 |
| Chain | Residue | Details |
| A | ASN88 | |
| A | ASN234 | |
| B | ASN88 | |
| B | ASN234 | |
| C | ASN88 | |
| C | ASN234 | |
| D | ASN88 | |
| D | ASN234 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 4 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine; by host => ECO:0000255|HAMAP-Rule:MF_04071, ECO:0000269|PubMed:18715929 |
| Chain | Residue | Details |
| A | ASN146 | |
| B | ASN146 | |
| C | ASN146 | |
| D | ASN146 |
