Functional Information from GO Data
Chain | GOid | namespace | contents |
F | 0003700 | molecular_function | DNA-binding transcription factor activity |
F | 0006355 | biological_process | regulation of DNA-templated transcription |
F | 0006357 | biological_process | regulation of transcription by RNA polymerase II |
F | 0043565 | molecular_function | sequence-specific DNA binding |
Functional Information from PROSITE/UniProt
site_id | PS00345 |
Number of Residues | 9 |
Details | ETS_DOMAIN_1 Ets-domain signature 1. LYQFLLDLL |
Chain | Residue | Details |
F | LEU172-LEU180 | |
site_id | PS00346 |
Number of Residues | 16 |
Details | ETS_DOMAIN_2 Ets-domain signature 2. RkkMtYQkMARALRnY |
Chain | Residue | Details |
F | ARG220-TYR235 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
F | ILE170-SER253 | |
site_id | SWS_FT_FI2 |
Number of Residues | 1 |
Details | BINDING: forms a salt bridge with the phosphate backbone of the opposite strand downstream of the GGAA core sequence => ECO:0000250|UniProtKB:P17433 |
Chain | Residue | Details |
F | LYS217 | |
site_id | SWS_FT_FI3 |
Number of Residues | 2 |
Details | BINDING: contacts bases in the GGAA sequence in the major groove => ECO:0000250|UniProtKB:P17433 |
Chain | Residue | Details |
F | ARG230 | |
F | ARG233 | |
site_id | SWS_FT_FI4 |
Number of Residues | 1 |
Details | BINDING: contacts the phosphate backbone of the GGAA sequence in the minor groove upstream => ECO:0000250|UniProtKB:P17433 |
Chain | Residue | Details |
F | LYS243 | |